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Author : IEEE Staff,ieee
Publisher : Unknown
Page : 128 pages
File Size : 52,6 Mb
Release : 2011-03
Category : Electronic
ISBN : 1612848516
Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 42,7 Mb
Release : 2011
Category : Biology
ISBN : OCLC:740063789
Author : Zaheer Ul-Haq,Jeffry D. Madura
Publisher : Elsevier
Page : 444 pages
File Size : 54,8 Mb
Release : 2015-12-16
Category : Science
ISBN : 9781608059782
Frontiers in Computational Chemistry, originally published by Bentham and now distributed by Elsevier, presents the latest research findings and methods in the diverse field of computational chemistry, focusing on molecular modeling techniques used in drug discovery and the drug development process. This includes computer-aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. In Volume 2, the authors continue the compendium with nine additional perspectives in the application of computational methods towards drug design. This volume covers an array of subjects from modern hardware advances that accelerate new antibacterial peptide identification, electronic structure methods that explain how singlet oxygen damages DNA, to QSAR model validation, the application of DFT and DFRT methods on understanding the action of nitrogen mustards, the design of novel prodrugs using molecular mechanics and molecular orbital methods, computational simulations of lipid bilayers, high throughput screening methods, and more. Brings together a wide range of research into a single collection to help researchers keep up with new methods Uniquely focuses on computational chemistry approaches that can accelerate drug design Makes a solid connection between experiment and computation, and the novel application of computational methods in the fields of biology, chemistry, biochemistry, physics, and biophysics
Author : Honghao Gao,Ying Li,Zijian Zhang,Wenbing Zhao
Publisher : Frontiers Media SA
Page : 118 pages
File Size : 40,5 Mb
Release : 2021-06-17
Category : Science
ISBN : 9782889669325
Author : Dmitrij Frishman,Manja Marz
Publisher : CRC Press
Page : 296 pages
File Size : 45,6 Mb
Release : 2021-08-18
Category : Computers
ISBN : 9781000426540
Viruses are the most numerous and deadliest biological entities on the planet, infecting all types of living organisms—from bacteria to human beings. The constantly expanding repertoire of experimental approaches available to study viruses includes both low-throughput techniques, such as imaging and 3D structure determination, and modern OMICS technologies, such as genome sequencing, ribosomal profiling, and RNA structure probing. Bioinformatics of viruses faces significant challenges due to their seemingly unlimited diversity, unusual lifestyle, great variety of replication strategies, compact genome organization, and rapid rate of evolution. At the same time, it also has the potential to deliver decisive clues for developing vaccines and medications against dangerous viral outbreaks, such as the recent coronavirus pandemics. Virus Bioinformatics reviews state-of-the-art bioinformatics algorithms and recent advances in data analysis in virology. FEATURES Contributions from leading international experts in the field Discusses open questions and urgent needs Covers a broad spectrum of topics, including evolution, structure, and function of viruses, including coronaviruses The book will be of great interest to computational biologists wishing to venture into the rapidly advancing field of virus bioinformatics as well as to virologists interested in acquiring basic bioinformatics skills to support their wet lab work.
Author : Siddhartha Kumar Khaitan,Anshul Gupta
Publisher : Springer Science & Business Media
Page : 387 pages
File Size : 52,9 Mb
Release : 2012-09-07
Category : Technology & Engineering
ISBN : 9783642326820
The twin challenge of meeting global energy demands in the face of growing economies and populations and restricting greenhouse gas emissions is one of the most daunting ones that humanity has ever faced. Smart electrical generation and distribution infrastructure will play a crucial role in meeting these challenges. We would need to develop capabilities to handle large volumes of data generated by the power system components like PMUs, DFRs and other data acquisition devices as well as by the capacity to process these data at high resolution via multi-scale and multi-period simulations, cascading and security analysis, interaction between hybrid systems (electric, transport, gas, oil, coal, etc.) and so on, to get meaningful information in real time to ensure a secure, reliable and stable power system grid. Advanced research on development and implementation of market-ready leading-edge high-speed enabling technologies and algorithms for solving real-time, dynamic, resource-critical problems will be required for dynamic security analysis targeted towards successful implementation of Smart Grid initiatives. This books aims to bring together some of the latest research developments as well as thoughts on the future research directions of the high performance computing applications in electric power systems planning, operations, security, markets, and grid integration of alternate sources of energy, etc.
