Random Walks In Biology Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Random Walks In Biology book. This book definitely worth reading, it is an incredibly well-written.
This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know. It provides a sound basis for understanding random motions of molecules, subcellular particles, or cells, or of processes that depend on such motion or are markedly affected by it. Readers do not need to understand thermodynamics in order to acquire a knowledge of the physics involved in diffusion, sedimentation, electrophoresis, chromatography, and cell motility--subjects that become lively and immediate when the author discusses them in terms of random walks of individual particles.
Escherichia coli, commonly referred to as E. coli, has been the organism of choice for molecular genetics for decades. Its machinery and mobile behavior is one of the most fascinating topics for cell scientists. Scientists and engineers, not trained in microbiology, and who would like to learn more about living machines, can see it as a unique example. This cross-disciplinary monograph covers more than thirty years of research and is accessible to graduate students and scientists alike.
First Steps in Random Walks by J. Klafter,I. M. Sokolov Pdf
The name "random walk" for a problem of a displacement of a point in a sequence of independent random steps was coined by Karl Pearson in 1905 in a question posed to readers of "Nature". The same year, a similar problem was formulated by Albert Einstein in one of his Annus Mirabilis works. Even earlier such a problem was posed by Louis Bachelier in his thesis devoted to the theory of financial speculations in 1900. Nowadays the theory of random walks has proved useful in physics and chemistry (diffusion, reactions, mixing flows), economics, biology (from animal spread to motion of subcellular structures) and in many other disciplines. The random walk approach serves not only as a model of simple diffusion but of many complex sub- and super-diffusive transport processes as well. This book discusses the main variants of random walks and gives the most important mathematical tools for their theoretical description.
Life is a chancy proposition: from the movement of molecules to the age at which we die, chance plays a key role in the natural world. Traditionally, biologists have viewed the inevitable "noise" of life as an unfortunate complication. The authors of this book, however, treat random processes as a benefit. In this introduction to chance in biology, Mark Denny and Steven Gaines help readers to apply the probability theory needed to make sense of chance events--using examples from ocean waves to spiderwebs, in fields ranging from molecular mechanics to evolution. Through the application of probability theory, Denny and Gaines make predictions about how plants and animals work in a stochastic universe. Is it possible to pack a variety of ion channels into a cell membrane and have each operate at near-peak flow? Why are our arteries rubbery? The concept of a random walk provides the necessary insight. Is there an absolute upper limit to human life span? Could the sound of a cocktail party burst your eardrums? The statistics of extremes allows us to make the appropriate calculations. How long must you wait to see the detail in a moonlit landscape? Can you hear the noise of individual molecules? The authors provide answers to these and many other questions. After an introduction to the basic statistical methods to be used in this book, the authors emphasize the application of probability theory to biology rather than the details of the theory itself. Readers with an introductory background in calculus will be able to follow the reasoning, and sets of problems, together with their solutions, are offered to reinforce concepts. The use of real-world examples, numerous illustrations, and chapter summaries--all presented with clarity and wit--make for a highly accessible text. By relating the theory of probability to the understanding of form and function in living things, the authors seek to pique the reader's curiosity about statistics and provide a new perspective on the role of chance in biology.
Physical Biology of the Cell by Rob Phillips,Jane Kondev,Julie Theriot,Hernan Garcia Pdf
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that
Stochastic Processes in Cell Biology by Paul C. Bressloff Pdf
This book develops the theory of continuous and discrete stochastic processes within the context of cell biology. In the second edition the material has been significantly expanded, particularly within the context of nonequilibrium and self-organizing systems. Given the amount of additional material, the book has been divided into two volumes, with volume I mainly covering molecular processes and volume II focusing on cellular processes. A wide range of biological topics are covered in the new edition, including stochastic ion channels and excitable systems, molecular motors, stochastic gene networks, genetic switches and oscillators, epigenetics, normal and anomalous diffusion in complex cellular environments, stochastically-gated diffusion, active intracellular transport, signal transduction, cell sensing, bacterial chemotaxis, intracellular pattern formation, cell polarization, cell mechanics, biological polymers and membranes, nuclear structure and dynamics, biological condensates, molecular aggregation and nucleation, cellular length control, cell mitosis, cell motility, cell adhesion, cytoneme-based morphogenesis, bacterial growth, and quorum sensing. The book also provides a pedagogical introduction to the theory of stochastic and nonequilibrium processes – Fokker Planck equations, stochastic differential equations, stochastic calculus, master equations and jump Markov processes, birth-death processes, Poisson processes, first passage time problems, stochastic hybrid systems, queuing and renewal theory, narrow capture and escape, extreme statistics, search processes and stochastic resetting, exclusion processes, WKB methods, large deviation theory, path integrals, martingales and branching processes, numerical methods, linear response theory, phase separation, fluctuation-dissipation theorems, age-structured models, and statistical field theory. This text is primarily aimed at graduate students and researchers working in mathematical biology, statistical and biological physicists, and applied mathematicians interested in stochastic modeling. Applied probabilists should also find it of interest. It provides significant background material in applied mathematics and statistical physics, and introduces concepts in stochastic and nonequilibrium processes via motivating biological applications. The book is highly illustrated and contains a large number of examples and exercises that further develop the models and ideas in the body of the text. It is based on a course that the author has taught at the University of Utah for many years.
