Single Molecule Cellular Biophysics

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Single-Molecule Cellular Biophysics

Author : Mark C. Leake
Publisher : Cambridge University Press
Page : 292 pages
File Size : 46,8 Mb
Release : 2013-01-31
Category : Science
ISBN : 9781107005839

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Single-Molecule Cellular Biophysics by Mark C. Leake Pdf

Indispensable textbook for undergraduate students in the physical and life sciences, unravelling the inner workings of the cell.

Single-Molecule Cellular Biophysics

Author : Mark C. Leake
Publisher : Cambridge University Press
Page : 128 pages
File Size : 47,8 Mb
Release : 2013-01-31
Category : Science
ISBN : 9781139619349

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Single-Molecule Cellular Biophysics by Mark C. Leake Pdf

Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the physical and life sciences. Mathematical derivations are kept to a minimum whilst unnecessary biological terminology is avoided and text boxes provide readers from either background with additional information. 100 end-of-chapter exercises are divided into those aimed at physical sciences students, those aimed at life science students and those that can be tackled by students from both disciplines. The use of case studies and real research examples make this textbook indispensable for undergraduate students entering this exciting field.

Single Molecule Cellular Biophysics

Author : Royal Society (Great Britain)
Publisher : Unknown
Page : 128 pages
File Size : 41,8 Mb
Release : 2012
Category : Cytology
ISBN : 0854039902

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Single Molecule Cellular Biophysics by Royal Society (Great Britain) Pdf

An Introduction to Single Molecule Biophysics

Author : Yuri L. Lyubchenko
Publisher : CRC Press
Page : 240 pages
File Size : 42,7 Mb
Release : 2017-11-22
Category : Science
ISBN : 9781351333122

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An Introduction to Single Molecule Biophysics by Yuri L. Lyubchenko Pdf

This book gives an accessible, detailed overview on techniques of single molecule biophysics (SMB), showing how they are applied to numerous biological problems associated with understanding the molecular mechanisms of DNA replication, transcription, and translation, as well as functioning of molecular machines. It covers major single molecule imaging and probing techniques, highlighting key strengths and limitations of each method using recent examples. The chapters begin with a discussion of single molecule fluorescence techniques followed by an overview of the atomic force microscope and its use for direct time-lapse visualization of dynamics of molecular complexes at the nanoscale, as well as applications in measurements of interactions between molecules and mechanical properties of isolated molecules and their complexes. The next chapters address magnetic tweezers and optical tweezers, including instrumentation, fundamentals of operation, and applications. A final chapter turns to nanopore transport and nanopore-based DNA sequencing technology that will play a major role in next-generation genomics and healthcare applications.

Single-Molecule Biophysics

Author : Tamiki Komatsuzaki,Masaru Kawakami,Satoshi Takahashi,Haw Yang,Robert J. Silbey
Publisher : John Wiley & Sons
Page : 512 pages
File Size : 54,7 Mb
Release : 2011-11-16
Category : Science
ISBN : 9781118131381

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Single-Molecule Biophysics by Tamiki Komatsuzaki,Masaru Kawakami,Satoshi Takahashi,Haw Yang,Robert J. Silbey Pdf

Discover the experimental and theoretical developments inoptical single-molecule spectroscopy that are changing the ways wethink about molecules and atoms The Advances in Chemical Physics series provides thechemical physics field with a forum for critical, authoritativeevaluations of advances in every area of the discipline. Thislatest volume explores the advent of optical single-moleculespectroscopy, and how atomic force microscopy has empowered novelexperiments on individual biomolecules, opening up new frontiers inmolecular and cell biology and leading to new theoreticalapproaches and insights. Organized into two parts—oneexperimental, the other theoretical—this volume exploresadvances across the field of single-molecule biophysics, presentingnew perspectives on the theoretical properties of atoms andmolecules. Single-molecule experiments have provided freshperspectives on questions such as how proteins fold to specificconformations from highly heterogeneous structures, how signaltransductions take place on the molecular level, and how proteinsbehave in membranes and living cells.This volume is designed tofurther contribute to the rapid development of single-moleculebiophysics research. Filled with cutting-edge research reported in a cohesive mannernot found elsewhere in the literature, each volume of theAdvances in Chemical Physics series serves as the perfectsupplement to any advanced graduate class devoted to the study ofchemical physics.

