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Author : Merrill A. Biel
Publisher : Plural Publishing
Page : 213 pages
File Size : 43,8 Mb
Release : 2008-03-03
Category : Medical
ISBN : 9781597568128
Author : Dorota Bartusik-Aebisher,David Aebisher
Publisher : Nova Science Publishers
Page : 144 pages
File Size : 52,8 Mb
Release : 2021
Category : Medical
ISBN : 1536193763
"This book addresses major problem in the management of patients with cancer of the head and neck. The authors have written six chapters of particular importance for head and neck cancer diagnosis, treatment, and rehabilitation. Chapter 1 describes treatment of patients with squamous cell carcinoma of the head. Chapter 2 presents treatment of patients with squamous cell carcinoma of the neck. Biochemical studies of head and neck cancer treatments are presented in Chaper 3. In chapter 4 biochemical studies of head and neck cancer biomarkers are presented. Photodynamic therapy (PDT) exploits light interactions and photosensitizers to induce cytotoxic reactive oxygen species. Photodynamic diagnosis (PDD) uses the phenomenon of photosensitizer emitting fluorescence to distinguish some tumors from normal tissue. PDT offers a therapeutic solution that has been found to be cost-effective compared to palliative major surgery or chemotherapy. However, despite the significant improvement noted in preclinical and clinical trials, PDT is still not considered the standard treatment option for head and neck cancer. Multiple photosensitizers have been studied and tumors have been treated in a variety of head and neck sites over the last 30 years. Photodynamic therapy is a palliative treatment option for head and neck squamous cell carcinoma patients which induces local inflammation and alters tumor cell morphology"--
Author : Pandey Ravindra K,Dougherty Thomas J,Kessel David
Publisher : World Scientific
Page : 564 pages
File Size : 49,6 Mb
Release : 2016-03-24
Category : Science
ISBN : 9789814719667
The main objective of this book is to present the recent applications of photodynamic therapy (PDT) in treating cancer and other diseases. The limitations associated with current PDT agents, and the synthetic designs that have been used in various laboratories are also discussed. The utility of certain tumor-avid agent for cancer imaging (fluorescence, PET, MRI) is also summarized. The book also includes the use of delivery vehicles, including nanoparticles in improving the tumor-specificity of the desired agents. The book is basically focused on the translational approach of drug development. By providing certain specific examples, a clear concept of moving a 'product' from the bench to bed-side is also discussed.To have a clear concept of drug development the book is divided in three parts — Medicinal Chemistry, Mechanistic and Clinical studies. Each part includes the contributions from the leading scientists with extensive experience in the respective field. The handbook is assembled by renowned scientists Dr Dougherty, known as the father of PDT, Dr Kessel, well known for his contributions on mechanism of PDT and Dr Pandey for his inventions in developing improved agents for PDT and cancer-imaging.
Author : Mohamed Lotfy Taha Elsaie
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 51,6 Mb
Release : 2013
Category : Cancer
ISBN : 1624176356
"Photodynamic therapy (PDT) is currently clinically employed to treat several malignant and nonmalignant diseases. With approvals for various applications by health agencies in Europe, the US, Canada, and Japan, PDT represents the method of choice for treatment of age-related macular degeneration and is appreciated as a minimally invasive therapeutic procedure to treat skin, esophageal, head and neck, lung, and bladder cancers with high cure rates, nearly no side effects, and excellent cosmetic outcomes. Current basic research and clinical studies will help to further integrate PDT as a mainstream procedure for cancer treatment. This book presents an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases."--
Author : Mohamed Lotfy Taha Elsaie
Publisher : Unknown
Page : 287 pages
File Size : 50,5 Mb
Release : 2014-05-14
Category : Health & Fitness
ISBN : 1624176607
Photodynamic therapy (PDT) is currently clinically employed to treat several malignant and nonmalignant diseases. With approvals for various applications by health agencies in Europe, the US, Canada, and Japan, PDT represents the method of choice for treatment of age-related macular degeneration and is appreciated as a minimally invasive therapeutic procedure to treat skin, esophageal, head and neck, lung, and bladder cancers with high cure rates, nearly no side effects, and excellent cosmetic outcomes. Current basic research and clinical studies will help to further integrate PDT as a mainstream procedure for cancer treatment. This book presents an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.
