The Emperor Of All Maladies By Siddhartha Mukherjee
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The Emperor of All Maladies Book in PDF, Epub and Kindle
An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.
The Emperor of All Maladies Book in PDF, Epub and Kindle
Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Contemporary Physician-Authors Book in PDF, Epub and Kindle
This book examines the phenomenon of physician-authors. Focusing on the books that contemporary doctors write--the stories that they tell--with contributors critically engaging their work. A selection of original chapters from leading scholars in medical and health humanities analyze the literary output of doctors, including Oliver Sacks, Danielle Ofri, Atul Gawande, Louise Aronson, Siddhartha Mukherjee, and Abraham Verghese. Discussing issues of moral meaning in the works of contemporary doctor-writers, from memoir to poetry, this collection reflects some of the diversity of medicine today. A key reference for all students and scholars of medical and health humanities, the book will be especially useful for those interested in the relationship between literature and practising medicine.
“[A] searching and surprisingly witty look at the scientific odds against tomorrow.” —Timothy Ferris Jonathan Weiner—winner of the Pulitzer Prize, the National Book Critics Circle Award, and the Los Angeles Times Book Prize, and one of the most distinguished popular science writers in America—examines “the strange science of immortality” in Long for This World. A fast-paced, sure-to-astonish scientific adventure from “one of our finest science journalists” (Jonah Lehrer), Weiner’s Long for This World addresses the ageless question, “Is there a secret to eternal youth?” And has it, at long last, been found?
'As big a topic as life itself; I'm not sure a writer could cover it better' The Times From the prize-winning author of The Emperor of All Maladies, The Song of the Cell tells the vivid, thrilling and suspenseful story of the fundamental unit of life. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that alters both biology and medicine forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves, are built from these compartments. Hooke christens them 'cells'. The discovery of cells announced the birth of a new kind of medicine. A hip fracture, a cardiac arrest, Alzheimer's, AIDS, lung cancer - all could be re-conceived as the results of cells, or a cellular ecosystem, functioning abnormally. And all could be treated by therapeutic manipulations of cells. This revolution in cell biology is still in progress: it represents one of the most significant advances in science and medicine. Both panoramic and intimate, this is Siddhartha Mukherjee's most spectacular book yet. 'Brilliant ... medical magic' Daily Telegraph **A MAIL ON SUNDAY AND GUARDIAN BOOK OF THE YEAR**
Swimming in a Sea of Death Book in PDF, Epub and Kindle
Both a memoir and an investigation, Swimming in a Sea of Death is David Rieff's loving tribute to his mother, the writer Susan Sontag, and her final battle with cancer. Rieff's brave, passionate, and unsparing witness of the last nine months of her life, from her initial diagnosis to her death, is both an intensely personal portrait of the relationship between a mother and a son, and a reflection on what it is like to try to help someone gravely ill in her fight to go on living and, when the time comes, to die with dignity. Rieff offers no easy answers. Instead, his intensely personal book is a meditation on what it means to confront death in our culture. In his most profound work, this brilliant writer confronts the blunt feelings of the survivor -- the guilt, the self-questioning, the sense of not having done enough. And he tries to understand what it means to desire so desperately, as his mother did to the end of her life, to try almost anything in order to go on living. Drawing on his mother's heroic struggle, paying tribute to her doctors' ingenuity and faithfulness, and determined to tell what happened to them all, Swimming in a Sea of Death subtly draws wider lessons that will be of value to others when they find themselves in the same situation.
