So Simple A Beginning

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So Simple a Beginning

Author : Raghuveer Parthasarathy
Publisher : Princeton University Press
Page : 336 pages
File Size : 44,7 Mb
Release : 2022-02-08
Category : Science
ISBN : 9780691200408

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So Simple a Beginning by Raghuveer Parthasarathy Pdf

A biophysicist reveals the hidden unity behind nature’s breathtaking complexity The form and function of a sprinting cheetah are quite unlike those of a rooted tree. A human being is very different from a bacterium or a zebra. The living world is a realm of dazzling variety, yet a shared set of physical principles shapes the forms and behaviors of every creature in it. So Simple a Beginning shows how the emerging new science of biophysics is transforming our understanding of life on Earth and enabling potentially lifesaving but controversial technologies such as gene editing, artificial organ growth, and ecosystem engineering. Raghuveer Parthasarathy explains how four basic principles—self-assembly, regulatory circuits, predictable randomness, and scaling—shape the machinery of life on scales ranging from microscopic molecules to gigantic elephants. He describes how biophysics is helping to unlock the secrets of a host of natural phenomena, such as how your limbs know to form at the proper places, and why humans need lungs but ants do not. Parthasarathy explores how the cutting-edge biotechnologies of tomorrow could enable us to alter living things in ways both subtle and profound. Featuring dozens of original watercolors and drawings by the author, this sweeping tour of biophysics offers astonishing new perspectives on how the wonders of life can arise from so simple a beginning.

From So Simple a Beginning

Author : Charles Darwin
Publisher : National Geographic Books
Page : 0 pages
File Size : 41,9 Mb
Release : 2010-08-31
Category : Science
ISBN : 9780393061345

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From So Simple a Beginning by Charles Darwin Pdf

Hailed as "superior" by Nature, this landmark volume is available in a collectible, boxed edition. Never before have the four great works of Charles Darwin—Voyage of the H.M.S. Beagle (1845), The Origin of Species (1859), The Descent of Man (1871), and The Expression of Emotions in Man and Animals (1872)—been collected under one cover. Undertaking this challenging endeavor 123 years after Darwin's death, two-time Pulitzer Prize winner Edward O. Wilson has written an introductory essay for the occasion, while providing new, insightful introductions to each of the four volumes and an afterword that examines the fate of evolutionary theory in an era of religious resistance. In addition, Wilson has crafted a creative new index to accompany these four texts, which links the nineteenth-century, Darwinian evolutionary concepts to contemporary biological thought. Beautifully slipcased, and including restored versions of the original illustrations, From So Simple a Beginning turns our attention to the astounding power of the natural creative process and the magnificence of its products.

Start with Why

Author : Simon Sinek
Publisher : Penguin
Page : 258 pages
File Size : 41,9 Mb
Release : 2009-10-29
Category : Business & Economics
ISBN : 9781101149034

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Start with Why by Simon Sinek Pdf

The inspiring, life-changing bestseller by the author of LEADERS EAT LAST and TOGETHER IS BETTER. In 2009, Simon Sinek started a movement to help people become more inspired at work, and in turn inspire their colleagues and customers. Since then, millions have been touched by the power of his ideas, including more than 28 million who’ve watched his TED Talk based on START WITH WHY -- the third most popular TED video of all time. Sinek starts with a fundamental question: Why are some people and organizations more innovative, more influential, and more profitable than others? Why do some command greater loyalty from customers and employees alike? Even among the successful, why are so few able to repeat their success over and over? People like Martin Luther King Jr., Steve Jobs, and the Wright Brothers had little in common, but they all started with WHY. They realized that people won't truly buy into a product, service, movement, or idea until they understand the WHY behind it. START WITH WHY shows that the leaders who've had the greatest influence in the world all think, act, and communicate the same way -- and it's the opposite of what everyone else does. Sinek calls this powerful idea The Golden Circle, and it provides a framework upon which organizations can be built, movements can be led, and people can be inspired. And it all starts with WHY.

