The Age Of Fentanyl

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The Age of Fentanyl

Author : Brodie Ramin
Publisher : Dundurn
Page : 248 pages
File Size : 40,6 Mb
Release : 2020-03-14
Category : Medical
ISBN : 9781459746725

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The Age of Fentanyl by Brodie Ramin Pdf

Ottawa Book Award 2021 — Shortlisted • The Donner Prize 2020 — Shortlisted • Speaker's Book Award 2020 — Shortlisted Is there a way to end North America’s opioid epidemic? “A fascinating, wise, and humane analysis of one of the most pressing health challenges of the 21st century.” — Steven Pinker, author of Enlightenment Now In The Age of Fentanyl, Brodie Ramin tells the story of the opioid crisis, showing us the disease and cure from his perspective as an addiction doctor working on the front lines. We meet his patients, hear from other addiction experts, and learn about the science and medicine of opioid addiction and its treatments. He shows us how addiction can be prevented, how knowledge can reduce stigma, and how epidemics can be beaten. Dr. Ramin brings the hopeful message that just as patients and health care workers rallied together to fight HIV one generation ago, a coalition of patients, advocates, scientists, doctors, and nurses is once again finding solutions and making plans to stem the overdose deaths, block the spread of fentanyl, and end the epidemic.

The Age of Fentanyl

Author : Brodie Ramin
Publisher : Dundurn
Page : 232 pages
File Size : 43,6 Mb
Release : 2020-03-14
Category : Medical
ISBN : 9781459746718

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The Age of Fentanyl by Brodie Ramin Pdf

Dr. Brodie Ramin brings the story of the opioid epidemic into the era of fentanyl, which is the leading cause of overdose death in North America. From his perspective as an addiction doctor working on the front lines of the epidemic, Dr. Ramin discusses the disease and the cure.

The Least of Us

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
Page : 433 pages
File Size : 48,9 Mb
Release : 2021-11-02
Category : Social Science
ISBN : 9781635574371

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The Least of Us by Sam Quinones Pdf

Apple Best Books of 2021 Longlisted for the Andrew Carnegie Medal * Shortlisted for the Zocalo Book Prize From the New York Times bestselling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair. Sam Quinones traveled from Mexico to main streets across the U.S. to create Dreamland, a groundbreaking portrait of the opioid epidemic that awakened the nation. As the nation struggled to put back the pieces, Quinones was among the first to see the dangers that lay ahead: synthetic drugs and a new generation of kingpins whose product could be made in Magic Bullet blenders. In fentanyl, traffickers landed a painkiller a hundred times more powerful than morphine. They laced it into cocaine, meth, and counterfeit pills to cause tens of thousands of deaths-at the same time as Mexican traffickers made methamphetamine cheaper and more potent than ever, creating, Sam argues, swaths of mental illness and a surge in homelessness across the United States. Quinones hit the road to investigate these new threats, discovering how addiction is exacerbated by consumer-product corporations. “In a time when drug traffickers act like corporations and corporations like traffickers,” he writes, “our best defense, perhaps our only defense, lies in bolstering community.” Amid a landscape of despair, Quinones found hope in those embracing the forgotten and ignored, illuminating the striking truth that we are only as strong as our most vulnerable. Weaving analysis of the drug trade into stories of humble communities, The Least of Us delivers an unexpected and awe-inspiring response to the call that shocked the nation in Sam Quinones's award-winning Dreamland.

Pain Management and the Opioid Epidemic

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Page : 483 pages
File Size : 45,8 Mb
Release : 2017-09-28
Category : Medical
ISBN : 9780309459570

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Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Fentanyl, Inc.

Author : Ben Westhoff
Publisher : Atlantic Monthly Press
Page : 365 pages
File Size : 40,9 Mb
Release : 2019-09-03
Category : Business & Economics
ISBN : 9780802147950

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Fentanyl, Inc. by Ben Westhoff Pdf

A four-year investigation into the world of synthetic drugs—from black market factories to users & dealers to harm reduction activists—and what it revealed. A deeply human story, Fentanyl, Inc. is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. “A whole new crop of chemicals is radically changing the recreational drug landscape,” writes Ben Westhoff. “These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs” —and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice—and those with arcane acronyms like 25i-NBOMe—were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs’ effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China’s vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the United States and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many. “Timely and agonizing. . . . An impressive work of investigative journalism.” —USA Today “Westhoff explores the many-tentacled world of illicit opioids, from the streets of East St. Louis to Chinese pharmaceutical companies, from music festivals deep in the Michigan woods to sanctioned ‘shooting up rooms’ in Barcelona, in this frank, insightful, and occasionally searing exposé. . . . Westhoff’s well-reported and researched work will likely open eyes, slow knee-jerk responses, and start much needed conversations.” —Publishers Weekly “Our 25 Favorite Books of 2019” —St. Louis Post-Dispatch “Best Books of 2019” —Buzzfeed “Best Nonfiction of 2019” —Kirkus Reviews “50 Best Books of 2019” —Daily Telegraph “Best Nonfiction Books of 2019” —Tyler Cowen “Best Books of 2019” —Yahoo Finance

Medications for Opioid Use Disorder Save Lives

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
Publisher : National Academies Press
Page : 175 pages
File Size : 50,8 Mb
Release : 2019-06-16
Category : Medical
ISBN : 9780309486484

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Medications for Opioid Use Disorder Save Lives by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder Pdf