Author : Charles J. Gomer
Publisher : Humana
Page : 296 pages
File Size : 46,9 Mb
Release : 2016-08-23
Category : Science
ISBN : 1493957309
Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.
Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 55,7 Mb
Release : 1999
Category : Head
ISBN : OCLC:67137187
Author : Michael H. Gold
Publisher : Springer Science & Business Media
Page : 209 pages
File Size : 46,9 Mb
Release : 2011-04-11
Category : Medical
ISBN : 9781441912985
Photodynamic therapy is a proven effective treatment of actinically damaged skin cells, nonmelanoma skin cancers, and acne and other pilosebaceous conditions. As an agent for general facial rejuvenatin it has untapped potential. The current state of PDT therapy and future applications are discussed in detail in this exciting new volume. Throughout, the focus is on evidence-based clinical uses of PDT, including pretreatment regimens, avoidance and management of complications, and posttreatment suggestions.
Author : Herwig Kostron,Tayyaba Hasan
Publisher : Royal Society of Chemistry
Page : 680 pages
File Size : 49,8 Mb
Release : 2016
Category : Science
ISBN : 9781782624516
Comprehensive Series in Photochemical and Photobiological Sciences. Photodynamic therapy (PDT) is increasingly being used amongst health practitioners in combating a variety of disease. This book reviews the current state of development of PDT, and also presents the foreseeable advancements of the field in the next decade. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find this book an invaluable source of information. Chapters are drawn from research discusses at the 10th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice in Brixen and are written and edited by leaders in the field. Mirroring the philosophy of that meeting, this book contains an informative balance of the basic sciences and clinical applications of PDT. Following an introduction to PDT, its history, and how techniques have developed, chapter serve as a practical guide for practitioners, covering topics such as sensitizer dosage and light dosage, and examples of relevant studies. The text goes further tp explore areas outside the medical field, such as the impact of PDT on society and the environment, and the economics of therapies. This book is dedicated to the memory of Professor Giulio Jori, and expert in this field, who sadly passed away on the 23rd December 2014.
Author : Yohei Tanaka
Publisher : BoD – Books on Demand
Page : 264 pages
File Size : 49,9 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9789535131557
Photomedicine is one of the most inspiring and interdisciplinary fields in medicine that involves the research and application of photobiology with respect to health and disease. Photomedicine has contributed to the clinical practice of a variety of medical fields, including dermatology, surgery, radiology, diagnostics, cardiology, and anticancer therapy. Furthermore, expansion of its scope and contribution can be expected. This book covers a wide range of aspects and issues related to photomedicine, which brings together researchers from many countries. These include the basic science of photodynamic therapy, clinical applications in various kinds of medical fields, photochemotherapy, laser therapy for musculoskeletal pain, intense pulsed light therapy for photorejuvenation, biological function of low-level laser therapy, and photobiology for skin rejuvenation. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in photomedicine.
Author : Michael R. Hamblin,Yingying Huang
Publisher : Taylor & Francis
Page : 886 pages
File Size : 47,6 Mb
Release : 2013-10-22
Category : Technology & Engineering
ISBN : 9781439884706
Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to diverse therapeutic applications of light, known collectively as phototherapies. It facilitates your understanding of human diseases caused by light, the rationale for photoprotection, and major applications of phototherapy in clinical practice. The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression. The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.
