Stress And Inflammation In Disorders

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Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics

Jordi Camps
Oxidative Stress and Inflammation in Non communicable Diseases Molecular Mechanisms and Perspectives in Therapeutics Book PDF

Author : Jordi Camps
Publisher : Springer
Page : 223 pages
File Size : 54,8 Mb
Release : 2014-07-19
Category : Medical
ISBN : 9783319073200

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Oxidative Stress and Inflammation in Non-communicable Diseases - Molecular Mechanisms and Perspectives in Therapeutics by Jordi Camps Pdf

Oxidative stress and inflammation underpin most diseases; their mechanisms are inextricably linked. For example, chronic inflammation is associated with oxidation, anti-inflammatory cascades are linked to decreased oxidation, increased oxidative stress triggers inflammation and redox balance inhibits the inflammatory cellular response. Whether or not oxidative stress and inflammation represent the causes or the consequences of cellular pathology, they contribute significantly to the pathogenesis of non-communicable diseases. The incidence of obesity and other related metabolic disturbances are rising, as are age-related diseases due to progressively aging populations. Interrelations between the mechanisms of oxidative stress and of inflammatory signaling and metabolism are, in the broad sense of energy transformation, being increasingly recognized as part of the problem in non-communicable diseases. The book Oxidative Stress and Inflammation in Non-communicable Diseases: Molecular Mechanisms and Perspectives in Therapeutics is an update on the latest research on the molecular basis of non-communicable diseases and the search for possible therapeutic alternatives. The authors of this monograph are experts in their field and the book as a whole, provides an overview of the biochemical alterations underlying diseases such as cardiovascular disease, cancer, obesity, renal disease, neurological diseases and diabetes, emphasizing those aspects that they share in common. We hope that this book will be useful for researchers in biomedicine and also for physicians interested in finding the root causes of the disease, as well as for post-graduate students in biochemistry, molecular biology, nutrition or medicine.

Stress Challenges and Immunity in Space

Alexander Choukèr
Stress Challenges and Immunity in Space Book PDF

Author : Alexander Choukèr
Publisher : Springer
Page : 0 pages
File Size : 54,8 Mb
Release : 2020-12-03
Category : Medical
ISBN : 3030169987

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Stress Challenges and Immunity in Space by Alexander Choukèr Pdf

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

The Psychoneuroimmunology of Chronic Disease

Kathleen A. Kendall-Tackett
The Psychoneuroimmunology of Chronic Disease Book PDF

Author : Kathleen A. Kendall-Tackett
Publisher : American Psychological Association (APA)
Page : 286 pages
File Size : 44,6 Mb
Release : 2010
Category : Medical
ISBN : NWU:35558005756297

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The Psychoneuroimmunology of Chronic Disease by Kathleen A. Kendall-Tackett Pdf

Recent years have witnessed considerable growth in the field of psychoneuroimmunology (PNI), which describes how psychological factors, such as stress and depression, impact the neurological and immune systems. Research increasingly indicates that psychological states play a key role in the development and exacerbation of inflammatory diseases such as heart disease, diabetes, multiple sclerosis, Alzheimers, and autoimmune disorders. In this book, editor Kathleen Kendall-Tackett and an elite group of researchers explore the ways physical and psychological stressors such as poor sleep, PTSD, and depression, trigger the inflammatory response and increase the risk of disease. They approach this material from a variety of perspectives. Chapters in Part I describe the biological processes involved in inflammation, focusing on both the typical bodily response to threat as well as on the long-term deleterious effects of stress upon the immune system; while chapters in Part II examine the role of psychosocial stress in disease etiology. Throughout, chapter authors present evidence of connections between mind and body, and emphasize the need for improved communication between physicians and mental health care providers. This book will be a valuable resource for researchers as well as practitioners who hope to share the benefits of these findings with their clients.

Stress and Inflammation in Disorders

Anonim
Stress and Inflammation in Disorders Book PDF

Author : Anonim
Publisher : Academic Press
Page : 272 pages
File Size : 42,9 Mb
Release : 2017-04-17
Category : Science
ISBN : 9780128123898

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Stress and Inflammation in Disorders by Anonim Pdf

Stress and Inflammation in Disorders, the latest volume in the Advances in Protein Chemistry and Structural Biology series, is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. Provides cutting-edge developments in protein chemistry and structural biology Features new information about protocols and analysis of proteins Contains chapters written by authorities in their respective fields Targeted to a wide audience of researchers, specialists, and students

Inflammation, Lifestyle and Chronic Diseases

Bharat B. Aggarwal,Sunil Krishnan,Sushovan Guha
Inflammation Lifestyle and Chronic Diseases Book PDF

