Classical Genetic Research And Its Legacy

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Classical Genetic Research and its Legacy

Author : Jean-Paul Gaudillière,Hans-Jörg Rheinberger
Publisher : Routledge
Page : 264 pages
File Size : 54,7 Mb
Release : 2004-10-07
Category : History
ISBN : 9781134334148

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Classical Genetic Research and its Legacy by Jean-Paul Gaudillière,Hans-Jörg Rheinberger Pdf

With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of mapping procedures as they were developed in classical genetics. An accompanying volume - From Molecular Genetics to Genomics - covers the history of molecular genetics and genomics. The book shows that the technology of genetic mapping is by no means a recent acquisition of molecular genetics or even genetic engineering. It demonstrates that the development of mapping technologies has accompanied the rise of modern genetics from its very beginnings. In Section One, Mendelian genetics is set in perspective from the viewpoint of the detection and description of linkage phenomena. Section Two addresses the role of mapping for the experimental working practice of classical geneticists, their social interactions and for the laboratory 'life worlds'. With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contibution to the history of genetics. A companion volume from the same editors - From Molecular Genetics to Genomics: The Mapping Cultures of Twentieth Century Genetics - covers the history of molecular genetics and genomics.

Classical Genetic Research and Its Legacy

Author : Benoit Godin
Publisher : Psychology Press
Page : 264 pages
File Size : 52,5 Mb
Release : 2004
Category : Gene mapping
ISBN : 0415328497

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Classical Genetic Research and Its Legacy by Benoit Godin Pdf

Governments and researchers from industrial countries have been measuring science and technology for more than seventy years. This book provides an historical examination of official science and technology statistics and indicators in Western countries and addresses the following questions: What were the main historical moments that led to the development of statistics on science and technology? What were the main socio-political stakes behind the activities of science measurement? What were the philosophical and ideological conceptions that drove measurement? What statistics and indicators were developed and how were they constructed? The first part of the book concentrates on the construction and development of science and technology statistics from 1930 to the present, the principles at work, and the vested interests and forces behind that construction. The second part analyzes to what uses statistics were put, and with how much confidence actors used statistics to document their case or to promote their political agenda.

Mendel's Legacy

Author : Elof Axel Carlson
Publisher : CSHL Press
Page : 364 pages
File Size : 51,6 Mb
Release : 2004
Category : Science
ISBN : 0879696753

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Mendel's Legacy by Elof Axel Carlson Pdf

This latest book by Elof Carlson (The Unfit) is a first history of classical genetics, the era in which the chromosome theory of heredity was proposed and developed. Highly illustrated and based heavily on early 20th century original sources, the book traces the roots of genetics in breeding analysis and studies of cytology, evolution, and reproductive biology that began in Europe but were synthesized in the United States through new Ph.D. programs and expanded academic funding. Carlson argues that, influenced largely by new technologies and instrumentation, the life sciences progressed though incremental change rather than paradigm shifts, and he describes how molecular biology emerged from the key ideas and model systems of classical genetics. Readable and original, this narrative will interest historians and science educators as well as today's practitioners of genetics.

From Molecular Genetics to Genomics

Author : Jean-Paul Gaudillière,Hans-Jörg Rheinberger
Publisher : Routledge
Page : 244 pages
File Size : 52,6 Mb
Release : 2004-10-07
Category : History
ISBN : 9781134334070

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From Molecular Genetics to Genomics by Jean-Paul Gaudillière,Hans-Jörg Rheinberger Pdf

With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity, and the organisation of genetic knowledge in maps has been a major driving force in the establishment of the discipline. This book provides a comprehensive history of molecular genetics and genomics. The first section of the book shows how the genetic cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms such as bacteria and through the invention of new experimental tools such as gene transfer. The second section addresses the moral and political economy of human genome sequencing in all its technical, epistemic, social and economic complexity. With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contribution to the history of genetics. A companion volume from the same editors - Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth Century Genetics - covers the history of mapping procedures as they were developed in classical genetics.

The Evolution of Genetics

Author : Arnold W. Ravin
Publisher : Unknown
Page : 128 pages
File Size : 43,6 Mb
Release : 2013
Category : Electronic
ISBN : 1483229556

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The Evolution of Genetics by Arnold W. Ravin Pdf

The Evolution of Genetics provides a review of the development of genetics. It is not intended as a history of the science of heredity. By a brief and general survey, however, it seeks to show the connections of past to present research, and of current discoveries to future investigations. The book opens with a chapter on the legacy of classical genetics. This is followed by separate chapters on the use of microorganisms in molecular genetics; the structure and replication of genetic material; mutation and recombination of genetic material; the heterocatalytic function of genetic material; and ...

