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A Guide to the Human Genome Project by Susan L. Speaker,M. Susan Lindee,Elizabeth Hanson Pdf
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.
Curiosity Guides: The Human Genome by John Quackenbush Pdf
The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
A Short Guide to the Human Genome by Stewart Scherer Pdf
Although the human genome has been sequenced, it can be difficult to find answers to seemingly simple questions about its characteristics. How many genes are there? Which genes are commonly associated with genetic diseases? How many DNA-binding proteins, mobile elements, or kinases are present? What are the major differences between human proteins and those of other species? This convenient handbook, written in question-and-answer format, allows researchers and teachers alike access to basic facts about the human genome.
Curiosity Guides: The Human Genome by John Quackenbush Pdf
The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
Curiosity Guides: The Human Genome by John Quackenbush Pdf
The DNA sequence that comprises the human genome--the genetic blueprint found in each of our cells--is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new millennium, the feat electrified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, including Alzheimer's, cancer, diabetes, and Parkinson's. Yet what is arguably the most important discovery of our time has also opened a Pandora's box of questions about who we are as humans and how the unique information stored in our genomes can and might be used, making it all the more important for everyone to understand the new science of genomics. In the CURIOSITY GUIDE TO THE HUMAN GENOME, Dr. John Quackenbush, a renowned scientist and professor, conducts a fascinating tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today. With a clear and engaging narrative style, he demystifies the fundamental principles of genetics and molecular biology, including the astounding ways in which genes function, alone or together with other genes and the environment, to either sustain life or trigger disease. In addition, Dr. Quackenbush goes beyond medicine to examine how DNA-sequencing technology is changing how we think of ourselves as a species by providing new insights about our earliest ancestors and reconfirming our inextricable link to all life on earth. Finally, he explores the legal and ethical questions surrounding such controversial topics as stem cell research, prenatal testing, forensics, and cloning, making this volume of the Curiosity Guides series an indispensable resource for navigating our brave new genomic world.
The Human Genome by Julia E. Richards,R. Scott Hawley Pdf
Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers
The DNA sequence that comprises the human genome - the genetic blueprint found in each of our cells - is undoubtedly the greatest code ever to be broken. Completed at the dawn of a new milennium, the feat electified both the scientific community and the general public with its tantalizing promise of new and better treatments for countless diseases, includein Alzheimer's, cancer, diabetes, and Parkinson's.
The Human Genome Project in College Curriculum by Aine Donovan,Ronald Michael Green Pdf
Begun formally in 1990, the U.S. Human Genome Project's (HGP) goals were to identify all the 20,000 to 25,000 genes in human DNA, determine the sequences of the three billion chemical base pairs that make up human DNA, store this information in databases, improve tools for data analysis, and transfer related technologies to the private sector. It was the first large scientific undertaking to address potential issues that arose from project data, and opened up vast possibilities for the use of genetic data and the alteration of our genetic makeup. This volume is the first to address the diverse range of ethical issues arising from the HGP, and enables professors to bring this critically important topic to life in the classroom. ';
Guide to Human Genome Computing by Martin J. Bishop Pdf
The Guide to Human Genome Computing is invaluable to scientists who wish to make use of the powerful computing tools now available to assist them in the field of human genome analysis. This book clearly explains access and use of sequence databases, and presents the various computer packages used to analyze DNA sequences, measure linkage analysis, compare and align DNA sequences from different genes or organisms, and infer structural and functional information about proteins from sequence data. This Second Edition contains completely updated material. Rather than a revision of the previous volume, the Second Edition is essentially a new book, based on the subjects which will be of interest over the coming years. This new book is international, both in scope and authorship. Computing resources for the following are clearly explained: Internet resources - databases etc. Genetic analysis Sib-pair studies Comparative mapping Radiation hybrids Sequence ready clone maps Human genome sequencing ESTs Gene prediction Gene expression
The Human Genome Project was a groundbreaking, life-altering development of the late 20th century and a major evolution in science and medicine. Readers of this remarkable volume will follow the scientists of the international, collaborative research program as they map the human genome. They'll learn about the science behind the project as well as the scientific and medical possibilities opened by it. Vivid photographs support the fascinating text, and sidebars, fact boxes, and captions enrich your reader's experience.
National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome
Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome Publisher : National Academies Press Page : 128 pages File Size : 46,8 Mb Release : 1988-01-01 Category : Science ISBN : 9780309038409
Mapping and Sequencing the Human Genome by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome Pdf
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
The Human Genome Sourcebook by Tara Acharya,Neeraja Sankaran Pdf
This is not another book about the Human Genome Project. It is, however, about the human genome: the genes that make it up, what the genes do when they are acting properly, and what happens when these genes are damaged. Designed for today's reader who demands quick answers to a wide range of questions, this book is intended to offer the nonspecialist a first-stop, but fairly detailed, guide to the genome. The information it provides is given context: namely, the basic scientific principles of genome research, the new knowledge unearthed or created by this research, and the social and ethical implications of this knowledge.
Author : Charles R. Cantor,Cassandra L. Smith Publisher : John Wiley & Sons Page : 621 pages File Size : 43,7 Mb Release : 2004-01-06 Category : Science ISBN : 9780471461869
Genomics by Charles R. Cantor,Cassandra L. Smith Pdf
A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features: * Topical organization within chapters for easy reference * A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters * Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids * Informed predictions for the future of DNA sequencing