The Effects Of Surface Modification On The Osseointegration Of Titanium Dental Implants
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Interface Oral Health Science 2016 by Keiichi Sasaki,Osamu Suzuki,Nobuhiro Takahashi Pdf
This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis-Abiosis Intelligent Interface 2016". It aims to create highly functional and autonomic intelligent interface by combining highly functional interface science with the technology of an evaluation and a control at the interface, with the various topics of biomaterials, innovation for oral science and application, regenerative oral science, and medical engineering. Since 2002, the Tohoku University Graduate School of Dentistry has hosted "Interface Oral Health Science" several times as the main theme of dental research in the twenty-first century, and this is the sixth proceedings of the symposiums following the ones in 2005, 2007, 2009, 2011, and 2014.This book benefits not only dental scientists but also other health scientists including medical physicians and pharmacologists, material scientists, engineers, and any scientist who is involved in variety of disciplines. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Bone Response to Dental Implant Materials by Adriano Piattelli Pdf
Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface
Surface Modification of Titanium Dental Implants by Karan Gulati Pdf
This book provides a comprehensive technical and scientific overview of the surface modification of titanium dental implants. Coverage ranges from basic concepts of surface modification to advanced micro- and nano-engineering strategies employed to achieve augmented bioactivity to meet the needs of compromised patient conditions. A special focus of the book is advanced state-of-the-art electrochemically anodized nanostructures fabricated on implants towards enhanced bioactivity and local therapy. Surface Modification of Titanium Dental Implants will keep you current in the domain of titanium dental implants and will provide an improved understanding of their performance and application. The book will benefit engineers, clinicians, and researchers in biomaterials, biomedical engineering, dental and bone implants, nano-engineering, and technology.
Emerging Nanotechnologies in Dentistry by Karthikeyan Subramani,Waqar Ahmed Pdf
New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants). The use of nanostructures that will work in harmony with the body’s own regenerative processes (eg, to restore tooth structure or alveolar bone) are moving into clinical practice. This book brings together an international team of experts from the fields of nanomaterials, biomedical engineering and dentistry, to cover the new materials and techniques with potential for use intra-orally or extra-orally for the restoration, fixation, replacement, or regeneration of hard and soft tissues in and about the oral cavity and craniofacial region. New dental nanotechnologies include the use of advanced inorganic and organic materials, smart and biomimetic materials, tissue engineering and drug delivery strategies. Book prepared by an interdisciplinary and international group of bio-nanomaterial scientists and dental/oral biomedical researchers Comprehensive professional reference for the subject covering materials fabrication and use of materials for all major diagnostic and therapeutic dental applications – repair,restoration, regeneration, implants and prevention Book focuses in depth on the materials manufacturing processes involved with emphasis on pre-clinical and clinical applications, use and biocompatibility
The first section of the book includes the following topics: fusion-based additive manufacturing (AM) processes of titanium alloys and their numerical modelling, mechanism of ?-case formation mechanism during investment casting of titanium, genesis of gas-containing defects in cast titanium products. Second section includes topics on behavior of the (? + ?) titanium alloys under extreme pressure and temperature conditions, hot and super plasticity of titanium (? + ?) alloys and some machinability aspects of titanium alloys in drilling. Finally, the third section includes topics on different surface treatment methods including nanotube-anodic layer formation on two phase titanium alloys in phosphoric acid for biomedical applications, chemico-thermal treatment of titanium alloys applying nitriding process for improving corrosion resistance of titanium alloys.