More Random Walks in Science is an anthology of fascinating and frequently amusing anecdotes, quotations, illustrations, articles, and reviews that reflect the more lighthearted aspects of the scientific world and the less serious excursions of the scientific mind. The book is guaranteed to delight anyone who has a professional or amateur interest in science.
Gandhimohan. M. Viswanathan,Marcos G. E. da Luz,Ernesto P. Raposo,H. Eugene Stanley
Author : Gandhimohan. M. Viswanathan,Marcos G. E. da Luz,Ernesto P. Raposo,H. Eugene Stanley Publisher : Cambridge University Press Page : 179 pages File Size : 41,9 Mb Release : 2011-06-02 Category : Science ISBN : 9781139497558
The Physics of Foraging by Gandhimohan. M. Viswanathan,Marcos G. E. da Luz,Ernesto P. Raposo,H. Eugene Stanley Pdf
Do the movements of animals, including humans, follow patterns that can be described quantitatively by simple laws of motion? If so, then why? These questions have attracted the attention of scientists in many disciplines, and stimulated debates ranging from ecological matters to queries such as 'how can there be free will if one follows a law of motion?' This is the first book on this rapidly evolving subject, introducing random searches and foraging in a way that can be understood by readers without a previous background on the subject. It reviews theory as well as experiment, addresses open problems and perspectives, and discusses applications ranging from the colonization of Madagascar by Austronesians to the diffusion of genetically modified crops. The book will interest physicists working in the field of anomalous diffusion and movement ecology as well as ecologists already familiar with the concepts and methods of statistical physics.
Intersections of Random Walks by Gregory F. Lawler Pdf
A central study in Probability Theory is the behavior of fluctuation phenomena of partial sums of different types of random variable. One of the most useful concepts for this purpose is that of the random walk which has applications in many areas, particularly in statistical physics and statistical chemistry. Originally published in 1991, Intersections of Random Walks focuses on and explores a number of problems dealing primarily with the nonintersection of random walks and the self-avoiding walk. Many of these problems arise in studying statistical physics and other critical phenomena. Topics include: discrete harmonic measure, including an introduction to diffusion limited aggregation (DLA); the probability that independent random walks do not intersect; and properties of walks without self-intersections. The present softcover reprint includes corrections and addenda from the 1996 printing, and makes this classic monograph available to a wider audience. With a self-contained introduction to the properties of simple random walks, and an emphasis on rigorous results, the book will be useful to researchers in probability and statistical physics and to graduate students interested in basic properties of random walks.
Kermit the Frog famously said that it isn’t easy being green, and in Living at Micro Scale David Dusenbery shows that it isn’t easy being small—existing at the size of, say, a rotifer, a tiny multicellular animal just at the boundary between the visible and the microscopic. “Imagine,” he writes, “stepping off a curb and waiting a week for your foot to hit the ground.” At that scale, we would be small enough to swim inside the letter O in the word “rotifer.” What are the physical consequences of life at this scale? How do such organisms move, identify prey and predators and (if they’re so inclined) mates, signal to one another, and orient themselves? In clear and engaging prose, Dusenbery uses straightforward physics to demonstrate the constraints on the size, shape, and behavior of tiny organisms. While recounting the historical development of the basic concepts, he unearths a corner of microbiology rich in history, and full of lessons about how science does or does not progress. Marshalling findings from different fields to show why tiny organisms have some of the properties they are found to have, Dusenbery shows a science that doesn’t always move triumphantly forward, and is dependent to a great extent on accident and contingency.
