Everything About Von Willebrand Disease

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Von Willebrand Disease

Augusto B. Federici,Christine A. Lee,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery
Von Willebrand Disease Book PDF

Author : Augusto B. Federici,Christine A. Lee,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery
Publisher : John Wiley & Sons
Page : 569 pages
File Size : 50,5 Mb
Release : 2011-01-31
Category : Medical
ISBN : 9781444329940

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Von Willebrand Disease by Augusto B. Federici,Christine A. Lee,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery Pdf

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

Hemophilia and Von Willebrand Disease

David Green
Hemophilia and Von Willebrand Disease Book PDF

Author : David Green
Publisher : Academic Press
Page : 286 pages
File Size : 52,6 Mb
Release : 2018-06-14
Category : Medical
ISBN : 9780128129555

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Hemophilia and Von Willebrand Disease by David Green Pdf

Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis. Presents one source of information on Hemophilia and Von Willebrand Disease, as well as Factor VIII and Von Willebrand Factor, eliminating the search through hundreds of journal articles Combines the multi-disciplinary research that is generated from Factor VIII/Von Willebrand Factor – hematology, drug discovery, genetics, cell biology, and oncology Delves into unanswered questions and future directions of this important blood-clotting complex

Textbook of Von Willebrand Disease

Augusto B. Federici,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery
Textbook of Von Willebrand Disease Book PDF

Author : Augusto B. Federici,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery
Publisher : John Wiley & Sons
Page : 307 pages
File Size : 43,6 Mb
Release : 2024-06-04
Category : Medical
ISBN : 9781119419488

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Textbook of Von Willebrand Disease by Augusto B. Federici,Erik E. Berntorp,David Lillicrap,Robert R. Montgomery Pdf

TEXTBOOK OF VON WILLEBRAND DISEASE Comprehensive resource summarizing recent research on von Willebrand disease, showing clinicians how to optimize management of patients with this disorder The newly revised and updated second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2nd edition describes the important and complex role of von Willebrand factor (VWF) in hemostasis and thrombosis, covering not only the current understanding of its molecular biology, but also the association between genetic variants of VWF and different von Willebrand disease (VWD) phenotypes. The text also reviews the important area of the obstetric and gynecological manifestations of VWD, as well as how to manage patients with VWD for surgery. Many advances in agents are included in this updated edition, as well as the wide topics such as VWF in Angiogenesis, and VWF/ADAMTS13 as risk factors of thrombosis. Edited by a team of experts in VWD and an international team of contributors, Textbook of von Willebrand Disease covers sample topics such as: VWF structure and function, biosynthesis and organization of VWF, modulation of VWF by ADAMTS13 and assessment of VWF clearance Clinical, laboratory and molecular markers of different VWD types, from the mild forms of type 1 VWD and the moderate variants types 2A, 2B, 2M, 2N to the most severe type 3 VWD Pediatric aspects of VWD and of women with VWD Management of GI bleeds and appropriate therapies in surgery, and plasma-derived and recombinant VWF concentrates Acquired von Willebrand Syndrome, cardiovascular causes of AVWS, gastrointestinal bleeds in VWD and AVWS, and prophylaxis in von Willebrand disease Providing complete and accessible coverage of the subject, Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2nd edition is a valuable resource for hematologists in practice and in training, along with specialists in thrombosis, hemostasis, and bleeding/clotting disorders.

Congenital Bleeding Disorders

Akbar Dorgalaleh
Congenital Bleeding Disorders Book PDF

Author : Akbar Dorgalaleh
Publisher : Springer
Page : 396 pages
File Size : 44,9 Mb
Release : 2018-07-25
Category : Medical
ISBN : 9783319767239

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Congenital Bleeding Disorders by Akbar Dorgalaleh Pdf

This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.

Pediatric Bleeding Disorders

Amy L. Dunn,Bryce A. Kerlin,Sarah H. O'Brien,Melissa J. Rose,Riten Kumar
Pediatric Bleeding Disorders Book PDF

Author : Amy L. Dunn,Bryce A. Kerlin,Sarah H. O'Brien,Melissa J. Rose,Riten Kumar
Publisher : Springer Nature
Page : 223 pages
File Size : 42,8 Mb
Release : 2020-03-28
Category : Medical
ISBN : 9783030316617

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Pediatric Bleeding Disorders by Amy L. Dunn,Bryce A. Kerlin,Sarah H. O'Brien,Melissa J. Rose,Riten Kumar Pdf

This clinical casebook provides a concise, state-of-the-art review of pediatric bleeding disorders. Presented in a case-based format, each case presents a different variant of bleeding disorder, illustrates the etiology, pathology, genetics, diagnosis, and management of the disorder, and offers clinical pearls. Disorders covered include hemophilia A and B, rare factor deficiencies, von Willebrand disease, immune thrombocytopenia purpura, and platelet dysfunctions. Written by experts in the field, Pediatric Bleeding Disorders: A Clinical Casebook is a valuable resource for clinicians and practitioners treating patients with challenging coagulation issues.