Genetics

Author : Kepos Media, Inc
Publisher : Unknown
Page : 128 pages
File Size : 46,6 Mb
Release : 2018
Category : Genetics
ISBN : 1410380807

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Genetics by Kepos Media, Inc Pdf

This set explores the history, theory, technology, ethics, and uses (and misuses) of genetic knowledge. Topics span the field from classical genetics to molecular genetics to population genetics.

Blood Relations

Author : Jenny Bangham
Publisher : University of Chicago Press
Page : 353 pages
File Size : 42,9 Mb
Release : 2020-12-07
Category : Science
ISBN : 9780226740171

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Blood Relations by Jenny Bangham Pdf

Blood is messy, dangerous, and charged with meaning. By following it as it circulates through people and institutions, Jenny Bangham explores the intimate connections between the early infrastructures of blood transfusion and the development of human genetics. Focusing on mid-twentieth-century Britain, Blood Relations connects histories of eugenics to the local politics of giving blood, showing how the exchange of blood carved out networks that made human populations into objects of medical surveillance and scientific research. Bangham reveals how biology was transformed by two world wars, how scientists have worked to define racial categories, and how the practices and rhetoric of public health made genetics into a human science. Today, genetics is a powerful authority on human health and identity, and Blood Relations helps us understand how this authority was achieved.

A Cultural History of Heredity

Author : Staffan Müller-Wille,Hans-Jörg Rheinberger
Publisher : University of Chicago Press
Page : 339 pages
File Size : 52,9 Mb
Release : 2012-06-22
Category : Science
ISBN : 9780226545721

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A Cultural History of Heredity by Staffan Müller-Wille,Hans-Jörg Rheinberger Pdf

“Thought-provoking…any scientist interested in genetics will find this an enlightening look at the history of this field.”—Quarterly Review of Biology It was only around 1800 that heredity began to enter debates among physicians, breeders, and naturalists. Soon thereafter, it evolved into one of the most fundamental concepts of biology. Here, Staffan Muller-Wille and Hans-Jorg Rheinberger offer a succinct cultural history of the scientific concept of heredity. They outline the dramatic changes the idea has undergone since the early modern period and describe the political and technological developments that brought about these changes. They begin with an account of premodern theories of generation, showing that these were concerned with the procreation of individuals rather than with hereditary transmission, and reveal that when hereditarian thinking first emerged, it did so in a variety of cultural domains, such as politics and law, medicine, natural history, breeding, and anthropology. The authors then track theories of heredity from the late nineteenth century—when leading biologists considered it in light of growing societal concerns with race and eugenics—through the rise of classical and molecular genetics in the twentieth century, to today, as researchers apply sophisticated information technologies to understand heredity. What we come to see from this exquisite history is why it took such a long time for heredity to become a prominent concept in the life sciences, and why it gained such overwhelming importance in those sciences and the broader culture over the last two centuries.

From Molecular Genetics to Genomics

Author : Jean-Paul Gaudillière,Hans-Jörg Rheinberger
Publisher : Routledge
Page : 241 pages
File Size : 42,9 Mb
Release : 2004-10-07
Category : History
ISBN : 9781134334087

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From Molecular Genetics to Genomics by Jean-Paul Gaudillière,Hans-Jörg Rheinberger Pdf

With the rise of genomics, the life sciences have entered a new era. This book provides a comprehensive history of molecular genetics and genomics.

A History of Genetics

Author : Alfred Henry Sturtevant
Publisher : CSHL Press
Page : 190 pages
File Size : 55,8 Mb
Release : 2001
Category : Medical
ISBN : 0879696079

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A History of Genetics by Alfred Henry Sturtevant Pdf

In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.

Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society

Author : L.S. Parker,Rachel A. Ankeny
Publisher : Springer Science & Business Media
Page : 334 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401002691

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Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society by L.S. Parker,Rachel A. Ankeny Pdf

This volume employs philosophical and historical perspectives to shed light on classic social, ethical, and philosophical issues raised with renewed urgency against the backdrop of the mapping of the human genome. Philosophers and historians of science and medicine, ethicists, and those interested in the reciprocal influence of science and other cultural practices will find the arguments and observations offered fascinating and indispensable.

Review of the Department of Energy's Genomics: GTL Program

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program
Publisher : National Academies Press
Page : 102 pages
File Size : 44,8 Mb
Release : 2006-04-19
Category : Science
ISBN : 9780309180719

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Review of the Department of Energy's Genomics: GTL Program by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program Pdf

The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.

