Drugs For Life

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Drugs for Life

Author : Joseph Dumit
Publisher : Duke University Press
Page : 277 pages
File Size : 53,6 Mb
Release : 2012-09-03
Category : Medical
ISBN : 9780822348719

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Drugs for Life by Joseph Dumit Pdf

Challenges our understanding of health, risks, facts, and clinical trials [Payot]

Medications for Opioid Use Disorder Save Lives

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
Publisher : National Academies Press
Page : 175 pages
File Size : 51,6 Mb
Release : 2019-06-16
Category : Medical
ISBN : 9780309486484

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Medications for Opioid Use Disorder Save Lives by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder Pdf

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Drug Repositioning

Author : Michael J. Barratt,Donald E. Frail
Publisher : John Wiley & Sons
Page : 499 pages
File Size : 50,9 Mb
Release : 2012-05-29
Category : Medical
ISBN : 9780470878279

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Drug Repositioning by Michael J. Barratt,Donald E. Frail Pdf

The how's and why's of successful drug repositioning Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning strategy. Drug Repositioning is divided into three parts: Part 1, Drug Repositioning: Business Case, Strategies, and Operational Considerations, examines the medical and commercial drivers underpinning the quest to reposition existing drugs, guiding readers through the key strategic, technical, operational, and regulatory decisions needed for successful drug repositioning programs. Part 2, Application of Technology Platforms to Uncover New Indications and Repurpose Existing Drugs, sets forth computational-based strategies, tools, and databases that have been designed for repositioning studies, screening approaches, including combinations of existing drugs, and a look at the development of chemically modified analogs of approved agents. Part 3, Academic and Non-Profit Initiatives & the Role of Alliances in the Drug Repositioning Industry, explores current investigations for repositioning drugs to treat rare and neglected diseases, which are frequently overlooked by for-profit pharmaceutical companies due to their lack of commercial return. The book's appendix provides valuable resources for drug repositioning researchers, including information on drug repositioning and reformulation companies, databases, government resources and organizations, regulatory agencies, and drug repositioning initiatives from academia and non-profits. With this book as their guide, students and pharmaceutical researchers can learn how to use drug repositioning techniques to extend the lifespan and applications of existing drugs as well as maximize the return on investment in drug research and development.

Drugs and the Liver

Author : Penny North-Lewis
Publisher : Unknown
Page : 348 pages
File Size : 49,5 Mb
Release : 2008
Category : Medical
ISBN : UOM:39015073936794

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Drugs and the Liver by Penny North-Lewis Pdf

This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions. It will be invaluable to clinical pharmacists and anyone making medicine choices in patients with liver impairment.

Drugs, Ethics, and Quality of Life

Author : Bruce White
Publisher : CRC Press
Page : 352 pages
File Size : 46,7 Mb
Release : 2021-10-12
Category : Business & Economics
ISBN : 9781000572551

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Drugs, Ethics, and Quality of Life by Bruce White Pdf

Weigh pivotal healthcare ethics, law, and public policy issues that resulted in tipping-point legal actions Weighing the ethical considerations in healthcare and drug issues can be emotionally difficult and mentally challenging. Drugs, Ethics, and Quality of Life: Cases and Materials on Ethical, Legal, and Public Policy Dilemmas in Medicine and Pharmacy Practice is a fascinating casebook that clearly discusses the most contentious ethical conflicts that resulted in legal actions. This easy-to-read text provides all sides of controversial real-life cases that provoke spirited debate while teaching the fundamentals of pharmacy law and ethics. The book is a unique exploration into the basic principles of bioethics, end of life care, and drug research. Drugs, Ethics, and Quality of Life explains in detail the concepts of ethics, quality of life, beneficence, nonmaleficence, autonomy, and justice. Recent cases provide illuminating backdrops for the exploration of these concepts, making them easily understood. A special introduction includes important information about ethics and the pharmaceutical code of ethics. Two appendixes provide further opportunities for discussion and the examination of law and decisions, and resources about drug use decisions and situations. This thought-provoking textbook plainly shows the crucial role ethics plays in today’s society. Ethical topics explored in Drugs, Ethics, and Quality of Life includes legal cases on: tobacco COX-2 inhibitors medical marijuana the “morning after” pill and other emergency contraceptives pain medications and palliative care drugs physician-assisted suicide drug use in medically futile situations gene therapy Drugs, Ethics, and Quality of Life is valuable, insightful reading as well as a good adjunct text for pharmacy students, pharmacists, medical students, physicians, bio

Life-Threatening Effects of Antipsychotic Drugs

Author : Peter Manu,Robert J. Flanagan,Kathlyn J. Ronaldson
Publisher : Academic Press
Page : 394 pages
File Size : 43,5 Mb
Release : 2016-08-16
Category : Medical
ISBN : 9780128033906

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Life-Threatening Effects of Antipsychotic Drugs by Peter Manu,Robert J. Flanagan,Kathlyn J. Ronaldson Pdf

Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations

The Life-Cycle of Pharmaceuticals in the Environment

Author : B.M. Peake,R. Braund,Alfred Tong,Louis A Tremblay
Publisher : Elsevier
Page : 272 pages
File Size : 41,7 Mb
Release : 2015-11-13
Category : Medical
ISBN : 9781908818454