Effect of Ionic Liquid Coatings on Early Healing and Osseointegration of Titanium Implants by Sutton E. Wheelis Pdf
Although titanium (Ti) dental implants are known to achieve high success rates and osseointegration in vivo, a higher incidence of implant failures have been recently reported. Implant failures are caused by several factors; however, the nature and intensity of the inflammatory response at the titanium-tissue interface determines the healing outcome of an implant. Surface modifications performed on titanium implants have attempted to directly address both patient and external factors that interfere with constructive inflammation, but often do not address multiple complications that impact osseointegration while maintaining regenerative healing. Dicationic imidazolium-based ionic liquids (IonL) have demonstrated low toxicity, antimicrobial, lubricant, and anticorrosive activities in vitro making them a potential candidate as a multifunctional dental implant coatings. However, the biological response to these coatings in vivo is unknown. The goal of this dissertation was to evaluate the effect IonLs have on inflammation, healing, and osseointegration of titanium dental implants. This research is divided into three aims (i) to investigate the biocompatibility of IonL in a subcutaneous model, (ii) to define and validate success criteria for an oral implantation model and (iii) to investigate the impact of IonL on early healing and osseointegration in an oral implantation model. In each aim a combination of clinical evaluation, histopathology, immunohistochemistry, molecular analysis, and MicroCT was used to track inflammation and healing from 2-30 days (d) in the Lewis rat. In aim 1, an initial evaluation of both IonL-Phe and IonL-Met indicated that IonL appeared in peri-implant tissues and increased acute inflammation at 2d compared to uncoated Ti. At 14d, inflammation receded with more developed peri-implant tissue in coated and uncoated samples with no foreign body giant cells. IonL was no longer observed at 14d, suggesting elution or resorption by macrophages. This aim demonstrated that medium dose IonL-Phe does not significantly interfere with Ti foreign body response in an aseptic environment. In aim 2, a new pre-clinical oral implantation model defined an appropriate baseline for successful Ti osseointegration. Healing was similar to other rodent models: hematoma and acute inflammation at 2d, initial bone formation at 7d, advanced bone formation and remodeling at 14d, and bone maturation at 30d. Overall, this model resulted in a 78.5% osseointegration success rate (>60% bone-to-implant contact (BIC)), similar to human osseointegration. Therefore, This model combines the advantages of a rodent model while maximizing BIC, making it an excellent candidate for evaluation of IonLs. Following aim 2, a pilot in vivo assessment determined medium dose IonL-Phe demonstrated the best histogical response and BIC for the remaining evaluation. In aim 3, IonL-Phe-coated and uncoated cpTi screws were implanted into several demographic groups of rats to represent biological variations that could affect healing. Molecular and histological analysis indicated IonL heightened acute inflammation compared to uncoated Ti. However, the coating was released/resorbed by 7 days and did not negatively affect subsequent bone remodeling in all demographics. Overall, IonL-Phe coating did not disturb oral Ti osseointegration and may provide additional control over the healing environment in scenarios known to be challenged by bacteria, such as peri-implantitis
Surface Modification of Titanium for Biomaterial Applications by Kyo-Han Kim,Ramaswamy Narayanan,Tapash R. Rautray Pdf
This book starts with concepts of bone, its structure, remodelling, materials for implants and implant testing methods. Calcium phosphate ceramics and need for titanium surface modification are detailed in the initial chapters. Surface modification techniques include plasma spraying, sol-gel, biomimetic, electrochemical, laser, sputtering and ion-implantation methods. Chapters 5 to 19 deal with these modification techniques. Chapters 20-22 deal with less-common methods titanium nitride coating, protein modification, diamond like carbon coating and ultraviolet treatment. Substituting the apatite lattice with other cations like silicon, magnesium, sodium, carbon, etc is provided. The chapters involving these techniques begin with a small introduction about that technique and go on to explain the underlying principles, methodology and properties of the coats. According to the authors, the book gives a complete overview of almost all the surface modification techniques known, as applied to titanium biomaterials.
Titanium in Medical and Dental Applications by Francis H Froes,Ma Qian Pdf
Titanium in Medical and Dental Applications is an essential reference book for those involved in biomedical materials and advanced metals. Written by well-known experts in the field, it covers a broad array of titanium uses, including implants, instruments, devices, the manufacturing processes used to create them, their properties, corrosion resistance and various fabrication approaches. Biomedical titanium materials are a critically important part of biomaterials, especially in cases where non-metallic biomedical materials are not suited to applications, such as the case of load-bearing implants. The book also covers the use of titanium for implants in the medical and dental fields and reviews the use of titanium for medical instruments and devices. Provides an understanding of the essential and broad applications of Titanium in both the medical and dental industries Discusses the pathways to manufacturing titanium into critical biomedical and dental devices Includes insights into further applications within the industry
Bioactive Materials for Disease Diagnosis and Therapy by Dan Shao,Mingqiang Li,Jie Tang,Yuce Li Pdf
With their advantages of controlled delivery and modular flexibility, biomaterials have fundamentally revolutionized disease diagnosis and therapy. Bioactive nanomaterials are not simple miniaturizations of macroscopic materials. They exhibit unique and intrinsic bioactivities as they readily acquire a precise structure upon interaction with the biological environment. Nowadays, bioactive materials offer great potential in eliciting specific responses and regulations of living tissues for diagnostics, therapeutics, and regenerative medicine. We are optimistic that the increasing innovations and advances in bioactive and biomimetic materials with sophisticated bioactivities and controllable responsiveness will make an important contribution to the next generation of biomaterials and biomedical engineering.
Handbook of Research on Nano-Drug Delivery and Tissue Engineering by Rajakumari Rajendran,Hanna J. Maria,Sabu Thomas,Nandakumar Kalarikkal Pdf
With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.
