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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Institute of Medicine,Committee on Preventing Nicotine Addiction in Children and Youths
Author : Institute of Medicine,Committee on Preventing Nicotine Addiction in Children and Youths Publisher : National Academies Press Page : 321 pages File Size : 45,5 Mb Release : 1994-02-01 Category : Medical ISBN : 9780309051293
Growing Up Tobacco Free by Institute of Medicine,Committee on Preventing Nicotine Addiction in Children and Youths Pdf
Tobacco use kills more people than any other addiction and we know that addiction starts in childhood and youth. We all agree that youths should not smoke, but how can this be accomplished? What prevention messages will they find compelling? What effect does tobacco advertisingâ€"more than $10 million worth every dayâ€"have on youths? Can we responsibly and effectively restrict their access to tobacco products? These questions and more are addressed in Growing Up Tobacco Free, prepared by the Institute of Medicine to help everyone understand the troubling issues surrounding youths and tobacco use. Growing Up Tobacco Free provides a readable explanation of nicotine's effects and the process of addiction, and documents the search for an effective approach to preventing the use of cigarettes, chewing and spitting tobacco, and snuff by children and youths. It covers the results of recent initiatives to limit young people's access to tobacco and discusses approaches to controls or bans on tobacco sales, price sensitivity among adolescents, and arguments for and against taxation as a prevention strategy for tobacco use. The controversial area of tobacco advertising is thoroughly examined. With clear guidelines for public action, everyone can benefit by reading and acting on the messages in this comprehensive and compelling book.
Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction
Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction Publisher : National Academies Press Page : 657 pages File Size : 51,6 Mb Release : 2001-10-17 Category : Medical ISBN : 9780309072823
Clearing the Smoke by Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction Pdf
Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects. Clearing the Smoke addresses the problems in evaluating whether such products actually do reduce the health risks of tobacco use. Within the context of regulating such products, the committee explores key questions: Does the use of such products decrease exposure to harmful substances in tobacco? Is decreased exposure associated with decreased harm to health? Are there surrogate indicators of harm that could be measured quickly enough for regulation of these products? What are the public health implications? This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects. With an attitude of healthy skepticism, Clearing the Smoke will be important to health policy makers, public health officials, medical practitioners, manufacturers and marketers of "reduced-harm" tobacco products, and anyone trying to sort through product claims.
United States. Public Health Service. Office of the Surgeon General
Author : United States. Public Health Service. Office of the Surgeon General Publisher : U.S. Government Printing Office Page : 928 pages File Size : 49,6 Mb Release : 2012 Category : Business & Economics ISBN : UCBK:C095488540
Preventing Tobacco Use Among Youth and Young Adults by United States. Public Health Service. Office of the Surgeon General Pdf
This Surgeon General's report details the causes and the consequences of tobacco use among youth and young adults by focusing on the social, environmental, advertising, and marketing influences that encourage youth and young adults to initiate and sustain tobacco use. This is the first time tobacco data on young adults as a discrete population have been explored in detail. The report also highlights successful strategies to prevent young people from using tobacco
Tobacco has left an indelible mark on the American South, shaping the land and culture throughout the twentieth-century. In the last few decades, advances in technology and shifts in labor and farming policy have altered the way of life for tobacco farmers: family farms have largely been replaced by large-scale operations dependent on hired labor, much of it from other shores. However, the mechanical harvester and the H-2A guestworker did not put an end to tobacco culture but rather sent it in new directions and accelerated the change that has always been part of the farmer’s life. In When Tobacco Was King, Evan Bennett examines the agriculture of the South’s original staple crop in the Old Bright Belt—a diverse region named after the unique bright, or flue-cured, tobacco variety it spawned. He traces the region’s history from Emancipation to the abandonment of federal crop controls in 2004 and highlights the transformations endured by blacks and whites, landowners and tenants, to show how tobacco farmers continued to find meaning and community in their work despite these drastic changes.
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,World Health Organization,International Agency for Research on Cancer
Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,World Health Organization,International Agency for Research on Cancer Publisher : IARC Page : 1476 pages File Size : 40,6 Mb Release : 2004 Category : Medical ISBN : 9283212835
Tobacco Smoke and Involuntary Smoking by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,World Health Organization,International Agency for Research on Cancer Pdf
The IARC Monographs series publishes authoritative independent assessments by international experts of the carcinogenic risks posed to humans by a variety of agents, mixtures and exposures. They are a resource of information for both researchers and national and international authorities. This volume is particularly significant because tobacco smoke not only causes more deaths from cancer than any other known agent; it also causes more deaths from vascular and respiratory diseases. This volume contains all the relevant information on both direct and passive smoking. It is organised by first looking at the nature of agent before collecting the evidence of cancer in humans. This is followed by carcinogenicity studies on animals and then any other data relevant to an evaluation.