WINNER OF THE 2020 PULITZER PRIZE IN GENERAL NONFICTION "The Undying is a startling, urgent intervention in our discourses about sickness and health, art and science, language and literature, and mortality and death. In dissecting what she terms 'the ideological regime of cancer,' Anne Boyer has produced a profound and unforgettable document on the experience of life itself." —Sally Rooney, author of Normal People "Anne Boyer’s radically unsentimental account of cancer and the 'carcinogenosphere' obliterates cliche. By demonstrating how her utterly specific experience is also irreducibly social, she opens up new spaces for thinking and feeling together. The Undying is an outraged, beautiful, and brilliant work of embodied critique." —Ben Lerner, author of The Topeka School A week after her forty-first birthday, the acclaimed poet Anne Boyer was diagnosed with highly aggressive triple-negative breast cancer. For a single mother living paycheck to paycheck who had always been the caregiver rather than the one needing care, the catastrophic illness was both a crisis and an initiation into new ideas about mortality and the gendered politics of illness. A twenty-first-century Illness as Metaphor, as well as a harrowing memoir of survival, The Undying explores the experience of illness as mediated by digital screens, weaving in ancient Roman dream diarists, cancer hoaxers and fetishists, cancer vloggers, corporate lies, John Donne, pro-pain ”dolorists,” the ecological costs of chemotherapy, and the many little murders of capitalism. It excoriates the pharmaceutical industry and the bland hypocrisies of ”pink ribbon culture” while also diving into the long literary line of women writing about their own illnesses and ongoing deaths: Audre Lorde, Kathy Acker, Susan Sontag, and others. A genre-bending memoir in the tradition of The Argonauts, The Undying will break your heart, make you angry enough to spit, and show you contemporary America as a thing both desperately ill and occasionally, perversely glorious. Includes black-and-white illustrations
In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must. A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukaemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.
A New York Times Book Review Notable Book of the Year “[A] tremendously moving memorial to a first-class historian and essayist . . . humane, fearless, unsparingly honest.” —The Financial Times “[A] memorable collection from a memorable man.” —BookPage "It might be thought the height of poor taste to ascribe good fortune to a healthy man with a young family struck down at the age of sixty by an incurable degenerative disorder from which he must shortly die. But there is more than one sort of luck. To fall prey to a motor neuron disease is surely to have offended the Gods at some point, and there is nothing more to be said. But if you must suffer thus, better to have a well-stocked head." —Tony Judt The Memory Chalet is a memoir unlike any you have ever read before. Each essay charts some experience or remembrance of the past through the sieve of Tony Judt's prodigious mind. His youthful love of a particular London bus route evolves into a reflection on public civility and interwar urban planning. Memories of the 1968 student riots of Paris meander through the divergent sex politics of Europe, before concluding that his generation "was a revolutionary generation, but missed the revolution." A series of road trips across America lead not just to an appreciation of American history, but to an eventual acquisition of citizenship. Foods and trains and long-lost smells all compete for Judt's attention; but for us, he has forged his reflections into an elegant arc of analysis. All as simply and beautifully arranged as a Swiss chalet-a reassuring refuge deep in the mountains of memory.
#1 New York Times Bestseller In Being Mortal, bestselling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering. Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified. Full of eye-opening research and riveting storytelling, Being Mortal asserts that medicine can comfort and enhance our experience even to the end, providing not only a good life but also a good end.
The Best American Science and Nature Writing 2013 Book in PDF, Epub and Kindle
Twenty-seven of America’s best science and nature essays of 2013, selected by the author of The Emperor of All Maladies and the #1 New York Times bestseller, The Gene. Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields. The Best American Science & Nature Writing 2013 includes: “The T-Cell Army” by Jerome Groopman “The Artificial Leaf” by David Owen “The Life of Pi, and Other Infinities” by Natalie Angier “Altered States” by Oliver Sacks “Recall of the Wild” by Elizabeth Kolbert “Super Humanity” by Robert M. Sapolsky “Can a Jellyfish Unlock the Secret of Immortality?” by Nathaniel Rich Contributors also include: J. B. Mackinnon · Benjamin Hale · Tim Zimmermann · David Deutsch and Artur Ekert · Michael Moyer · Sylvia A. Earle · John Pavlus · Michelle Nijhuis · Rick Bass · Michael Specter · Alan Lightman · David Quammen · Keith Gessen · Steven Weinberg · Gareth Cook · Katherine Harmon · Stephen Marche · Mark Bowden · Kevin Dutton
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.