Author : Bharat B. Aggarwal,Sunil Krishnan,Sushovan Guha
Publisher : CRC Press
Page : 504 pages
File Size : 42,7 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439839904

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Inflammation, Lifestyle and Chronic Diseases by Bharat B. Aggarwal,Sunil Krishnan,Sushovan Guha Pdf

Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to chronic diseases through inflammation. While short-term, acute inflammation generated by the immune system serves a therapeutic role, chronic low-level inflammation that may persist "silently" for decades is responsible for chronic diseases. Inflammation, Lifestyle, and Chronic Diseases: The Silent Link describes the role of dysregulated inflammation in persistent and recurring diseases. It investigates links to lifestyle and presents research on how the suppression of proinflammatory pathways may provide opportunities for both prevention and treatment of chronic diseases. The book covers neurodegenerative diseases, pulmonary diseases, asthma, rheumatic and arthritic diseases, skin disease, heart disease, chronic wounds, infectious disease, neuropsychiatric disorders such as depression, gastrointestinal diseases, insulin resistance, and cancer, many of which are also diseases of old age. For each chronic disease, contributors review the clinical and scientific literature and examine current and potential therapies, including conventional pharmacotherapies as well as natural products. Noting that the long-term use of steroids and nonsteroidal anti-inflammatory drugs (NSAIDs) can cause adverse side effects, many of the chapters address the role of dietary agents such as fruits, vegetables, legumes, pulses, nuts, and spices as ideal anti-inflammatory agents that can be consumed regularly. The book also suggests directions for further research. Clinical and science researchers, students, and health professionals interested in the link between inflammation, lifestyle, and chronic diseases will find this an informative resource.

Oxidative Stress, Inflammation, and Health

Young-Joon Surh
Oxidative Stress Inflammation and Health Book PDF

Author : Young-Joon Surh
Publisher : CRC Press
Page : 660 pages
File Size : 42,7 Mb
Release : 2005-05-24
Category : Science
ISBN : 9781420028256

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Oxidative Stress, Inflammation, and Health by Young-Joon Surh Pdf

Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-analyzing the implications of oxidative stress and inflammatory damage in the pathogenesis of human disorders such as cancer, neurodegenerative disease, and diabetes.

Pituitary Adenylate Cyclase-Activating Polypeptide

Hubert Vaudry,Akira Arimura
Pituitary Adenylate Cyclase Activating Polypeptide Book PDF

Author : Hubert Vaudry,Akira Arimura
Publisher : Springer Science & Business Media
Page : 406 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461502432

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Pituitary Adenylate Cyclase-Activating Polypeptide by Hubert Vaudry,Akira Arimura Pdf

Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Sociality, Hierarchy, Health

National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population
Sociality Hierarchy Health Book PDF

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population
Publisher : National Academies Press
Page : 400 pages
File Size : 44,7 Mb
Release : 2014-09-16
Category : Social Science
ISBN : 9780309306645

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Sociality, Hierarchy, Health by National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population Pdf

Sociality, Hierarchy, Health: Comparative Biodemography is a collection of papers that examine cross-species comparisons of social environments with a focus on social behaviors along with social hierarchies and connections, to examine their effects on health, longevity, and life histories. This report covers a broad spectrum of nonhuman animals, exploring a variety of measures of position in social hierarchies and social networks, drawing links among these factors to health outcomes and trajectories, and comparing them to those in humans. Sociality, Hierarchy, Health revisits both the theoretical underpinnings of biodemography and the empirical findings that have emerged over the past two decades.

Inflammation in Psychiatry

A. Halaris,B.E. Leonard
Inflammation in Psychiatry Book PDF

Author : A. Halaris,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Page : 218 pages
File Size : 42,6 Mb
Release : 2013-02-27
Category : Medical
ISBN : 9783318023114

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Inflammation in Psychiatry by A. Halaris,B.E. Leonard Pdf

Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.

Autism

Abha Chauhan,Ved Chauhan,Ted Brown
Autism Book PDF

Author : Abha Chauhan,Ved Chauhan,Ted Brown
Publisher : CRC Press
Page : 452 pages
File Size : 48,9 Mb
Release : 2009-10-26
Category : Medical
ISBN : 1420068873

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Autism by Abha Chauhan,Ved Chauhan,Ted Brown Pdf

