Ten Drugs

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Ten Drugs

Author : Thomas Hager
Publisher : Abrams
Page : 342 pages
File Size : 47,9 Mb
Release : 2019-03-05
Category : Medical
ISBN : 9781683355311

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Ten Drugs by Thomas Hager Pdf

“The stories are skillfully told and entirely entertaining . . . An expert, mostly feel-good book about modern medicine” from the award-winning author (Kirkus Reviews, starred review). Behind every landmark drug is a story. It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine. Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book. “[An] absorbing new book.” —The New York Times Book Review “[A] well-written and engaging chronicle.” —The Wall Street Journal “Lucidly informative and compulsively readable.” —Publishers Weekly “Entertaining [and] insightful.” —Booklist “Well-written, well-researched and fascinating to read Ten Drugs provides an insightful look at how drugs have shaped modern medical practices. Towards the end of the book Hager writes that he ‘came away surprised by some of the things he had learned.’ I had the very same reaction.” —Penny Le Couteur, coauthor of Napoleon’s Buttons: How 17 Molecules Changed History

Ten Drugs

Author : Thomas Hager
Publisher : Abrams Press
Page : 0 pages
File Size : 42,7 Mb
Release : 2020-04-07
Category : Drugs
ISBN : 1419735225

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Ten Drugs by Thomas Hager Pdf

Profiles ten drugs, discussing their discovery and significance to the history of medicine.

Ten Drugs

Author : Thomas Hager
Publisher : Harry N. Abrams
Page : 0 pages
File Size : 46,7 Mb
Release : 2019-03-05
Category : Science
ISBN : 1419734407

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Ten Drugs by Thomas Hager Pdf

Beginning with opium, the "joy plant," which has been used for 10,000 years, Hager's subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain; the infamous knockout drops; the first antibiotic, which saved countless lives; the first antipsychotic, which helped empty public mental hospitals; Viagra, statins; and the new frontier of monoclonal antibodies.

The Demon Under the Microscope

Author : Thomas Hager
Publisher : Crown
Page : 354 pages
File Size : 50,9 Mb
Release : 2007-08-28
Category : Science
ISBN : 9781400082148

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The Demon Under the Microscope by Thomas Hager Pdf

In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of sulfa, the first antibiotic and the drug that shaped modern medicine. The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. Sulfa saved millions of lives—among them those of Winston Churchill and Franklin Delano Roosevelt Jr.—but its real effects are even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold; transformed the way doctors treated patients; and ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness. A strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel.

Synthesis of Best-Seller Drugs

Author : Ruben Vardanyan,Victor Hruby
Publisher : Academic Press
Page : 868 pages
File Size : 44,8 Mb
Release : 2016-01-07
Category : Science
ISBN : 9780124115248

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Synthesis of Best-Seller Drugs by Ruben Vardanyan,Victor Hruby Pdf

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Drug Safety

Author : United States. General Accounting Office
Publisher : Unknown
Page : 12 pages
File Size : 42,5 Mb
Release : 2001
Category : Drugs
ISBN : UCBK:C079752088

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Drug Safety by United States. General Accounting Office Pdf

Drugged

Author : Richard J. Miller
Publisher : Oxford University Press, USA
Page : 375 pages
File Size : 44,7 Mb
Release : 2014
Category : Medical
ISBN : 9780199957972

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Drugged by Richard J. Miller Pdf

Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.

