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Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 624 pages
File Size : 48,5 Mb
Release : 2011-08-09
Category : History
ISBN : 9781439170915
"This edition includes a new interview with the author"--P. [4] of cover.
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 96 pages
File Size : 42,6 Mb
Release : 2015-10-13
Category : Medical
ISBN : 9781476784854
Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 624 pages
File Size : 40,8 Mb
Release : 2016-05-17
Category : Medical
ISBN : 9781476733531
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 496 pages
File Size : 51,8 Mb
Release : 2022-10-25
Category : Medical
ISBN : 9781982117375
Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize! Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more! In The Song of the Cell, the extraordinary author of the Pulitzer Prize–winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” (Oprah Daily). Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them “cells.” The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human. “In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” (The New Yorker).
Author : Azra Raza
Publisher : Basic Books
Page : 368 pages
File Size : 40,8 Mb
Release : 2019-10-15
Category : Health & Fitness
ISBN : 9781541699502
With the fascinating scholarship of The Emperor of All Maladies and the deeply personal experience of When Breath Becomes Air, a world-class oncologist examines the current state of cancer and its devastating impact on the individuals it affects -- including herself. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.
Author : David Rieff
Publisher : Simon and Schuster
Page : 201 pages
File Size : 48,7 Mb
Release : 2008-01-08
Category : Biography & Autobiography
ISBN : 9781416554288
Both a memoir and an investigation, Swimming in a Sea of Death is David Rieff's loving tribute to his mother, the writer Susan Sontag, and her final battle with cancer. Rieff's brave, passionate, and unsparing witness of the last nine months of her life, from her initial diagnosis to her death, is both an intensely personal portrait of the relationship between a mother and a son, and a reflection on what it is like to try to help someone gravely ill in her fight to go on living and, when the time comes, to die with dignity. Rieff offers no easy answers. Instead, his intensely personal book is a meditation on what it means to confront death in our culture. In his most profound work, this brilliant writer confronts the blunt feelings of the survivor -- the guilt, the self-questioning, the sense of not having done enough. And he tries to understand what it means to desire so desperately, as his mother did to the end of her life, to try almost anything in order to go on living. Drawing on his mother's heroic struggle, paying tribute to her doctors' ingenuity and faithfulness, and determined to tell what happened to them all, Swimming in a Sea of Death subtly draws wider lessons that will be of value to others when they find themselves in the same situation.
Author : Atul Gawande
Publisher : Metropolitan Books
Page : 304 pages
File Size : 45,8 Mb
Release : 2014-10-07
Category : Social Science
ISBN : 9781627790550
#1 New York Times Bestseller In Being Mortal, bestselling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering. Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified. Full of eye-opening research and riveting storytelling, Being Mortal asserts that medicine can comfort and enhance our experience even to the end, providing not only a good life but also a good end.
Author : Tony Judt
Publisher : Penguin
Page : 137 pages
File Size : 49,6 Mb
Release : 2010-11-11
Category : Biography & Autobiography
ISBN : 9781101484012
A New York Times Book Review Notable Book of the Year “[A] tremendously moving memorial to a first-class historian and essayist . . . humane, fearless, unsparingly honest.” —The Financial Times “[A] memorable collection from a memorable man.” —BookPage "It might be thought the height of poor taste to ascribe good fortune to a healthy man with a young family struck down at the age of sixty by an incurable degenerative disorder from which he must shortly die. But there is more than one sort of luck. To fall prey to a motor neuron disease is surely to have offended the Gods at some point, and there is nothing more to be said. But if you must suffer thus, better to have a well-stocked head." —Tony Judt The Memory Chalet is a memoir unlike any you have ever read before. Each essay charts some experience or remembrance of the past through the sieve of Tony Judt's prodigious mind. His youthful love of a particular London bus route evolves into a reflection on public civility and interwar urban planning. Memories of the 1968 student riots of Paris meander through the divergent sex politics of Europe, before concluding that his generation "was a revolutionary generation, but missed the revolution." A series of road trips across America lead not just to an appreciation of American history, but to an eventual acquisition of citizenship. Foods and trains and long-lost smells all compete for Judt's attention; but for us, he has forged his reflections into an elegant arc of analysis. All as simply and beautifully arranged as a Swiss chalet-a reassuring refuge deep in the mountains of memory.
Author : Andrew Solomon
Publisher : Simon and Schuster
Page : 576 pages
File Size : 48,8 Mb
Release : 2014-09-16
Category : Biography & Autobiography
ISBN : 9781451611038
The author offers a look at depression, drawing on his own battle with the illness and interviews with fellow sufferers, researchers, and doctors to assess the disease's complexities, causes, symptoms, and available therapies.