In 2007, the Centers for Disease Control and Prevention issued an autism alarm, estimating that one in 150 children may be affected by autism spectrum disorder. Autism has been treated mainly with technical approaches: principally applied behavior analysis and psychopharmacology. The findings in this book implicate oxidative stress as a common feature in autism, and support the claim that oxidative stress and intracellular redox imbalance can be induced or triggered in autism by exposure to certain environmental agents. Such findings could point the way to new treatment approaches in autism. Autism: Oxidative Stress, Inflammation, and Immune Abnormalities brings together a wealth of cutting-edge evidence that is already influencing how we treat this serious condition. It looks at the role of neuropathological abnormalities, genetics, and those factors common to oxidative stress such as inflammation, immune dysfunction, aberrant cellular signaling, and gene-environment interactions. Among dozens of research topics, this volume — Looks at interactions between genetic and environmental factors such as the maternal immune environment and prenatal/postnatal environmental stressors Summarizes evidence for oxidative damage and inflammation in autism Introduces a PDD behavior inventory as a tool for assessing autism Considers autism as an aberrant adaptive response to neuroinflammation and oxidative stress Examines the role of abnormal calcium signaling and the hypothesis that it may represent a target for novel therapeutics Presents a hypothesis that autism arises from the dysregulation of a unified gut/brain system rather than originating in the brain alone Proposes the utility of using a biopsychosocial method to treat autism This book shows us that autism is not only developmental but also a chronic condition based on active pathophysiology, and that it is not only behavioral but also presents somatic and systemic features. The findings in these chapters support the theory that oxidative stress plays an important role in autism. They also point to the value of conducting in-depth mechanistic studies as a way to uncover new targets for therapeutic intervention in autism.

Inflammation and Cancer

Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta
Inflammation and Cancer Book PDF

Author : Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta
Publisher : Springer
Page : 489 pages
File Size : 40,8 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9783034808378

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Inflammation and Cancer by Bharat B. Aggarwal,Bokyung Sung,Subash Chandra Gupta Pdf

This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

The Hypothalamus-Pituitary-Adrenal Axis

Anonim
The Hypothalamus Pituitary Adrenal Axis Book PDF

Author : Anonim
Publisher : Elsevier
Page : 416 pages
File Size : 54,8 Mb
Release : 2008-09-12
Category : Medical
ISBN : 0080559360

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The Hypothalamus-Pituitary-Adrenal Axis by Anonim Pdf

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.

Functional Somatic Symptoms in Children and Adolescents

Kasia Kozlowska,Stephen Scher,Helene Helgeland
Functional Somatic Symptoms in Children and Adolescents Book PDF

Author : Kasia Kozlowska,Stephen Scher,Helene Helgeland
Publisher : Springer Nature
Page : 397 pages
File Size : 41,6 Mb
Release : 2020-09-30
Category : Psychology
ISBN : 9783030461843

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Functional Somatic Symptoms in Children and Adolescents by Kasia Kozlowska,Stephen Scher,Helene Helgeland Pdf

This open access book sets out the stress-system model for functional somatic symptoms in children and adolescents. The book begins by exploring the initial encounter between the paediatrician, child, and family, moves through the assessment process, including the formulation and the treatment contract, and then describes the various forms of treatment that are designed to settle the child’s dysregulated stress system. This approach both provides a new understanding of how such symptoms emerge – typically, through a history of recurrent or chronic stress, either physical or psychological – and points the way to effective assessment, management, and treatment that put the child (and family) back on the road to health and well-being.

Oxidative Stress and Biomaterials

Thomas Dziubla,D Allan Butterfield
Oxidative Stress and Biomaterials Book PDF

Author : Thomas Dziubla,D Allan Butterfield
Publisher : Academic Press
Page : 404 pages
File Size : 45,9 Mb
Release : 2016-05-31
Category : Technology & Engineering
ISBN : 9780128032701

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Oxidative Stress and Biomaterials by Thomas Dziubla,D Allan Butterfield Pdf

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility

Inflammation and Oxidative Stress in Neurological Disorders

Akhlaq A. Farooqui
Inflammation and Oxidative Stress in Neurological Disorders Book PDF

Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
Page : 355 pages
File Size : 48,9 Mb
Release : 2014-01-27
Category : Medical
ISBN : 9783319041117

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Inflammation and Oxidative Stress in Neurological Disorders by Akhlaq A. Farooqui Pdf

Unless new discoveries are made in the prevention or treatment of stroke, Alzheimer's Disease and depression, the number of patients with these diseases is sure to increase dramatically by the year 2050. Thus, developing strategies to retard or delay the onset of stroke, AD and depression these neurological disorders is of critical important. The present monograph will provide current and comprehensive information on the relationship between neuroinflammation and oxidative stress in age-related neurological disorders at the molecular level. The information described in this monograph on lifestyle (diet and exercise), genes and age is intended to facilitate and promote new discoveries for the treatment of age-related neurological disorders.