Overdose

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Overdose

Author : Benjamin Perrin
Publisher : Penguin
Page : 0 pages
File Size : 55,7 Mb
Release : 2022-01-04
Category : Health & Fitness
ISBN : 9780735237889

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Overdose by Benjamin Perrin Pdf

NATIONAL BESTSELLER SHORTLISTED for the 2021 BC Book Awards' George Ryga Award for Social Awareness in Literature SHORTLISTED for the BC and Yukon Book Prizes, for both the Hubert Evans Non-Fiction Prize and Jim Deva Prize for Writing That Provokes SHORTLISTED for the 2021 J. W. Dafoe Book Prize SHORTLISTED for the 2020 Lane Anderson Award “Overdose is a necessary and searching investigation into a devastating epidemic that should never have happened. Benjamin Perrin painstakingly shows that it need not continue if we, as a society, heed the evidence.” —Gabor Maté M.D., author of In The Realm of Hungry Ghosts: Close Encounters With Addiction An astonishing and powerful look at the ongoing opioid crisis North America is in the middle of a health emergency. Life expectancies are declining. Someone is dying every two hours in Canada from illicit drug overdose. Fentanyl has become a looming presence—an opioid more powerful, pervasive, and deadly than any previous street drug. The victims are many—and often not whom we might expect. They include the poor and forgotten but also our neighbours: professionals, students, and parents. Despite the thousands of deaths, these victims have remained largely invisible. But not anymore. Benjamin Perrin, a law and policy expert, shines a light in this darkest of corners—and his findings challenge many assumptions about the crisis. Why do people use drugs despite the risk of overdosing? Can we crack down on the fentanyl supply? Do supervised consumption sites and providing “safe drugs” enable the problem? Which treatments work? Would decriminalizing all drugs help or do further harm? In this urgent and humane look at a devastating epidemic, Perrin draws on behind-the-scenes interviews with those on the frontlines, including undercover police officers, intelligence analysts, border agents, prosecutors, healthcare professionals, Indigenous organizations, activists, and people who use drugs. Not only does he unveil the many complexities of this situation, but he also offers a new way forward—one that may save thousands of lives.

American Overdose

Author : Chris McGreal
Publisher : PublicAffairs
Page : 381 pages
File Size : 48,8 Mb
Release : 2018-11-13
Category : Social Science
ISBN : 9781541773776

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American Overdose by Chris McGreal Pdf

A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

Community Management of Opioid Overdose

Author : World Health Organization
Publisher : Unknown
Page : 0 pages
File Size : 40,8 Mb
Release : 2015-09-08
Category : Medical
ISBN : 9241548819

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Community Management of Opioid Overdose by World Health Organization Pdf

An estimated 69000 people die each year from opioid overdose. Opioid overdose is easily reversed with the opioid antidote naloxone and with basic life support. Such care is generally only available in medical settings, however. These guidelines recommend that people who are likely to witness an opioid overdose, including people who use opioids, and their family and friends should be given access to naloxone and training in its use so that they can respond to opioid overdose in an emergency if a medical response is not available. Naloxone can be injected or administered intra-nasally and has minimal effects in people who have not used opioids. While naloxone administered by bystanders is a potentially life-saving emergency interim response to opioid overdose, it should not be seen as a replacement for comprehensive medical care.

OD

Author : Nancy D. Campbell
Publisher : MIT Press
Page : 425 pages
File Size : 55,8 Mb
Release : 2020-03-03
Category : Medical
ISBN : 9780262357487

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OD by Nancy D. Campbell Pdf

The history of an unnatural disaster—drug overdose—and the emergence of naloxone as a social and technological solution. For years, drug overdose was unmentionable in polite society. OD was understood to be something that took place in dark alleys—an ugly death awaiting social deviants—neither scientifically nor clinically interesting. But over the last several years, overdose prevention has become the unlikely object of a social movement, powered by the miracle drug naloxone. In OD, Nancy Campbell charts the emergence of naloxone as a technological fix for overdose and describes the remaking of overdose into an experience recognized as common, predictable, patterned—and, above all, preventable. Naloxone, which made resuscitation, rescue, and “reversal” after an overdose possible, became a tool for shifting law, policy, clinical medicine, and science toward harm reduction. Liberated from emergency room protocols and distributed in take-home kits to non-medical professionals, it also became a tool of empowerment. After recounting the prehistory of naloxone—the early treatment of OD as a problem of poisoning, the development of nalorphine (naloxone's predecessor), the idea of “reanimatology”—Campbell describes how naloxone emerged as a tool of harm reduction. She reports on naloxone use in far-flung locations that include post-Thatcherite Britain, rural New Mexico, and cities and towns in Massachusetts. Drawing on interviews with approximately sixty advocates, drug users, former users, friends, families, witnesses, clinicians, and scientists—whom she calls the “protagonists” of her story—Campbell tells a story of saving lives amid the complex, difficult conditions of an unfolding unnatural disaster.

