Secondary Analysis Of Electronic Health Records

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Secondary Analysis of Electronic Health Records

Author : MIT Critical Data
Publisher : Springer
Page : 427 pages
File Size : 50,5 Mb
Release : 2016-09-09
Category : Medical
ISBN : 9783319437422

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Secondary Analysis of Electronic Health Records by MIT Critical Data Pdf

This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Secondary Analysis of Electronic Health Records

Author : MIT Critical Data
Publisher : Springer
Page : 609 pages
File Size : 55,6 Mb
Release : 2016-10-02
Category : Medical
ISBN : 3319437402

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Secondary Analysis of Electronic Health Records by MIT Critical Data Pdf

This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Clinical Text Mining

Author : Hercules Dalianis
Publisher : Springer
Page : 192 pages
File Size : 49,5 Mb
Release : 2018-05-14
Category : Computers
ISBN : 9783319785035

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Clinical Text Mining by Hercules Dalianis Pdf

This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records. It is divided into twelve chapters. Chapters 1-4 discuss the history and background of the original paper-based patient records, their purpose, and how they are written and structured. These initial chapters do not require any technical or medical background knowledge. The remaining eight chapters are more technical in nature and describe various medical classifications and terminologies such as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, and ATC. Chapters 5-10 cover basic tools for natural language processing and information retrieval, and how to apply them to clinical text. The difference between rule-based and machine learning-based methods, as well as between supervised and unsupervised machine learning methods, are also explained. Next, ethical concerns regarding the use of sensitive patient records for research purposes are discussed, including methods for de-identifying electronic patient records and safely storing patient records. The book’s closing chapters present a number of applications in clinical text mining and summarise the lessons learned from the previous chapters. The book provides a comprehensive overview of technical issues arising in clinical text mining, and offers a valuable guide for advanced students in health informatics, computational linguistics, and information retrieval, and for researchers entering these fields.

Registries for Evaluating Patient Outcomes

Author : Agency for Healthcare Research and Quality/AHRQ
Publisher : Government Printing Office
Page : 396 pages
File Size : 48,6 Mb
Release : 2014-04-01
Category : Medical
ISBN : 9781587634338

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Registries for Evaluating Patient Outcomes by Agency for Healthcare Research and Quality/AHRQ Pdf

This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Leveraging Data Science for Global Health

Author : Leo Anthony Celi,Maimuna S. Majumder,Patricia Ordóñez,Juan Sebastian Osorio,Kenneth E. Paik,Melek Somai
Publisher : Springer Nature
Page : 471 pages
File Size : 44,7 Mb
Release : 2020-07-31
Category : Medical
ISBN : 9783030479947

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Leveraging Data Science for Global Health by Leo Anthony Celi,Maimuna S. Majumder,Patricia Ordóñez,Juan Sebastian Osorio,Kenneth E. Paik,Melek Somai Pdf

This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient.

Occupational Outlook Handbook

Author : United States. Bureau of Labor Statistics
Publisher : Unknown
Page : 740 pages
File Size : 43,7 Mb
Release : 1957
Category : Employment forecasting
ISBN : IND:30000089076727

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Occupational Outlook Handbook by United States. Bureau of Labor Statistics Pdf

Drug Utilization Research

Author : Monique Elseviers,Björn Wettermark,Anna Birna Almarsdóttir,Morten Andersen,Ria Benko,Marion Bennie,Irene Eriksson,Brian Godman,Janet Krska,Elisabetta Poluzzi,Kstja Taxis,Vera Vlahovic-Palcevski,Robert Vander Stichele
Publisher : John Wiley & Sons
Page : 548 pages
File Size : 41,7 Mb
Release : 2016-05-31
Category : Medical
ISBN : 9781118949788

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Drug Utilization Research by Monique Elseviers,Björn Wettermark,Anna Birna Almarsdóttir,Morten Andersen,Ria Benko,Marion Bennie,Irene Eriksson,Brian Godman,Janet Krska,Elisabetta Poluzzi,Kstja Taxis,Vera Vlahovic-Palcevski,Robert Vander Stichele Pdf

Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understanding and evaluation of the processes of prescribing, dispensing and consumption of medicines and for the testing of interventions to enhance the quality of these processes. The discipline is closely related and linked mainly to the broader field of pharmacoepidemiology, but also to health outcomes research, pharmacovigilance and health economics. Drug Utilization Research is a unique, practical guide to the assessment and evaluation of prescribing practices and to interventions to improve the use of medicines in populations. Edited by an international expert team from the International Society for Pharmacoepidemiology (ISPE), DUR is the only title to cover both the methodology and applications of drug utilization research and covers areas such as health policy, specific populations, therapeutics and adherence.