The Genealogical Science

Author : Nadia Abu El-Haj
Publisher : University of Chicago Press
Page : 328 pages
File Size : 50,5 Mb
Release : 2012-01-13
Category : Social Science
ISBN : 9780226201429

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The Genealogical Science by Nadia Abu El-Haj Pdf

The Genealogical Science analyzes the scientific work and social implications of the flourishing field of genetic history. A biological discipline that relies on genetic data in order to reconstruct the geographic origins of contemporary populations—their histories of migration and genealogical connections to other present-day groups—this historical science is garnering ever more credibility and social reach, in large part due to a growing industry in ancestry testing. In this book, Nadia Abu El-Haj examines genetic history’s working assumptions about culture and nature, identity and biology, and the individual and the collective. Through the example of the study of Jewish origins, she explores novel cultural and political practices that are emerging as genetic history’s claims and “facts” circulate in the public domain and illustrates how this historical science is intrinsically entangled with cultural imaginations and political commitments. Chronicling late-nineteenth- to mid-twentieth-century understandings of race, nature, and culture, she identifies continuities and shifts in scientific claims, institutional contexts, and political worlds in order to show how the meanings of biological difference have changed over time. In so doing she gives an account of how and why it is that genetic history is so socially felicitous today and elucidates the range of understandings of the self, individual and collective, this scientific field is making possible. More specifically, through her focus on the history of projects of Jewish self-fashioning that have taken place on the terrain of the biological sciences, The Genealogical Science analyzes genetic history as the latest iteration of a cultural and political practice now over a century old.

The Emergence of Genetic Rationality

Author : Phillip Thurtle
Publisher : University of Washington Press
Page : 392 pages
File Size : 43,6 Mb
Release : 2011-06-01
Category : Science
ISBN : 9780295990347

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The Emergence of Genetic Rationality by Phillip Thurtle Pdf

The emergence of genetic science has profoundly shaped how we think about biology. Indeed, it is difficult now to consider nearly any facet of human experience without first considering the gene. But this mode of understanding life is not, of course, transhistorical. Phillip Thurtle takes us back to the moment just before the emergence of genetic rationality at the turn of the twentieth century to explicate the technological, economic, cultural, and even narrative transformations necessary to make genetic thinking possible. The rise of managerial capitalism brought with it an array of homologous practices, all of which transformed the social fabric. With transformations in political economy and new technologies came new conceptions of biology, and it is in the relationships of social class to breeding practices, of middle managers to biological information processing, and of transportation to experiences of space and time, that we can begin to locate the conditions that made genetic thinking possible, desirable, and seemingly natural. In describing this historical moment, The Emergence of Genetic Rationality is panoramic in scope, addressing primary texts that range from horse breeding manuals to eugenics treatises, natural history tables to railway surveys, and novels to personal diaries. It draws on the work of figures as diverse as Thorstein Veblen, Jack London, Edith Wharton, William James, and Luther Burbank. The central figure, David Starr Jordan - naturalist, poet, eugenicist, educator - provides the book with a touchstone for deciphering the mode of rationality that genetics superseded. Building on continental philosophy, media studies, systems theory, and theories of narrative, The Emergence of Genetic Rationality provides an inter-disciplinary contribution to intellectual and scientific history, science studies, and cultural studies. It offers a truly encyclopedic cultural history that challenges our own ways of organizing knowledge even as it explicates those of an earlier era. In a time in which genetic rationality has become our own common sense, this discussion of its emergence reminds us of the interdependence of the tools we use to process information and the conceptions of life they animate.

HISTORY AND PHILOSOPHY OF SCIENCE AND TECHNOLOGY -Volume II

Author : Pablo Lorenzano, Hans-Jörg Rheinberger, Eduardo Ortiz and Carlos Delfino Galles
Publisher : EOLSS Publications
Page : 416 pages
File Size : 41,9 Mb
Release : 2010-09-27
Category : Electronic
ISBN : 9781848263246

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HISTORY AND PHILOSOPHY OF SCIENCE AND TECHNOLOGY -Volume II by Pablo Lorenzano, Hans-Jörg Rheinberger, Eduardo Ortiz and Carlos Delfino Galles Pdf

History and Philosophy of Science and Technology is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The Theme on History and Philosophy of Science and Technology in four volumes covers several topics such as: Introduction to the Philosophy of Science; The Nature and Structure of Scientific Theories Natural Science; A Short History of Molecular Biology; The Structure of the Darwinian Argument In The Origin of Species; History of Measurement Theory; Episodes of XX Century Cosmology: A Historical Approach; Philosophy of Economics; Social Sciences: Historical And Philosophical Overview of Methods And Goals; Introduction to Ethics of Science and Technology; The Ethics of Science and Technology; The Control of Nature and the Origins of The Dichotomy Between Fact And Value; Science and Empires: The Geo-Epistemic Location of Knowledge; Science and Religion; Scientific Knowledge and Religious Knowledge - Significant Epistemological Reference Points; Thing Called Philosophy of Technology; Transitions from Function-Oriented To Effect-Oriented Technologies. Some Thought on the Nature of Modern Technology; Technical Agency and Sources of Technological Pessimism These four volumes are aimed at a broad spectrum of audiences: University and College Students, Educators and Research Personnel