100 Questions and Answers about Von Willebrand Disease

Andra H. James
100 Questions and Answers about Von Willebrand Disease Book PDF

Author : Andra H. James
Publisher : Jones & Bartlett Learning
Page : 148 pages
File Size : 43,8 Mb
Release : 2008-05-07
Category : Medical
ISBN : 0763757675

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100 Questions and Answers about Von Willebrand Disease by Andra H. James Pdf

Preview this title's catalog page in a new window 100 Questions & Answers About Von Willerbrand Disease First Edition Second Edition Third Edition Fourth Edition Fifth Edition Sixth Edition Seventh Edition Eighth Edition Ninth Edition Tenth Edition Eleventh Edition Twelve Edition Authors: Andra H. James, MD, Duke University Medical Center Show degrees: Yes No Show affiliations: Yes No ISBN: 0763757675 ISBN-13: 9780763757670 Price: $17.95 Binding: Paperback Pages: 114 Link for Request Review Copy: http: //www.jbpub.com/cart/compcart.cfm?bc=5767-0&t= Will Publish: 05/21/2008 Copyright: Title Page Text [Edit] EMPOWER YOURSELF! The only text to provide both the patient's and doctor's views, 100 Questions & Answers About Von Willebrand Disease provides a much needed primer for patients and their families. This book address the questions most relevant to those recently diagnosed with the disease, offering up-to-date, authoritative, practical, yet easy to understand answers to your questions about Von Willebrand Disease, including indispensable information about diagnosis and treatment. VWD is a common bleeding disorder, affecting 1% of all people; this valuable resource will help those diagnosed better understand and cope with the disorder.

Bleeding Disorders

David Green,Christopher A. Ludlam
Bleeding Disorders Book PDF

Author : David Green,Christopher A. Ludlam
Publisher : Health Press (UK)
Page : 148 pages
File Size : 49,7 Mb
Release : 2004
Category : Medical
ISBN : NWU:35558005018466

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Bleeding Disorders by David Green,Christopher A. Ludlam Pdf

Fast Facts: Bleeding Disorders keeps a complex subject simple and clinically oriented. The authors have made numerous updates to this second edition to ensure it provides essential information in a readily accessible format.

Consultative Hemostasis and Thrombosis E-Book

Craig S. Kitchens,Barbara A Konkle,Craig M. Kessler
Consultative Hemostasis and Thrombosis E Book Book PDF

Author : Craig S. Kitchens,Barbara A Konkle,Craig M. Kessler
Publisher : Elsevier Health Sciences
Page : 843 pages
File Size : 40,5 Mb
Release : 2013-02-20
Category : Medical
ISBN : 9781455733293

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Consultative Hemostasis and Thrombosis E-Book by Craig S. Kitchens,Barbara A Konkle,Craig M. Kessler Pdf

A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

Live Younger Longer

Stephen Kopecky
Live Younger Longer Book PDF

Author : Stephen Kopecky
Publisher : Simon and Schuster
Page : 306 pages
File Size : 50,9 Mb
Release : 2022-02-16
Category : Health & Fitness
ISBN : 9781945564376

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Live Younger Longer by Stephen Kopecky Pdf

Most of us want to live a long, healthy life, but how do we do that? Drawing upon lessons from his own life, Mayo Clinic cardiologist Stephen Kopecky offers a holistic, evidence-based approach to preventing common diseases and chronic illnesses and living a longer life of pleasure and purpose. In the past century, the leading causes of death around the world have shifted from infectious diseases to long-term chronic illnesses. What’s killing us today isn’t so much flu or tuberculosis, but heart disease and cancer. In fact, more than 1.2 million Americans die from these two diseases each year. Paradoxically, these chronic diseases are a consequence of living longer than ever. But even if we’re living longer, are we living better? The overwhelming number of people now living under the burden of chronic illness indicates otherwise. After surviving two bouts of cancer, Dr. Stephen Kopecky, M.D set out to discover the behaviors people can adopt to live longer lives free of chronic illnesses and diseases. What he discovered was that the answer lies in just six habits that require small changes to your daily life, but reap big results long-term. From adopting better diet and exercise habits to managing stress and sleep, these behaviors will not only preserve your health, they can improve your quality of living and extend your life. The secret, however, lies not just in the steps themselves but in how you accomplish them. This book offers in-depth insights on: The best foods to eat and why Increasing physical activity and improving fitness Why your sleep habits matter The dangers of stress and what to do about them The true impact of alcohol and tobacco on our bodies How to make changes that will last a lifetime After 30 years of research in the field of cardiovascular disease prevention, Dr. Kopecky is sharing what he’s learned from his practice and own personal experience about staying healthy, preventing chronic illnesses, and living younger longer.

