Carcinoma Of The Prostate

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 41,7 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz
Publisher : Walter de Gruyter
Page : 220 pages
File Size : 54,5 Mb
Release : 2013-05-22
Category : Medical
ISBN : 9783110807271

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Molecular Biology of Prostate Cancer by Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz Pdf

Author : Michel Bolla,Hendrik van Poppel
Publisher : Springer
Page : 422 pages
File Size : 45,5 Mb
Release : 2017-01-09
Category : Medical
ISBN : 9783319427690

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Management of Prostate Cancer by Michel Bolla,Hendrik van Poppel Pdf

This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors. The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT. The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.

Author : Jens E. Altwein,Peter Faul,Wolfgang Schneider
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642761294

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Incidental Carcinoma of the Prostate by Jens E. Altwein,Peter Faul,Wolfgang Schneider Pdf

One out of every two men over eigthy suffers from carcinoma of the prostate.It is discovered incidentally in many patients with an alleged benign prostatic hyperplasia. In treating patients, the authors make clear that primary radical prostatectomy is preferred over transurethral resection due to the lower complication rate.

Author : Scott M. Dehm,Donald J. Tindall
Publisher : Springer Nature
Page : 483 pages
File Size : 41,8 Mb
Release : 2020-01-03
Category : Medical
ISBN : 9783030326562

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Prostate Cancer by Scott M. Dehm,Donald J. Tindall Pdf

The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.

Author : Andrew W. Bruce,John Trachtenberg
Publisher : Springer Science & Business Media
Page : 225 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447113980

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Adenocarcinoma of the Prostate by Andrew W. Bruce,John Trachtenberg Pdf

Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.

Author : G. Raspé,W. Brosig
Publisher : Elsevier
Page : 220 pages
File Size : 52,9 Mb
Release : 2013-10-22
Category : Health & Fitness
ISBN : 9781483187112

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International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, November 13 to 15, 1969 by G. Raspé,W. Brosig Pdf

International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, November 13 to 15, 1969 presents a resolution to the doubts and uncertainty in the treatment of carcinoma and formulate a new policy for handling. It discusses the basis of hormonal treatment of prostatic cancer. The focus of study is the pharmacological aspects of prostate cancer treatment. Some of the topics covered in the book are the metabolism of testosterone in the prostate, the use of stilbestrol diphosphate in treating prostate cancer, the pathology of prostate cancer, and the cardiovascular complications of the disease. The subjects on orchiectomy and adrenalectomy are covered. The modern radiotherapy is discussed. The text identifies the use of radioactive isotopes. An analysis of the irradiation of the hypophysis is presented. A chapter of the volume is devoted to the cytotoxic agents in prostate carcinoma treatment. Another section of the book focuses on application of cryo-therapy. The book will provide useful information to doctors, oncologists, radiologists, students and researchers.

Author : Zbigniew Petrovich,Luc Baert,Luther W. Brady
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 55,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642609565

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Carcinoma of the Prostate by Zbigniew Petrovich,Luc Baert,Luther W. Brady Pdf

The American Cancer Society anticipates that during 1995, 244000 new cases of cancer of the prostate will have been diagnosed in the United States, with 40400 deaths from the disease process. The rapid increase in the actual number of new cases in the United States is directly related to more regularized digital rectal examinations and the more frequent and widespread use of prostate-specific antigen (PSA) screening programs. As a conse quence, major controversies have emerged in how best to manage the patient with cancer of the prostate. These include the necessity of PSA screening programs, how to interpret PSA values, what imaging studies are most appropriate for definition of the true extent of the disease process, the value of pretreatment surgical staging of the disease process, and the value of different treatments. The latter encompass a wide range of options: observa tion, radical prostatectomy, the Walsh-type prostatectomy procedure, definitive external beam radiation therapy, local interstitial implantation using iodine-125, iridium-l92, or palladium-103, orchiectomy, cryosurgery, hyperthermia, and various antitestosterone agents such as estrogens or LH,RH agonists. The present volume deals with the major parameters of controversy with regard to cancer of the prostate and will enable the reader to acquire a better understanding of the disease and how best it might be managed to achieve an optimal outcome with a minimum of complications.

