Chloroquine For Cancer Covid 19 And Disease

Author : Shailendra K. Saxena
Publisher : Springer
Page : 213 pages
File Size : 44,7 Mb
Release : 2021-05-14
Category : Medical
ISBN : 9811548161

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Coronavirus Disease 2019 (COVID-19) by Shailendra K. Saxena Pdf

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

Author : Justus Hope
Publisher : Unknown
Page : 128 pages
File Size : 48,8 Mb
Release : 2020-09-20
Category : Electronic
ISBN : 0998055425

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Surviving Cancer, Covid-19, and Disease by Justus Hope Pdf

Author : World Health Organization
Publisher : World Health Organization
Page : 150 pages
File Size : 45,6 Mb
Release : 1995
Category : Medical
ISBN : 9789241401043

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WHO Model Prescribing Information by World Health Organization Pdf

The second revised edition of model prescribing information for some 37 essential drugs used for the prevention and treatment of protozoal and helminthic infections. The sections on malaria, African trypanosomiasis, cestode infections, schistosomiasis, and onchocerciasis have been extensively revised in the light of new developments in the treatment of these diseases. The book is organized according to diseases, moving from amoebiasis and giardiasis to intestinal, liver, and lung flukes. Each disease or group of diseases is first introduced with concise information about its causes, mode of transmission, clinical features, and geographical prevalence, followed by general advice on prevention and treatment. Prescribing information is then provided for first-choice and alternative therapeutic and prophylactic drugs. Information includes uses, dosage and administration, contraindications and precautions, use in pregnancy, adverse effects, drug interactions, and advice on storage. Wherever relevant, prescribing precautions to be followed when treating infections in AIDS patients are clearly indicated. Some rarer parasitic diseases, such as Babesia divergens infections and meningoencephalitis due to Acanthamoeba spp, which do not respond to chemotherapy, are nonetheless presented and discussed in order to help prescribers avoid ineffective medications.

Author : David J. Browning
Publisher : Springer
Page : 291 pages
File Size : 41,8 Mb
Release : 2014-05-09
Category : Medical
ISBN : 9781493905973

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Hydroxychloroquine and Chloroquine Retinopathy by David J. Browning Pdf

Malpractice settlements are large for undetected hydroxychloroquine and chloroquine toxicity which, if untreated, can lead to permanent loss of central vision. Knowledge of the ocular toxicity of these drugs has increased during the past fifty years as their use has expanded. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why the drugs are prescribed and dosing considerations. Additionally, the book addresses practice management considerations, including coding, reimbursement and equipment costs, and the medico-legal responsibilities of the rheumatologist and of the ophthalmologist. Guidelines for the management of hydroxychloroquine and chloroquine vary around the world and differences between the guidelines of the United Kingdom, the United States, and other countries are identified. The book concludes with a collection of case examples illustrating common clinical scenarios and their management. This book is a “must-have” resource for physicians who use these drugs.

Author : Helena Jane Maier,Jane Maier Maier,Erica Bickerton,Paul Britton
Publisher : Unknown
Page : 285 pages
File Size : 55,6 Mb
Release : 2015
Category : Coronaviruses
ISBN : 1493924389

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Coronaviruses by Helena Jane Maier,Jane Maier Maier,Erica Bickerton,Paul Britton Pdf

This volume aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Coronaviruses: Methods and Protocols appeals to a wide variety of scientists because it highlights techniques that are currently used in the coronovirology field, while also discussing practices applicable to other virology fields.

Author : Uwe M. Martens
Publisher : Springer
Page : 297 pages
File Size : 53,5 Mb
Release : 2018-08-01
Category : Medical
ISBN : 9783319914398

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Small Molecules in Hematology by Uwe M. Martens Pdf

This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of precision cancer therapy is now growing rapidly, and the advances being made will mean significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. An accompanying volume addresses the use of small molecules in oncology, and the two volumes together represent the third edition of the book originally published under the same title.

Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
Page : 672 pages
File Size : 40,5 Mb
Release : 2017-04-17
Category : Medical
ISBN : 9780190628635

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CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Pdf

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Author : World Health Organization
Publisher : World Health Organization
Page : 317 pages
File Size : 54,8 Mb
Release : 2015-08-13
Category : Medical
ISBN : 9789241549127

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Guidelines for the Treatment of Malaria. Third Edition by World Health Organization Pdf

Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.

Author : Benjamin Bonavida
Publisher : Springer
Page : 308 pages
File Size : 43,5 Mb
Release : 2015-05-12
Category : Medical
ISBN : 9783319136110

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Nitric Oxide and Cancer: Pathogenesis and Therapy by Benjamin Bonavida Pdf

Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.

Author : Leonard Jan Bruce-Chwatt,Robert H. Black
Publisher : Unknown
Page : 261 pages
File Size : 45,5 Mb
Release : 1986
Category : Antimalarials
ISBN : 9241401273

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Chemotherapy of Malaria by Leonard Jan Bruce-Chwatt,Robert H. Black Pdf

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 43,9 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Author : Farid A. Badria
Publisher : BoD – Books on Demand
Page : 236 pages
File Size : 40,9 Mb
Release : 2020-12-02
Category : Medical
ISBN : 9781839685200

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Drug Repurposing by Farid A. Badria Pdf

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

Author : Douglas Altman,David Machin,Trevor Bryant,Martin Gardner
Publisher : John Wiley & Sons
Page : 256 pages
File Size : 41,8 Mb
Release : 2013-06-03
Category : Medical
ISBN : 9781118702505

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Statistics with Confidence by Douglas Altman,David Machin,Trevor Bryant,Martin Gardner Pdf

This highly popular introduction to confidence intervals has been thoroughly updated and expanded. It includes methods for using confidence intervals, with illustrative worked examples and extensive guidelines and checklists to help the novice.

Author : Michael Heinrich Seegenschmiedt,Hans-Bruno Makoski,Klaus-Rüdiger Trott,Luther W. Brady
Publisher : Springer Science & Business Media
Page : 729 pages
File Size : 52,9 Mb
Release : 2009-04-15
Category : Medical
ISBN : 9783540689430

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Radiotherapy for Non-Malignant Disorders by Michael Heinrich Seegenschmiedt,Hans-Bruno Makoski,Klaus-Rüdiger Trott,Luther W. Brady Pdf

This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

Author : Anonim
Publisher : World Scientific
Page : 72 pages
File Size : 45,7 Mb
Release : 2020-04-15
Category : Social Science
ISBN : 9789811220517

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Prevention And Control Of Covid-19 by Anonim Pdf

Shanghai COVID-19 Medical Treatment Expert Team edits this timely guide for effective prevention and control of COVID-19. Readers will obtain useful guidance on prevention and control of COVID-19 in different places ranging from homes, outdoors, workplaces, etc. You will know 'What is the purpose and significance of home quarantine?', ' When do you need to wear a mask?', 'How should you wash your hands?', 'Do you need to wear a mask in an elevator?', 'What foods are safe to eat and what are not?', 'How to deal with express parcels from major epidemic areas or other areas?' and many other useful tips.Related Link(s)