Synthetic Analgesics Diphenylpropylamines By P A J Janssen

Author : Paul A. J. Janssen
Publisher : Elsevier
Page : 192 pages
File Size : 49,8 Mb
Release : 2014-04-24
Category : Medical
ISBN : 9781483152172

Get Book

Synthetic Analgesics by Paul A. J. Janssen Pdf

Synthetic Analgesics, Part I: Diphenylpropylamines deals with the methods of synthesis, the physical and chemical properties, and the ""analgesic"" activity of diphenylpropylamines. Topics covered include the ""analgesic"" activity of methadone, morphine, pethidine, and codeine in animals; diamines and derivatives; R875 and related basic tertiary amides; esters derived from amino acids and secondary and tertiary alcohols; and ketimines, acyl ketimines, and ketones. This book is comprised of 21 chapters and begins with a brief background on the first chemical and pharmacological experiments on diphenylpropylamines, followed by a discussion on ""analgesic"" activity in humans and animals. The ""analgesic"" activity of methadone, morphine, pethidine, and codeine in animals is considered. The following chapters explore a variety of compounds such as 3:3-diphenylpropylamines, tertiary alcohols, secondary alcohols, primary alcohols, nitriles, diamines and derivatives, primary and secondary amides, acids and acid chlorides, and aldehydes. Sulfones, dissociation constants, and configurational studies are also described. This monograph will be a useful resource for researchers and practitioners in the fields of organic chemistry, analytical chemistry, and pharmacology.

Author : Paul A. J. Janssen
Publisher : Unknown
Page : 183 pages
File Size : 45,7 Mb
Release : 1960
Category : Electronic
ISBN : OCLC:633436800

Get Book

Synthetic Analgesics by Paul A. J. Janssen Pdf

Author : Paul Adriaan Jan Janssen
Publisher : Unknown
Page : 200 pages
File Size : 51,7 Mb
Release : 1960
Category : Analgesics
ISBN : UOM:39015000783335

Get Book

Synthetic Analgesics: Diphenylpropylamines by Paul Adriaan Jan Janssen Pdf

Author : Monique C. Braude
Publisher : Unknown
Page : 616 pages
File Size : 55,7 Mb
Release : 1973
Category : Biochemistry
ISBN : UCSD:31822012814240

Get Book

Narcotic Antagonists by Monique C. Braude Pdf

Author : Erminio Costa,Monique C. Braude,Paul Greengard
Publisher : Raven Press (ID)
Page : 622 pages
File Size : 40,6 Mb
Release : 1969
Category : Medical
ISBN : UCSC:32106006380387

Get Book

Advances in Biochemical Psychopharmacology by Erminio Costa,Monique C. Braude,Paul Greengard Pdf

Author : Anonim
Publisher : Unknown
Page : 1598 pages
File Size : 50,6 Mb
Release : 1961
Category : Cosmetics
ISBN : IOWA:31858017714183

Get Book

Journal of the Society of Cosmetic Chemists by Anonim Pdf

Author : Jon Merrills,Jonathan Fisher
Publisher : Academic Press
Page : 570 pages
File Size : 50,6 Mb
Release : 2013-04-19
Category : Medical
ISBN : 9780123946188

Get Book

Pharmacy Law and Practice by Jon Merrills,Jonathan Fisher Pdf

The fifth edition of Pharmacy Law and Practice provides a straightforward and useable guide for students, practitioners, academics and others interested in pharmacy law and practice in the United Kingdom. This multi-dimensional book includes discussions of socio-political influences on legal developments to provide greater insight to the reader. It clearly sets out the background to regulatory issues together with simple and practical statements of what a pharmacist has to do to obey the law. As in previous editions, this book discusses topics thematically rather than by statute. It is a unique and reader-friendly guide that boils down the complex or difficult language of the law, describes the reasons behind it, and illustrates the application to pharmacy practice. Thoroughly updated to reflect regulatory and legal developments in areas including employment law, online transactions and internet pharmacies, non-medical prescribing and more Takes an intuitive, problem-solving approach and discusses topics thematically rather than by statute to show how all of the larger pieces fit together The electronic version of this book contains valuable links to provide readers with the most current information in a rapidly changing subject area

Author : Alberto Frigerio
Publisher : Springer
Page : 658 pages
File Size : 47,9 Mb
Release : 1978-04-01
Category : Science
ISBN : 0306311380

Get Book

Recent Developments in Mass Spectrometry in Biochemistry and Medicine by Alberto Frigerio Pdf

The papers collected in this volume were presented at the 4th International Symposium on Mass Spectrometry in Biochemistry and Medicine held at Riva del Garda, Italy in June 1977. This meeting was organised by the Italian Group for Mass Spectrometry in Biochemistry and Medicine. The group was founded in Milan, Italy, in 1975 by researchers working in different fields (chemistry, pharmacology, medicine, biology). The aim of the symposium was to bring together people working in different branches of mass spectrometry for mutual discussion, exchange of ideas and experience. I wish to thank Mrs. Judy Baggot, Mrs. Donata Castoldi and Miss Vanna Pistotti for their invaluable technical assistance and countless efforts in the preparation of this volume. Alberto Frigerio Milan, January, 1978 v CONTENTS Newer Aspects of the Biotransformation of Carbamazepine: Structural Characterization of Highly Polar Metabolites • • • • 1 W. J. Richter, P. Kriemler and J. W. Faigle Distribution in Brain Areas of Carbamazepine and Carbamazepine-lO,ll-epoxide in 6-Hydroxydopamine Pretreated Rats 15 C. Pantarotto, V. Crunelli, A. Quattrone, P. Negrini, A. Frigerio and R. Samanin Specific Ion Detection of Aryloxy Beta Blocking Drugs for Metabolic Fate Determinations­ Applications to Alprenolol in Rats and Dogs 29 T. Walle and K. Walle The Use of GC-MS in Perinatal Pharmacology: The Metabolism and Pharmacokinetics of Analgesic Drugs in Mothers and Their Babies • • • • • • • • 49 J. Caldwell, L. J. Notarianni and L. A.