The Computer-Based Patient Record

Author : Committee on Improving the Patient Record,Institute of Medicine
Publisher : National Academies Press
Page : 215 pages
File Size : 53,7 Mb
Release : 1997-10-28
Category : Medical
ISBN : 9780309578851

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The Computer-Based Patient Record by Committee on Improving the Patient Record,Institute of Medicine Pdf

Most industries have plunged into data automation, but health care organizations have lagged in moving patients' medical records from paper to computers. In its first edition, this book presented a blueprint for introducing the computer-based patient record (CPR). The revised edition adds new information to the original book. One section describes recent developments, including the creation of a computer-based patient record institute. An international chapter highlights what is new in this still-emerging technology. An expert committee explores the potential of machine-readable CPRs to improve diagnostic and care decisions, provide a database for policymaking, and much more, addressing these key questions: Who uses patient records? What technology is available and what further research is necessary to meet users' needs? What should government, medical organizations, and others do to make the transition to CPRs? The volume also explores such issues as privacy and confidentiality, costs, the need for training, legal barriers to CPRs, and other key topics.

For the Record

Author : National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Commission on Physical Sciences, Mathematics, and Applications,Committee on Maintaining Privacy and Security in Health Care Applications of the National Information Infrastructure
Publisher : National Academies Press
Page : 287 pages
File Size : 55,7 Mb
Release : 1997-07-09
Category : Medical
ISBN : 9780309056977

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For the Record by National Research Council,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Commission on Physical Sciences, Mathematics, and Applications,Committee on Maintaining Privacy and Security in Health Care Applications of the National Information Infrastructure Pdf

When you visit the doctor, information about you may be recorded in an office computer. Your tests may be sent to a laboratory or consulting physician. Relevant information may be transmitted to your health insurer or pharmacy. Your data may be collected by the state government or by an organization that accredits health care or studies medical costs. By making information more readily available to those who need it, greater use of computerized health information can help improve the quality of health care and reduce its costs. Yet health care organizations must find ways to ensure that electronic health information is not improperly divulged. Patient privacy has been an issue since the oath of Hippocrates first called on physicians to "keep silence" on patient matters, and with highly sensitive dataâ€"genetic information, HIV test results, psychiatric recordsâ€"entering patient records, concerns over privacy and security are growing. For the Record responds to the health care industry's need for greater guidance in protecting health information that increasingly flows through the national information infrastructureâ€"from patient to provider, payer, analyst, employer, government agency, medical product manufacturer, and beyond. This book makes practical detailed recommendations for technical and organizational solutions and national-level initiatives. For the Record describes two major types of privacy and security concerns that stem from the availability of health information in electronic form: the increased potential for inappropriate release of information held by individual organizations (whether by those with access to computerized records or those who break into them) and systemic concerns derived from open and widespread sharing of data among various parties. The committee reports on the technological and organizational aspects of security management, including basic principles of security; the effectiveness of technologies for user authentication, access control, and encryption; obstacles and incentives in the adoption of new technologies; and mechanisms for training, monitoring, and enforcement. For the Record reviews the growing interest in electronic medical records; the increasing value of health information to providers, payers, researchers, and administrators; and the current legal and regulatory environment for protecting health data. This information is of immediate interest to policymakers, health policy researchers, patient advocates, professionals in health data management, and other stakeholders.

Deep Learning Techniques for Biomedical and Health Informatics

Author : Basant Agarwal,Valentina Emilia Balas,Lakhmi C. Jain,Ramesh Chandra Poonia,Manisha Sharma
Publisher : Academic Press
Page : 367 pages
File Size : 43,6 Mb
Release : 2020-01-14
Category : Science
ISBN : 9780128190623

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Deep Learning Techniques for Biomedical and Health Informatics by Basant Agarwal,Valentina Emilia Balas,Lakhmi C. Jain,Ramesh Chandra Poonia,Manisha Sharma Pdf