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The Life-Cycle of Pharmaceuticals in the Environment by B.M. Peake,R. Braund,Alfred Tong,Louis A Tremblay Pdf

The Life-Cycle of Pharmaceuticals in the Environment identifies pathways of entry of pharmaceuticals into the environment, beginning with the role of global prescribing and disposal practices. The book then discusses typical levels of common pharmaceuticals and how they can be determined in natural waters such as raw and treated sewage, and in potable water. In addition, sections examine methods currently available to degrade pharmaceuticals in natural waters and some of their ecotoxicological impacts, along with future considerations and the growing concept of product stewardship. Encompasses the full lifecycle of common pharmaceuticals, from prescription and dispensing practices to their occurrence in a range of different types of natural waters and their environmental impact Explores the role of the healthcare system and its affect on users Beneficial for environmental engineers involved in the design and operation of appropriate degradation technologies of the pharmaceutical prescription and disposal practices

Sex, Drugs, Ratt & Roll

Author : Stephen Pearcy,Sam Benjamin
Publisher : Simon and Schuster
Page : 320 pages
File Size : 53,6 Mb
Release : 2014-04-15
Category : Biography & Autobiography
ISBN : 9781451694581

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Sex, Drugs, Ratt & Roll by Stephen Pearcy,Sam Benjamin Pdf

A tell-all memoir from the lead singer of the 1980s hair-metal band Ratt reveals all the aspects of rock star excess, including the groupies, the trashed hotel rooms, and the drugs.

The $800 Million Pill

Author : Merrill Goozner
Publisher : Univ of California Press
Page : 308 pages
File Size : 47,8 Mb
Release : 2005-10-10
Category : Medical
ISBN : 0520246705

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The $800 Million Pill by Merrill Goozner Pdf

"Goozner shows how drug innovation is driven by dedicated scientists intent on finding cures for diseases, not by pharmaceutical firms, whose bottom line often takes precedence over the advance of medicine. Stories of a university biochemist who spent twenty years searching for single blood protein that later became the best-selling biotech drug in the world, a government employee who discovered the causes for dozens of crippling genetic disorders, and the Department of Energy-funded research that made the Human Genome Project possible - these accounts illustrate how medical breakthroughs actually take place.".

Memoirs of an Addicted Brain

Author : Marc Lewis
Publisher : Doubleday Canada
Page : 313 pages
File Size : 46,7 Mb
Release : 2011-10-04
Category : Biography & Autobiography
ISBN : 9780385669269

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Memoirs of an Addicted Brain by Marc Lewis Pdf

A gripping, ultimately triumphant memoir that's also the most comprehensive and comprehensible study of the neuroscience of addiction written for the general public. FROM THE INTRODUCTION: "We are prone to a cycle of craving what we don't have, finding it, using it up or losing it, and then craving it all the more. This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?" The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception. Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

The Colonial Life of Pharmaceuticals

Author : Laurence Monnais
Publisher : Cambridge University Press
Page : 291 pages
File Size : 45,7 Mb
Release : 2019-08-22
Category : History
ISBN : 9781108474665

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The Colonial Life of Pharmaceuticals by Laurence Monnais Pdf

Innovative examination of the early globalization of the pharmaceutical industry, arguing that colonialism was crucial to the worldwide diffusion of modern medicines.

Pharmaceutical Biotechnology

Author : Gary Walsh
Publisher : John Wiley & Sons
Page : 504 pages
File Size : 52,6 Mb
Release : 2013-04-25
Category : Science
ISBN : 9781118685754

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Pharmaceutical Biotechnology by Gary Walsh Pdf

Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Life After You

Author : Linda Lajterman
Publisher : Unknown
Page : 128 pages
File Size : 41,9 Mb
Release : 2014-09-15
Category : Electronic
ISBN : 0990634302

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Life After You by Linda Lajterman Pdf

Writing by a mother whose son died from a drug overdose, this book is a cautionary tale to teens about the devastation they leave behind after a death from drugs.

Bad Pharma

Author : Ben Goldacre
Publisher : Signal
Page : 304 pages
File Size : 54,5 Mb
Release : 2013-02-05
Category : Medical
ISBN : 9780771036316

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Bad Pharma by Ben Goldacre Pdf

We all feel uncomfortable about the role of profit in healthcare, we all have a vague notion that the global $600bn pharmaceutical industry is somehow evil and untrustworthy, but that sense rarely goes beyond a flaky, undifferentiated new age worldview. Bad Pharma puts real flesh on those bones, revealing the rigged evidence used by drug companies. Bad information means bad treatment decisions, which means patients suffer and die: there is no climactic moment of villainy, but drugs are used which are overpriced, less effective, and have more side effects. There are five cheap, easy things we can do to fix the problem. Bad Pharma takes a big dirty secret out into the open, and will provide a single focus for concerns people have both inside and outside medicine.

Drugs and Life

Author : Harry H. Avis
Publisher : Unknown
Page : 128 pages
File Size : 41,6 Mb
Release : 1999-01-01
Category : Electronic
ISBN : 0072319755

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Drugs and Life by Harry H. Avis Pdf