Author : Mitra Basu,Yi Pan,Jianxin Wang
Publisher : Springer
Page : 409 pages
File Size : 43,5 Mb
Release : 2014-06-23
Category : Computers
ISBN : 9783319081717
This book constitutes the refereed proceedings of the 10th International Symposium on Bioinformatics Research and Applications, ISBRA 2014, held in Zhangjiajie, China, in June 2014. The 33 revised full papers and 31 one-page abstracts included in this volume were carefully reviewed and selected from 119 submissions. The papers cover a wide range of topics in bioinformatics and computational biology and their applications including the development of experimental or commercial systems.
Author : Mohamed Ben Ahmed,Anouar Abdelhakim Boudhir
Publisher : Springer
Page : 1046 pages
File Size : 55,6 Mb
Release : 2018-03-21
Category : Technology & Engineering
ISBN : 9783319745008
This proceedings book showcases the latest research work presented at the Second Edition of the Mediterranean Symposium on Smart City Application (SCAMS 2017), which was held in Tangier, Morocco on October 15–27, 2017. It presents original research results, new ideas and practical development experiences that concentrate on both theory and practice. It includes papers from all areas of Smart City Applications, e.g. Smart Mobility, Big Data, Smart Grids, Smart Homes and Buildings, clouds, crowds, mashups, social networks, and security issues. The conference stimulated cutting-edge research discussions among pioneering researchers, scientists, industrial engineers, and students from all around the world. The topics covered in this book also focus on innovative issues at the international level by bringing together experts from different countries. The scope of SCAMS 2017 included methods and practices that combine various emerging internetworking and data technologies to capture, integrate, analyze, mine, annotate, and visualize data in a meaningful and collaborative manner. A series of international workshops were organized as invited sessions during the SCAMS 2017:The 2nd International Workshop on Smart Learning & Innovative EducationsThe 1st International Workshop on Smart HealthcareThe 1st International Workshop on Mathematics for Smart CityThe 1st International Workshop Industry 4.0 and Smart Manufacturing
Author : Gul Agha,Atsushi Igarashi,Naoki Kobayashi,Hidehiko Masuhara,Satoshi Matsuoka,Etsuya Shibayama,Kenjiro Taura
Publisher : Springer
Page : 447 pages
File Size : 47,7 Mb
Release : 2014-09-09
Category : Computers
ISBN : 9783662444719
This Festschrift volume includes a collection of papers written in honor of the accomplishments of Professor Yonezawa on the occasion of his 65th birthday in 2012. With a few exceptions, the papers in this Festschrift were presented at an international symposium celebrating this occasion. Also included are reprints of two of Professor Yonezawa's most influential papers on the programming language ABCL. The volume is a testament strong and lasting impact Professor Yonezawa's research accomplishments as well as the inspiration he has been to colleagues and students alike.
