Pads 2003

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Protein Deimination in Human Health and Disease

Author : Anthony P. Nicholas,Sanjoy K. Bhattacharya,Paul R. Thompson
Publisher : Springer
Page : 474 pages
File Size : 48,5 Mb
Release : 2017-09-20
Category : Medical
ISBN : 9783319582443

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Protein Deimination in Human Health and Disease by Anthony P. Nicholas,Sanjoy K. Bhattacharya,Paul R. Thompson Pdf

Published in 2014, Protein Deimination in Human Health and Disease was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes, Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases. The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer’s disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain injury, inflammatory bowel disease, lupus, bone disease, heart failure, fronto-temporal dementia, and prostate and colon cancer. It also provides updates on the deimination research covering the three seminal diseases first linked to this process (RA, MS and AD), and details how auto-antibodies against citrullinated proteins contribute to disease. In addition, new hypotheses on the possible pathologic mechanisms of citrullinated myelin basic protein and glial fibrillary acidic protein are also proposed. This second edition also outlines the latest developments in therapeutic strategies, including the use of new PAD antagonists and innovative techniques such as micro-vescicles and stem cells as possible mechanisms to treat these conditions.

Sustainable Agriculture Reviews

Author : Eric Lichtfouse
Publisher : Springer
Page : 328 pages
File Size : 47,9 Mb
Release : 2017-01-17
Category : Technology & Engineering
ISBN : 9783319480060

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Sustainable Agriculture Reviews by Eric Lichtfouse Pdf

This book deals with a rapidly growing field aiming at producing food and energy in a sustainable way for humans and their children. It is a discipline that addresses current issues such as climate change, increasing food and fuel prices, poor-nation starvation, rich-nation obesity, water pollution, soil erosion, fertility loss, pest control, and biodiversity depletion. Novel, environmentally-friendly solutions are proposed based on integrated knowledge from sciences as diverse as agronomy, soil science, molecular biology, chemistry, toxicology, ecology, economy, and social sciences. Indeed, sustainable agriculture decipher mechanisms of processes that occur from the molecular level to the farming system to the global level at time scales ranging from seconds to centuries. For that, scientists use the system approach that involves studying components and interactions of a whole system to classical, narrow science. Instead of solving problems using the classical painkiller approach that treats only negative impacts, sustainable agriculture treats problem sources. Because most actual society issues are now intertwined, global, and fast developing, sustainable agriculture will bring solutions to build a safer world. this book series gathers review articles that analyze current agricultural issues and knowledge, then proposes alternative solutions. It will therefore help all scientists, decision makers, professors, farmers and politicians who wish to build a safe agriculture, energy and food system for future generations.

Consumer China

Author : Anonim
Publisher : Unknown
Page : 540 pages
File Size : 45,6 Mb
Release : 2005
Category : Consumers
ISBN : UCSD:31822034853010

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Consumer China by Anonim Pdf

Fugitive Modelling of Braking Noise

Author : Muhammad Zahir Hassan
Publisher : UTeM Press
Page : 216 pages
File Size : 42,7 Mb
Release : 2017-01-01
Category : Technology & Engineering
ISBN : 9789670257891

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Fugitive Modelling of Braking Noise by Muhammad Zahir Hassan Pdf

ISBN : 978-967-0257-89-1 Author : Muhammad Zahir Hassan This book is intended to be introduces to automotive engineers in general and brake engineers in particular, as a reference material to simulate the fugitive phenomenon of automotive disc brake squeal using the numerical modelling approach and validating the work with the experimental investigation. The automotive disc brake squeal has been a major concern in warranty issues and a challenging noise problem for the automotive player in many years.

Psoriasis

Author : Jose O' Daly
Publisher : BoD – Books on Demand
Page : 229 pages
File Size : 50,6 Mb
Release : 2012-03-16
Category : Medical
ISBN : 9789535102816

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Psoriasis by Jose O' Daly Pdf

The purpose of this book is to present a comprehensive analysis of Psoriasis, a disease that affects approximately 2-3% of humanity in all countries. Psoriasis existence is surveyed since the clay tablets of Assyrians and Babylonians 3.000-5.000 years ago, thru the middle ages, the renaissance, XIX and XX centuries.

Microelectronic Applications of Chemical Mechanical Planarization

Author : Yuzhuo Li
Publisher : John Wiley & Sons
Page : 760 pages
File Size : 44,6 Mb
Release : 2007-12-04
Category : Technology & Engineering
ISBN : 0470180897

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Microelectronic Applications of Chemical Mechanical Planarization by Yuzhuo Li Pdf

An authoritative, systematic, and comprehensive description of current CMP technology Chemical Mechanical Planarization (CMP) provides the greatest degree of planarization of any known technique. The current standard for integrated circuit (IC) planarization, CMP is playing an increasingly important role in other related applications such as microelectromechanical systems (MEMS) and computer hard drive manufacturing. This reference focuses on the chemical aspects of the technology and includes contributions from the foremost experts on specific applications. After a detailed overview of the fundamentals and basic science of CMP, Microelectronic Applications of Chemical Mechanical Planarization: * Provides in-depth coverage of a wide range of state-of-the-art technologies and applications * Presents information on new designs, capabilities, and emerging technologies, including topics like CMP with nanomaterials and 3D chips * Discusses different types of CMP tools, pads for IC CMP, modeling, and the applicability of tribometrology to various aspects of CMP * Covers nanotopography, CMP performance and defect profiles, CMP waste treatment, and the chemistry and colloidal properties of the slurries used in CMP * Provides a perspective on the opportunities and challenges of the next fifteen years Complete with case studies, this is a valuable, hands-on resource for professionals, including process engineers, equipment engineers, formulation chemists, IC manufacturers, and others. With systematic organization and questions at the end of each chapter to facilitate learning, it is an ideal introduction to CMP and an excellent text for students in advanced graduate courses that cover CMP or related semiconductor manufacturing processes.

