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Biopsy Interpretation of the Liver by Stephen A. Geller,Lydia M. Petrovic Pdf
Biopsy Interpretation of the Liver, Second Edition offers pathologists clear, practical guidelines for recognizing and diagnosing the full spectrum of liver disorders. Coverage begins with the basics—including technical considerations, liver anatomy, and examination methods—and progresses to specific disorders, with particular emphasis on histopathology. This completely updated Second Edition includes new material on transplantation pathology and new chapters on immunopathology and molecular pathology of liver diseases. A companion Website will provide the fully searchable text, over 700 additional full-color images of common and rare entities, and a test bank that is ideal for board exam preparation.
Liver Biopsy Evaluation by Gary C. Kanel,Jacob Korula Pdf
Introducing a highly illustrated microscope-side liver pathology reference. The text lists the presenting symptom and then follows through the process to arrive at a diagnosis. Divided into three sections, this reference provides an introduction to liver biopsy evaluation that includes basic morphologic information. This is a step-by-step guide to evaluation. The second section covers histological features seen under a microscope and lists potential diagnoses. The third section lists all liver diseases and includes the pathologic characteristics and clinical/laboratory features of each.
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Scheuer's Liver Biopsy Interpretation by Jay H. Lefkowitch, MD Pdf
For more than 40 years, Scheuer's Liver Biopsy Interpretation has been the pathologist's go-to resource for help in solving diagnostic problems at the microscope. The 9th Edition brings you fully up to date in the field, with coverage of new diagnostic tools, new information on drug-induced liver injury and cytopathology, and many new high-quality illustrations. Throughout the text, you'll find technical tips, diagnostic clues, and pearls that reflect the extensive experience and insight of the late Dr. Peter Scheuer and internationally renowned author Dr. Jay Lefkowitch, making this new edition your standard bench-side guide to today's liver biopsy diagnosis. Avoid diagnostic errors with the extensive coverage of histological differential diagnoses in each chapter. Minimize reporting errors with practical advice on diagnostic pitfalls and how to avoid them. Clearly see how pathology impacts the diagnosis and management of liver disease thanks to histopathologic and clinical correlations throughout. Find terms and descriptions used frequently in pathology reports in the handy glossary - a useful quick reference for trainee pathologists and clinical hepatologists. Use the extensive online image bank to enhance your presentations and reports. Get up-to-date information on all aspects of liver pathology, including acute and chronic hepatitis, biliary tract diseases, childhood disorders and hepatic neoplasms. Stay current with the latest diagnostic tools: histopathology is correlated with clinically relevant molecular genetics and immunohistochemistry to keep you up to date.
Biopsy Interpretation of the Liver by Michael Torbenson Pdf
This title, part of the Biopsy Interpretation Series edited by Jonathan Epstein, is a practical guide and bench reference for practicing surgical pathologists for the interpretation of liver biopsies. Each chapter follows the series format, which parallels and complements the normal diagnostic process, with key differential diagnostic features of specific tumors detailed within each category. It focuses on the practical, diagnostically useful information that is directly relevant to the practice of surgical pathology.
Practical Interpretation of Liver Biopsy, Volume 1 by Xiuli Liu,Jinping Lai,Nirag Jhala Pdf
This volume brings together concise, essential, and up-to-date information on the most commonly encountered non-neoplastic liver diseases. It will be of use in a busy pathology practice setting for both general pathologists and pathology trainees. The checklists at the end of each chapter provide guidance on initiating the workup, generating the report, and suggesting subsequent studies. In addition, this book will be a good reference for liver pathology for hepatologists, other clinicians, and researchers who study the liver.
Non-Neoplastic Liver Pathology by Raul S. Gonzalez,Kay Washington Pdf
This book provides a quick, pattern-based reference for interpreting histologic changes in non-neoplastic liver. It is designed to guide the reader based on morphologic pattern and basic clinical information. Each chapter covers a broad but identifiable pattern of pathologic liver findings (e.g., “portal inflammation” or “steatosis”) and discusses the major disease entities that manifest as such a pattern. As liver biopsies can be complex and daunting, such an approach should improve the reader’s ability to identify a likely diagnosis or differential and to distinguish among the possible disease entities. Sample reports at the end of each chapter offer guidance on how to sign out cases. Non-Neoplastic Liver Pathology: A Pathologist’s Survival Guide will be of value to practicing pathologists without specialized training in hepatic pathology, pathology residents and fellows trying to learn the basics of non-neoplastic liver pathology, and hepatologists interested in reviewing liver biopsies with pathologists
This book is a complete guide to the evaluation and interpretation of liver biopsy specimens for clinicians, providing the latest techniques and advances in the field. Beginning with an introduction to the structure and function of the ‘normal’ liver, and discussion on situations requiring biopsy, and types of specimen, the following sections describe pathologic variations of liver diseases, ways to identify the changes, and qualitative and quantitative evaluation. The book covers the full spectrum of disorders and diseases that may occur in the liver and includes chapters dedicated to liver transplant pathology, and paediatric liver disease. Current terminologies, grading and staging systems used in liver biopsy, are discussed in detail. High definition slides and images enhance learning, and each chapter concludes with ‘points to remember’ highlighting the key features of the topic. Key Points Complete guide to evaluation and interpretation of liver biopsy specimens Covers the full spectrum of liver disorders and diseases Includes discussion on terminologies, grading, and staging systems Features high definition slides and images, and key learning points
Liver Biopsy Interpretation by Peter Joseph Scheuer,Jay H. Lefkowitch Pdf
Evaluate and interpret the full range of liver biopsy specimens with the fully revised New Edition of this practical resource Two internationally respected experts examine the pathologic changes in primary liver disease as well as systemic diseases affecting the liver. More than 400 illustrations - now in full color - depict the appearance of every condition. Gut called a previous edition "the best and most authoritative manual on the interpretation of liver biopsies...A must for anyone involved in liver biopsy diagnosis."