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

The Perfect Medicine

Author : Brodie Ramin
Publisher : Dundurn
Page : 226 pages
File Size : 49,7 Mb
Release : 2021-08-10
Category : Health & Fitness
ISBN : 9781459748224

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The Perfect Medicine by Brodie Ramin Pdf

Ottawa Book Award 2022 — Shortlisted Imagine a medicine that could make you live longer, healthier, happier, and stronger. What if that medicine was already right at your feet? Running is the miracle drug that can do all this and more — it is the perfect medicine. Throughout his career, Dr. Brodie Ramin has seen cases of diabetes, hypertension, and anxiety, which he has traced back to inactivity. Now more than ever, people are looking for inspiration and motivation to get fit, change their lives, and improve their overall wellness. In The Perfect Medicine, Dr. Ramin shares with us his discovery that we already have the perfect medicine to treat and prevent these common illnesses and improve our health: running. However, too few people are taking the right dose or using it at all. The Perfect Medicine explores the science of running and exercise and provides advice on how to maximize its benefits and be your best self. After rediscovering the joy of running in his early thirties, Dr. Ramin became fascinated by the activity. This book takes the reader on a personal journey of discovery, traces the evolution of running, shares strategies to get fit and run faster, and shows how exercise can even help people recover from addiction and mental health conditions.

Pain Killer

Author : Barry Meier
Publisher : Random House
Page : 241 pages
File Size : 42,8 Mb
Release : 2018-05-29
Category : Medical
ISBN : 9780525511090

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Pain Killer by Barry Meier Pdf

From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.

American Overdose

Author : Chris McGreal
Publisher : PublicAffairs
Page : 381 pages
File Size : 49,9 Mb
Release : 2018-11-13
Category : Social Science
ISBN : 9781541773776

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American Overdose by Chris McGreal Pdf

A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

The Future of Fentanyl and Other Synthetic Opioids

Author : Bryce Pardo,Jirka Taylor,Jonathan P. Caulkins,Beau Kilmer,Peter Reuter,Bradley D. Stein
Publisher : Unknown
Page : 0 pages
File Size : 46,9 Mb
Release : 2019
Category : Medical
ISBN : 1977403387

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The Future of Fentanyl and Other Synthetic Opioids by Bryce Pardo,Jirka Taylor,Jonathan P. Caulkins,Beau Kilmer,Peter Reuter,Bradley D. Stein Pdf

Deaths involving synthetic opioids, such as fentanyl, increased from roughly 3,000 in 2013 to more than 30,000 in 2018. This book provides readers with insights intended to improve their understanding of the synthetic opioid problem.

Dreamland (YA edition)

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
Page : 225 pages
File Size : 44,7 Mb
Release : 2019-07-16
Category : Juvenile Nonfiction
ISBN : 9781547601417

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Dreamland (YA edition) by Sam Quinones Pdf

As an adult book, Sam Quinones's Dreamland took the world by storm, winning the NBCC Award for General Nonfiction and hitting at least a dozen Best Book of the Year lists. Now, adapted for the first time for a young adult audience, this compelling reporting explains the roots of the current opiate crisis. In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital center of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America. How that happened is the riveting story of Dreamland. Quinones explains how the rise of the prescription drug OxyContin, a miraculous and extremely addictive painkiller pushed by pharmaceutical companies, paralleled the massive influx of black tar heroin--cheap, potent, and originating from one small county on Mexico's west coast, independent of any drug cartel. Introducing a memorable cast of characters--pharmaceutical pioneers, young Mexican entrepreneurs, narcotics investigators, survivors, teens, and parents--Dreamland is a revelatory account of the massive threat facing America and its heartland.

The Essence of Analgesia and Analgesics

Author : Raymond S. Sinatra,Jonathan S. Jahr,J. Michael Watkins-Pitchford
Publisher : Cambridge University Press
Page : 128 pages
File Size : 41,9 Mb
Release : 2010-10-14
Category : Medical
ISBN : 9781139491983

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The Essence of Analgesia and Analgesics by Raymond S. Sinatra,Jonathan S. Jahr,J. Michael Watkins-Pitchford Pdf

The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Training Manual for Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings

Author : Anonim
Publisher : Wpro Publication
Page : 0 pages
File Size : 50,5 Mb
Release : 2009
Category : Business & Economics
ISBN : 9290614315

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Training Manual for Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings by Anonim Pdf

"Companion v. to the WHO clinical guidelines for withdrawal management and treatment of drug dependence in closed settings" --P. vii.

The Thursday Murder Club

Author : Richard Osman
Publisher : Penguin
Page : 370 pages
File Size : 49,7 Mb
Release : 2020-09-22
Category : Fiction
ISBN : 9781984880970

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The Thursday Murder Club by Richard Osman Pdf

A New York Times bestseller | Soon to be a major motion picture from Steven Spielberg at Amblin Entertainment “Witty, endearing and greatly entertaining.” —Wall Street Journal “Don’t trust anyone, including the four septuagenarian sleuths in Osman’s own laugh-out-loud whodunit.” —Parade Four septuagenarians with a few tricks up their sleeves A female cop with her first big case A brutal murder Welcome to... THE THURSDAY MURDER CLUB In a peaceful retirement village, four unlikely friends meet weekly in the Jigsaw Room to discuss unsolved crimes; together they call themselves the Thursday Murder Club. When a local developer is found dead with a mysterious photograph left next to the body, the Thursday Murder Club suddenly find themselves in the middle of their first live case. As the bodies begin to pile up, can our unorthodox but brilliant gang catch the killer, before it's too late?