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Accelerated Aging: Photochemical and Thermal Aspects represents the culmination of more than 40 years of research by noted scientist Robert L. Feller. The book focuses on the long-term performance of materials such as wool, dyes, and organic compounds; their resistance to change when exposed to environmental factors such as oxygen, ozone, moisture, heat, and light; and their physical durability with handling and use over time. Processes of deterioration are discussed based on speeded-up laboratory studies designed to clarify the chemical reactions involved and their physical consequences.
Fast Track to Aging Backwards by Miranda Esmonde-White Pdf
Drawing on her groundbreaking anti-aging movement principles, bestselling fitness expert Miranda Esmonde-White walks you through 6 ways to rejuvenate your body and mind, paired with 30 days of stretching-and-strengthening workouts that effectively reverse the aging process. Miranda Esmonde-White has already given us the Bible on movement as a way to reverse aging with her New York Times and Globe and Mail bestseller Aging Backwards. But getting started on something that will change your life is always the hardest part! The Fast Track to Aging Backwards is Miranda's master class on how to begin her healing, revitalizing and scientifically endorsed programme of stretching and strengthening--and how to make it stick. First she outlines, step by step, 6 ways to change your attitude to aging and reverse its effects, from describing helpful small changes to your daily routine that will help you form new habits; to how to find the balance between moving like the Tin Man and flopping like the Scarecrow; to showing that for maximum painfree living, our bodies need a gentle approach to exercising that is all about respecting the way our bodies are designed to move. As Miranda says, "Relaxation is the new strengthening." Exclusively for this book, she has also created 4 workouts designed to carry you every step of the way through the first month of her programme, targeting every part of your body. Laid out with clear instructions, black-and-white photos and insider's tips on how to make every movement count, these workouts will give you the edge you need to quickly achieve your best results. The Fast Track to Aging Backwards is a countdown to a healthier and more youthful you.
Practical Geriatric Oncology by Arti Hurria,Harvey Jay Cohen Pdf
The risk of cancer increases with age, and the number of older adults seeking treatment is increasing dramatically in line with the aging population. The care of older patients differs from that of younger adults because of differences in the biology of the tumor, age-related differences in host physiology, comorbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Practical Geriatric Oncology is a comprehensive, evidence-based text that synthesizes the growing literature in this field and provides practical guidelines to the care of older adults with cancer. Coverage includes patient assessment, management of solid tumors and hematologic malignancies, the impact of age on the pharmacology of cancer therapy, surgical oncology and radiation oncology in the older adult, symptom management and supportive care. In addition to serving as core reading for oncologists and hematologists, the book will also be a useful work for other healthcare professionals who provide oncology care, including surgeons, radiation oncologists, palliative care doctors, primary care providers, geriatricians and nurses.
Author : Raymond Francis Publisher : Simon and Schuster Page : 336 pages File Size : 44,5 Mb Release : 2013-10-02 Category : Health & Fitness ISBN : 9780757317330
Ray Francis' first book, Never Be Sick Again, helped thousands of people put their "incurable" diseases into remission and enabled thousands more to shed excess weight, improve their cholesterol profiles, and achieve peak immunity from disease. Now Francis brings his revolutionary approach to anyone who wants to enjoy robust health and wellness and reverse accelerated aging. As Francis explains, just like an automobile, the body ages as a result of accumulated repair deficits, or a lack of maintenance. Fortunately, the human body is a self-repairing system, and in this latest book, Francis shows readers how to stay in good repair and keep the aging process at bay. His revolutionary approach counters the one-size-fits-all approach of most conventional anti-aging treatments on the market by targeting specific imbalances that manifest through "aging" symptoms. Botox injections, plastic surgery, and even hormone-replacement therapies don't yield meaningful results because they fail to activate the body's self-repair mechanisms; what's more, sometimes these treatments compound the problem by introducing additional toxins into the body. Never Feel Old Again provides a fundamental understanding of why we experience accelerated aging and teaches readers to look and feel their best and be healthy at any age.
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
Endocrine and Metabolic Late Effects in Cancer Survivors by Francesco Felicetti (Oncologist),Enrico Brignardello,Hanneke M. van Santen Pdf
This book analyzes in detail all aspects related to endocrine and metabolic late effects observed in patients treated for cancer, both in childhood and adulthood. The chapters focusing on the possible pathogenic mechanisms of late effects (i.e., premature aging and chronic inflammation) and on bone health in cancer survivors are particularly interesting and innovative. The volume also deals with hypothalamic-pituitary, thyroid and gonadal disorders, including infertility and how to prevent it. Finally, the relationship between metabolic alterations and cardiovascular diseases in cancer survivors is addressed. Thanks to advances in cancer treatment and supportive care, the five-year survival rate of cancer patients is constantly increasing. However, this undisputable success of medicine has a flip side: the late adverse effects of anticancer therapies. Pediatric oncologists were the first to cope with late complications of treatments, but today also adult oncologists and onco-hematologists recognize the relevance of this issue. Even though late effects observed in cancer survivors can affect any organ or system, endocrine and metabolic dysfunctions are the most frequently reported. Endocrine complications rarely influence life expectancy of cancer survivors, but they can significantly impact morbidity and quality of life. Among endocrine adverse effects, severe hypothalamic damage may be considered the most harmful in survivors, leading to morbid obesity, propensity to metabolic syndrome and cardiovascular disease. This book aims to disseminate the knowledge about endocrine and metabolic adverse effects of cancer therapies and about survivorship care. Since the number of cancer survivors is steadily growing in the general population, this publication is intended not only for endocrinologists but also for oncologists, onco-hematologists, internists, pediatric specialists in those areas and general practitioners, with the aim to better counsel and monitor cancer survivors.
