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Membrane Bioenergetics by Vladimir P. Skulachev Pdf
Membrane bioenergetics is one of the most rapidly growing areas within physico-chemical biology. Main aspects treated in this book include energy conservation and utilization by membrane-linked molecular mechanisms such as intracellular respiration, photosynthesis, transport phenomena, rotation of bacterial flagella, and the regulation of heat production.
Bioenergetics by David G. Nicholls,Stuart J. Ferguson Pdf
This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available. Key Features * Chapter on the study of bioenergetics of mitochondria in the intact cell * Appendix listing protein structure resources * Additional colour plates of protein structures * Many newly drawn illustrations * Website
Bioenergetics 2 by David G. Nicholls,Stuart J. Ferguson Pdf
Bioenergetics 2 aims to clarify topics such as the thermodynamics of bioenergetic processes and the stoichiometries of energy coupling reactions. The book discusses chemiosmotic energy transduction; ion transport across energy-conserving membranes; and quantitative bioenergenetics as the measurement of driving forces. The text also describes the chemiosmotic proton circuit; the respiratory chain; the photosynthetic generators of protonmotive force; and the ATP synthase. The secondary transport of products across the membrane, as well as the structures of the bacterial photosynthetic reaction center and bacteriorhodopsin are also considered. Biochemists will find the book invaluable.
Energy Transduction in Biological Membranes by William A. Cramer,David B. Knaff Pdf
Energy Transduction in Biological Membranes was primarily designed for graduate courses in bioenergetics. Not only does it discuss basic principles and concepts central to modern membrane biochemistry, biophysics and molecular biology, but also (1) the components and pathways for electron transport and hydrogen ion translocation, and (2) the utilization of electrochemical ion gradients. The book is unique in presenting a comparative treatment of respiratory and photosynthetic energy transduction, and in using protein sequence data coupled with physical concepts to discuss the mechanisms of energy transducing proteins.
Advances in Membrane Biochemistry and Bioenergetics by Chong H. Kim,Henry Tedeschi,Joyce J. Diwan,John C. Salerno Pdf
This book is formulated from the papers presented at the International Symposium on "Membrane Biochemistry and Bioenergetics," held at the Rensselaerville Institute, Rensselaerville, New York, August 1986, in honor of Tsoo E. King on the occasion of the 30th anniversary of reconstitution of arespiratory chain system by Professor David Keilin and Tsoo E. King. Professor Tsoo E. King, to whom this volume is dedicated, has made enormous contributions to the field of isolation and reconstitution of membrane proteins and has continued to explore the frontiers of bioener getics. In particular, his persistent proposals on the existence of ubiquinone binding proteins from conceptualization to experimentation eventually convinced many scientists to study these proteins further . Professor King's preparation of reconstitutively active succinate dehydrogenase opened a new avenue in the fie1d of membrane bioenergetics, and his work has been greatly appreciated. The purpose of the symposium was to bring together scientists from diverse disciplines related to membrane bioenergetics to discuss the recent developments in the field. This symposium, initiated by the Capital District Bioenergetics Group, was attended by 100 scientists, 80 of whom presented their recent discoveries. The symposium was arranged in a sequence of platform lectures, poster presentations and discussion sessions so that all the participants had opportunities to discuss the subjects presented. Most of the participants contributed a chapter to this volume. We would like to express our regret to many other scientists including Professor King's friends, colleagues and students who could not attend due to various reasons.
Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology. Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins. Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging. Offers readers clear, visual representation of structural concepts through full colour figures throughout the book.
Membrane Biochemistry by E. Carafoli,G. Semenza Pdf
This manual collects in the form of laboratory protocols a series of experiments in the field of Membrane Transport and Membrane Bioenergetics. It represents the experience accumulated during four advanced courses held at the Depart ment of Biochemistry of the Swiss Federal Institute of Technology on behalf of Federation of European Biochemical Societies (FEBS) in the years 1975 through 1978. The idea of collecting the experiments into a laboratory manual developed as a response to a demand from the students who took part in the courses. Further motivation came with the fmding that, in planning the laboratory sessions, the teaching staff had no organized, modern source of information in the literature. The experiments presented cover most areas of importance in the subject mat ter. Their presentation has been continuously modified in the course of the four years during which the manual took shape, to accommodate to experience and various suggestions. In their present form, all of the experiments described have been repeatedly practiced to optimize their execution. Efforts have been made to combine in the manual classical experiments, and techniques which require relatively unsophisticated instrumentation and can therefore be carried out in most laboratories, with more modern experiments and relatively newer technol ogies. In its present form, the manual should therefore provide a usefui tool in the hands of researchers and laboratory teachers at different levels of sophisti cation and instrumentation.
