Pain Killer

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Pain Killer

Author : Barry Meier
Publisher : Random House
Page : 241 pages
File Size : 41,8 Mb
Release : 2018-05-29
Category : Medical
ISBN : 9780525511090

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Pain Killer by Barry Meier Pdf

From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.

Pain Killer

Author : Barry Meier
Publisher : Rodale
Page : 348 pages
File Size : 44,7 Mb
Release : 2003-10-17
Category : Medical
ISBN : 1579546382

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Pain Killer by Barry Meier Pdf

Examines OxyContin, the so-called miracle prescription drug that swept the nation but led to overdoes and addiction, providing a look at the multi-billion-dollar pain managment business, its excesses and its abuses.

Pain Killer

Author : Brantt Myhres
Publisher : Penguin
Page : 0 pages
File Size : 54,9 Mb
Release : 2022-04-26
Category : Biography & Autobiography
ISBN : 9780735239432

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Pain Killer by Brantt Myhres Pdf

#1 BESTSELLER "This book is at times startling, yet very real and down to earth . . . I saw [Brantt] in all phases of his life and his career. I consider him a friend and an ally. Pain Killer sends a strong message." --Darryl Sutter, former NHL player, coach, and GM From the only player to be banned for life from the NHL, a harrowing tale of addiction, and an astonishing path to recovery. Brantt Myhres wasn't around for the birth of his daughter. Myhres had played for seven different NHL teams, and had made millions. But he'd been suspended four times, all for drug use, and he had partied his way out of the league. By the time his daughter was born, he was penniless, sleeping on a friend's couch. He'd just been released from police custody. He had a choice between sticking around for the birth, or showing up for league-mandated rehab. He went to rehab. For the fifth time. This is his story, in his own words, of how he fought his way out of minor hockey into the big league, but never left behind the ghosts of a bleak and troubled childhood. He tells the story of discovering booze as a way of handling the anxiety of fighting, and of the thrill of cocaine. In the raw language of the locker room, he tells of how substance abuse poisoned the love he had in his life and sabotaged a great career. Full of stories of week-long benders, stripper-filled hot tubs, motorcycle crashes, and barroom brawls, Pain Killer is at its most powerful when Myhres acknowledges how he let himself down, and betrayed those who trusted him. Again and again, he fools the executives and doctors who gave him a second chance, then a third, then a fourth, and with each betrayal, he spirals further downward. But finally, on the eve of his daughter's birth, when all the money was gone, every bridge burnt, and every opportunity squandered, he was given a last chance. And this time, it worked. It worked so well, that not only has he been around for his daughter for the past eleven years, in 2015 he was signed by the LA Kings as a "sober coach": a guy who'd been there, a guy who could recognize and help solve problems before they ruined lives and made headlines (as the Kings had seen happen three times that season). Not only did Myhres save himself, he saved others. Unpolished, unpretentious, and unflinching, Myhres tells it like it is, acknowledging every mistake, and painting a portrait of an angry, violent, dangerous man caught in the vice of something he couldn't control, and didn't understand. If Brantt Myhres can pull himself together, anyone can. And he does, convincingly, and inspiringly.

Marijuana As Medicine?

Author : Institute of Medicine,Janet Joy,Alison Mack
Publisher : National Academies Press
Page : 216 pages
File Size : 45,7 Mb
Release : 2000-12-30
Category : Medical
ISBN : 9780309065313

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Marijuana As Medicine? by Institute of Medicine,Janet Joy,Alison Mack Pdf

Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Empire of Pain

Author : Patrick Radden Keefe
Publisher : Bond Street Books
Page : 480 pages
File Size : 52,7 Mb
Release : 2021-04-13
Category : Business & Economics
ISBN : 9780385697552

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Empire of Pain by Patrick Radden Keefe Pdf

A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin, by the prize-winning, bestselling author of Say Nothing The Sackler name adorns the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm. Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. The brothers began collecting art, and wives, and grand residences in exotic locales. Their children and grandchildren grew up in luxury. Forty years later, Raymond’s son Richard ran the family-owned Purdue. The template Arthur Sackler created to sell Valium—co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness—was employed to launch a far more potent product: OxyContin. The drug went on to generate some thirty-five billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die. This is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. It is a portrait of the excesses of America’s second Gilded Age, a study of impunity among the super elite and a relentless investigation of the naked greed and indifference to human suffering that built one of the world’s great fortunes.

