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Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 40,7 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808
Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 46,5 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author : Rudolf Nieuwenhuys,Hendrik Jan Donkelaar,Charles Nicholson
Publisher : Springer Science & Business Media
Page : 2270 pages
File Size : 40,8 Mb
Release : 1998
Category : Medical
ISBN : 3540560130
This comprehensive reference is clearly destined to become the definitive anatomical basis for all molecular neuroscience research. The three volumes provide a complete overview and comparison of the structural organisation of all vertebrate groups, ranging from amphioxus and lamprey through fishes, amphibians and birds to mammals. This thus allows a systematic treatment of the concepts and methodology found in modern comparative neuroscience. Neuroscientists, comparative morphologists and anatomists will all benefit from: * 1,200 detailed and standardised neuroanatomical drawings * the illustrations were painstakingly hand-drawn by a team of graphic designers, specially commissioned by the authors, over a period of 25 years * functional correlations of vertebrate brains * concepts and methodology of modern comparative neuroscience * five full-colour posters giving an overview of the central nervous system of the vertebrates, ideal for mounting and display This monumental work is, and will remain, unique; the only source of such brilliant illustrations at both the macroscopic and microscopic levels.
Author : Stanley Jacobson,Elliott M. Marcus
Publisher : Springer Science & Business Media
Page : 419 pages
File Size : 55,8 Mb
Release : 2011-12-02
Category : Medical
ISBN : 9781441996534
In this day where research grants are the primary focus, many young investigators are thrown into neurosciences courses without any prior preparation in neuroanatomy. This book is designed to help prepare them by introducing many of the fundamentals of the nervous system. It represents the essentials of an upper level biology course on the central nervous system. It is not designed to be a clinical approach to the nervous system, but rather it approaches the nervous system from a basic science perspective that intertwines both structure and function as an organizing teaching and learning model. Medical and dental examples are included but the main focus is on neuroscience.
Author : Oscar Alzate
Publisher : CRC Press
Page : 356 pages
File Size : 54,7 Mb
Release : 2009-10-26
Category : Medical
ISBN : 9781420076264
In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Author : Hans J. ten Donkelaar,Martin Lammens,Akira Hori
Publisher : Springer Science & Business Media
Page : 544 pages
File Size : 40,9 Mb
Release : 2006-09-07
Category : Medical
ISBN : 9783540346593
Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.
Author : António Salgado
Publisher : Elsevier
Page : 712 pages
File Size : 41,8 Mb
Release : 2020-06-10
Category : Medical
ISBN : 9780128180853
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Author : Rohan Ramakrishna,Rajiv S. Magge,Ali A. Baaj,Jonathan P.S. Knisely
Publisher : Springer Nature
Page : 725 pages
File Size : 40,5 Mb
Release : 2020-05-27
Category : Medical
ISBN : 9783030429584
This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.
Author : Stephen V. Shepherd
Publisher : John Wiley & Sons
Page : 602 pages
File Size : 50,8 Mb
Release : 2017-01-30
Category : Psychology
ISBN : 9781119994695
Comprehensive and authoritative, The Wiley Handbook of Evolutionary Neuroscience unifies the diverse strands of an interdisciplinary field exploring the evolution of brains and cognition. A comprehensive reference that unifies the diverse interests and approaches associated with the neuroscientific study of brain evolution and the emergence of cognition Tackles some of the biggest questions in neuroscience including what brains are for, what factors constrain their biological development, and how they evolve and interact Provides a broad and balanced view of the subject, reviewing both vertebrate and invertebrate anatomy and emphasizing their shared origins and mechanisms Features contributions from highly respected scholars in their fields
Author : Bruno P. Guiard,Giuseppe Di Giovanni
Publisher : Springer
Page : 446 pages
File Size : 43,8 Mb
Release : 2018-02-14
Category : Medical
ISBN : 9783319704746
5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets.
Author : Fabrice Chretien,Kum Thong Wong,Leroy R. Sharer
Publisher : John Wiley & Sons
Page : 850 pages
File Size : 42,9 Mb
Release : 2020-01-08
Category : Medical
ISBN : 9781119467793
Der neue Band aus der Reihe International Society of Neuropathology wurde anlässlich der British Medical Association (BMA) Awards 2019 wärmstens empfohlen. Die Herausgeber sind Experten des Fachgebiets und beschreiben Infektionen des Nervensystems mit ihren klinischen, pathologischen und genetischen Eigenheiten. Auch seltene Erkrankungen werden in übersichtlichen Kapiteln erläutert, zusammen mit Definitionen, mikrobiologischen Eigenschaften, Epidemiologie, klinischen Ausprägungen, Labortests, Pathologie, Genetik und Behandlungsoptionen.
Author : Kewal K. Jain
Publisher : Humana Press
Page : 0 pages
File Size : 47,9 Mb
Release : 2009-12-17
Category : Medical
ISBN : 1607615282
Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.
Author : George Paxinos
Publisher : Academic Press
Page : 1211 pages
File Size : 45,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323139892
The Human Nervous System is a definitive account of human neuroanatomy, with a comprehensive coverage of the brain, spinal cord, and peripheral nervous system. The cytoarchitecture, chemoarchitecture, connectivity, and major functions of neuronal structures are examined by acknowledged authorities in the field, such as: Alheid, Amaral, Armstrong, Beitz, Burke, de Olmos, Difiglia, Garey, Gerrits, Gibbins, Holstege, Kaas, Martin, McKinley, Norgren, Ohye, Paxinos, Pearson, Pioro, Price, Saper, Sasaki, Schoenen, Tadork, Voogd, Webster, Zilles, and their associates. Large, clearly designed 8-1/2" x 11" format 35 information-packed chapters 500 photomicrographs and diagrams 6,200 bibliographic entries Table of contents for every chapter Exceptionally cross-referenced Detailed subject index Substantial original research work Mini atlases of some brain regions
Author : W.J.A.J. Smeets,R. Nieuwenhuys,B.L. Roberts
Publisher : Springer Science & Business Media
Page : 270 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642689239
Although a large body of data about the structure of the central nervous system of cartilaginous fishes has now been accumulated, a systematic survey of the neuromorphology of this, in so many respects, highly interesting group of animals is lacking. The present book is an effort to fill this gap. The information provided is derived partly from the literature and partly from original observations based on our own material. We have attempted to present a complete review of the relevant literature of the last 25 years, but the earlier literature has also been thoroughly scrutinized. Wherever possible we have commented on the functional significance of the various structures. The information available in the literature has been incorporated with our own findings from a detailed study of four species, the sharks Squalus acanthias and Scyliorhinus canicula, the ray Raja clavata and the holocepha Ii an Hydrolagus collei. Although these species do not reflect the total range of cartilaginous fishes they do exemplify the main features of the major groups.
Author : Emmanuelle Waubant,Timothy E. Lotze
Publisher : Springer
Page : 347 pages
File Size : 55,5 Mb
Release : 2017-11-07
Category : Medical
ISBN : 9783319614076
This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