No Longer Simple

Author : Melissa Gregory
Publisher : Strategic Book Publishing
Page : 245 pages
File Size : 55,7 Mb
Release : 2012-04-01
Category : Fiction
ISBN : 9781618974129

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No Longer Simple by Melissa Gregory Pdf

For Madison, who has suffered a terrible loss, life is No Longer Simple. The teenager and her family move from Michigan to West Virginia to get over the loss, but she is just starting her senior year in high school, which makes the change especially hard. Making new friends is easy compared to what is coming her way. Madison must juggle school, cheerleading, love, secrets, deception, as well as someone from her past showing up with unforeseen intentions. Maddy wants so badly to go back to having an ordinary life, but you can't always have what you wish for. The teen's life is about to get a lot more complicated in the stunning new novel No Longer Simple: The New Beginning and The Complication.

So Simple Knits

Author : Hilary Mackin
Publisher : Creative Homeowner Press
Page : 128 pages
File Size : 46,7 Mb
Release : 2005-10-15
Category : Crafts & Hobbies
ISBN : 1580112587

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So Simple Knits by Hilary Mackin Pdf

A collection of projects for knitted separates offers step-by-step instructions for such items as sweaters, capes, headbands, coats, and jackets.

Biophysics

Author : William Bialek
Publisher : Princeton University Press
Page : 640 pages
File Size : 49,9 Mb
Release : 2012-12-17
Category : Science
ISBN : 9781400845576

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Biophysics by William Bialek Pdf

Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology--from the discovery of DNA's structure to imaging of the human brain--have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles--the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes Instructor's manual (available only to teachers)

A Not-So-Simple Life

Author : Melody Carlson
Publisher : Multnomah
Page : 258 pages
File Size : 46,5 Mb
Release : 2010-06-02
Category : Young Adult Fiction
ISBN : 9780307498984

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A Not-So-Simple Life by Melody Carlson Pdf

Fifteen-year-old Maya Stark seems to have it all–fame, fortune, a Beverly Hills lifestyle, and an eighties pop star dad who’s making a comeback. But looks can be deceiving, and on the inside, Maya is miserable. Her parents are divorced, her dad is away on tour, and being biracial, she struggles with her identity. Then, to make matters worse, her mother has returned to using drugs and is quickly depleting their finances. In a plan to become emancipated from her messed-up mom, Maya takes a job on Rodeo Drive. Selling designer clothes compromises Maya’s earth-friendly “green girl” values, but she is desperate. Just when Maya thinks she’s got it all worked out, her life caves in. Her mom “embezzles” Maya’s savings and is later arrested on DUI and cocaine possession charges and is facing jail time. With nowhere to live, Maya is sent to spend the summer with her relatives. In the collision of two very different worlds, Maya must figure out where she fits in–or does she fit in at all?

Atomic Habits

Author : James Clear
Publisher : Penguin
Page : 322 pages
File Size : 51,5 Mb
Release : 2018-10-16
Category : Business & Economics
ISBN : 9780735211308

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Atomic Habits by James Clear Pdf

The #1 New York Times bestseller. Over 10 million copies sold! Tiny Changes, Remarkable Results No matter your goals, Atomic Habits offers a proven framework for improving--every day. James Clear, one of the world's leading experts on habit formation, reveals practical strategies that will teach you exactly how to form good habits, break bad ones, and master the tiny behaviors that lead to remarkable results. If you're having trouble changing your habits, the problem isn't you. The problem is your system. Bad habits repeat themselves again and again not because you don't want to change, but because you have the wrong system for change. You do not rise to the level of your goals. You fall to the level of your systems. Here, you'll get a proven system that can take you to new heights. Clear is known for his ability to distill complex topics into simple behaviors that can be easily applied to daily life and work. Here, he draws on the most proven ideas from biology, psychology, and neuroscience to create an easy-to-understand guide for making good habits inevitable and bad habits impossible. Along the way, readers will be inspired and entertained with true stories from Olympic gold medalists, award-winning artists, business leaders, life-saving physicians, and star comedians who have used the science of small habits to master their craft and vault to the top of their field. Learn how to: make time for new habits (even when life gets crazy); overcome a lack of motivation and willpower; design your environment to make success easier; get back on track when you fall off course; ...and much more. Atomic Habits will reshape the way you think about progress and success, and give you the tools and strategies you need to transform your habits--whether you are a team looking to win a championship, an organization hoping to redefine an industry, or simply an individual who wishes to quit smoking, lose weight, reduce stress, or achieve any other goal.

