Through The Gate Of Time Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Through The Gate Of Time book. This book definitely worth reading, it is an incredibly well-written.
From the New York Times–bestselling author of the Riverworld series: An alternate history classic in which the American continents never existed. Two Hawks from Earth, an expanded and revised version of Philip José Farmer’s The Gate of Time, is the story of an Iroquois pilot in World War II. First Lt. Roger Two Hawks is on a bombing run over Romania when his aircraft is shot down and collides with a German plane midair. Two Hawks bails out and survives, but when he reaches the ground, gone are the suburbs he saw from the sky. Instead, there are dirt roads, trees, farms, and an unsettling quiet. Then Two Hawks sees the soldiers: fur-clad men with shiny steel helmets shaped like wolf heads and armed with swords and arrows. Soon he comes to understand that, though a world war still rages, the Americans are absent—because they don’t exist, and neither does the land they’d come from. With his modern-day military and technical knowledge, Two Hawks becomes a prize that both armies covet. But he’ll have to learn to play by the rules of a new realm in order to survive—and live to see another world . . . Praise for Philip José Farmer “An excellent science fiction writer.” —Isaac Asimov “[Farmer’s work is a] blend of intellectual daring and pulp fiction prose.” —The New York Times “Farmer offers his audience a wide-screen adventure that never fails to provoke, amuse, and educate. . . . His imagination is certainly of the first rank.” —Time on The World of Tiers
DigiCat Publishing presents to you this special edition of "The Gate of the Year" by Minnie Louise Haskins. DigiCat Publishing considers every written word to be a legacy of humankind. Every DigiCat book has been carefully reproduced for republishing in a new modern format. The books are available in print, as well as ebooks. DigiCat hopes you will treat this work with the acknowledgment and passion it deserves as a classic of world literature.
Author : Thorsten R. Doeppner,Dirk M. Hermann Publisher : Frontiers Media SA Page : 158 pages File Size : 51,5 Mb Release : 2016-01-15 Category : Electronic book ISBN : 9782889197248
Stem Cells and Progenitor Cells in Ischemic Stroke - Fashion or Future? by Thorsten R. Doeppner,Dirk M. Hermann Pdf
Stroke remains one of the most devastating diseases in industrialized countries. Recanalization of the occluded arterial vessel using thrombolysis is the only causal therapy available. However, thrombolysis is limited due to severe side effects and a limited time window. As such, only a minority of patients receives this kind of therapy, showing a need for new and innovative treatment strategies. Although neuroprotective drugs have been shown to be beneficial in a variety of experimental stroke models, they ultimately failed in clinical trials. Consequently, recent scientific focus has been put on modulation of post-ischemic neuroregeneration, either via stimulation of endogenous neurogenesis or via application of exogenous stem cells or progenitor cells. Neurogenesis persists within the adult brain of both rodents and primates. As such, neural progenitor cells (NPCs) are found within distinct niches like the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone of the dentate gyrus. Cerebral ischemia stimulates these astrocyte-like progenitor cells, upon which NPCs proliferate and migrate towards the site of lesion. There, NPCs partly differentiate into mature neurons, without significantly being integrated into the residing neural network. Rather, the majority of new-born cells dies within the first weeks post-stroke, leaving post-ischemic neurogenesis a phenomenon of unknown biological significance. Since NPCs do not replace lost brain tissue, beneficial effects observed in some studies after either stimulated or protected neurogenesis are generally contributed to indirect effects of these new-born cells. The precise identification of appropriated cellular mediators, however, is still elusive. How do these mediators work? Are they soluble factors or maybe even vesicular structures emanating from NPCs? What are the cues that guide NPCs towards the ischemic lesion site? How can post-ischemic neurogenesis be stimulated? How can the poor survival of NPCs be increased? In order to support post-ischemic neurogenesis, a variety of research groups have focused on application of exogenous stem/progenitor cells from various tissue sources. Among these, cultivated NPCs from the SVZ and mesenchymal stem cells (MSCs) from the bone marrow are frequently administered after induction of stroke. Although neuroprotection after delivery of stem/progenitor cells has been shown in various experimental stroke models, transplanted cells are usually not integrated in the neural network. Again, the vast amount of grafted cells dies or does not reach its target despite profound neuroprotection, also suggesting indirect paracrine effects as the cause of neuroprotection. Yet, the factors being responsible for these observations are under debate and still have to be addressed. Is there any “optimal” cell type for transplantation? How can the resistance of grafted cells against a non-favorable extracellular milieu be increased? What are the molecules that are vital for interaction between grafted cells and endogenous NPCs? The present research topic seeks to answer - at least in part - some of the aforementioned questions. Although the research topic predominantly focuses on experimental studies (and reviews alike), a current outlook towards clinical relevance is given as well.
