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Author : Anja Kern
Publisher : Peter Lang
Page : 304 pages
File Size : 52,5 Mb
Release : 2008
Category : Benchmarking (Management)
ISBN : 3631577338
Originally presented as the author's thesis--Universiteat Stuttgart, 2006.
Author : Sophia Pandya,Nancy Gallagher
Publisher : Universal-Publishers
Page : 235 pages
File Size : 40,9 Mb
Release : 2012
Category : Religion
ISBN : 9781612335476
This volume of essays on the Gulen, or Hizmet (service) movement, a Turkish, Sufi Muslim, and humanitarian civil society group, looks at the recent activities of its followers to practice their form of Islam and carry out collective interfaith projects at the international level. It adds to the newly burgeoning discourse by focusing on the ways in which participants challenge ideological and sectarian boundaries. Included are essays which discuss how the movement is organized, structured, and institutionalized in many parts of the world, explore Turkey's global influence, evaluate criticisms of the movement, and suggest directions for further research. While most previous scholarly attention has focused on the theological and philosophical ideas of Fethullah Gulen, the movement's inspirational figure, less attention has been paid to the ways in which participants have interpreted and carried out Gulen's messages in the contemporary world.
Author : United States. Congress. House. Committee on Government Operations. Conservation and Natural Resources Subcommittee
Publisher : Unknown
Page : 64 pages
File Size : 47,8 Mb
Release : 1969
Category : Government lending
ISBN : UIUC:30112104082224
Author : Anonim
Publisher : Unknown
Page : 168 pages
File Size : 44,5 Mb
Release : 1974
Category : Food industry and trade
ISBN : UIUC:30112069762075
Author : Uday Kishore,Taruna Madan,Robert B. Sim
Publisher : Springer Nature
Page : 249 pages
File Size : 55,5 Mb
Release : 2021-03-12
Category : Medical
ISBN : 9783030670481
The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. · Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations. · The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. · Altered levels of Collectins have been associated with various autoimmune diseases. This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.
Author : United States. Congress Select Committee on Nutrition and Human Needs
Publisher : Unknown
Page : 190 pages
File Size : 48,6 Mb
Release : 1974
Category : Electronic
ISBN : STANFORD:36105119540859
Author : A. Holt
Publisher : Springer Science & Business Media
Page : 199 pages
File Size : 53,6 Mb
Release : 2012-12-06
Category : Computers
ISBN : 9789401155908
Organized Human Activity and Its Support by Computer proposes an answer to the question: what are computers for? With technical expertise, Anatol Holt analyzes human activity and its relevance to computer use. Holt interleaves a theory about the universal aspect of social life with a vision of how to harness computer power. `This book is a culmination of a life of work that exemplifies two characteristics of the author: intellectual passion, and a concern for what matters to people. In the past thirty years, Holt has been a participant in the computing work at every level, from managing computer systems to developing commercial software to publishing theoretical articles in academic journals. His breadth of knowledge and experience makes possible the interweaving of theory and practice that shapes the fabric of this book. People often make a false opposition between theory and practice. In this case, it is a synergy: practice guides the theory, and the theory is grounded in its application.' Terry Winograd, Stanford University Organized Human Activity and Its Support by Computer will be of interest to those concerned with computers, especially those with and interest in `groupware'. Particular relevance to social scientists, management scientists, students of law, and philosophers are also addressed. Though technical in spirit and method, this book does not expect significant prior computer knowledge of the reader.