Random Family

Author : Adrian Nicole LeBlanc
Publisher : Simon and Schuster
Page : 432 pages
File Size : 46,9 Mb
Release : 2012-10-23
Category : Biography & Autobiography
ISBN : 9781439124895

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Random Family by Adrian Nicole LeBlanc Pdf

This New York Times bestseller intimately depicts urban life in a gripping book that slips behind cold statistics and sensationalism to reveal the true sagas lurking behind the headlines of gangsta glamour. In her extraordinary bestseller, Adrian Nicole LeBlanc immerses readers in the intricacies of the ghetto, revealing the true sagas lurking behind the headlines of gangsta glamour, gold-drenched drug dealers, and street-corner society. Focusing on two romances—Jessica’s dizzying infatuation with a hugely successful young heroin dealer, Boy George, and Coco’s first love with Jessica's little brother, Cesar—Random Family is the story of young people trying to outrun their destinies. Jessica and Boy George ride the wild adventure between riches and ruin, while Coco and Cesar stick closer to the street, all four caught in a precarious dance between survival and death. Friends get murdered; the DEA and FBI investigate Boy George; Cesar becomes a fugitive; Jessica and Coco endure homelessness, betrayal, the heartbreaking separation of prison, and, throughout it all, the insidious damage of poverty. Charting the tumultuous cycle of the generations—as girls become mothers, boys become criminals, and hope struggles against deprivation—LeBlanc slips behind the cold statistics and sensationalism and comes back with a riveting, haunting, and true story.

Cholesterol Down

Author : Janet Bond Brill, PhD, RD, LDN
Publisher : Harmony
Page : 338 pages
File Size : 53,8 Mb
Release : 2009-01-21
Category : Health & Fitness
ISBN : 9780307494467

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Cholesterol Down by Janet Bond Brill, PhD, RD, LDN Pdf

Take control of your cholesterol with this 10-point plan from nutrition and fitness expert Dr. Janet Brill—without using drugs. If you are one of the nearly 100 million Americans struggling with high cholesterol, then Dr. Janet Brill offers you a revolutionary new plan for taking control of your health—without the risks of statin drugs. With Dr. Brill’s breakthrough Cholesterol Down Plan, you simply add nine “miracle foods” to your regular diet and thirty minutes of walking to your daily routine. That’s all. This straightforward and easy-to-follow program can lower your LDL (“bad”) cholesterol by as much as 47 percent in just four weeks. Cholesterol Down explains Dr. Brill’s ten-point plan as well as the science behind it. You’ll learn how each miracle food affects LDL cholesterol and how the foods work together for maximum effect, as well as: • How eating whole grains helps reduce LDL cholesterol in your bloodstream • Why antioxidants keep plaque from building up in your arteries • How certain steps change the structure of LDL cholesterol particles (and why it’s best for them to be large and fluffy) • Why walking just thirty minutes a day lowers “bad” cholesterol and cuts dangerous belly fat With everything you need to stay focused on the plan, including a daily checklist, a six-month chart for racking LDL cholesterol changes, tools for assessing your risk level for cardiovascular disease, sample weekly menus, and even heart-healthy recipes, Cholesterol Down is the safe and effective alternative or complement to statin drugs.

Synthesis of Essential Drugs

Author : Ruben Vardanyan,Victor Hruby
Publisher : Elsevier
Page : 634 pages
File Size : 51,9 Mb
Release : 2006-03-10
Category : Medical
ISBN : 008046212X

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Synthesis of Essential Drugs by Ruben Vardanyan,Victor Hruby Pdf

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

Blood Pressure Down

Author : Janet Bond Brill, PhD, RD, LDN
Publisher : Harmony
Page : 354 pages
File Size : 41,6 Mb
Release : 2013-05-07
Category : Health & Fitness
ISBN : 9780307986368

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Blood Pressure Down by Janet Bond Brill, PhD, RD, LDN Pdf

For the nearly 78 million Americans with hypertension, a safe, effective lifestyle plan—incorporating the DASH diet principles and much more—for lowering blood pressure naturally If you have high blood pressure, you're not alone: nearly a third of adult Americans have been diagnosed with hypertension, and another quarter are well on their way. Yet a whopping 56 percent of diagnosed patients do not have it under control. The good news? Hypertension is easily treatable (and preventable), and you can take action today to bring your blood pressure down in just four weeks—without the potential dangers and side effects of prescription medications. In Blood Pressure Down, Janet Bond Brill distills what she's learned over decades of helping her patients lower their blood pressure into a ten-step lifestyle plan that's manageable for anyone. You'll: • harness the power of blood pressure power foods like bananas, spinach, and yogurt • start a simple regimen of exercise and stress reduction • stay on track with checklists, meal plans, and more than fifty simple recipes Easy, effective, safe—and delicious—Blood Pressure Down is the encouraging resource that empowers you, or your loved ones, to lower your blood pressure and live a longer, heart-healthy life.