Author : Xiaoli Li,See-Kiong Ng,Jason T L Wang
Publisher : World Scientific
Page : 436 pages
File Size : 48,8 Mb
Release : 2013-11-28
Category : Computers
ISBN : 9789814551021
Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains. Contents:Sequence Analysis:Mining the Sequence Databases for Homology Detection: Application to Recognition of Functions of Trypanosoma brucei brucei Proteins and Drug Targets (G Ramakrishnan, V S Gowri, R Mudgal, N R Chandra and N Srinivasan)Identification of Genes and Their Regulatory Regions Based on Multiple Physical and Structural Properties of a DNA Sequence (Xi Yang, Nancy Yu Song and Hong Yan)Mining Genomic Sequence Data for Related Sequences Using Pairwise Statistical Significance (Yuhong Zhang and Yunbo Rao)Biological Network Mining:Indexing for Similarity Queries on Biological Networks (Günhan Gülsoy, Md Mahmudul Hasan, Yusuf Kavurucu and Tamer Kahveci)Theory and Method of Completion for a Boolean Regulatory Network Using Observed Data (Takeyuki Tamura and Tatsuya Akutsu)Mining Frequent Subgraph Patterns for Classifying Biological Data (Saeed Salem)On the Integration of Prior Knowledge in the Inference of Regulatory Networks (Catharina Olsen, Benjamin Haibe-Kains, John Quackenbush and Gianluca Bontempi)Classification, Trend Analysis and 3D Medical Images:Classification and Its Application to Drug-Target Prediction (Jian-Ping Mei, Chee-Keong Kwoh, Peng Yang and Xiao-Li Li)Characterization and Prediction of Human Protein-Protein Interactions (Yi Xiong, Dan Syzmanski and Daisuke Kihara)Trend Analysis (Wen-Chuan Xie, Miao He and Jake Yue Chen)Data Acquisition and Preprocessing on Three Dimensional Medical Images (Yuhua Jiao, Liang Chen and Jin Chen)Text Mining and Its Biomedical Applications:Text Mining in Biomedicine and Healthcare (Hong-Jie Dai, Chi-Yang Wu, Richard Tzong-Han Tsai and Wen-Lian Hsu)Learning to Rank Biomedical Documents with Only Positive and Unlabeled Examples: A Case Study (Mingzhu Zhu, Yi-Fang Brook Wu, Meghana Samir Vasavada and Jason T L Wang)Automated Mining of Disease-Specific Protein Interaction Networks Based on Biomedical Literature (Rajesh Chowdhary, Boris R Jankovic, Rachel V Stankowski, John A C Archer, Xiangliang Zhang, Xin Gao, Vladimir B Bajic) Readership: Students, professionals, those who perform biological, medical and bioinformatics research. Keywords:Healthcare;Data Mining;Biological Data Mining;Protein Interactions;Gene Regulation;Text Mining;Biological Literature Mining;Drug Discovery;Disease Network;Biological Network;Graph Mining;Sequence Analysis;Structure Analysis;Trend Analysis;Medical ImagesKey Features:Each chapter of this book will include a section to introduce a specific class of data mining techniques, which will be written in a tutorial style so that even non-computational readers such as biologists and healthcare researchers can appreciate themThe book will disseminate the impact research results and best practices of data mining approaches to the cross-disciplinary researchers and practitioners from both the data mining disciplines and the life sciences domains. The authors of the book will be well-known data mining experts, bioinformaticians and cliniciansEach chapter will also provide a detailed description on how to apply the data mining techniques in real-world biological and clinical applications. Thus, readers of this book can easily appreciate the computational techniques and how they can be used to address their own research issues
Author : E.H. D'Hollander
Publisher : IOS Press
Page : 228 pages
File Size : 45,6 Mb
Release : 2013-10-22
Category : Computers
ISBN : 9781614993247
The US, Europe, Japan and China are racing to develop the next generation of supercomputers – exascale machines capable of 10 to the 18th power calculations a second – by 2020. But the barriers are daunting: the challenge is to change the paradigm of high-performance computing. The 2012 biennial high performance workshop, held in Cetraro, Italy in June 2012, focused on the challenges facing the computing research community to reach exascale performance in the next decade. This book presents papers from this workshop, arranged into four major topics: energy, scalability, new architectural concepts and programming of heterogeneous computing systems. Chapter 1 introduces the status of present supercomputers, which are still about two orders of magnitude separated from the exascale mark. Chapter 2 examines energy demands, a major limiting factor of today's fastest supercomputers; the quantum leap in performance required for exascale computing will require a shift in architectures and technology. In Chapter 3, scalable computer paradigms for dense linear algebra on massive heterogeneous systems are presented, and Chapter 4 discusses architectural concepts. Finally, Chapter 5 addresses the programming of heterogeneous systems. This book will be of interest to all those wishing to understand how the development of modern supercomputers is set to advance in the next decade.
