Non Canonical Autophagy

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Non-Canonical Autophagy

Author : Giulia Petroni,Lorenzo Galluzzi
Publisher : Academic Press
Page : 184 pages
File Size : 47,9 Mb
Release : 2021-04-21
Category : Science
ISBN : 9780128209110

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Non-Canonical Autophagy by Giulia Petroni,Lorenzo Galluzzi Pdf

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

Membrane Biogenesis

Author : Jos A.F. Op den Kamp
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 48,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783642731846

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Membrane Biogenesis by Jos A.F. Op den Kamp Pdf

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Autophagy in Health and Disease

Author : Roberta A. Gottlieb
Publisher : Academic Press
Page : 241 pages
File Size : 45,5 Mb
Release : 2012-10-16
Category : Medical
ISBN : 9780123851017

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Autophagy in Health and Disease by Roberta A. Gottlieb Pdf

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes

Autophagy in Autoimmunity

Author : Xu-jie Zhou,Panayotis Verginis,Jennifer Martinez,Marko Radic
Publisher : Frontiers Media SA
Page : 161 pages
File Size : 50,6 Mb
Release : 2019-05-15
Category : Electronic
ISBN : 9782889458127

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Autophagy in Autoimmunity by Xu-jie Zhou,Panayotis Verginis,Jennifer Martinez,Marko Radic Pdf

Autophagy of the Nervous System

Author : Zhenyu Yue,Charleen T. Chu
Publisher : World Scientific
Page : 441 pages
File Size : 43,6 Mb
Release : 2012
Category : SCIENCE
ISBN : 9789814350440

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Autophagy of the Nervous System by Zhenyu Yue,Charleen T. Chu Pdf

What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy.

The Role of Autophagy in Infectious Diseases

Author : Hua Niu,Meihong Deng
Publisher : Frontiers Media SA
Page : 183 pages
File Size : 47,6 Mb
Release : 2022-11-08
Category : Science
ISBN : 9782832504260

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The Role of Autophagy in Infectious Diseases by Hua Niu,Meihong Deng Pdf

A year in review: Discussions in autoimmune and autoinflammatory disorders

Author : Raphaela Goldbach-Mansky,Betty Diamond
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 48,5 Mb
Release : 2023-03-31
Category : Medical
ISBN : 9782832519387

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A year in review: Discussions in autoimmune and autoinflammatory disorders by Raphaela Goldbach-Mansky,Betty Diamond Pdf

Transport Proteins

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 54,8 Mb
Release : 2021-01-21
Category : Science
ISBN : 9780128220887

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Transport Proteins by Anonim Pdf

Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more. Integrates experimental and computational methods for studying the structure and function of transport proteins and their implication in drug design Contains timely chapters written by well-renowned authorities in their field Includes a high number of top quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

Programmed Cell Death 2.0: The Quality of Cell Death

Author : Michael Thomas Lotze,Yinan Gong,Jennifer Martinez,Na Dong
Publisher : Frontiers Media SA
Page : 156 pages
File Size : 41,6 Mb
Release : 2022-02-14
Category : Science
ISBN : 9782889743902

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Programmed Cell Death 2.0: The Quality of Cell Death by Michael Thomas Lotze,Yinan Gong,Jennifer Martinez,Na Dong Pdf

Plant Cell Membranes

Author : Lester Packer,Roland Douce
Publisher : Academic Press
Page : 806 pages
File Size : 53,6 Mb
Release : 1987-11-28
Category : Nature
ISBN : UCSD:31822033947557

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Plant Cell Membranes by Lester Packer,Roland Douce Pdf

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.

New insights into innate immune cell-based immunotherapies in cancer

Author : Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 54,7 Mb
Release : 2024-04-17
Category : Medical
ISBN : 9782832548042

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New insights into innate immune cell-based immunotherapies in cancer by Mary Poupot-Marsan,Anne Caignard,Daniela Wesch,Virginie Lafont,Chiara Porta Pdf

The Autophagy Pathway: Bacterial Pathogen Immunity and Evasion

Author : Chinnaswamy Jagannath,Jere W. McBride,Isabelle Vergne
Publisher : Frontiers Media SA
Page : 155 pages
File Size : 45,9 Mb
Release : 2021-11-25
Category : Science
ISBN : 9782889716852

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The Autophagy Pathway: Bacterial Pathogen Immunity and Evasion by Chinnaswamy Jagannath,Jere W. McBride,Isabelle Vergne Pdf

Protein Phosphorylation in Human Health

Author : Cai Huang
Publisher : BoD – Books on Demand
Page : 482 pages
File Size : 51,5 Mb
Release : 2012-09-06
Category : Medical
ISBN : 9789535107378

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Protein Phosphorylation in Human Health by Cai Huang Pdf

15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.