Lemon-Aid Used Cars and Trucks 2011–2012

Author : Phil Edmonston
Publisher : Dundurn
Page : 633 pages
File Size : 42,9 Mb
Release : 2011-04-25
Category : Transportation
ISBN : 9781554889525

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Lemon-Aid Used Cars and Trucks 2011–2012 by Phil Edmonston Pdf

As Toyota skids into an ocean of problems and uncertainty continues in the U.S. automotive industry, Lemon-Aid Used Cars and Trucks 20112012 shows buyers how to pick the cheapest and most reliable vehicles from the past 30 years. Lemon-Aid guides are unlike any other car and truck books on the market. Phil Edmonston, Canada’s automotive Dr. Phil for 40 years, pulls no punches. Like five books in one, Lemon-Aid Used Cars and Trucks is an expos of car scams and gas consumption lies; a do-it-yourself service manual; an independent guide that covers beaters, lemons, and collectibles; an archive of secret service bulletins granting free repairs; and a legal primer that even lawyers cant beat! Phil delivers the goods on free fixes for Chrysler, Ford, and GM engine, transmission, brake, and paint defects; lets you know about Corvette and Mustang tops that fly off; gives the lowdown on Honda, Hyundai, and Toyota engines and transmissions; and provides the latest information on computer module glitches.

Chemistry and Safety of Acrylamide in Food

Author : Mendel Friedman,Don Mottram
Publisher : Springer Science & Business Media
Page : 492 pages
File Size : 41,8 Mb
Release : 2005-04-22
Category : Technology & Engineering
ISBN : 0387239200

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Chemistry and Safety of Acrylamide in Food by Mendel Friedman,Don Mottram Pdf

Interest in the chemistry, biochemistry, and safety of acrylamide is running high. These proceedings contain presentations by experts from eight countries on the chemistry, analysis, metabolism, pharmacology, and toxicology of the compound.

New Research on Acoustics

Author : Benjamin N. Weiss
Publisher : Nova Publishers
Page : 390 pages
File Size : 50,7 Mb
Release : 2008
Category : Medical
ISBN : 1604564032

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New Research on Acoustics by Benjamin N. Weiss Pdf

Acoustics is the science concerned with the production, control, transmission, reception, and effects of sound. Its origins began with the study of mechanical vibrations and the radiation of these vibrations through mechanical waves, and still continue today. Research was done to look into the many aspects of the fundamental physical processes involved in waves and sound and into possible applications of these processes in modern life. The study of sound waves also leads to physical principles that can be applied to the study of all waves. The broad scope of acoustics as an area of interest and endeavour can be ascribed to a variety of reasons. First, there is the ubiquitous nature of mechanical radiation, generated by natural causes and by human activity. Then, there is the existence of the sensation of hearing, of the human vocal ability, of communication via sound, along with the variety of psychological influences sound has on those who hear it. Such areas as speech, music, sound recording and reproduction.

SDI

Author : Anonim
Publisher : Unknown
Page : 292 pages
File Size : 42,5 Mb
Release : 1988
Category : History
ISBN : UCR:31210012327480

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SDI by Anonim Pdf

Strategic Defense Initiative examines developments in the technologies currently being researched under SDI. The OTA does not repeat the work of its earlier reports but gives special attention to filling in gaps in those reports and to describing technical progress made in the intervening period. The report also presents information on the prospects for functional survival against preemptive attack of alternative ballistic missile defense system architectures now being considered under the SDI. Finally, it analyzes the feasibility of developing reliable software to perform the battle management tasks required by such system architectures.

Energy and Water Development Appropriations for 2005

Author : United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Publisher : Unknown
Page : 1008 pages
File Size : 42,8 Mb
Release : 2004
Category : Energy development
ISBN : MINN:31951D024616155

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Energy and Water Development Appropriations for 2005 by United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development Pdf

Copper Wire Bonding

Author : Preeti S Chauhan,Anupam Choubey,ZhaoWei Zhong,Michael G Pecht
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 53,6 Mb
Release : 2013-09-20
Category : Technology & Engineering
ISBN : 9781461457619

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Copper Wire Bonding by Preeti S Chauhan,Anupam Choubey,ZhaoWei Zhong,Michael G Pecht Pdf

This critical volume provides an in-depth presentation of copper wire bonding technologies, processes and equipment, along with the economic benefits and risks. Due to the increasing cost of materials used to make electronic components, the electronics industry has been rapidly moving from high cost gold to significantly lower cost copper as a wire bonding material. However, copper wire bonding has several process and reliability concerns due to its material properties. Copper Wire Bonding book lays out the challenges involved in replacing gold with copper as a wire bond material, and includes the bonding process changes—bond force, electric flame off, current and ultrasonic energy optimization, and bonding tools and equipment changes for first and second bond formation. In addition, the bond–pad metallurgies and the use of bare and palladium-coated copper wires on aluminum are presented, and gold, nickel and palladium surface finishes are discussed. The book also discusses best practices and recommendations on the bond process, bond–pad metallurgies, and appropriate reliability tests for copper wire-bonded electronic components. In summary, this book: Introduces copper wire bonding technologies Presents copper wire bonding processes Discusses copper wire bonding metallurgies Covers recent advancements in copper wire bonding including the bonding process, equipment changes, bond–pad materials and surface finishes Covers the reliability tests and concerns Covers the current implementation of copper wire bonding in the electronics industry Features 120 figures and tables Copper Wire Bonding is an essential reference for industry professionals seeking detailed information on all facets of copper wire bonding technology.