Deep Learning Techniques for Biomedical and Health Informatics provides readers with the state-of-the-art in deep learning-based methods for biomedical and health informatics. The book covers not only the best-performing methods, it also presents implementation methods. The book includes all the prerequisite methodologies in each chapter so that new researchers and practitioners will find it very useful. Chapters go from basic methodology to advanced methods, including detailed descriptions of proposed approaches and comprehensive critical discussions on experimental results and how they are applied to Biomedical Engineering, Electronic Health Records, and medical image processing. Examines a wide range of Deep Learning applications for Biomedical Engineering and Health Informatics, including Deep Learning for drug discovery, clinical decision support systems, disease diagnosis, prediction and monitoring Discusses Deep Learning applied to Electronic Health Records (EHR), including health data structures and management, deep patient similarity learning, natural language processing, and how to improve clinical decision-making Provides detailed coverage of Deep Learning for medical image processing, including optimizing medical big data, brain image analysis, brain tumor segmentation in MRI imaging, and the future of biomedical image analysis

Pharmacoepidemiology

Author : Brian L. Strom,Stephen E. Kimmel,Sean Hennessy
Publisher : John Wiley & Sons
Page : 1220 pages
File Size : 48,9 Mb
Release : 2019-12-16
Category : Medical
ISBN : 9781119413417

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Pharmacoepidemiology by Brian L. Strom,Stephen E. Kimmel,Sean Hennessy Pdf

This classic, field-defining textbook, now in its sixth edition, provides the most comprehensive guidance available for anyone needing up-to-date information in pharmacoepidemiology. This edition has been fully revised and updated throughout and continues to provide a rounded view on all perspectives from academia, industry and regulatory bodies, addressing data sources, applications and methodologies with great clarity.

Principles and Practice of Clinical Research

Author : John I. Gallin,Frederick P Ognibene
Publisher : Elsevier
Page : 448 pages
File Size : 47,5 Mb
Release : 2011-04-28
Category : Medical
ISBN : 0080489567

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Principles and Practice of Clinical Research by John I. Gallin,Frederick P Ognibene Pdf

The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government

Global Health Informatics

Author : Leo Anthony G. Celi,Hamish S. F. Fraser,Vipan Nikore,Juan Sebastian Osorio,Kenneth Paik
Publisher : MIT Press
Page : 465 pages
File Size : 53,6 Mb
Release : 2017-04-21
Category : Medical
ISBN : 9780262533201

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Global Health Informatics by Leo Anthony G. Celi,Hamish S. F. Fraser,Vipan Nikore,Juan Sebastian Osorio,Kenneth Paik Pdf

Key concepts, frameworks, examples, and lessons learned in designing and implementing health information and communication technology systems in the developing world. The widespread usage of mobile phones that bring computational power and data to our fingertips has enabled new models for tracking and battling disease. The developing world in particular has become a proving ground for innovation in eHealth (using communication and technology tools in healthcare) and mHealth (using the affordances of mobile technology in eHealth systems). In this book, experts from a variety of disciplines—among them computer science, medicine, public health, policy, and business—discuss key concepts, frameworks, examples, and lessons learned in designing and implementing digital health systems in the developing world. The contributors consider such topics as global health disparities and quality of care; aligning eHealth strategies with government policy; the role of monitoring and evaluation in improving care; databases, patient registries, and electronic health records; the lifecycle of a digital health system project; software project management; privacy and security; and evaluating health technology systems.

Anonymizing Health Data

Author : Khaled El Emam,Luk Arbuckle
Publisher : "O'Reilly Media, Inc."
Page : 228 pages
File Size : 55,5 Mb
Release : 2013-12-11
Category : Computers
ISBN : 9781449363031

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Anonymizing Health Data by Khaled El Emam,Luk Arbuckle Pdf

Updated as of August 2014, this practical book will demonstrate proven methods for anonymizing health data to help your organization share meaningful datasets, without exposing patient identity. Leading experts Khaled El Emam and Luk Arbuckle walk you through a risk-based methodology, using case studies from their efforts to de-identify hundreds of datasets. Clinical data is valuable for research and other types of analytics, but making it anonymous without compromising data quality is tricky. This book demonstrates techniques for handling different data types, based on the authors’ experiences with a maternal-child registry, inpatient discharge abstracts, health insurance claims, electronic medical record databases, and the World Trade Center disaster registry, among others. Understand different methods for working with cross-sectional and longitudinal datasets Assess the risk of adversaries who attempt to re-identify patients in anonymized datasets Reduce the size and complexity of massive datasets without losing key information or jeopardizing privacy Use methods to anonymize unstructured free-form text data Minimize the risks inherent in geospatial data, without omitting critical location-based health information Look at ways to anonymize coding information in health data Learn the challenge of anonymously linking related datasets