Molecular Evolution

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Integrated Molecular Evolution

Scott Orland Rogers
Integrated Molecular Evolution Book PDF

Author : Scott Orland Rogers
Publisher : CRC Press
Page : 574 pages
File Size : 50,7 Mb
Release : 2016-06-08
Category : Science
ISBN : 9781482230901

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Integrated Molecular Evolution by Scott Orland Rogers Pdf

Evolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics. Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Cancer Extraction of biological molecules Analytical methods Sequencing methods and sequencing analyses Omics Phylogenetics and phylogenetic networks Protein trafficking Human genomics More than 400 illustrations appear in this edition, doubling the number included in the first edition, and over 100 of these diagrams are now in color. The second edition combines and integrates extensive summaries of genetics and evolutionary biology in a manner that is accessible for students at either the graduate or undergraduate level. It also provides both the basic foundations of molecular evolution, such as the structure and function of DNA, RNA and proteins, as well as more advanced chapters reviewing analytical techniques for obtaining sequences, and interpreting and archiving molecular and genomic data.

Fundamentals of Molecular Evolution

Dan Graur,Wen-Hsiung Li
Fundamentals of Molecular Evolution Book PDF

Author : Dan Graur,Wen-Hsiung Li
Publisher : Sinauer Associates Incorporated
Page : 481 pages
File Size : 40,7 Mb
Release : 2000-01
Category : Medical
ISBN : 0878932666

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Fundamentals of Molecular Evolution by Dan Graur,Wen-Hsiung Li Pdf

Genes, genetic codes, and mutation. Dynamics of genes in populations. Evolutionary change in nucleotide sequences. Rates and patterns of nucleotide substitution. Molecular phylogenetics. Gene duplication, exon shuffling, and concerted evolution. Evolution by transposition. Genome evolution. Spatial and temporal frameworks of the evolutionary process. Basics of probability.

The Causes of Molecular Evolution

John H. Gillespie
The Causes of Molecular Evolution Book PDF

Author : John H. Gillespie
Publisher : Oxford University Press
Page : 351 pages
File Size : 45,9 Mb
Release : 1994-05-26
Category : Science
ISBN : 9780195357745

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The Causes of Molecular Evolution by John H. Gillespie Pdf

This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.

Computational Molecular Evolution

Ziheng Yang
Computational Molecular Evolution Book PDF

Author : Ziheng Yang
Publisher : Oxford University Press
Page : 374 pages
File Size : 43,9 Mb
Release : 2006-10-05
Category : Medical
ISBN : 9780198566991

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Computational Molecular Evolution by Ziheng Yang Pdf

This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes.

Molecular Evolution

Roderick D.M. Page,Edward C. Holmes
Molecular Evolution Book PDF

Author : Roderick D.M. Page,Edward C. Holmes
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 52,7 Mb
Release : 2009-07-14
Category : Science
ISBN : 9781444313369

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Molecular Evolution by Roderick D.M. Page,Edward C. Holmes Pdf

The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Molecular Evolution

Ziheng Yang
Molecular Evolution Book PDF

Author : Ziheng Yang
Publisher : Oxford University Press
Page : 509 pages
File Size : 45,5 Mb
Release : 2014
Category : Science
ISBN : 9780199602605

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Molecular Evolution by Ziheng Yang Pdf

This book presents and explains modern statistical methods and computational algorithms for the comparative analysis of genetic sequence data in the fields of molecular evolution, molecular phylogenetics, statistical phylogeography, and comparative genomics. The book offers numerous examples of real data analysis and numerical calculations to illustrate the theory, in addition to the working problems at the end of each chapter. The coverage of maximum likelihood and Bayesian methods are in particular up-to-date, comprehensive, and authoritative.

Bioinformatics and Molecular Evolution

Paul G. Higgs,Teresa K. Attwood
Bioinformatics and Molecular Evolution Book PDF

Author : Paul G. Higgs,Teresa K. Attwood
Publisher : John Wiley & Sons
Page : 384 pages
File Size : 52,8 Mb
Release : 2013-04-30
Category : Science
ISBN : 9781118697061

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Bioinformatics and Molecular Evolution by Paul G. Higgs,Teresa K. Attwood Pdf

In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology. This accessible text: provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM). This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.