Drug-Induced Liver Injury

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 50,7 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Drug-Induced Headache

Author : Hans-Christoph Diener,Marcia Wilkinson
Publisher : Springer Science & Business Media
Page : 174 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642733277

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Drug-Induced Headache by Hans-Christoph Diener,Marcia Wilkinson Pdf

M. WILKINSON Patients with frequent or daily headaches pose a very difficult problem for the physician who has to treat them, particularly as many patients think that there should be a medicine or medicines which give them instant relief. In the search for the compound which would meet this very natural desire, many drugs have been manufactured and the temptation for the physician is either to increase the dose of a drug which seems to be, at any rate, partially effective, or to add one or more drugs to those which the patient is already taking. Although there have been some references to the dangers of overdosage of drugs for migraine in the past, it was not until relatively recently that it was recognized that drugs given for the relief of headache, if taken injudiciously, may themselves cause headache. The first drugs to be implicated in this way were ergotamine and phenazone. In the case of ergotamine tartrate, the dangers of ergotism were well known as this was a disorder which had been known and written about for many years. In the treatment of headache, fully blown ergotism is rare and in recent years has usually been due to self-medication in doses much greater than those prescribed although there are a few recorded cases where toxic amounts have been given.

Top Drugs

Author : Jie Jack Li
Publisher : Oxford University Press
Page : 240 pages
File Size : 41,9 Mb
Release : 2015-07-31
Category : Medical
ISBN : 9780199362592

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Top Drugs by Jie Jack Li Pdf

Drugs like Lipitor, Plavix, Taxol, and Zoloft are integral in today's medicinal world. These widely used products save lives and improve the quality of lives, playing a crucial role in everything from cholesterol management to cancer treatment. These advances in medicine were brought into existence after nuanced process of creation, featuring a wide range of chemical and pharmacological experimentation and discovery. Top Drugs: Their History, Pharmacology, and Synthesis provides an in-depth study on ten prominent drugs, outlining the chemistry behind each one's creation. Jie Jack Li, a medicinal chemist and an expert on drug discovery, offers a thorough analysis of the landscape of current drug development. The comprehensive text is divided by health issues, including cardiovascular, cancer, metabolic diseases, and infectious diseases. Each section features individual chapters on significant drugs, outlining the chemistry and history of the drug's discovery. Li begins each chapter with the product's history, providing necessary context. Li then proceeds to describe the mechanism of action, structure-activity relationship (SAR), bioavailability, metabolism, toxicology, the discovery route, and the process route. Top Drugs: Their History, Pharmacology, and Synthesis will acclimate students, scientists, and interested laypersons to the world of chemistry and drug discovery.

Pihkal

Author : Alexander Theodore Shulgin,Ann Shulgin
Publisher : Unknown
Page : 1012 pages
File Size : 48,7 Mb
Release : 1991
Category : Biochemistry
ISBN : 0963009605

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Pihkal by Alexander Theodore Shulgin,Ann Shulgin Pdf

PIHKAL (Phenethylamines I Have Known And Loved) is a unique book written by renowned psychopharmacologist Alexander Shulgin and his wife Ann Shulgin. This book gives details of their research and investigations into the use of psychedelic drugs for the study of the human mind, and is also a love story. The second half of the book describes in detail a wealth of phenethlyamines, their physical properties, dosages used, duration of effects observed, and commentary on effects.