Bioenergetics deals with the very first energy transformation steps performed by living cells. Increased dissipation is the primary effect of processing external energy packages. Enzyme-supported charge separation is the minor but essential outcome for maintaining life. This book explores the usefulness of dissecting the entropy production of enzymes involved in cellular defenses, fermentation, respiration, and photosynthesis, assuming that tightly regulated dissipation is the hallmark of life. Researchers, educators, and students of life sciences can find in this text many examples of how we can use the interdisciplinary approach to study cells' virtuoso ability to connect the microscopic to the macroscopic world. Each chapter is a self-contained unit with a glossary and selected references for further reading.
Bioenergetics 3 by David G. Nicholls,Stuart John Ferguson Pdf
Revised and updated to include the many developments that have taken place in bioenergetics, this text covers the structures of key membrane proteins involved in bioenergetics and mitochondrial physiology.
Vladimir P. Skulachev,Alexander V. Bogachev,Felix O. Kasparinsky
Author : Vladimir P. Skulachev,Alexander V. Bogachev,Felix O. Kasparinsky Publisher : Springer Science & Business Media Page : 435 pages File Size : 51,8 Mb Release : 2012-12-15 Category : Science ISBN : 9783642334306
Principles of Bioenergetics by Vladimir P. Skulachev,Alexander V. Bogachev,Felix O. Kasparinsky Pdf
Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.
This book describes a half century of research on cellular membrane transport and on metabolic energy capture and utilization. During this time-which begins in the late 1930s-the effort and imagination of various scientists overthrew reigning formulations, created novel explanatory models, and unified previously distinct experimental fields. My primary goal is to display the course of that research, showing how new experiments defined novel entities and processes, and how an encompassing field, bioenergetics, then emerged. A secondary goal is to present examples of mainstream biological research that illustrate how experimental results-seen as refutations, confirmations, and elabora tions-can sway opinion toward a solid consensus. This interpretation differs from the currently fashionable view of some commentators that stresses instead the central roles of power, prestige, gender, class, and ethnicity. In any case, the scien tific practices exhibited here deserve proper philosophical scrutiny. Although con straints of space have squeezed any analysis from this draft, brief mention of salient issues does appear in relevant chapters and in the final conclusions. (Oddly, histori ans and philosophers seem reluctant to deal with this science. Those who do consider biological topics tend to focus on the theory of evolution, even though the bulk of biological research in this century, in terms of papers published and technology influenced, has dealt not with evolution per se but with what may be termed physiology and biochemistry. And these endeavors, which are the aims, efforts, and accomplishments of the vast majority of biologists, have been largely ignored.
Mechanisms of Primary Energy Transduction in Biology by Mårten Wikström Pdf
This book describes the events of primary energy transduction in life processes. Life as we know it depends on pumping protons across membranes. New tools to study the protein complexes involved has led to recent intensified progress in the field. Primary Energy Transduction in Biology focusses on recent structural results and new biophysical insights. These have been made possible by recent advances in high-resolution protein structures, in physical techniques to study reactions in real time, and in computational methods to study and refine both structures and their dynamics. Written and edited by leading experts, chapters discuss the latest key questions in cell respiration, photosynthesis, bioenergetics, proton transfer, electron transfer and membrane transport. Biochemists, biophysicists and chemical biologists will find this book an essential resource for a complete understanding of the molecular machines of bioenergetics.
Membrane Structure and Mechanisms of Biological Energy Transduction by J. Avery Pdf
The problem of electron transfer phosphorylation was first formu lated in 1939 by Belitser and Tsibakova I who introduced the "P: 0" criterion and showed that this ratio is more than 1. The authors noted that such a high value of the phosphorylation coefficient suggests a fundamental difference in the mechanisms of A TP formation coupled with respiration, and glycolysis, since in the latter case, the amount of the ATP synthesized is equal to that of the substrate utilized. A lot of hypothetical schemes were put forward to explain the nature of coupling between electron transfer and phosphorylation, but none of them solved the problem. Only quite recently, one hypo thetical scheme of energy coupling, viz. Mitchell's chemiosmotic concept, 2.3 was supported by experimental data which allow us to prefer it to alternative possibilities. In this paper, I shall try to substantiate the statement that oxidation and phosphorylation can be coupled via a membrane potential as was postulated by Mitchell.