Random Walks and Electric Networks by Peter G. Doyle,J. Laurie Snell Pdf
Probability theory, like much of mathematics, is indebted to physics as a source of problems and intuition for solving these problems. Unfortunately, the level of abstraction of current mathematics often makes it difficult for anyone but an expert to appreciate this fact. Random Walks and electric networks looks at the interplay of physics and mathematics in terms of an example—the relation between elementary electric network theory and random walks —where the mathematics involved is at the college level.
A Non-Random Walk Down Wall Street by Andrew W. Lo,A. Craig MacKinlay Pdf
For over half a century, financial experts have regarded the movements of markets as a random walk--unpredictable meanderings akin to a drunkard's unsteady gait--and this hypothesis has become a cornerstone of modern financial economics and many investment strategies. Here Andrew W. Lo and A. Craig MacKinlay put the Random Walk Hypothesis to the test. In this volume, which elegantly integrates their most important articles, Lo and MacKinlay find that markets are not completely random after all, and that predictable components do exist in recent stock and bond returns. Their book provides a state-of-the-art account of the techniques for detecting predictabilities and evaluating their statistical and economic significance, and offers a tantalizing glimpse into the financial technologies of the future. The articles track the exciting course of Lo and MacKinlay's research on the predictability of stock prices from their early work on rejecting random walks in short-horizon returns to their analysis of long-term memory in stock market prices. A particular highlight is their now-famous inquiry into the pitfalls of "data-snooping biases" that have arisen from the widespread use of the same historical databases for discovering anomalies and developing seemingly profitable investment strategies. This book invites scholars to reconsider the Random Walk Hypothesis, and, by carefully documenting the presence of predictable components in the stock market, also directs investment professionals toward superior long-term investment returns through disciplined active investment management.
Random Walks and Diffusion by Open University Course Team,Open University MS324/Block 2 Pdf
This block explores the diffusion equation which is most commonly encountered in discussions of the flow of heat and of molecules moving in liquids, but diffusion equations arise from many different areas of applied mathematics. As well as considering the solutions of diffusion equations in detail, we also discuss the microscopic mechanism underlying the diffusion equation, namely that particles of matter or heat move erratically. This involves a discussion of elementary probability and statistics, which are used to develop a description of random walk processes and of the central limit theorem. These concepts are used to show that if particles follow random walk trajectories, their density obeys the diffusion equation.
Classical and Spatial Stochastic Processes by Rinaldo B. Schinazi Pdf
The revised and expanded edition of this textbook presents the concepts and applications of random processes with the same illuminating simplicity as its first edition, but with the notable addition of substantial modern material on biological modeling. While still treating many important problems in fields such as engineering and mathematical physics, the book also focuses on the highly relevant topics of cancerous mutations, influenza evolution, drug resistance, and immune response. The models used elegantly apply various classical stochastic models presented earlier in the text, and exercises are included throughout to reinforce essential concepts. The second edition of Classical and Spatial Stochastic Processes is suitable as a textbook for courses in stochastic processes at the advanced-undergraduate and graduate levels, or as a self-study resource for researchers and practitioners in mathematics, engineering, physics, and mathematical biology. Reviews of the first edition: An appetizing textbook for a first course in stochastic processes. It guides the reader in a very clever manner from classical ideas to some of the most interesting modern results. ... All essential facts are presented with clear proofs, illustrated by beautiful examples. ... The book is well organized, has informative chapter summaries, and presents interesting exercises. The clear proofs are concentrated at the ends of the chapters making it easy to find the results. The style is a good balance of mathematical rigorosity and user-friendly explanation. —Biometric Journal This small book is well-written and well-organized. ... Only simple results are treated ... but at the same time many ideas needed for more complicated cases are hidden and in fact very close. The second part is a really elementary introduction to the area of spatial processes. ... All sections are easily readable and it is rather tentative for the reviewer to learn them more deeply by organizing a course based on this book. The reader can be really surprised seeing how simple the lectures on these complicated topics can be. At the same time such important questions as phase transitions and their properties for some models and the estimates for certain critical values are discussed rigorously. ... This is indeed a first course on stochastic processes and also a masterful introduction to some modern chapters of the theory. —Zentralblatt Math
Cell Biology by the Numbers by Ron Milo,Rob Phillips Pdf
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