Author : Shuo Li,João Manuel R. S. Tavares
Publisher : Springer Science & Business Media
Page : 442 pages
File Size : 50,5 Mb
Release : 2014-01-28
Category : Technology & Engineering
ISBN : 9783319038131
This book contains thirteen contributions from invited experts of international recognition addressing important issues in shape analysis in medical image analysis, including techniques for image segmentation, registration, modelling and classification and applications in biology, as well as in cardiac, brain, spine, chest, lung and clinical practice. This volume treats topics such as for example, anatomic and functional shape representation and matching; shape-based medical image segmentation; shape registration; statistical shape analysis; shape deformation; shape-based abnormity detection; shape tracking and longitudinal shape analysis; machine learning for shape modeling and analysis; shape-based computer-aided-diagnosis; shape-based medical navigation; benchmark and validation of shape representation, analysis and modeling algorithms. This work will be of interest to researchers, students and manufacturers in the fields of artificial intelligence, bioengineering, biomechanics, computational mechanics, computational vision, computer sciences, human motion, mathematics, medical imaging, medicine, pattern recognition and physics.
Author : Ervin Sejdic,Tiago H. Falk
Publisher : CRC Press
Page : 624 pages
File Size : 42,5 Mb
Release : 2018-07-04
Category : Medical
ISBN : 9781498773461
Within the healthcare domain, big data is defined as any ``high volume, high diversity biological, clinical, environmental, and lifestyle information collected from single individuals to large cohorts, in relation to their health and wellness status, at one or several time points.'' Such data is crucial because within it lies vast amounts of invaluable information that could potentially change a patient's life, opening doors to alternate therapies, drugs, and diagnostic tools. Signal Processing and Machine Learning for Biomedical Big Data thus discusses modalities; the numerous ways in which this data is captured via sensors; and various sample rates and dimensionalities. Capturing, analyzing, storing, and visualizing such massive data has required new shifts in signal processing paradigms and new ways of combining signal processing with machine learning tools. This book covers several of these aspects in two ways: firstly, through theoretical signal processing chapters where tools aimed at big data (be it biomedical or otherwise) are described; and, secondly, through application-driven chapters focusing on existing applications of signal processing and machine learning for big biomedical data. This text aimed at the curious researcher working in the field, as well as undergraduate and graduate students eager to learn how signal processing can help with big data analysis. It is the hope of Drs. Sejdic and Falk that this book will bring together signal processing and machine learning researchers to unlock existing bottlenecks within the healthcare field, thereby improving patient quality-of-life. Provides an overview of recent state-of-the-art signal processing and machine learning algorithms for biomedical big data, including applications in the neuroimaging, cardiac, retinal, genomic, sleep, patient outcome prediction, critical care, and rehabilitation domains. Provides contributed chapters from world leaders in the fields of big data and signal processing, covering topics such as data quality, data compression, statistical and graph signal processing techniques, and deep learning and their applications within the biomedical sphere. This book’s material covers how expert domain knowledge can be used to advance signal processing and machine learning for biomedical big data applications.
Author : Mohd Saberi Mohamad,Loris Nanni,Miguel P. Rocha,Florentino Fdez-Riverola
Publisher : Springer Science & Business Media
Page : 153 pages
File Size : 53,6 Mb
Release : 2013-04-19
Category : Technology & Engineering
ISBN : 9783319005782
The growth in the Bioinformatics and Computational Biology fields over the last few years has been remarkable and the trend is to increase its pace. In fact, the need for computational techniques that can efficiently handle the huge amounts of data produced by the new experimental techniques in Biology is still increasing driven by new advances in Next Generation Sequencing, several types of the so called omics data and image acquisition, just to name a few. The analysis of the datasets that produces and its integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Within this scenario of increasing data availability, Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. Indeed, Biology is more and more a science of information requiring tools from the computational sciences. In the last few years, we have seen the surge of a new generation of interdisciplinary scientists that have a strong background in the biological and computational sciences. In this context, the interaction of researchers from different scientific fields is, more than ever, of foremost importance boosting the research efforts in the field and contributing to the education of a new generation of Bioinformatics scientists. PACBB‘13 hopes to contribute to this effort promoting this fruitful interaction. PACBB'13 technical program included 19 papers from a submission pool of 32 papers spanning many different sub-fields in Bioinformatics and Computational Biology. Therefore, the conference will certainly have promoted the interaction of scientists from diverse research groups and with a distinct background (computer scientists, mathematicians, biologists). The scientific content will certainly be challenging and will promote the improvement of the work that is being developed by each of the participants.
Author : IEEE Staff
Publisher : Unknown
Page : 128 pages
File Size : 47,5 Mb
Release : 2013-06-12
Category : Electronic
ISBN : 1479907154