Author : JUCKER
Publisher : Birkhäuser
Page : 320 pages
File Size : 55,7 Mb
Release : 2013-10-03
Category : Science
ISBN : 3034871074

Get Book

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques by JUCKER Pdf

Volume 23 includes six contributions as well as the Index for volumes 16-23. The key-word Index, like those of volumes II and IS, provides the reader with a simple cross-reference to all fields of possible interest, making this series of monographs even more useful as an encyclopaedic reference work. The scientific articles treat various topical areas of drug research, reviewing developments and indicating unsolved problems. The editor hopes to have provided the reader with a useful orientation and reference work. Experience over the last few years has shown that a more rapid publica­ tion of the individual volumes better meets the wishes of readers by keeping pace with the speed of modem research. The present volume, as well as its predecessor, has broken the tradition of 500-600-page volumes in the hope of better satisfying the needs of the readers of this series. Finally, thanks are due to all those who have provided helpful criticism of past volumes, thereby providing valuable advice regarding the form of future volumes, and to Dr. A. Niif for his careful revision of the manu­ scripts and correction of the proofs. Thanks are also due to the publish­ ers and printers Birkhiiuser, in particular Messrs. Th. Birkhiiuser and C. Einsele. July 1979 Dr. E. Jucker Sandoz Ltd., Basel Vorwort Der 23. Band umfasst sechs Beitrage nebst dem Index der Bande 16-23.

Author : Ernst Jucker
Publisher : Birkhäuser
Page : 346 pages
File Size : 44,7 Mb
Release : 2011-12-27
Category : Medical
ISBN : 3034898622

Get Book

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques by Ernst Jucker Pdf

Volume 47 of "Progress in Drug Research" contains eight reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with inotropic steroids, with chemokines and their involvement in a wide range of inflam matory diseases, with the subclassification and nomenclature of ul- and Uz-adrenoceptors, with Chinese traditional medicine, with drug targets in the molecular pathogenesis of asthma, with cytokines and their therapeutic application in immunosuppression and immunostimulation, with alter native medicine and with the potential use of calcium blockers in psy chiatry. These reviews and the quotations of original articles provide the reader with valuable information on several new developments in the world-wide search for new and better medicines. In 1959, when the Editor started this series of monographs, it was his intention to help disseminate informa tion on the vast and fast growing domain of drug research. Already at that time,it was not possible to follow the major individual publications in this field, and the reader was thereby provided with a tool to keep abreast of the latest developments and trends. This goal remained unchanged over the last 37 years, and I believe that the reviews in PDR are useful to the non-specialist who can obtain an overview of a particular field of drug research in a relatively short time.

Author : Ruben Vardanyan,Victor Hruby
Publisher : Elsevier
Page : 634 pages
File Size : 55,7 Mb
Release : 2006-03-10
Category : Medical
ISBN : 008046212X

Get Book

Synthesis of Essential Drugs by Ruben Vardanyan,Victor Hruby Pdf

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

Author : KAREN. CARTWRIGHT DUNNELL (ANN.),Ann Cartwright
Publisher : Routledge
Page : 0 pages
File Size : 49,6 Mb
Release : 2024-04
Category : Electronic
ISBN : 1032718447

Get Book

Medicine Takers, Prescribers and Hoarders by KAREN. CARTWRIGHT DUNNELL (ANN.),Ann Cartwright Pdf

In the early 1970s, the consumption of both prescribed and non-prescribed medicines in Britain was increasing. Originally published in 1972, this book takes a look at the medicine takers and the types of medicine they take. It examines the relationship between self-medication and prescription, and describes the frequency and nature of repeat prescribing. The medicines kept in a random sample of households were counted and analysed, and data about the length of time people hoarded medicines is used as a basis for estimating the proportion of prescribed medicines that are wasted. By putting the views and habits of people as patients alongside information from their general practitioners the study illuminates the relationship between patients and doctors. In addition, variations between people in different social classes direct light on the distribution of care and the equity of services at the time.

Author : David A. Williams,William O. Foye,Thomas L. Lemke
Publisher : Lippincott Williams & Wilkins
Page : 1136 pages
File Size : 41,9 Mb
Release : 2002
Category : Medical
ISBN : 9780683307375

Get Book

Foye's Principles of Medicinal Chemistry by David A. Williams,William O. Foye,Thomas L. Lemke Pdf

This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.

Author : A.F. Casy,R.T. Parfitt
Publisher : Springer Science & Business Media
Page : 526 pages
File Size : 44,8 Mb
Release : 2013-06-29
Category : Medical
ISBN : 9781489905857

Get Book

Opioid Analgesics by A.F. Casy,R.T. Parfitt Pdf

The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.

Author : Istituto di ricerche farmacologiche Mario Negri
Publisher : Raven Press (ID)
Page : 808 pages
File Size : 49,7 Mb
Release : 1978
Category : Medical
ISBN : UOM:39015000871494

Get Book

Factors Affecting the Action of Narcotics by Istituto di ricerche farmacologiche Mario Negri Pdf