The Molecular Switch

Author : Rob Phillips
Publisher : Princeton University Press
Page : 436 pages
File Size : 48,6 Mb
Release : 2020-09
Category : Science
ISBN : 9780691200248

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The Molecular Switch by Rob Phillips Pdf

A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons. Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.

Recorder from the Beginning: Pupil's Book 1

Author : John Pitts
Publisher : EJA Publications
Page : 48 pages
File Size : 46,9 Mb
Release : 2012-09-19
Category : Music
ISBN : 9780857129383

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Recorder from the Beginning: Pupil's Book 1 by John Pitts Pdf

Recorder From The Beginning: Pupil's Book 1 (2004 Edition) is the full-colour revised edition of John Pitts' best-selling recorder course. The eight extra pages in Book 1 have allowed for some new tunes and rounds, whilst retaining the well-known favourites that have helped to make the scheme such an enduring success. This is the book we all learned from as children and is still, successfully, teaching today's youth how to play the Recorder.

Elm in Action

Author : Richard Feldman
Publisher : Simon and Schuster
Page : 344 pages
File Size : 53,9 Mb
Release : 2020-04-04
Category : Computers
ISBN : 9781638355885

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Elm in Action by Richard Feldman Pdf

Summary Elm is more than just a cutting-edge programming language, it’s a chance to upgrade the way you think about building web applications. Once you get comfortable with Elm’s refreshingly different approach to application development, you’ll be working with a clean syntax, dependable libraries, and a delightful compiler that essentially eliminates runtime exceptions. Elm compiles to JavaScript, so your code runs in any browser, and Elm’s best-in-class rendering speed will knock your socks off. Let’s get started! Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the technology Simply put, the Elm programming language transforms the way you think about frontend web development. Elm’s legendary compiler is an incredible assistant, giving you the precise and user-friendly support you need to work efficiently. Elm applications have small bundle sizes that run faster than JavaScript frameworks and are famously easy to maintain as they grow. The catch? Elm isn’t JavaScript, so you’ll have some new skills to learn. About the book Elm in Action teaches you the Elm language along with a new approach to coding frontend applications. Chapter by chapter, you’ll create a full-featured photo-browsing app, learning as you go about Elm’s modular architecture, Elm testing, and how to work seamlessly with your favorite JavaScript libraries. You’ll especially appreciate author and Elm core team member Richard Feldman’s unique insights, based on his thousands of hours writing production code in Elm. When you’re done, you’ll have a toolbox of new development skills and a stunning web app for your portfolio. What's inside Scalable design for production web applications Single-page applications in Elm Data modeling in Elm Accessing JavaScript from Elm About the reader For web developers with no prior experience in Elm or functional programming. About the author Richard Feldman is a software engineer at NoRedInk and a well-known member of the Elm community. Table of Contents PART 1 - GETTING STARTED 1. Welcome to Elm 2. Your first Elm application 3. Compiler as assistant PART 2 - PRODUCTION-GRADE ELM 4. Talking to servers 5. Talking to JavaScript 6. Testing PART 3 - BUILDING BIGGER 7. Data modeling 8. Single-page applications

Presentation Zen

Author : Garr Reynolds
Publisher : Pearson Education
Page : 316 pages
File Size : 55,7 Mb
Release : 2009-04-15
Category : Business & Economics
ISBN : 9780321601896

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Presentation Zen by Garr Reynolds Pdf

FOREWORD BY GUY KAWASAKI Presentation designer and internationally acclaimed communications expert Garr Reynolds, creator of the most popular Web site on presentation design and delivery on the Net — presentationzen.com — shares his experience in a provocative mix of illumination, inspiration, education, and guidance that will change the way you think about making presentations with PowerPoint or Keynote. Presentation Zen challenges the conventional wisdom of making "slide presentations" in today’s world and encourages you to think differently and more creatively about the preparation, design, and delivery of your presentations. Garr shares lessons and perspectives that draw upon practical advice from the fields of communication and business. Combining solid principles of design with the tenets of Zen simplicity, this book will help you along the path to simpler, more effective presentations.