Quick Hits in Obstetric Anesthesia

Roshan Fernando,Pervez Sultan,Sioned Phillips
Quick Hits in Obstetric Anesthesia Book PDF

Author : Roshan Fernando,Pervez Sultan,Sioned Phillips
Publisher : Springer Nature
Page : 500 pages
File Size : 47,5 Mb
Release : 2022-02-07
Category : Medical
ISBN : 9783030724870

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Quick Hits in Obstetric Anesthesia by Roshan Fernando,Pervez Sultan,Sioned Phillips Pdf

This book provides easy to follow guidance on how to manage emergency situations and common problems in obstetric anesthesia. The book provides different anesthetic recipes for obstetric procedures and describes challenges that will be encountered on a day-to-day basis. There are trouble-shooting chapters and ‘what to do lists’ for frequent dilemmas. The book covers obstetric-specific resuscitation and medical emergencies seen on the labor ward. Antenatal and postpartum complications relating to anesthesia are covered as well as issues that may arise during follow up of patients who have had neuraxial anesthesia during delivery. Quick Hits in Obstetric Anesthesia should be used as a cognitive aid for emergency cases and as a decision-making tool for urgent management plans. It is a guide to common problems and provides core knowledge to facilitate anesthesia care on labor wards for all grades of anesthetist.

Endothelial Dysfunction

Helena Lenasi
Endothelial Dysfunction Book PDF

Author : Helena Lenasi
Publisher : BoD – Books on Demand
Page : 432 pages
File Size : 41,7 Mb
Release : 2018-10-24
Category : Medical
ISBN : 9781789842531

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Endothelial Dysfunction by Helena Lenasi Pdf

The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.

A Guide to Living with Von Willebrand Disease

Laureen Kelley,Paul Clement
A Guide to Living with Von Willebrand Disease Book PDF

Author : Laureen Kelley,Paul Clement
Publisher : Unknown
Page : 128 pages
File Size : 44,7 Mb
Release : 2021-08
Category : Electronic
ISBN : 1938851102

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A Guide to Living with Von Willebrand Disease by Laureen Kelley,Paul Clement Pdf

The world's first book on the world's most commonly inherited bleeding disorder. Topics include learning to cope with VWD, inheritance, the medical system, treatment, women's issues, health insurance. Complete resource guide and real-life stories.

Textbook of Hemophilia

Christine A. Lee,Erik E. Berntorp,W. Keith Hoots
Textbook of Hemophilia Book PDF

Author : Christine A. Lee,Erik E. Berntorp,W. Keith Hoots
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 48,7 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405143868

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Textbook of Hemophilia by Christine A. Lee,Erik E. Berntorp,W. Keith Hoots Pdf

The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia

Inhibitors to Coagulation Factors

Louis M. Aledort,Leon W. Hoyer,Jeanne M. Lusher,Howard M. Reisner,Gilbert C. White II
Inhibitors to Coagulation Factors Book PDF

Author : Louis M. Aledort,Leon W. Hoyer,Jeanne M. Lusher,Howard M. Reisner,Gilbert C. White II
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461303312

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Inhibitors to Coagulation Factors by Louis M. Aledort,Leon W. Hoyer,Jeanne M. Lusher,Howard M. Reisner,Gilbert C. White II Pdf

"For the blood is the life . . . . "(Deut. 12 :23) " . . . because the blood, in its value as life, makes atonement" (Lev. 17: 11) HemoPhilia is a rare disease, severe hemophilia rarer still, yet the written history of hemophilia extends back over a millennium and a half. In the ancient Middle East, blood and life were coupled. Blood was the primary substance necessary for life, given to God in sacrifice and forbidden as a food to mortals by Levitical law. Blood was essential for rites of purification and consecration. But the flow of blood during menstruation or parturition rendered a woman unclean. The circumcision of a male child required 33 days of "blood purification" by the mother. ' Circumcision, the visible reminder of the covenant of Abraham lijith Yahweh, was required of newborn Jewish males. It "connote(d) suitability for participation in what God is doing. "2 Hence, free and uncontrolled bleeding of the male child during circumcision, during the ratification of God's covenant, would be noted with awe and concern by those of the Jewish faith. It should not be surprising that the first genetic counseling offered to families with hemophilia is found in the Babylonian Talmud (compilation of Jewish law dated to about the third century AD) and concerns the necessity for circumcision in families with what we would now call hemophilia.

Factor VIII - von Willebrand Factor

M. J. Seghatchian,G. F. Savidge
Factor VIII von Willebrand Factor Book PDF

Author : M. J. Seghatchian,G. F. Savidge
Publisher : CRC Press
Page : 384 pages
File Size : 48,8 Mb
Release : 1989-05-31
Category : Medical
ISBN : 0849368294

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Factor VIII - von Willebrand Factor by M. J. Seghatchian,G. F. Savidge Pdf

Written by established investigators, this comprehensive, two-volume review explains current concepts in both scientific and clinical data related to Factor VIII and to Factor VIII deficiency states. Specific emphasis is placed on the pathophysiological relevance of Factor VIII pertaining to future trends in basic scientific and clinical research. Additionally, new methodological approaches are presented. Researchers in the haematology field will find this publication valuable.