Paradise Overdose

Author : Brian Antoni,Robert Antoni
Publisher : Grove Press
Page : 260 pages
File Size : 41,5 Mb
Release : 1997
Category : Fiction
ISBN : 0802134874

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Paradise Overdose by Brian Antoni,Robert Antoni Pdf

The decadent chic of Bahamian high life collides with bittersweet romance in this poignant and powerful novel that explores the redemptive power of love. Chris Angostura, the scion of a prominent family, frolics away his days and nights drinking and clubhopping in the Bahamas, where sex and drugs are his for the taking. It is not until he meets Robin, a beautiful and exciting artist, that he begins to face his past in order to discover the true beauty behind the seductive façade of paradise.

Poisoning and Drug Overdose, Seventh Edition

Author : Kent R. Olson,Ilene B. Anderson,Neal L. Benowitz,Paul D. Blanc,Richard F. Clark,Thomas E. Kearney,Susan Y. Kim-Katz,Alan H. B. Wu
Publisher : McGraw Hill Professional
Page : 752 pages
File Size : 51,5 Mb
Release : 2017-12-15
Category : Medical
ISBN : 9780071839808

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Poisoning and Drug Overdose, Seventh Edition by Kent R. Olson,Ilene B. Anderson,Neal L. Benowitz,Paul D. Blanc,Richard F. Clark,Thomas E. Kearney,Susan Y. Kim-Katz,Alan H. B. Wu Pdf

The instant-answer guide clinicians turn to first for on-the-spot treatment of poisoning and drug overdose emergencies A Doody’s Core Title for 2019! “...a great addition to any emergency department library when rapid reference is needed to treat and diagnose the poisoned patient.” -- Annals of Emergency Medicine (Reviewing previous edition) Designed to be used during toxicologic emergencies where every moment counts, Poisoning & Drug Overdose, Seventh Edition delivers critical information on the effective diagnosis and treatment of drug-related emergencies and chemical exposures. This at-a-glance guide is enhanced by detailed tables and charts, extensive cross referencing, and a comprehensive index featuring generic, chemical, and brand names. Poisoning & Drug Overdose is divided into four sections: Section 1 leads readers through initial emergency management, including treatment of coma, hypotension, and other common complications; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons Section II provides detailed information on 150 common drugs and poisons Section III describes the use and side effects of 60 antidotes and therapeutic drugs Section IV describes the medical management of chemical spills and occupations chemical exposures and includes a table of more than 500 industrial chemicals • Thoroughly updated to reflect newly released drugs, new information on existing drugs, and coverage of the latest black box (and other) warnings • NEW to this edition: information on drug-environmental exposure interactions, coverage of environmental toxins such as mold, asbestos, and others

The Health Effects of Cannabis and Cannabinoids

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publisher : National Academies Press
Page : 487 pages
File Size : 43,7 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780309453073

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The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Overdosed America

Author : John Abramson
Publisher : Harper Collins
Page : 362 pages
File Size : 50,7 Mb
Release : 2005-06-14
Category : Business & Economics
ISBN : 9780060568535

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Overdosed America by John Abramson Pdf

Using the examples of Vioxx, Celebrex, cholesterol-lowering statin drugs, and anti-depressants, Overdo$ed America shows that at the heart of the current crisis in American medicine lies the commercialization of medical knowledge itself. Drawing on his background in statistics, epidemiology, and health policy, John Abramson, M.D., an award-winning family doctor on the clinical faculty at Harvard Medical School, reveals the ways in which the drug companies have misrepresented statistical evidence, misled doctors, and compromised our health. The good news is that the best scientific evidence shows that reclaiming responsibility for your own health is often far more effective than taking the latest blockbuster drug. You -- and your doctor -- will be stunned by this unflinching exposé of American medicine.

Addiction and Overdose

Author : Connie Goldsmith
Publisher : Twenty-First Century Books
Page : 132 pages
File Size : 51,5 Mb
Release : 2017
Category : Young Adult Nonfiction
ISBN : 9781512409536

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Addiction and Overdose by Connie Goldsmith Pdf

An exploration of drug addiction in the United States.

Overdose

Author : Richard Allen Epstein
Publisher : Yale University Press
Page : 295 pages
File Size : 47,8 Mb
Release : 2006-01-01
Category : Law
ISBN : 9780300116649

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Overdose by Richard Allen Epstein Pdf

This book is the first to offer a comprehensive examination of the pharmaceutical industry by following the tortuous course of a new drug as it progresses from early development to final delivery. Richard A. Epstein looks closely at the regulatory framework that surrounds all aspects of making pharmaceutical products today, and he assesses which current legal and regulatory practices make sense and which have gone awry. While critics of pharmaceutical companies call for ever more stringent controls on virtually every aspect of drug development and approval, Epstein cautions that the effect of such an approach will be to stifle pharmaceutical innovation and slow the delivery of beneficial treatments to the patients who need them. The author considers an array of challenges that confront the industry--conflicts of interest among government, academe, and the drug companies; intellectual property rights that govern patents; FDA regulation; pricing disputes; marketing practices; and liability issues, including those brought to light in the recent VIOXX case. Epstein argues that to ensure the continuing creativity, efficiency, and success of the pharmaceutical industry, the best system will feature strong property rights and clearly enforceable contracts, with minimal regulatory and judicial interference.

Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose

Author : Michael W. Shannon,Stephen W. Borron,Michael J. Burns (MD.),Lester M. Haddad,James F. Winchester
Publisher : Saunders
Page : 0 pages
File Size : 53,6 Mb
Release : 2007
Category : Drugs
ISBN : 0721606938

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Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose by Michael W. Shannon,Stephen W. Borron,Michael J. Burns (MD.),Lester M. Haddad,James F. Winchester Pdf

This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.

Overdose

Author : Benjamin Perrin
Publisher : Penguin
Page : 304 pages
File Size : 48,5 Mb
Release : 2020-03-31
Category : Health & Fitness
ISBN : 9780735237872

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Overdose by Benjamin Perrin Pdf

NATIONAL BESTSELLER SHORTLISTED for the 2021 BC Book Awards' George Ryga Award for Social Awareness in Literature SHORTLISTED for the BC and Yukon Book Prizes, for both the Hubert Evans Non-Fiction Prize and Jim Deva Prize for Writing That Provokes SHORTLISTED for the 2021 J. W. Dafoe Book Prize SHORTLISTED for the 2020 Lane Anderson Award “Overdose is a necessary and searching investigation into a devastating epidemic that should never have happened. Benjamin Perrin painstakingly shows that it need not continue if we, as a society, heed the evidence.” —Gabor Maté M.D., author of In The Realm of Hungry Ghosts: Close Encounters With Addiction An astonishing and powerful look at the ongoing opioid crisis North America is in the middle of a health emergency. Life expectancies are declining. Someone is dying every two hours in Canada from illicit drug overdose. Fentanyl has become a looming presence—an opioid more powerful, pervasive, and deadly than any previous street drug. The victims are many—and often not whom we might expect. They include the poor and forgotten but also our neighbours: professionals, students, and parents. Despite the thousands of deaths, these victims have remained largely invisible. But not anymore. Benjamin Perrin, a law and policy expert, shines a light in this darkest of corners—and his findings challenge many assumptions about the crisis. Why do people use drugs despite the risk of overdosing? Can we crack down on the fentanyl supply? Do supervised consumption sites and providing “safe drugs” enable the problem? Which treatments work? Would decriminalizing all drugs help or do further harm? In this urgent and humane look at a devastating epidemic, Perrin draws on behind-the-scenes interviews with those on the frontlines, including undercover police officers, intelligence analysts, border agents, prosecutors, healthcare professionals, Indigenous organizations, activists, and people who use drugs. Not only does he unveil the many complexities of this situation, but he also offers a new way forward—one that may save thousands of lives.

Drug-Induced Liver Injury

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 45,6 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

UNODC-WHO Stop-Overdose-Safely (S-O-S) project implementation in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine

Author : Anonim
Publisher : World Health Organization
Page : 42 pages
File Size : 52,7 Mb
Release : 2021-04-01
Category : Law
ISBN : 9789240022454

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UNODC-WHO Stop-Overdose-Safely (S-O-S) project implementation in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine by Anonim Pdf

This report details the main findings of the implementation of the WHO-UNODC Stop-Overdose-Safely (S-O-S) project in Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine. It provides an overview of the extent of the overdose problem and the development of responses, followed by a description of the methods used in implementation, monitoring and evaluation as measured through a prospective cohort study, focus groups, and qualitative interviews conducted in the four project countries. The S-O-S project resulted in the rapid distribution of take-home naloxone to 14,263 potential opioid overdose witnesses who were trained during the eight-month implementation phase. The cohort study found that 34.5% (out of 1388 study participants) witnessed an overdose during the implementation phase, and 90% of them reported using naloxone in cases of overdose. In almost all instances it was recorded that the victim survived (in 98.3% cases). Extrapolation of the naloxone use figures from the cohort study to the entire S-O-S project sample suggested that the implementation may have resulted in naloxone administration by as many as 4,388 individuals, with many lives saved as a result.

Addiction and Overdose

Author : Connie Goldsmith
Publisher : Twenty-First Century Books ™
Page : 128 pages
File Size : 49,9 Mb
Release : 2017-09-01
Category : Young Adult Nonfiction
ISBN : 9781512467789

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Addiction and Overdose by Connie Goldsmith Pdf

Drug overdosing and death from prescription painkillers and heroin are at epidemic levels in the United States. How do people become addicted to opioids and other dangerous drugs, and why? Meet the experts who study the neurology of addiction. Hear stories of addicts in recovery, and of loved ones left behind by those who died from overdosing. Discover more about the social and economic costs of overdosing and learn about scientific research to decrease it. Learn about the connection between addiction and mental health disorders. Find out how to identify signs of addiction and overdose and what you can do to help someone get assistance.