Author : Jonathan Weiner
Publisher : Harper Collins
Page : 322 pages
File Size : 51,5 Mb
Release : 2010-06-22
Category : Science
ISBN : 9780062000217
“[A] searching and surprisingly witty look at the scientific odds against tomorrow.” —Timothy Ferris Jonathan Weiner—winner of the Pulitzer Prize, the National Book Critics Circle Award, and the Los Angeles Times Book Prize, and one of the most distinguished popular science writers in America—examines “the strange science of immortality” in Long for This World. A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?
Author : Ron Hall,Denver Moore
Publisher : Thomas Nelson
Page : 254 pages
File Size : 53,8 Mb
Release : 2008-03-09
Category : Biography & Autobiography
ISBN : 9781418525651
A critically acclaimed #1 New York Times best-seller with more than one million copies in print! Now a major motion picture. Gritty with pain, betrayal, and brutality, this incredible true story also shines with an unexpected, life-changing love. Meet Denver, raised under plantation-style slavery in Louisiana until he escaped the “Man” in the 1960’s by hopping a train. Untrusting, uneducated, and violent, he spends 18 years on the streets of Dallas and Fort Worth. Meet Ron Hall, a self-made millionaire in the world of high-priced deals—an international arts dealer who moves between upscale New York galleries and celebrities. It seems unlikely that these two men would meet under normal circumstances, but when Deborah Hall, Ron's wife, meets Denver, she sees him through God's eyes of compassion. When Deborah is diagnosed with cancer, she charges Ron with the mission of helping Denver. From this request, an extraordinary friendship forms between Denver and Ron, changing them both forever. A tale told in two unique voices, Same Kind of Different as Me weaves two completely different life experiences into one common journey. There is pain and laughter, doubt and tears, and in the end a triumphal story that readers will never forget. Continue this story of friendship in What Difference Do It Make?: Stories of Hope and Healing, available now. Same Kind of Different as Me also is available in Spanish.
Author : Devra Davis
Publisher : Basic Books
Page : 528 pages
File Size : 42,9 Mb
Release : 2007-11-20
Category : Science
ISBN : 9780465010318
The War on Cancer set out to find, treat, and cure a disease. Left untouched were many of the things known to cause cancer, including tobacco, the workplace, radiation, or the global environment. Proof of how the world in which we live and work affects whether we get cancer was either overlooked or suppressed. This has been no accident. The War on Cancer was run by leaders of industries that made cancer-causing products, and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies-a legacy that persists to this day. This is the gripping story of a major public health effort diverted and distorted for private gain. A portion of the profits from this book will go to support research on cancer prevention.
Author : Frank Vertosick
Publisher : W. W. Norton & Company
Page : 272 pages
File Size : 51,7 Mb
Release : 2008-03-17
Category : Medical
ISBN : 9780393344028
The story of one man's evolution from naive and ambitious young intern to world-class neurosurgeon. With poignant insight and humor, Frank Vertosick Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick’s patients and unsparing yet fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain—the culmination of decades spent struggling to learn an unforgiving craft—illuminates both the mysteries of the mind and the realities of the operating room.
Author : Archie Brown
Publisher : Basic Books
Page : 482 pages
File Size : 51,7 Mb
Release : 2014-04-08
Category : Political Science
ISBN : 9780465080977
From one of the world's preeminent political historians, a magisterial study of political leadership around the world from the advent of parliamentary democracy to the age of Obama. All too frequently, leadership is reduced to a simple dichotomy: the strong versus the weak. Yet, there are myriad ways to exercise effective political leadership -- as well as different ways to fail. We blame our leaders for economic downfalls and praise them for vital social reforms, but rarely do we question what makes some leaders successful while others falter. In this magisterial and wide-ranging survey of political leadership over the past hundred years, renowned Oxford politics professor Archie Brown challenges the widespread belief that strong leaders -- meaning those who dominate their colleagues and the policy-making process -- are the most successful and admirable. In reality, only a minority of political leaders will truly make a lasting difference. Though we tend to dismiss more collegial styles of leadership as weak, it is often the most cooperative leaders who have the greatest impact. Drawing on extensive research and decades of political analysis and experience, Brown illuminates the achievements, failures and foibles of a broad array of twentieth century politicians. Whether speaking of redefining leaders like Franklin Delano Roosevelt, Lyndon Johnson, and Margaret Thatcher, who expanded the limits of what was politically possible during their time in power, or the even rarer transformational leaders who played a decisive role in bringing about systemic change -- Charles de Gaulle, Mikhail Gorbachev and Nelson Mandela, among them -- Brown challenges our commonly held beliefs about political efficacy and strength. Overturning many of our assumptions about the twentieth century's most important figures, Brown's conclusions are both original and enlightening. The Myth of the Strong Leader compels us to reassess the leaders who have shaped our world - and to reconsider how we should choose and evaluate those who will lead us into the future.
Author : Dr. Euan Angus Ashley
Publisher : Celadon Books
Page : 221 pages
File Size : 45,6 Mb
Release : 2021-02-23
Category : Science
ISBN : 9781250234971
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.