Systems of Insight for Digital Transformation: Using IBM Operational Decision Manager Advanced and Predictive Analytics by Whei-Jen Chen,Rajeev Kamath,Alexander Kelly,Hector H. Diaz Lopez,Matthew Roberts,Yee Pin Yheng,IBM Redbooks Pdf
Systems of record (SORs) are engines that generates value for your business. Systems of engagement (SOE) are always evolving and generating new customer-centric experiences and new opportunities to capitalize on the value in the systems of record. The highest value is gained when systems of record and systems of engagement are brought together to deliver insight. Systems of insight (SOI) monitor and analyze what is going on with various behaviors in the systems of engagement and information being stored or transacted in the systems of record. SOIs seek new opportunities, risks, and operational behavior that needs to be reported or have action taken to optimize business outcomes. Systems of insight are at the core of the Digital Experience, which tries to derive insights from the enormous amount of data generated by automated processes and customer interactions. Systems of Insight can also provide the ability to apply analytics and rules to real-time data as it flows within, throughout, and beyond the enterprise (applications, databases, mobile, social, Internet of Things) to gain the wanted insight. Deriving this insight is a key step toward being able to make the best decisions and take the most appropriate actions. Examples of such actions are to improve the number of satisfied clients, identify clients at risk of leaving and incentivize them to stay loyal, identify patterns of risk or fraudulent behavior and take action to minimize it as early as possible, and detect patterns of behavior in operational systems and transportation that lead to failures, delays, and maintenance and take early action to minimize risks and costs. IBM® Operational Decision Manager is a decision management platform that provides capabilities that support both event-driven insight patterns, and business-rule-driven scenarios. It also can easily be used in combination with other IBM Analytics solutions, as the detailed examples will show. IBM Operational Decision Manager Advanced, along with complementary IBM software offerings that also provide capability for systems of insight, provides a way to deliver the greatest value to your customers and your business. IBM Operational Decision Manager Advanced brings together data from different sources to recognize meaningful trends and patterns. It empowers business users to define, manage, and automate repeatable operational decisions. As a result, organizations can create and shape customer-centric business moments. This IBM Redbooks® publication explains the key concepts of systems of insight and how to implement a system of insight solution with examples. It is intended for IT architects and professionals who are responsible for implementing a systems of insights solution requiring event-based context pattern detection and deterministic decision services to enhance other analytics solution components with IBM Operational Decision Manager Advanced.
Conversation Peace by Mary Kassian,Betty Hassler Pdf
Have you ever left a conversation feeling like shredded wheat? Stuck your foot in your mouth? Been at a loss for words? Had difficulty getting your point across? Or been talked into doing something you didn’t want to do? Do you find it difficult to connect with others? Do you suspect that your speech patterns are hindering your relationships? Maybe you need some Conversation Peace!Let Mary Kassian teach you the seven powerful speech-transforming elements to master the skill of effective communications. You will also strengthen your vocabulary with Words from the Word. Conversation Peace will help you revolutionize your speech habits and improve your relationships.
#1 NEW YORK TIMES BESTSELLER • PULITZER PRIZE FINALIST • This inspiring, exquisitely observed memoir finds hope and beauty in the face of insurmountable odds as an idealistic young neurosurgeon attempts to answer the question What makes a life worth living? NAMED ONE OF PASTE’S BEST MEMOIRS OF THE DECADE • NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • People • NPR • The Washington Post • Slate • Harper’s Bazaar • Time Out New York • Publishers Weekly • BookPage Finalist for the PEN Center USA Literary Award in Creative Nonfiction and the Books for a Better Life Award in Inspirational Memoir At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi’s transformation from a naïve medical student “possessed,” as he wrote, “by the question of what, given that all organisms die, makes a virtuous and meaningful life” into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. “I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything,” he wrote. “Seven words from Samuel Beckett began to repeat in my head: ‘I can’t go on. I’ll go on.’” When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.
Israel and the Covenants in New Testament Times by Peter Williams Pdf
A Bible student reference A New Testament prophecy of a falling away from truth into apostasy and lawlessness, in the final generation before Jesus Christ returns in glory, is being fulfilled now and is shortly to end. Yet Christianity has overwhelmingly moved so far from its first century roots that it could not even recognise this – or that Christ’s return is therefore now almost upon us! How and why this is the case is here explained thoroughly and logically with many examples directly from the word of God. In God’s saving plan for the world, everyone must in time make a free will choice to become part of the ‘Israel of God’ in order to access eternal life in the kingdom of God. The route to take is the “strait and narrow” way (Mat 7:13-14) that very few have so far found, and it involves the biblical new and old covenants which both apply to this Israel. Embark on this voyage only if you are willing to: be challenged about some basic Christian preconceptions, be a serious open-minded Bible student, and trust what the Bible teaches - but remember that time is short. “What the Bible has taught me I see as both vital and urgent for our eternal salvation; yet I know of no church or individual theologian who teaches what this book deals with in any substantive way” “Be prepared for major challenges to your understanding just as God has challenged me.” “In the epistles, Paul refers to two Israels whom he calls Israel after the flesh (I Cor 10:18) and the Israel of God (Gal 6:16); I focus mainly on the latter (but I also explain an unexpected but critically important connection between them)” “Dependent on the teaching, nearly all Christian denominations either teach nothing at all on it or almost the opposite of what Scripture repeatedly showed me. Looking back, I find this absolutely staggering!” “Very few [Christians] understand that the new covenant also only applies to Israel (as I will clearly show).” “I no longer believe that the NT [New Testament] can be fully understood without this extra Israel dimension” “Had I felt I could deliver this in a more light-hearted way I would have done so, but its implications are too awesome and fundamental to our eternal life prospects for that”