Author : Brian J.-F. Wong,Justus Ilgner
Publisher : Springer
Page : 654 pages
File Size : 40,5 Mb
Release : 2016-08-22
Category : Medical
ISBN : 9781493917587
Biomedical Optics in Otorhinolaryngology: Head and Neck Surgery gives an overview of current technology in biomedical optics relevant to the field of Otorhinolaryngology and head and neck surgery. It provides a comprehensive source of knowledge for researchers and active clinicians seeking information on the principles and practical use of novel diagnostic and therapeutic technology. While most books focus exclusively on laser surgery, which has been largely unchanged for the past 15 years, optical diagnostics and head and neck PDT (photodynamic therapy) are usually entirely overlooked. This book contains a basic introduction into the physics of light and its propagation, lasers and low-coherent light sources, and photon-tissue interaction in relation to therapeutic and diagnostic use. The principles of various imaging techniques are also discussed ( i.e. optical coherence tomography in its variations), as well as the principles and practice of lasers for surgical use on the therapeutic side.
Author : Barbara W. Henderson
Publisher : CRC Press
Page : 480 pages
File Size : 50,5 Mb
Release : 2020-07-24
Category : Photography
ISBN : 9781000104806
Covering all aspects of photodynamic therapy, 70 expert contributors from the fields of photochemistry, photobiology, photophysics, pharmacology, oncology and surgery, provide multidisciplinary discussions on photodynamic therapy - a rapidly-developing approach to the treatment of solid tumours.;Photodynamic Therapy: Basic Principles and Clinical Applications describes the molecular and cellular effects of photodynamic treatment; elucidates the complex events leading to photodynamics tissue destruction, particularly vascular and inflammatory responses; discusses the principles of light penetration through tissues and optical dosimetry; examines photosensitizer pharmacology and delivery systems; reviews in detail photosensitizer structure-activity relationships; illustrates novel devices that aid light dosimetry and fluorescence detection; and extensively delineates clinical applications, including early diagnosis and treatment.;A comprehensive and up-to-date reference, this book should be useful for oncologists, pharmacologists, surgeons, photobiologists, optical engineers, laser technicians, biologists, physicists, chemists and biochemists involved in cancer research, as well as graduate-level students in these disciplines.
Author : M.H. Gold
Publisher : Karger Medical and Scientific Publishers
Page : 146 pages
File Size : 52,9 Mb
Release : 2016-01-02
Category : Medical
ISBN : 9783318025576
Photodynamic Therapy (PDT) has become an important treatment modality in medical practice. New and exciting applications continue to emerge and the future of PDT looks brighter and brighter. Dermatologists and other health professionals around the world rely on its therapeutic effect for the treatment of actinic keratoses, non-melanoma skin cancers, acne vulgaris, and various other dermatologic conditions. In this comprehensive yet concise book, world-renowned experts showcase all of the common, everyday uses of PDT in dermatologic offices. They also examine how this beneficial therapy can be utilized to its full capacity. The considerable knowledge presented here renders this publication an indispensable resource for all dermatologists and health professionals who offer their patients this effective, noninvasive procedure.
Author : Louis B. Harrison,Roy B. Sessions,Waun Ki Hong
Publisher : Lippincott Williams & Wilkins
Page : 1004 pages
File Size : 55,9 Mb
Release : 2009
Category : Medical
ISBN : 0781771366
This comprehensive, multidisciplinary text addresses all aspects of head and neck cancer and represents a wide spectrum of specialists, including surgical, radiation, and medical oncologists, dentists, pathologists, radiologists, and nurses. The book focuses on a two-part approach to treatment that maximizes the chance for a cure while maintaining a strong emphasis on quality of life. This Third Edition's updated techniques section includes new radiation techniques such as IMRT and IGRT and new endoscopic and laser surgical techniques. Other highlights include a new chapter on reconstructive techniques; significant updates to all site-specific chapters; updates on chemoprevention and molecular targeting; and discussions of new imaging modalities such as fused PET/CT. A companion Website will offer the fully searchable text with all images.