Author : James Schwoch
Publisher : University of Illinois Press
Page : 208 pages
File Size : 49,8 Mb
Release : 1990
Category : Business & Economics
ISBN : 0252016904
Author : Hanna Henriksson
Publisher : Linköping University Electronic Press
Page : 68 pages
File Size : 55,8 Mb
Release : 2015-04-27
Category : Physical fitness for children
ISBN : 9789175190938
Childhood obesity according to the World Health Organization is one of the most serious public health challenges of the 21st century. The proportion of childhood obesity is high both globally and in Sweden. This is of great concern since obese children tend to stay obese in adulthood. In order to develop strategies to prevent early childhood obesity more knowledge is needed regarding factors explaining why children become overweight and obese. Preventive strategies require accurate and easy-to-use methods to assess physical activity in response to energy expenditure as well as energy intake in young children, but such methods are largely lacking or have shown limited accuracy. The aims of this thesis were: 1) to describe the longitudinal development of body composition from 1 week to 4.5 years of age; 2) to study relationships between measures of body composition and the physical activity level (PAL) at 1.5 and 3 years of age; 3) to evaluate if heart rate recording and movement registration using Actiheart can capture variations in total energy expenditure (TEE) and activity energy expenditure (AEE) at 1.5 and 3 years; 4) to evaluate the potential of a 7-day activity diary to assess PAL at 1.5 and 3 years of age; 5) to evaluate a new tool (TECH) using mobile phones for assessing energy intake at 3 years of age. Healthy children were investigated at 1 and 12 weeks (n=44), at 1.5 (n=44), 3 (n=33) and 4.5 (n=26) years of age. Body composition was measured using air-displacement plethysmography at 1 and 12 weeks and at 4.5 years of age. At 1.5 and 3 years, body composition, TEE, PAL and AEE were assessed using the doubly labelled water method and indirect calorimetry. Heart rate and movements were recorded using Actiheart (four days) and physical activities were registered using the 7-day diary. Energy intake was assessed using TECH during one complete 24-hour period. Average percentage of total body fat (TBF) and average fat mass index (FMI) were higher (+3 to +81 %), while fat-free mass index (FFMI) was slightly lower (-2 to -9 %), in children in the study from 12 weeks until 4.5 years of age when compared to corresponding reference values. A relationship between TBF% and PAL was found both at 1.5 and 3 years of age. At 3 years, but not at 1.5 years, this could be explained by a relationship between PAL and FFMI. Actiheart recordings explained a significant but small fraction (8%) of the variation in free-living TEE at 1.5 and 3 years, and in AEE (6 %) at 3 years, above that explained by body composition variables. At 1.5 and 3 years of age, PAL estimated by means of the activity diary using metabolic equivalent (MET) values by Ainsworth et al. was not significantly different from reference PAL, but the accuracy for individuals was low. Average energy intake assessed by TECH was not significantly different from TEE. However, the accuracy for individuals was poor. The results of this thesis suggest that 1) The higher body fatness of the children in the study compared to the corresponding reference values may indicate the presence of a secular trend in body composition development characterized by a high body fatness. 2) Body fatness might counteract physical activity at 1.5 years of age when the capacity to perform physical activity is limited, but not at 3 years of age when such a capacity has been developed. 3) Actiheart recordings explained a significant but small fraction of the variation in TEE at 1.5 and 3 years, and in AEE at 3 years of age, above that explained by body composition variables. 4) The activity diary and TECH produced mean values in agreement with reference PAL and TEE, respectively, but the accuracy for individual children was low. In conclusion, the results of this thesis suggest the presence of a secular trend in body composition development in healthy Swedish children, from infancy up to 4.5 years of age, which is characterized by a high body fatness. Methods to assess physical activity and energy intake at 1.5 and 3 years of age provided some promising results on a group level, although further research is needed to increase the accuracy of these methods in individual children.