Optical Fiber Telecommunications VB by Ivan Kaminow,Tingye Li,Alan E. Willner Pdf
Optical Fiber Telecommunications V (A&B) is the fifth in a series that has chronicled the progress in the research and development of lightwave communications since the early 1970s. Written by active authorities from academia and industry, this edition not only brings a fresh look to many essential topics but also focuses on network management and services. Using high bandwidth in a cost-effective manner for the development of customer applications is a central theme. This book is ideal for R&D engineers and managers, optical systems implementers, university researchers and students, network operators, and the investment community. Volume (A) is devoted to components and subsystems, including: semiconductor lasers, modulators, photodetectors, integrated photonic circuits, photonic crystals, specialty fibers, polarization-mode dispersion, electronic signal processing, MEMS, nonlinear optical signal processing, and quantum information technologies. Volume (B) is devoted to systems and networks, including: advanced modulation formats, coherent systems, time-multiplexed systems, performance monitoring, reconfigurable add-drop multiplexers, Ethernet technologies, broadband access and services, metro networks, long-haul transmission, optical switching, microwave photonics, computer interconnections, and simulation tools. Biographical Sketches Ivan Kaminow retired from Bell Labs in 1996 after a 42-year career. He conducted seminal studies on electrooptic modulators and materials, Raman scattering in ferroelectrics, integrated optics, semiconductor lasers (DBR , ridge-waveguide InGaAsP and multi-frequency), birefringent optical fibers, and WDM networks. Later, he led research on WDM components (EDFAs, AWGs and fiber Fabry-Perot Filters), and on WDM local and wide area networks. He is a member of the National Academy of Engineering and a recipient of the IEEE/OSA John Tyndall, OSA Charles Townes and IEEE/LEOS Quantum Electronics Awards. Since 2004, he has been Adjunct Professor of Electrical Engineering at the University of California, Berkeley. Tingye Li retired from AT&T in 1998 after a 41-year career at Bell Labs and AT&T Labs. His seminal work on laser resonator modes is considered a classic. Since the late 1960s, He and his groups have conducted pioneering studies on lightwave technologies and systems. He led the work on amplified WDM transmission systems and championed their deployment for upgrading network capacity. He is a member of the National Academy of Engineering and a foreign member of the Chinese Academy of Engineering. He is a recipient of the IEEE David Sarnoff Award, IEEE/OSA John Tyndall Award, OSA Ives Medal/Quinn Endowment, AT&T Science and Technology Medal, and IEEE Photonics Award. Alan Willner has worked at AT&T Bell Labs and Bellcore, and he is Professor of Electrical Engineering at the University of Southern California. He received the NSF Presidential Faculty Fellows Award from the White House, Packard Foundation Fellowship, NSF National Young Investigator Award, Fulbright Foundation Senior Scholar, IEEE LEOS Distinguished Lecturer, and USC University-Wide Award for Excellence in Teaching. He is a Fellow of IEEE and OSA, and he has been President of the IEEE LEOS, Editor-in-Chief of the IEEE/OSA J. of Lightwave Technology, Editor-in-Chief of Optics Letters, Co-Chair of the OSA Science & Engineering Council, and General Co-Chair of the Conference on Lasers and Electro-Optics.
Commercial Wireless Circuits and Components Handbook by Mike Golio Pdf
A comprehensive source for microwave and wireless circuit design, the Commercial Wireless Circuits and Components Handbook reviews the fundamentals of transmitters and receivers, then presents detailed chapters on individual circuit types. It also covers packaging, large and small signal characterization, and high volume testing techniques for both devices and circuits. This handbook not only provides important information for engineers working with wireless RF or microwave circuitry, it also serves as an excellent source for those requiring information outside of their area of expertise, such as managers, marketers, and technical support workers who need a better understanding of the fields driving their decisions.
The Legend of Zelda: Hyrule Historia by Eiji Aonuma,Akira Himekawa Pdf
Make sure to check out the other installments in this unparalleled collection of historical information on The Legend of Zelda franchise with the New York Times best selling The Legend of Zelda: Art & Artifacts and The Legend of Zelda: Encyclopedia. Also look for The Legend of Zelda: Breath of the Wild — Creating a Champion for an indepth look at the art, lore, and making of the best selling video game! Dark Horse Books and Nintendo team up to bring you The Legend of Zelda: Hyrule Historia, containing an unparalleled collection of historical information on The Legend of Zelda franchise. This handsome digital book contains never-before-seen concept art, the full history of Hyrule, the official chronology of the games, and much more! Starting with an insightful introduction by the legendary producer and video-game designer of Donkey Kong, Mario, and The Legend of Zelda, Shigeru Miyamoto, this book is crammed full of information about the storied history of Link's adventures from the creators themselves! As a bonus, The Legend of Zelda: Hyrule Historia includes an exclusive comic by the foremost creator of The Legend of Zelda manga — Akira Himekawa!
