Autophagy Biology And Diseases

Autophagy Biology And Diseases Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Autophagy Biology And Diseases book. This book definitely worth reading, it is an incredibly well-written.

Autophagy: Biology and Diseases

Author : Zheng-Hong Qin
Publisher : Springer Nature
Page : 727 pages
File Size : 41,6 Mb
Release : 2019-11-27
Category : Science
ISBN : 9789811506024

Get Book

Autophagy: Biology and Diseases by Zheng-Hong Qin Pdf

This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.

Autophagy: Biology and Diseases

Author : Zhiping Xie
Publisher : Springer Nature
Page : 453 pages
File Size : 46,6 Mb
Release : 2021-07-14
Category : Medical
ISBN : 9789811628306

Get Book

Autophagy: Biology and Diseases by Zhiping Xie Pdf

This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 3 focuses on the technical aspects of autophagy research. It is comprised of two parts. The first part discusses the basic process of autophagy, including its overall classification and individual stages in the life cycle of autophagosomes. The second part discusses the tools, strategies, and model systems in current autophagy research, including cell and animal models, detection and manipulation methods, as well as screening, genomic, proteomic and bioinformatic approaches. The book is written and edited by a team of active scientists. It is intended as a practical reference resource for interested researchers to get started on autophagy studies.

Autophagy: Biology and Diseases

Author : Weidong Le
Publisher : Springer Nature
Page : 734 pages
File Size : 49,9 Mb
Release : 2020-07-15
Category : Medical
ISBN : 9789811542725

Get Book

Autophagy: Biology and Diseases by Weidong Le Pdf

This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine

Autophagy in Health and Disease

Author : Beverly Rothermel,Abhinav Diwan
Publisher : Elsevier
Page : 456 pages
File Size : 43,8 Mb
Release : 2021-09-22
Category : Science
ISBN : 9780128220047

Get Book

Autophagy in Health and Disease by Beverly Rothermel,Abhinav Diwan Pdf

Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target. Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study. Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology Offers extended coverage of the mechanisms that mediate autophagy Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis Highlights important questions that remain to be addressed

Autophagy in Health and Disease

Author : Kursad Turksen
Publisher : Springer
Page : 177 pages
File Size : 48,8 Mb
Release : 2018-10-06
Category : Science
ISBN : 9783319981468

Get Book

Autophagy in Health and Disease by Kursad Turksen Pdf

This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.

Autophagy at the Cell, Tissue and Organismal Level

Author : Eleftherios Karanasios,Nicholas T. Ktistakis
Publisher : Springer
Page : 103 pages
File Size : 45,9 Mb
Release : 2016-04-23
Category : Science
ISBN : 9783319331454

Get Book

Autophagy at the Cell, Tissue and Organismal Level by Eleftherios Karanasios,Nicholas T. Ktistakis Pdf

This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.

Autophagy and Signaling

Author : Esther Wong
Publisher : CRC Press
Page : 553 pages
File Size : 42,9 Mb
Release : 2017-09-18
Category : Science
ISBN : 9781351646970

Get Book

Autophagy and Signaling by Esther Wong Pdf

Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.

Autophagosome and Phagosome

Author : Vojo Deretic
Publisher : Humana Press
Page : 455 pages
File Size : 42,7 Mb
Release : 2008-04-24
Category : Science
ISBN : 1588298531

Get Book

Autophagosome and Phagosome by Vojo Deretic Pdf

Autophagy and phagocytosis are distinct yet partially morphologically similar processes. Understanding them is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. This book presents autophagosome and phagosome methods for novices and advanced researchers alike. Comprehensive and forward-thinking, the book offers a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections.

Autophagy

Author : Nikolai Gorbunov
Publisher : Unknown
Page : 0 pages
File Size : 45,8 Mb
Release : 2012
Category : Autophagic vacuoles
ISBN : 1619422662

Get Book

Autophagy by Nikolai Gorbunov Pdf

This book gives an up-to-date overview of the biomedical aspects of autophagy research, a large interdisciplinary field emerging on intersection of (i) cell, developmental, and cancer biology, (ii) tissue remodelling and plasticity, ageing and longevity; (iii) immunology, microbiology, toxicology, and pathobiology; (iv) regenerative and adaptive biomedicine; and (v) pharmacology.

Autophagy in Current Trends in Cellular Physiology and Pathology

Author : Nikolai Gorbunov,E. Marion Schneider
Publisher : BoD – Books on Demand
Page : 528 pages
File Size : 49,9 Mb
Release : 2016-11-10
Category : Science
ISBN : 9789535127260

Get Book

Autophagy in Current Trends in Cellular Physiology and Pathology by Nikolai Gorbunov,E. Marion Schneider Pdf

Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.

Autophagy in Immunity and Infection

Author : Vojo Deretic
Publisher : John Wiley & Sons
Page : 286 pages
File Size : 48,6 Mb
Release : 2006-08-21
Category : Science
ISBN : 9783527608546

Get Book

Autophagy in Immunity and Infection by Vojo Deretic Pdf

This first book to cover this new topic at the interface of cell biology, immunology and infection biology offers a unique insight as to how the innate and possibly the adaptive immune system are shaped by cellular mechanisms. Following a comprehensive introduction to autophagy, the work features cellular mechanisms and medical implications, structured according to all major pathogens, while also covering emerging infectious diseases, such as tuberculosis. Edited by one of the authors of a groundbreaking paper on this topic.

Autophagy

Author : Nikolaĭ Vasilʹevich Gorbunov
Publisher : Nova Science Publishers
Page : 379 pages
File Size : 47,6 Mb
Release : 2012-08-01
Category : Autophagic vacuoles
ISBN : 1619422816

Get Book

Autophagy by Nikolaĭ Vasilʹevich Gorbunov Pdf

This book gives an up-to-date overview of the biomedical aspects of autophagy research, a large interdisciplinary field emerging on intersection of (i) cell, developmental, and cancer biology, (ii) tissue remodeling and plasticity, aging and longevity; (iii) immunology, microbiology, toxicology, and pathobiology; (iv) regenerative and adaptive biomedicine; and (v) pharmacology.

Lysosomes

Author : Frederick R. Maxfield,James M. Willard,Shuyan Lu
Publisher : John Wiley & Sons
Page : 561 pages
File Size : 51,6 Mb
Release : 2016-06-27
Category : Medical
ISBN : 9781118645154

Get Book

Lysosomes by Frederick R. Maxfield,James M. Willard,Shuyan Lu Pdf

Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Author : M. A. Hayat
Publisher : Academic Press
Page : 622 pages
File Size : 42,8 Mb
Release : 2017-09-07
Category : Medical
ISBN : 9780128121474

Get Book

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by M. A. Hayat Pdf

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms. Presents the most advanced information regarding the role of the autophagic system in life and death States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease Authored by global leaders in the field, bringing the broadest, most expert coverage available

Autophagy in Current Trends in Cellular Physiology and Pathology

Author : Marion Schneider,Nikolai V. Gorbunov
Publisher : Unknown
Page : 526 pages
File Size : 46,8 Mb
Release : 2016
Category : Cytology
ISBN : 953514152X

Get Book

Autophagy in Current Trends in Cellular Physiology and Pathology by Marion Schneider,Nikolai V. Gorbunov Pdf

Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.