Molecular Evolution and Phylogenetics

Masatoshi Nei,Sudhir Kumar
Molecular Evolution and Phylogenetics Book PDF

Author : Masatoshi Nei,Sudhir Kumar
Publisher : Oxford University Press
Page : 352 pages
File Size : 53,6 Mb
Release : 2000-07-27
Category : Science
ISBN : 9780199881222

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Molecular Evolution and Phylogenetics by Masatoshi Nei,Sudhir Kumar Pdf

During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Molecular and Genome Evolution

Dan Graur
Molecular and Genome Evolution Book PDF

Author : Dan Graur
Publisher : Sinauer
Page : 0 pages
File Size : 40,6 Mb
Release : 2015-01-01
Category : Science
ISBN : 1605354694

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Molecular and Genome Evolution by Dan Graur Pdf

This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.

The Neutral Theory of Molecular Evolution

Motoo Kimura
The Neutral Theory of Molecular Evolution Book PDF

Author : Motoo Kimura
Publisher : Cambridge University Press
Page : 388 pages
File Size : 51,9 Mb
Release : 1983
Category : Science
ISBN : 0521317932

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The Neutral Theory of Molecular Evolution by Motoo Kimura Pdf

This book is the first comprehensive treatment of this subject.

Statistical Methods in Molecular Evolution

Rasmus Nielsen
Statistical Methods in Molecular Evolution Book PDF

Author : Rasmus Nielsen
Publisher : Springer Science & Business Media
Page : 503 pages
File Size : 44,5 Mb
Release : 2006-05-06
Category : Science
ISBN : 9780387277332

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Statistical Methods in Molecular Evolution by Rasmus Nielsen Pdf

In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in molecular evolution rely heavily on statistical procedures based on stochastic process modelling and advanced computational methods including high-dimensional numerical optimization and Markov Chain Monte Carlo. This book provides an overview of the statistical theory and methods used in studies of molecular evolution. It includes an introductory section suitable for readers that are new to the field, a section discussing practical methods for data analysis, and more specialized sections discussing specific models and addressing statistical issues relating to estimation and model choice. The chapters are written by the leaders of field and they will take the reader from basic introductory material to the state-of-the-art statistical methods. This book is suitable for statisticians seeking to learn more about applications in molecular evolution and molecular evolutionary biologists with an interest in learning more about the theory behind the statistical methods applied in the field. The chapters of the book assume no advanced mathematical skills beyond basic calculus, although familiarity with basic probability theory will help the reader. Most relevant statistical concepts are introduced in the book in the context of their application in molecular evolution, and the book should be accessible for most biology graduate students with an interest in quantitative methods and theory. Rasmus Nielsen received his Ph.D. form the University of California at Berkeley in 1998 and after a postdoc at Harvard University, he assumed a faculty position in Statistical Genomics at Cornell University. He is currently an Ole Rømer Fellow at the University of Copenhagen and holds a Sloan Research Fellowship. His is an associate editor of the Journal of Molecular Evolution and has published more than fifty original papers in peer-reviewed journals on the topic of this book. From the reviews: "...Overall this is a very useful book in an area of increasing importance." Journal of the Royal Statistical Society "I find Statistical Methods in Molecular Evolution very interesting and useful. It delves into problems that were considered very difficult just several years ago...the book is likely to stimulate the interest of statisticians that are unaware of this exciting field of applications. It is my hope that it will also help the 'wet lab' molecular evolutionist to better understand mathematical and statistical methods." Marek Kimmel for the Journal of the American Statistical Association, September 2006 "Who should read this book? We suggest that anyone who deals with molecular data (who does not?) and anyone who asks evolutionary questions (who should not?) ought to consult the relevant chapters in this book." Dan Graur and Dror Berel for Biometrics, September 2006 "Coalescence theory facilitates the merger of population genetics theory with phylogenetic approaches, but still, there are mostly two camps: phylogeneticists and population geneticists. Only a few people are moving freely between them. Rasmus Nielsen is certainly one of these researchers, and his work so far has merged many population genetic and phylogenetic aspects of biological research under the umbrella of molecular evolution. Although Nielsen did not contribute a chapter to his book, his work permeates all its chapters. This book gives an overview of his interests and current achievements in molecular evolution. In short, this book should be on your bookshelf." Peter Beerli for Evolution, 60(2), 2006