Metallic Biomaterials Processing and Medical Device Manufacturing by Cuie Wen Pdf
Metallic Biomaterials Processing and Medical Device Manufacturing details the principles and practices of the technologies used in biomaterials processing and medical device manufacturing. The book reviews the main categories of metallic biomaterials and the essential considerations in design and manufacturing of medical devices. It bridges the gap between the designing of biomaterials and manufacturing of medical devices including requirements and standards. Main themes of the book include, manufacturing, coatings and surface modifications of medical devices, metallic biomaterials and their mechanical behaviour, degradation, testing and characterization, and quality controls, standards and FDA regulations of medical devices. The leading experts in the filed discuss the requirements, challenges, recent progresses and future research directions in the processing of materials and manufacturing of medical devices. Metallic Biomaterials Processing and Medical Device Manufacturing is ideal for those working in the disciplines of materials science, manufacturing, biomedical engineering, and mechanical engineering. Reviews key topics of biomaterials processing for medical device applications including metallic biomaterials and their mechanical behavior, degradation, testing and characterization Bridges the gap between biomaterials design and medical device manufacturing Discusses the quality controls, standards, and FDA requirements for biomaterials and medical devices
Misch's Contemporary Implant Dentistry by Randolph Resnik Pdf
Dental implant surgery is an artform. To help you advance your skills and become a master of implant prosthetics, Misch's Contemporary Implant Dentistry, 4th Edition uses a multidisciplinary approach to cover the industry’s most current processes and surgical procedures. The new edition of this text continues to provide comprehensive, state-of-the-art information on the science and discipline of contemporary implant dentistry. Covering the breadth of dental implant surgery, it includes full-color, in-depth coverage of both simple and complicated clinical cases, with practical guidance on how to apply the latest research, diagnostic tools, treatment planning, implant designs, and materials. New author Randolph R. Resnik, is an internationally known educator, clinician, and researcher in the field of Oral Implantology and Prosthodontics who will continue Dr. Misch’s legacy and teachings. Content reflects original author’s philosophy and surgical protocols for dental implants giving you a system for achieving predictable outcomes. Evidence-based approach to dental implant procedures features state-of-the-art guidance supported by the best available research evidence. Rich art program throughout text highlights and clarifies key clinical concepts and techniques with over 2,500 images, radiographs, full-color clinical photographs, line art, and diagrams. Definitive resource in implant dentistry provides you with authoritative state-of-the art guidance by recognized leader in the field. Internationally known author, Randolph R. Resnik, DMD, MDS is a leading educator, clinician, author and researcher in the field of Oral Implantology and Prosthodontics. Surgical protocols provide the latest, most up-to-date literature and techniques that provide a proven system for comprehensive surgical treatment of dental implant patients. Thoroughly revised content includes current diagnostic pharmacologic and medical evaluation recommendations to furnish the reader with the latest literature-based information. Proven strategies and fundamentals for predictable implant outcomes Latest implant surgical techniques for socket grafting and ridge augmentation procedures Proven, evidence-based solutions for the treatment of peri-implant disease Includes the use of dermal fillers and botox in oral implantology Up-to-date information on advances in the field reflects the state-of-the-art dental implantology. Addition of an ExpertConsult site allows you to search the entire book electronically.
Biomaterials for Oral and Dental Tissue Engineering by Lobat Tayebi,Keyvan Moharamzadeh Pdf
Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. Connects materials science with restorative dentistry Focuses on the unique field of intraoral tissues Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues
Cellular Response to Biomaterials by Lucy Di Silvio Pdf
The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants
Author : Georgios E. Romanos Publisher : John Wiley & Sons Page : 256 pages File Size : 44,8 Mb Release : 2021-01-05 Category : Medical ISBN : 9781119583349
Advanced Laser Surgery in Dentistry by Georgios E. Romanos Pdf
Advanced Laser Surgery in Dentistry delivers a state-of-the-art reference for laser technology in the context of a dental practice. The book encompasses oral surgery, periodontology, and implant dentistry, covering the latest research, knowledge, and clinical practices. The author demonstrates the clinical relevance by including many real-world clinical cases that illustrate the application of the discussed techniques. The book includes high-quality, color photographs throughout to support the text and add visual information to the covered topics, which include wound healing, oral surgery, periodontology, implant dentistry, and laser fundamentals and safety considerations. Advanced Laser Surgery in Dentistry provides readers with a step-by-step guide for using lasers in dental practice and discusses likely new directions and possible future treatments in the rapidly advancing field of laser dentistry. Readers will also benefit from a wide variety of subjects, including: A thorough introduction to the fundamentals of lasers, including the beam, the laser cavity, active mediums, lenses, resonators, and delivery systems An exploration of lasers and wound healing, including soft tissue and bone healing, as well as laser-assisted excisions and osteotomies An analysis of lasers in periodontology, including laser-assisted bacteria reduction in the periodontal tissues and the removal of subgingival dental calculus A discussion of lasers in implant dentistry and treatment for peri-implantitis Perfect for oral and maxillofacial surgeons, periodontists, and implant dentists, as well as general dentists, Advanced Laser Surgery in Dentistry will also earn a place in the libraries of dental students and residents seeking to improve their understanding of laser-based oral and dental procedures with a carefully organized reference guide.