Biochemistry and Cell Biology of Ageing: Part II Clinical Science by J. Robin Harris,Viktor I. Korolchuk Pdf
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Ageing Studies and Lifetime Extension of Materials by Les Mallinson Pdf
The first International Conference on Ageing Studies and Lifetime Extension of Materials was held on th July 12-14 , 1999 at St. Catherine's College, Oxford, United Kingdom. Over 230 delegates attended during the three days and heard nearly ninety papers, together with over thirty poster presentations. Sixteen of these papers were keynotes from invited speakers eminent in their field of research. The proceedings were organised into six separate sessions: observation and understanding of real-time and accelerated ageing; experimental techniques; modelling and theoretical studies; lifetime prediction and validation; lifetime extension; and material design for ageing. In doing this, it was hoped to cover most issues of scientific concern inthefield ofmaterials ageing. One important aspect was that the conference did not concentrateon any particular group or type ofmaterial; rather the aim was to attract contributions from workers engaged in ageing studies with as wide a range of materials as possible. In this way, it was hoped that delegates could interactwith and learnfrom those whom they perhapswould not normally come across and that metallurgists could learn from polymer scientists, ceramicists could talk to modellers, and so on, in this important field. A read through the diverse papers contained within these proceedings will confirm that this aim was happily satisfied. Why hold such a meeting? In the modem world, engineered systems are expected to last longer.
Early Vascular Aging (EVA) by Pedro Guimarães Cunha,Pierre Boutouyrie,Michael Hecht Olsen,Peter M Nilsson,Stephane Laurent Pdf
Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations
Medical Device Packaging Handbook, Revised and Expanded by Max Sherman Pdf
This volume details current developments in industry practices and standards relating to medical device packaging. This edition offers entirely new as well as revised chapters on packaging materials, package validation and methods and integrity testing, bar-coding technology, environmentally sound packaging and disposal procedures, storage autoclave sytems, international standards, customer needs, regulatory aspects, and more.
Despite decades of attention on building a global HIV research and programming agenda, HIV in older populations has generally been neglected until recently. This new book focuses on HIV and aging in the context of ageism with regard to prevention, treatment guidelines, funding, and the engagement of communities and health and social service organizations. The lack of perceived HIV risk in late adulthood among older people themselves, as well on the part of providers and society in general, has led to a lack of investment in education, testing, and programmatic responses. Ageism perpetuates the invisibility of older adults and, in turn, renders current medical and social service systems unprepared to respond to patients’ needs. While ageism may lead to some advantages – discounts for services, for example – it is the negative aspects that must be addressed when determining the appropriate community-level response to the epidemic.
National Research Council,Division on Engineering and Physical Sciences,Commission on Engineering and Technical Systems,Board on Infrastructure and the Constructed Environment
Author : National Research Council,Division on Engineering and Physical Sciences,Commission on Engineering and Technical Systems,Board on Infrastructure and the Constructed Environment Publisher : National Academies Press Page : 43 pages File Size : 55,8 Mb Release : 1999-06-29 Category : Technology & Engineering ISBN : 9780309184120
Research Agenda for Test Methods and Models to Simulate the Accelerated Aging of Infrastructure Materials by National Research Council,Division on Engineering and Physical Sciences,Commission on Engineering and Technical Systems,Board on Infrastructure and the Constructed Environment Pdf
In the next several decades, a significant percentage of the country's transportation, communications, environmental, and power system infrastructures, as well as public buildings and facilities, will have to be renewed or replaced. Next-generation infrastructure will have to meet very high expectations in terms of durability, constructability, performance, and life-cycle cost. One way of meeting future expectations will be through improved, high-performance materials, but before new materials can be confidently deployed in the field, a thorough and comprehensive understanding must be developed of their long-term performance in a variety of applications and physical environments. The National Science Foundation (NSF) has launched an initiative to promote the development of innovative short-term laboratory or in-situ tests for making accurate, reliable predictions of the long-term performance of materials and requested that the National Research Council (NRC) conduct a workshop as a reconnaissance-level assessment of models and methods that are being used, or potentially could be used, to determine the long-term performance of infrastructure materials and components.
Artificial Aging as a Predictor of Paper's Future Useful Life by Helmut Bansa,Hans-H. Hofer Pdf
An experiment with the artificial aging of paper which--in contrast with the usual practice--was carried out at relatively low temperatures (i.e., 50-95 degrees Celsius), and not on laboratory handsheets, but on naturally aged paper from the commercial production of four centuries, produced results justifying the thesis that there may be at best an accidental agreement between the results of artificial aging at high temperatures and natural aging. The chemical processes that take place as paper ages appear to take different temperature-specific courses, so that it is not possible to draw any conclusions from short-term expiration at one (elevated) temperature about the long-term expiration at another (room) temperature. If artificial aging cannot be dispensed with despite this uncertainty, aging should take place at 80 degrees Celsius and 65% relative humidity. The data collected are displayed in 24 tables and 10 figures. (Author/SD)