Molecular and Cellular Biophysics

Author : Meyer B. Jackson
Publisher : Cambridge University Press
Page : 128 pages
File Size : 55,7 Mb
Release : 2006-01-12
Category : Science
ISBN : 1139447246

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Molecular and Cellular Biophysics by Meyer B. Jackson Pdf

Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics

Author : Susanta K Sarkar
Publisher : Morgan & Claypool Publishers
Page : 74 pages
File Size : 52,9 Mb
Release : 2016-04-01
Category : Science
ISBN : 9781681741161

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Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics by Susanta K Sarkar Pdf

This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.

Studyguide for Single-Molecule Cellular Biophysics by Mark C. Leake, ISBN 9781107005839

Author : Cram101 Incorporated,Cram101 Textbook Reviews
Publisher : Cram101
Page : 152 pages
File Size : 55,6 Mb
Release : 2014-01
Category : Electronic
ISBN : 1478481102

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Studyguide for Single-Molecule Cellular Biophysics by Mark C. Leake, ISBN 9781107005839 by Cram101 Incorporated,Cram101 Textbook Reviews Pdf

Never HIGHLIGHT a Book Again! Virtually all of the testable terms, concepts, persons, places, and events from the textbook are included. Cram101 Just the FACTS101 studyguides give all of the outlines, highlights, notes, and quizzes for your textbook with optional online comprehensive practice tests. Only Cram101 is Textbook Specific. Accompanys: 9781107005839 .

Single Molecules and Nanotechnology

Author : Rudolf Rigler,H. Vogel
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 55,5 Mb
Release : 2007-12-07
Category : Technology & Engineering
ISBN : 9783540739241

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Single Molecules and Nanotechnology by Rudolf Rigler,H. Vogel Pdf

This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including quantum photonics of organic dyes and inorganic nanoparticles and monitoring of single molecule (enzymatic) reactions.

Handbook of Single-Molecule Biophysics

Author : Peter Hinterdorfer,Antoine van Oijen
Publisher : Springer
Page : 626 pages
File Size : 50,7 Mb
Release : 2016-08-23
Category : Science
ISBN : 149393919X

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Handbook of Single-Molecule Biophysics by Peter Hinterdorfer,Antoine van Oijen Pdf

This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Handbook of Single-Molecule Biophysics

Author : Peter Hinterdorfer,Antoine van Oijen
Publisher : Springer
Page : 626 pages
File Size : 41,7 Mb
Release : 2009-07-24
Category : Science
ISBN : 0387764968

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Handbook of Single-Molecule Biophysics by Peter Hinterdorfer,Antoine van Oijen Pdf

This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Single Molecule Analysis

Author : Erwin J. G. Peterman,Gijs J. L. Wuite
Publisher : Humana Press
Page : 317 pages
File Size : 54,8 Mb
Release : 2016-08-23
Category : Science
ISBN : 1493958291

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Single Molecule Analysis by Erwin J. G. Peterman,Gijs J. L. Wuite Pdf

Life scientists believe that life is driven, directed, and shaped by biomolecules working on their own or in concert. It is only in the last few decades that technological breakthroughs in sensitive fluorescence microscopy and single-molecule manipulation techniques have made it possible to observe and manipulate single biomolecules and measure their individual properties. The methodologies presented in Single Molecule Techniques: Methods and Protocols are being applied more and more to the study of biologically relevant molecules, such as DNA, DNA-binding proteins, and motor proteins, and are becoming commonplace in molecular biophysics, biochemistry, and molecular and cell biology. The aim of Single Molecule Techniques: Methods and Protocols is to provide a broad overview of single-molecule approaches applied to biomolecules on the basis of clear and concise protocols, including a solid introduction to the most widely used single-molecule techniques, such as optical tweezers, single-molecule fluorescence tools, atomic force microscopy, magnetic tweezers, and tethered particle motion. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Single Molecule Techniques: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and provides a broad and thorough overview of the exciting and still-emerging field of single-molecule biology.

Molecular and Cellular Biophysics

Author : Jack A. Tuszynski
Publisher : CRC Press
Page : 540 pages
File Size : 46,9 Mb
Release : 2018-10-24
Category : Science
ISBN : 9781420011722

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Molecular and Cellular Biophysics by Jack A. Tuszynski Pdf

From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation. Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.

Biology at the Single Molecule Level

Author : S.H. Leuba,J. Zlatanova
Publisher : Elsevier
Page : 262 pages
File Size : 53,6 Mb
Release : 2001-12-17
Category : Science
ISBN : 008056061X

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Biology at the Single Molecule Level by S.H. Leuba,J. Zlatanova Pdf

This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.

Single-molecule Studies of Proteins

Author : Andres F. Oberhauser
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 43,9 Mb
Release : 2012-11-09
Category : Science
ISBN : 9781461449218

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Single-molecule Studies of Proteins by Andres F. Oberhauser Pdf

In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.