Author : Leland W. K. Chung,William B. Isaacs,Jonathan W. Simons
Publisher : Springer Science & Business Media
Page : 508 pages
File Size : 46,7 Mb
Release : 2007-11-10
Category : Medical
ISBN : 9781597452243

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Prostate Cancer by Leland W. K. Chung,William B. Isaacs,Jonathan W. Simons Pdf

Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

Author : Jack Cuzick,Mangesh A. Thorat
Publisher : Springer Science & Business Media
Page : 167 pages
File Size : 44,8 Mb
Release : 2014-02-15
Category : Medical
ISBN : 9783642451959

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Prostate Cancer Prevention by Jack Cuzick,Mangesh A. Thorat Pdf

Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

Author : Ashutosh Tewari
Publisher : Springer Science & Business Media
Page : 1110 pages
File Size : 41,5 Mb
Release : 2013-04-05
Category : Medical
ISBN : 9781447128649

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Prostate Cancer: A Comprehensive Perspective by Ashutosh Tewari Pdf

Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.

Author : Hans-Peter Schmid
Publisher : Springer Science & Business Media
Page : 81 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642854309

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The clinically organ-confined adenocarcinoma of the prostate by Hans-Peter Schmid Pdf

Dr. Hans-Peter Schmid has addressed in this monograph the basic dilemmas surrounding prostate cancer. These dilemmas include the 40 % histologic incidence of invasive cancer in men in comparison to a 3 % death rate, the extraordinary slow doubling time of four to five years for untreated early clinical stages (T1 and T2 cancers), the limited life span of even healthy men over 70 years of age, and the national and international debates of how to treat this cancer. It is important, however, to recognize that despite these uncertainties, prostate cancer is probably the most predictive of all human solid tumors. Dr. Schmid has addressed the basis for much of this predictability in this monograph. The level of serum PSA and its rate of increase in the untreated patient with a prostate size of less than 50 grams is undoub tedly the most useful of all measurements in predicting volume and grade of the cancer, but it is closely followed by assessment of the extent and percent of grade 4 and 5 cancer in six systematic, spatially separated biopsies. Estimating the amount of suspected cancer on digital rectal examination by assigning a clinical stage is useful, but far less quantitative than PSA and systematic biopsies. The Basel series in this monograph adds strong support to these basic concepts. April 1994 ThomasA. Stamey, M. D. Professor and Chairman Department of Urology Stanford University School of Medicine Stanford, California, USA v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V I. 1 Introduction and overview . . . . . . . . . . . . . . . . . . . . . . . . . . .

Author : Mahul B. Amin,John Eble,David Grignon,John Srigley
Publisher : Lippincott Williams & Wilkins
Page : 2443 pages
File Size : 49,6 Mb
Release : 2013-11-14
Category : Medical
ISBN : 9781469857961

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Urological Pathology by Mahul B. Amin,John Eble,David Grignon,John Srigley Pdf

Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!

Author : Antonio Lopez-Beltran,Liang Cheng,Maria Rosaria Raspollini,Rodolfo Montironi
Publisher : Cambridge University Press
Page : 225 pages
File Size : 53,6 Mb
Release : 2017-11-30
Category : Medical
ISBN : 9781108185653

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Pathology of the Prostate by Antonio Lopez-Beltran,Liang Cheng,Maria Rosaria Raspollini,Rodolfo Montironi Pdf

A practical approach to pathology of the prostate with integrated algorithms using classic histopathology, representative images and relevant immunohistochemistry.

Author : Maria Rosaria Raspollini,Antonio Lopez-Beltran
Publisher : Cambridge University Press
Page : 433 pages
File Size : 44,7 Mb
Release : 2019-02-21
Category : Medical
ISBN : 9781107170452

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Gynecologic and Urologic Pathology by Maria Rosaria Raspollini,Antonio Lopez-Beltran Pdf

This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.