Allogeneic Stem Cell Transplantation

Author : Gerard Socie,Robert Zeiser,Bruce R. Blazar
Publisher : Academic Press
Page : 430 pages
File Size : 41,5 Mb
Release : 2018-11-22
Category : Science
ISBN : 9780128134399

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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation by Gerard Socie,Robert Zeiser,Bruce R. Blazar Pdf

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

Author : Hillard M. Lazarus,Mary J. Laughlin
Publisher : Springer Science & Business Media
Page : 881 pages
File Size : 48,6 Mb
Release : 2010-03-02
Category : Medical
ISBN : 9781597454780

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Allogeneic Stem Cell Transplantation by Hillard M. Lazarus,Mary J. Laughlin Pdf

Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 42,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Michelle Kenyon,Aleksandra Babic
Publisher : Springer
Page : 311 pages
File Size : 55,7 Mb
Release : 2018-03-14
Category : Medical
ISBN : 9783319500263

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The European Blood and Marrow Transplantation Textbook for Nurses by Michelle Kenyon,Aleksandra Babic Pdf

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Author : William K. Oh,Ajai Chari
Publisher : John Wiley & Sons
Page : 632 pages
File Size : 51,7 Mb
Release : 2019-09-30
Category : Medical
ISBN : 9781119189558

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Oncology by William K. Oh,Ajai Chari Pdf

The Mount Sinai Expert Guides provide quick access to point-of-care specialist clinical information for physicians across a range of therapeutic areas. For each specialty area, the guides emphasize: Common pitfalls in diagnosis and management How to prevent complications Diagnostic and treatment algorithms Key scientific trials Evidence-based clinical content Major society guidelines in order to summarize the very latest in diagnosis and management of diseases and related symptoms. Edited by renowned specialists from the Icahn School of Medicine at Mount Sinai, key faculty members provide the content for all chapters. To ensure consistency within each book and the series as a whole, chapters follow a unified structure throughout. Bonus features such as online case studies with related questions for self-assessment, key patient advice, and ICD codes are provided via the series companion website. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 41,8 Mb
Release : 2025
Category : Electronic
ISBN : 303144082X

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EBMT HANDBOOK by Anonim Pdf

Author : Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum
Publisher : John Wiley & Sons
Page : 1416 pages
File Size : 55,5 Mb
Release : 2015-12-14
Category : Medical
ISBN : 9781118416129

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Thomas' Hematopoietic Cell Transplantation by Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum Pdf

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Author : Anonim
Publisher : Unknown
Page : 58 pages
File Size : 49,9 Mb
Release : 1994
Category : Bone marrow
ISBN : PURD:32754066349097

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Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation by Anonim Pdf

Author : Robert J. Soiffer
Publisher : Unknown
Page : 500 pages
File Size : 55,5 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1475765878

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Stem Cell Transplantation for Hematologic Malignancies by Robert J. Soiffer Pdf

Author : Michele Malagola,Alessandro Isidori,Jacopo Peccatori,Fabio Ciceri,Raffaella Greco,Rizwan Romee,Mohamad Mohty,Domenico Russo
Publisher : Frontiers Media SA
Page : 193 pages
File Size : 46,6 Mb
Release : 2022-03-15
Category : Medical
ISBN : 9782889746927

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Advances and Challenges of Allogeneic Stem Cell Transplantation by Michele Malagola,Alessandro Isidori,Jacopo Peccatori,Fabio Ciceri,Raffaella Greco,Rizwan Romee,Mohamad Mohty,Domenico Russo Pdf

Author : Frank Leonard Johnson,Carl Pochedly
Publisher : Unknown
Page : 570 pages
File Size : 46,7 Mb
Release : 1990
Category : Bone marrow
ISBN : UOM:39015016980651

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Bone Marrow Transplantation in Children by Frank Leonard Johnson,Carl Pochedly Pdf

Author : Georgia B. Vogelsang,Steven Z. Pavletic
Publisher : Cambridge University Press
Page : 427 pages
File Size : 50,6 Mb
Release : 2009-04-20
Category : Medical
ISBN : 9781139478892

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Chronic Graft Versus Host Disease by Georgia B. Vogelsang,Steven Z. Pavletic Pdf

Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant.

Author : Sanjeev Kumar Sharma
Publisher : Springer Nature
Page : 962 pages
File Size : 46,6 Mb
Release : 2023-07-24
Category : Medical
ISBN : 9789811958021

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Basics of Hematopoietic Stem Cell Transplant by Sanjeev Kumar Sharma Pdf

This book is quick guide on the hematopoietic stem cell transplant (SCT), also called bone marrow transplant (BMT) - an evolving field of hematology and hemato-oncology. This book covers the various types of stem cell transplants like autologous and allogeneic stem cell transplants, indications, ways of doing a transplant, and stem cell transplants basic principles. Written in a question-answer format, readers will find it more interesting as one question sequentially leads to another. This book explains the complications of SCT in individual chapters along with the biology of T cells which are the most important cells involved in the success of SCT This book is beneficial to the budding hematologists, oncologists, and postgraduates interested in SCT and helps students in their exams. The book would be helpful for readers globally as SCT is a procedure done worldwide and is an ever-increasing field for treating various benign and malignant hematological diseases.

Author : Stefan O. Ciurea,Rupert Handgretinger
Publisher : Springer
Page : 337 pages
File Size : 49,6 Mb
Release : 2018-05-03
Category : Medical
ISBN : 9783319543109

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Haploidentical Transplantation by Stefan O. Ciurea,Rupert Handgretinger Pdf

In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.

Author : Mary J. Laughlin,Hillard M. Lazarus
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 45,9 Mb
Release : 2003
Category : Blood
ISBN : UOM:39015055860145

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Allogeneic Stem Cell Transplantation by Mary J. Laughlin,Hillard M. Lazarus Pdf

Leading authorities provide a valuable account of the clinical and labratory issue related to allogeneic stem cell transplantation. Key chapters feature such topics as the selection of optimal inrelated allogeneic grafts for patients with hematologic malignancies; issues related to stem cell mobilization in normal donors; allogeneic peripheral blood cell vs marrow-derived transplantation; umbilical cord blood as a new stem cell source; kinetics of immune reconstitution post allogeneic transplantation; the role of allogeneic transplantation in breast cancer, and; the application of mini-conditioning in allogeneic grafting. The book will serve as a guide in development of innovative clinical and labratory inquiry in the field of allogeneic transplantation for all clinicians and labratory investigators focused on hematopoetic stem cells and immune biology research.