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,International Agency for Research on Cancer,World Health Organization
Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,International Agency for Research on Cancer,World Health Organization Publisher : World Health Organization Page : 642 pages File Size : 53,7 Mb Release : 2007 Category : Medical ISBN : 9789283212898
Smokeless Tobacco and Some Tobacco-specific N-nitrosamines by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans,International Agency for Research on Cancer,World Health Organization Pdf
This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary smoking (second-hand smoke or environmental tobacco smoke) (IARC 2004a). Volume 85 summarized the evidence on the carcinogenic risk of chewing betel quid with and without tobacco (IARC 2004b). That volume explored the variety of products chewed in South Asia and other parts of the word that contain areca nut in combination with other ingredients, often including tobacco. In this eighty-ninth volume, the carcinogenic risks associated with the use of smokeless tobacco, including chewing tobacco and snuff, are considered in a first monograph. The second monograph reviews some tobacco-specific nitrosamines. These agents were evaluated earlier in Volume 37 of the Monographs (IARC 1985) and information gathered since that time has been summarized and evaluated.
Author : W. Kip Viscusi Publisher : University of Chicago Press Page : 263 pages File Size : 48,5 Mb Release : 2010-02-15 Category : Law ISBN : 9780226857480
The 1998 out-of-court settlements of litigation by the states against the cigarette industry totaled $243 billion, making it the largest payoff ever in our civil justice system. Two key questions drove the lawsuits and the attendant settlement: Do smokers understand the risks of smoking? And does smoking impose net financial costs on the states? With Smoke-Filled Rooms,W. Kip Viscusi provides unexpected answers to these questions, drawing on an impressive range of data on several topics central to the smoking policy debate. Based on surveys of smokers in the United States and Spain, for instance, he demonstrates that smokers actually overestimate the dangers of smoking, indicating that they are well aware of the risks involved in their choice to smoke. And while smoking does increase medical costs to the states, Viscusi finds that these costs are more than financially balanced by the premature mortality of smokers, which reduces their demands on state pension and health programs, so that, on average, smoking either pays for itself or generates revenues for the states. Viscusi's eye-opening assessment of the tobacco lawsuits also includes policy recommendations that could frame these debates in a more productive way, such as his suggestion that the FDA should develop a rating system for cigarettes and other tobacco products based on their relative safety, thus providing an incentive for tobacco manufacturers to compete among themselves to produce safer cigarettes. Viscusi's hard look at the facts of smoking and its costs runs against conventional thinking. But it is also necessary for an informed and realistic debate about the legal, financial, and social consequences of the tobacco lawsuits. People making $50,000 or more pay .08 percent of their income in cigarette taxes, but people with incomes of less than $10,000 pay 1.62 percenttwenty times as much. The maintenance crew at the Capitol will bear more of the "sin tax" levied on cigarettes than will members of Congress who voted to boost it. Cigarettes are not a financial drain to the U.S. In fact, they are self-financing, as a consequence of smokers' premature mortality. The general public estimates that 47 out of 100 smokers will die from lung cancer because they smoke. Smokers believe that 40 out of 100 will die of the disease. Scientists estimate the actual number of 100 smokers who will die from lung cancer to be between 7 and 13.
Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Public Health Implications of Raising the Minimum Age for Purchasing Tobacco Products
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Public Health Implications of Raising the Minimum Age for Purchasing Tobacco Products Publisher : National Academies Press Page : 398 pages File Size : 42,9 Mb Release : 2015-07-23 Category : Medical ISBN : 9780309316279
Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on the Public Health Implications of Raising the Minimum Age for Purchasing Tobacco Products Pdf
Tobacco use by adolescents and young adults poses serious concerns. Nearly all adults who have ever smoked daily first tried a cigarette before 26 years of age. Current cigarette use among adults is highest among persons aged 21 to 25 years. The parts of the brain most responsible for cognitive and psychosocial maturity continue to develop and change through young adulthood, and adolescent brains are uniquely vulnerable to the effects of nicotine. At the request of the U.S. Food and Drug Administration, Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products considers the likely public health impact of raising the minimum age for purchasing tobacco products. The report reviews the existing literature on tobacco use patterns, developmental biology and psychology, health effects of tobacco use, and the current landscape regarding youth access laws, including minimum age laws and their enforcement. Based on this literature, the report makes conclusions about the likely effect of raising the minimum age to 19, 21, and 25 years on tobacco use initiation. The report also quantifies the accompanying public health outcomes based on findings from two tobacco use simulation models. According to the report, raising the minimum age of legal access to tobacco products, particularly to ages 21 and 25, will lead to substantial reductions in tobacco use, improve the health of Americans across the lifespan, and save lives. Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products will be a valuable reference for federal policy makers and state and local health departments and legislators.
Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Reducing Tobacco Use: Strategies, Barriers, and Consequences
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Reducing Tobacco Use: Strategies, Barriers, and Consequences Publisher : National Academies Press Page : 643 pages File Size : 44,5 Mb Release : 2007-10-27 Category : Medical ISBN : 9780309103824
Ending the Tobacco Problem by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Reducing Tobacco Use: Strategies, Barriers, and Consequences Pdf
The nation has made tremendous progress in reducing tobacco use during the past 40 years. Despite extensive knowledge about successful interventions, however, approximately one-quarter of American adults still smoke. Tobacco-related illnesses and death place a huge burden on our society. Ending the Tobacco Problem generates a blueprint for the nation in the struggle to reduce tobacco use. The report reviews effective prevention and treatment interventions and considers a set of new tobacco control policies for adoption by federal and state governments. Carefully constructed with two distinct parts, the book first provides background information on the history and nature of tobacco use, developing the context for the policy blueprint proposed in the second half of the report. The report documents the extraordinary growth of tobacco use during the first half of the 20th century as well as its subsequent reversal in the mid-1960s (in the wake of findings from the Surgeon General). It also reviews the addictive properties of nicotine, delving into the factors that make it so difficult for people to quit and examines recent trends in tobacco use. In addition, an overview of the development of governmental and nongovernmental tobacco control efforts is provided. After reviewing the ethical grounding of tobacco control, the second half of the book sets forth to present a blueprint for ending the tobacco problem. The book offers broad-reaching recommendations targeting federal, state, local, nonprofit and for-profit entities. This book also identifies the benefits to society when fully implementing effective tobacco control interventions and policies.
IARC Working Group on Reversal of Risk after Quitting Smoking. Meeting,World Health Organization
Author : IARC Working Group on Reversal of Risk after Quitting Smoking. Meeting,World Health Organization Publisher : World Health Organization Page : 376 pages File Size : 53,6 Mb Release : 2007 Category : Antiques & Collectibles ISBN : IND:30000110611005
Reversal of Risk After Quitting Smoking by IARC Working Group on Reversal of Risk after Quitting Smoking. Meeting,World Health Organization Pdf
This is the 11th IARC Handbook of Cancer Prevention, and the first in a series focusing on tobacco control. It reviews the scientific literature and evaluates the evidence on changes in the risk of cancer, coronary heart disease, cerebrovascular disease, abdominal aortic aneurysm, peripheral artery disease and chronic obstructive pulmonary disease observed following smoking cessation. It considers whether the risk of dying from or of developing these diseases decreases after smoking cessation, the time course of the change in risk and whether the risk returns to that of never-smokers? The review and evaluation presented in the Handbook goes on to identify relevant public health and research recommendations.
Nicotine Psychopharmacology by Jack E. Henningfield,Edythe London,Sakire Pogun Pdf
The fact that tobacco ingestion can affect how people feel and think has been known for millennia, placing the plant among those used spiritually, honori?cally, and habitually (Corti 1931; Wilbert 1987). However, the conclusion that nicotine - counted for many of these psychopharmacological effects did not emerge until the nineteenth century (Langley 1905). This was elegantly described by Lewin in 1931 as follows: “The decisive factor in the effects of tobacco, desired or undesired, is nicotine. . . ”(Lewin 1998). The use of nicotine as a pharmacological probe to und- stand physiological functioning at the dawn of the twentieth century was a landmark in the birth of modern neuropharmacology (Limbird 2004; Halliwell 2007), and led the pioneering researcher John Langley to conclude that there must exist some “- ceptive substance” to explain the diverse actions of various substances, including nicotine, when applied to muscle tissue (Langley 1905). Research on tobacco and nicotine progressed throughout the twentieth century, but much of this was from a general pharmacological and toxicological rather than a psychopharmacological perspective (Larson et al. 1961). There was some attention to the effects related to addiction, such as euphoria (Johnston 1941), tolerance (Lewin 1931), and withdrawal (Finnegan et al. 1945), but outside of research supported by the tobacco industry, addiction and psychopharmacology were not major foci for research (Slade et al. 1995; Hurt and Robertson 1998; Henning?eld et al. 2006; Henning?eld and Hartel 1999; Larson et al. 1961).