The Evolution of Molecular Biology

Kensal Van Holde,Jordanka Zlatanova
The Evolution of Molecular Biology Book PDF

Author : Kensal Van Holde,Jordanka Zlatanova
Publisher : Academic Press
Page : 242 pages
File Size : 47,7 Mb
Release : 2018-02-20
Category : Science
ISBN : 9780128129180

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The Evolution of Molecular Biology by Kensal Van Holde,Jordanka Zlatanova Pdf

The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances–and an individual’s own research–have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery. Expands on the development of molecular biology from the convergence of two independent disciplines, biochemistry and genetics Discusses the value of molecular biology in a variety of applications Includes research ethics and the societal implications of research Emphasizes the human aspects of research and the consequences of such advances to society

The Molecular Evolutionary Clock

Simon Y. W. Ho
The Molecular Evolutionary Clock Book PDF

Author : Simon Y. W. Ho
Publisher : Springer Nature
Page : 245 pages
File Size : 41,9 Mb
Release : 2021-01-18
Category : Science
ISBN : 9783030601812

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The Molecular Evolutionary Clock by Simon Y. W. Ho Pdf

This book presents coverage of the principles and practice of molecular clocks, which have provided fascinating and unprecedented insights into the evolutionary timescale of life on earth. It begins by following the early development of the molecular evolutionary clock in the 1960s, and leads to the complex statistical approaches that are now used to analyse genome sequences. The chapters of this book have been contributed by leading experts in the field and address the important issues of evolutionary rates, molecular dating, and phylogenomic analysis. This is the first time that these different aspects of the molecular clock have been brought together in a single, comprehensive volume. It is an invaluable reference for students and researchers interested in evolutionary biology, genetic analysis, and genomic evolution.

Molecular Markers, Natural History and Evolution

J. C. Avise
Molecular Markers Natural History and Evolution Book PDF

Author : J. C. Avise
Publisher : Springer Science & Business Media
Page : 522 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461523819

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Molecular Markers, Natural History and Evolution by J. C. Avise Pdf

Molecular approaches have opened new windows on a host of ecological and evolutionary disciplines, ranging from population genetics and behavioral ecology to conservation biology and systematics. Molecular Markers, Natural History and Evolution summarizes the multi-faceted discoveries about organisms in nature that have stemmed from analyses of genetic markers provided by polymorphic proteins and DNAs. The first part of the book introduces rationales for the use of molecular markers, provides a history of molecular phylogenetics, and describes a wide variety of laboratory methods and interpretative tools in the field. The second and major portion of the book provides a cornucopia of biological applications for molecular markers, organized along a scale from micro-evolutionary topics (such as forensics, parentage, kinship, population structure, and intra-specific phylogeny) to macro-evolutionary themes (including species relationships and the deeper phylogenetic structure in the tree of life). Unlike most prior books in molecular evolution, the focus is on organismal natural history and evolution, with the macromolecules being the means rather than the ends of scientific inquiry. Written as an intellectual stimulus for the advanced undergraduate, graduate student, or the practicing biologist desiring a wellspring of research ideas at the interface of molecular and organismal biology, this book presents material in a manner that is both technically straightforward, yet rich with concepts and with empirical examples from the world of nature.

Fundamentals of Molecular Evolution

Wen-Hsiung Li,Dan Graur
Fundamentals of Molecular Evolution Book PDF

Author : Wen-Hsiung Li,Dan Graur
Publisher : Sinauer Associates, Incorporated
Page : 308 pages
File Size : 43,5 Mb
Release : 1991
Category : Science
ISBN : MINN:31951D01933158O

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Fundamentals of Molecular Evolution by Wen-Hsiung Li,Dan Graur Pdf

An introductory text which strives to maintain the standards of the scientific method and to include quantitative treatments of the issues. Knowledge of molecular biology, evolution, and math is not prerequisite. Annotation copyrighted by Book News, Inc., Portland, OR