Author : David Naor
Publisher : Frontiers Media SA
Page : 220 pages
File Size : 50,7 Mb
Release : 2016-07-18
Category : Immunologic diseases. Allergy
ISBN : 9782889199136
The biological outcome of Hyaluronan (also hyaluronic acid, abbreviated HA) interaction with its CD44 or RHAMM receptors recently attracted much attention within the scientific community owing to a Nature article by Tian X et al. (Nature 2013; 499:346-9). The article described a life span exceeding 30 years in naked mole rats, whereas the maximal lifespan of mice, to which the naked mole rat is related, is only 4 years. This observation is accompanied by the finding that the naked mole rat, in contrast to the mouse, does not develop spontaneous tumors during this exceptional longevity. The article provides evidence that interaction of long tissue HA (6000-12,000 kDa) of the naked mole rat with cell surface CD44, in contrast to the interaction of short tissue HA (less than 3000 kDa) with the mouse CD44, makes the difference. More specifically, this communication shows that the interaction of short HA with fibroblasts’ CD44 imposes on them susceptibility for malignant transformation, whereas the corresponding interaction with long HA imposes on the fibroblasts a resistance to malignant transformation. The article does not explain the mechanism that underlines these findings. However, the articles, that will be published in the proposed Research Topic in the Inflammation section of Frontiers in Immunology, can bridge not only this gap, but also may explain why interaction between short HA and cell surface CD44 (or RHAMM, an additional HA receptor) enhances the development of inflammatory and malignant diseases. Furthermore, the articles included in the proposed Frontiers Research Topic will show that cancer cells and inflammatory cells share several properties related to the interaction between short HA and cell surface CD44 and/or RHAMM. These shared properties include: 1. Support of cell migration, which allows tumor metastasis and accumulation of inflammatory cells at the inflammation site; 2. Delivery of intracellular signaling, which leads to cell survival of either cancer cells or inflammatory cells; 3. Delivery of intracellular signaling, which activates cell replication and population expansion of either cancer cells or inflammatory cells; and 4. Binding of growth factors to cell surface CD44 of cancer cells or inflammatory cells (i.e., the growth factors) and their presentation to cells with cognate receptors (endothelial cells, fibroblasts), leading to pro-malignant or pro-inflammatory activities. Going back to the naked mole rat story, we may conclude from the proposed articles of this Frontiers Research Topic that the long HA, which displays anti-malignant effect, interferes with the above described pro-malignant potential of the short HA (perhaps by competing on the same CD44 receptor). Extrapolating this concept to Inflammation, the same mechanism (competition?) may be valid for inflammatory (and autoimmune) activities. If this is the case, long HA may be used for therapy of both malignant and inflammatory diseases. Moreover, targeting the interaction between short HA and CD44 (e.g. by anti-CD44 blocking antibodies) may display also a therapeutic effect on both malignant and inflammatory diseases, an issue that encourages not only fruitful exchange of views, but also practical experimental collaboration.
Author : Anonim
Publisher : DIANE Publishing
Page : 30 pages
File Size : 44,8 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9781428941908
Author : United States. Congress. Senate. Committee on Naval Affairs
Publisher : Unknown
Page : 724 pages
File Size : 47,7 Mb
Release : 1930
Category : Electronic
ISBN : STANFORD:36105111201161
Author : Tatjana Tchumatchenko,Ruben Moreno-Bote
Publisher : Frontiers E-books
Page : 237 pages
File Size : 54,5 Mb
Release : 2014-12-03
Category : Brain function
ISBN : 9782889193578
Correlated activity in populations of neurons has been observed in many brain regions and plays a central role in cortical coding, attention, and network dynamics. Accurately quantifying neuronal correlations presents several difficulties. For example, despite recent advances in multicellular recording techniques, the number of neurons from which spiking activity can be simultaneously recorded remains orders magnitude smaller than the size of local networks. In addition, there is a lack of consensus on the distribution of pairwise spike cross correlations obtained in extracellular multi-unit recordings. These challenges highlight the need for theoretical and computational approaches to understand how correlations emerge and to decipher their functional role in the brain.
Author : Julie Greenberg,Wisconsin. Legislature. Legislative Council
Publisher : Legislative Reference Bureau
Page : 44 pages
File Size : 46,9 Mb
Release : 1978
Category : Recycling (Waste, etc.)
ISBN : WISC:89096586482
Author : Leo Lex
Publisher : DIANE Publishing
Page : 84 pages
File Size : 53,8 Mb
Release : 2011-08
Category : Political Science
ISBN : 9781437983968
This report, which is part of an annual series that began in 1997, reviews the activities of the Congressional Budget Office (CBO) under the UMRA of 1995. It covers public laws enacted and legislation considered by the Congress in calendar year 2010 that would impose federal mandates on state, local, or tribal governments or on the private sector. Contents: A Review of CBO¿s Activities in 2010 Under the UMRA; An Overview of Key Provisions in the UMRA 63; Public Laws That Contain Federal Mandates as Defined in the UMRA, 1996 to 2010; Primary Contributors to CBO¿s Analyses of Mandates. Charts and tables. This is a print on demand edition of an important, hard-to-find publication.