Painkiller Addict

Author : Cathryn Kemp
Publisher : Piatkus
Page : 158 pages
File Size : 42,8 Mb
Release : 2012-09-06
Category : Biography & Autobiography
ISBN : 9781405515153

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Painkiller Addict by Cathryn Kemp Pdf

WINNER OF THE BIG RED READ PRIZE FOR NON-FICTION IN 2013. Cathryn Kemp was a successful travel journalist who was struck down by a life-threatening illness, pancreatitis. After four years of operations and mis-diagnoses she left hospital with a repeat prescription for fentanyl, a painkiller 100 times stronger than heroin. Within two years she was taking more than ten times the NHS maximum, all on prescription. Her family struggled to understand; her boyfriend left her, she hit rock bottom. Discovering she had only six months to live if she didn't give up the drugs she sold everything she owned and checked into rehab. In the addiction treatment centre she was told that she was unlikely to recover from 'the highest level of opiate-abuse in the clinic's history'. To everyone's amazement, she proved them wrong. This is an extraordinarily poignant, vivid and honest memoir. Based on the twenty-four diaries that the author kept during this period, we travel with Cathryn through her hospital agony, descend with her into the hell of addiction and cheer her as she pulls herself out and upwards. It is a love story, a horror story, a survival story, and one that shows only too clearly the very real dangers of the over-prescription of painkillers and tranquillisers. There is also a resource section for sufferers and their loved ones.

Acute Pain Medicine

Author : Chester C. Buckenmaier III,Michael Kent,Jason C. Brookman,Patrick J. Tighe,Edward R. Mariano,David Edwards
Publisher : Oxford University Press
Page : 672 pages
File Size : 40,9 Mb
Release : 2019-04-12
Category : Medical
ISBN : 9780190856663

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Acute Pain Medicine by Chester C. Buckenmaier III,Michael Kent,Jason C. Brookman,Patrick J. Tighe,Edward R. Mariano,David Edwards Pdf

Acute Pain Medicine is the first comprehensive, case-based text of its kind that explores the essential topics of acute pain medicine, including interventional, pharmacologic, and diagnostic considerations. Written and edited under the auspices of the American Academy of Pain Medicine by members of the Academy's Shared Interest Group for Acute Pain Medicine, the text includes an introduction to acute pain medicine and an easily referenced interventional section. Chapters focus on patients experiencing acute pain from either surgery or other medical conditions and include detailed information on the diagnosis and treatment of specific cases in acute pain medicine. The text is rounded out by the complete content of the thoroughly revised Military Advanced Regional Anesthesia and Analgesia Handbook (MARAA II). Although the MARAA handbook gained its reputation as a useful resource for managing the pain associated with battlefield trauma, its beautifully illustrated step-by-step guidance is useful for providing vital acute pain services in all settings. Acute Pain Medicine is an ideal, complete resource for physicians, fellows, and residents managing acute pain patients.

Pain Killer Marketing

Author : Chris Stiehl,Henry DeVries
Publisher : Academic Learning Company LLC
Page : 300 pages
File Size : 55,8 Mb
Release : 2008
Category : Business & Economics
ISBN : 0832950165

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Pain Killer Marketing by Chris Stiehl,Henry DeVries Pdf

Both business and customers feel pain when standards are not met. To kill this pain, a business must do more than conduct market research, it must know what to do with this information. Pain Killer Marketing presents effective methods for listening to and collecting customer pain. More importantly, it demonstrates how to implement data and drive profi ts. An excellent reference for C level executives, product managers, market research practitioners and those wanting to become more customer-centric . Anyone who has a suffering customer, internal or external, can benefit from Pain Killer Marketing.

Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Page : 483 pages
File Size : 50,8 Mb
Release : 2017-09-28
Category : Medical
ISBN : 9780309459570

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Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Drug-Induced Headache

Author : Hans-Christoph Diener,Marcia Wilkinson
Publisher : Springer Science & Business Media
Page : 174 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642733277

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Drug-Induced Headache by Hans-Christoph Diener,Marcia Wilkinson Pdf

M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Painkillers

Author : Victor B. Stolberg
Publisher : Bloomsbury Publishing USA
Page : 397 pages
File Size : 42,8 Mb
Release : 2016-03-14
Category : Health & Fitness
ISBN : 9798216126430

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Painkillers by Victor B. Stolberg Pdf

This accessible, easy-to-read book provides readers with different perspectives on the subject of painkillers, examining their history, production, uses, and dangers. Many different drugs are effectively used as painkillers—substances that greatly improve the quality of life for those who suffer from temporary or recurring pain. This book presents an in-depth overview of opiates, opioids, and other painkilling substances such as non-steroidal anti-inflammatory drugs (NSAIDs) that have been in use from ancient times up to the contemporary era. It also addresses the risks of painkiller use, their misuse, and potential overdose concerns. The latest in the Story of a Drug series and written by a subject expert who has published widely on drug use and pharmacology, this book presents a brief review of the science of how different painkiller drugs work before covering these substances' respective effects and applications; the issues regarding the production, distribution, and regulation of painkiller drugs; and research findings on painkiller use, abuse patterns, addiction, and policy issues. The easy-to-understand text presents scientifically accurate information that enables readers to better understand the key role of painkillers in our 21st-century world.

Magnesium in the Central Nervous System

Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 43,9 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051

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Magnesium in the Central Nervous System by Robert Vink,Mihai Nechifor Pdf

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Pill Head

Author : Joshua Lyon
Publisher : Hachette Books
Page : 238 pages
File Size : 51,6 Mb
Release : 2009-07-07
Category : Biography & Autobiography
ISBN : 9781401394493

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Pill Head by Joshua Lyon Pdf

This compelling, honest book investigates the growing epidemic of prescription painkiller abuse among today's Generation Rx. Through gripping profiles and heartbreaking confessions, this memoir dares to uncover the reality -- the addiction, the withdrawal, and the recovery -- of this newest generation of pill poppers. Joshua Lyon was no stranger to substance abuse. By the time he was seventeen, he had already found sanctuary in pot, cocaine, Ecstasy, and mushrooms -- just to name a few. Ten years later, on assignment for Jane magazine, he found himself with a two-inch-thick bottle of Vicodin in his hands and only one decision to make: dispose of the bottle or give in to his curiosity. He chose the latter. In a matter of weeks he'd found his perfect drug. In the early half of this decade, purchasing painkillers without a doctor was as easy as going online and checking the spam filter in your inbox. The accessibility of these drugs -- paired with a false perception of their safety -- contributed to their epidemic-like spread throughout America's twenty-something youth, a group dubbed Generation Rx. Pill Head is Joshua Lyon's harrowing and bold account of this generation, and it's also a memoir about his own struggle to recover from his addiction to painkillers. The story of so many who have shared this experience--from discovery to addiction to rehabilitation -- Pill Head follows the lives of several young people much like Joshua and dares to blow open the cultural phenomena of America's newest pill-popping generation. Marrying the journalist's eye with the addict's mind, Joshua takes readers through the shocking and often painful profiles of recreational users and suffering addicts as they fight to recover. Pill Head is not only a memoir of descent, but of endurance and of determination. Ultimately, it is a story of encouragement for anyone who is wrestling to overcome addiction, and anyone who is looking for the strength to heal.

Questions and Answers in Pain Medicine

Author : Michael Suer,Nalini Sehgal
Publisher : Springer Nature
Page : 311 pages
File Size : 53,8 Mb
Release : 2021-02-24
Category : Medical
ISBN : 9783030682040

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Questions and Answers in Pain Medicine by Michael Suer,Nalini Sehgal Pdf

This book provides a practical and comprehensive review of pain medicine in a clear and easy to apply question and answer format. Divided by topic, the book includes Q&As on Pain Basics, Psychology, Common Pain Syndromes, Medications, Pain Management in Special Populations and Interventional Pain. It is intended as a guide for residents and fellows and is written in such a manner to provide instantaneous feedback on correct answer choice and explanation for self-evaluation while preparing for written board examinations. Questions and Answers in Pain Medicine: A Guide to Board Exams fulfills the need for a resource that is similar to the Accreditation Council for Graduate Medical Education (ACGME) board examination in the US as well as international equivalents. It utilizes a fully Q&A approach which is how many students prefer to study. Written by a physician who has recently passed the ACGME written board exam and the founder of a pain management fellowship program for nearly 20 years, the authors provide valuable insight for successfully undertaking board examinations in pain medicine.