Cold War

Author : Hourly History
Publisher : Hourly History
Page : 50 pages
File Size : 54,9 Mb
Release : 2016-11-20
Category : History
ISBN : 9781537584829

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Cold War by Hourly History Pdf

The Cold War between the United States and the Soviet Union lasted from the end of World War II until the end of the 1980s. Over the course of five decades, they never came to blows directly. Rather, these two world superpowers competed in other arenas that would touch almost every corner of the globe. Inside you will read about... ✓ What Was the Cold War? ✓ The Origins of the Cold War ✓ World War II and the Beginning of the Cold War ✓ The Cold War in the 1950s ✓ The Cold War in the 1960s ✓ The Cold War in the 1970s ✓ The Cold War in the 1980s and the End of the Cold War Both interfered in the affairs of other countries to win allies for their opposing ideologies. In the process, governments were destabilized, ideas silenced, revolutions broke out, and culture was controlled. This overview of the Cold War provides the story of how these two countries came to oppose one another, and the impact it had on them and others around the world.

Runner's World Complete Book of Beginning Running

Author : Amby Burfoot,Editors of Runner's World Maga
Publisher : Rodale Books
Page : 320 pages
File Size : 54,5 Mb
Release : 2005-02-10
Category : Sports & Recreation
ISBN : 9781605292526

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Runner's World Complete Book of Beginning Running by Amby Burfoot,Editors of Runner's World Maga Pdf

Runner's World Complete Book of Beginning Running by Amby Burfoot is the newest addition to the heralded Runner's World series focuses exclusively on the concerns of the tens of thousands of new runners who take up the sport every year. Recognizing that newcomers to a sport need all the help they can get, Runner's World now devotes an entire book to guiding the beginning runner through those challenging first days, weeks, and months. Peppered throughout with motivating tips and advice from those who have been there, this much-needed volume presents a can't-fail program that is sure to help new runners feel and look better and have more energy and less stress. Inside you'll find: • Information on nutrition and how to adjust your diet to fit your new running lifestyle • Training advice, including how to use cross-training, stretching, and strength exercises to keep enthusiasm up, weight down, and fitness at an optimum level • A special section for women runners Written by the executive editor of Runner's World magazine and covering every problem the new runner may encounter-from choosing the right shoes to preventing injury to preparing for a race-this authoritative volume provides all the information and inspiration any novice requires to turn running into a healthy, lifetime pursuit.

You Are a Beautiful Beginning

Author : Nina Laden
Publisher : Roaring Brook Press
Page : 40 pages
File Size : 52,9 Mb
Release : 2020-08-25
Category : Juvenile Fiction
ISBN : 9781250802507

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You Are a Beautiful Beginning by Nina Laden Pdf

It is not the destination, but the journey. Inspired by this timeless adage, You Are a Beautiful Beginning combines lyrical storytelling and lovely art, blossoming into a celebration of self-love, friendship, and community. With beautiful simplicity and hidden depth, this meditative and magical picture book encourages readers old and young to discover their own endless potential. Kelsey Garrity-Riley's inviting, gently magical art pairs beautifully with a lyrical, deceptively simple text by Nina Laden to create a picture book that is equal parts inspirational story and peaceful lullaby. It is not wishing to be different. It is learning to love being you. It is not the end of your story. It is a beautiful beginning, too. This is another uplifting and original book from bestseller Nina Laden, the creator of Peek-A-Who and the author of If I Had a Little Dream and Yellow Kayak.