The Non-Invasive Liver Biopsy by Mikael Forsgren Pdf
The liver is one of the largest organs within the human body and it handles many vital tasks such as nutrient processing, toxin removal, and synthesis of important proteins. The number of people suffering from chronic liver disease is on the rise, likely due to the present ‘western’ lifestyle. As disease develops in the liver there are pathophysiological manifestations within the liver parenchyma that are both common and important to monitor. These manifestations include inflammation, fatty infiltration (steatosis), excessive scar tissue formation (fibrosis and cirrhosis), and iron loading. Importantly, as the disease progresses there is concurrent loss of liver function. Furthermore, postoperative liver function insufficiency is an important concern when planning surgical treatment of the liver, because it is associated with both morbidity and mortality. Liver function can also be hampered due to drug-induced injuries, an important aspect to consider in drug-development. Currently, an invasive liver needle biopsy is required to determine the aetiology and to stage or grade the pathophysiological manifestations. There are important limitations with the biopsy, which include, risk of serious complications, mortality, morbidity, inter- and intra-observer variability, sampling error, and sampling variability. Cleary, it would be beneficial to be able investigate the pathophysiological manifestations accurately, non-invasively, and on regional level. Current available laboratory liver function blood panels are typically insufficient and often only indicate damage at a late stage. Thus, it would be beneficial to have access to biomarkers that are both sensitive and responds to early changes in liver function in both clinical settings and for the pharmaceutical industry and regulatory agencies. The main aim of this thesis was to develop and evaluate methods that can be used for a ‘non-invasive liver biopsy’ using magnetic resonance (MR). We also aimed to develop sensitive methods for measure liver function based on gadoxetate-enhanced MR imaging (MRI). The presented work is primarily based on a prospective study on c. 100 patients suffering from chronic liver disease of varying aetiologies recruited due to elevated liver enzyme levels, without clear signs of decompensated cirrhosis. Our results show that the commonly used liver fat cut-off for diagnosing steatosis should be lowered from 5% to 3% when using MR proton-density fat fraction (PDFF). We also show that MR elastography (MRE) is superior in staging fibrosis. Finally we presented a framework for quantifying liver function based on gadoxetate-enhanced MRI. The method is based on clinical images and a clinical approved contrast agent (gadoxetate). The framework consists of; state-of the-art image reconstruction and correction methods, a mathematical model, and a precise model parametrization method. The model was developed and validated on healthy subjects. Thereafter the model was found applicable on the chronic liver disease cohort as well as validated using gadoxetate levels in biopsy samples and blood samples. The liver function parameters correlated with clinical markers for liver function and liver fibrosis (used as a surrogate marker for liver function). In summary, it should be possible to perform a non-invasive liver biopsy using: MRI-PDFF for liver fat and iron loading, MRE for liver fibrosis and possibly also inflammation, and measure liver function using the presented framework for analysing gadoxetate-enhanced MRI. With the exception of an MREtransducer no additional hardware is required on the MR scanner. The liver function method is likely to be useful both in a clinical setting and in pharmaceutical trials.
Practical Interpretation of Liver Biopsy, Volume 2 by Xiuli Liu,Jinping Lai,Nirag Jhala Pdf
This volume brings together concise, essential, and up-to-date information on the most commonly encountered liver masses and lesions, as well as frequently seen neoplasms. It will be of use in a busy pathology practice setting for both general pathologists and pathology trainees. The checklists at the end of each chapter provide guidance on initiating the workup, generating the report, and suggesting subsequent studies. In addition, this book will be a good reference for liver pathology for hepatologists, other clinicians, and researchers who study the liver.
Percutaneous Image-Guided Biopsy by Kamran Ahrar,Sanjay Gupta Pdf
This book provides a comprehensive source for all aspects of percutaneous image-guided biopsy. A synthesis of rationale, technique and evidence-based medicine, it offers a clear approach to imaging, devices, procedures and patient care. Replete with case studies, radiological images, illustrative diagrams and tables, this valuable reference is an indispensable addition to the bookshelves of all radiologists in training as well as practicing radiologists who would like to expand their biopsy service and refine their skills. The easy to follow format, organization and graphic presentations create a high-yield approach to practical information such as indications, technical considerations, anatomical considerations, outcomes and complications. This timely compendium is a necessity in this rapidly progressing field.
Interventional Radiology Procedures in Biopsy and Drainage by Debra A. Gervais,Tarun Sabharwal Pdf
The Techniques in Interventional Radiology series of handbooks describes in detail the various interventional radiology procedures and therapies that are in current practice. The series comprises four titles, which in turn cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage and ablation. Forthcoming are volumes on pediatric interventional radiology and neurointerventional radiology. Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice. Interventional Radiology Procedures in Biopsy and Drainage presents the full array of operations using these techniques. The book is split into two sections – one dedicated to biopsy procedures and the other to drainage procedures. Dr. Debra Gervais is Director of Pediatric Imaging and Associate Director of Abdominal Imaging and Intervention at Massachusetts General Hospital, Boston, Massachusetts, USA. Dr. Tarun Sabharwal is a Consultant Interventional Radiologist at Guy’s and St Thomas’ Hospital, London, UK.
