Adequate Hla Matching In Keratoplasty

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Adequate HLA Matching in Keratoplasty

Author : Rainer Sundmacher
Publisher : Karger Medical and Scientific Publishers
Page : 108 pages
File Size : 53,9 Mb
Release : 2003
Category : Medical
ISBN : 9783805574877

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Adequate HLA Matching in Keratoplasty by Rainer Sundmacher Pdf

Immunologic privilege of the cornea and anterior chamber has, in most cases, been believed to be a sufficient guarantee for survival of the donor cornea. If this failed, it was thought that adjunctive immunomodulating agents would compensate. But the question of how to care for better tolerance and safer long-term survival of corneal grafts after withdrawal of a potent immunomodulating shield still remained unanswered. The answer is human leukocyte antigens (HLA) matching. In this volume, immunological and clinical aspects are discussed by renowned clinical and experimental immunologists as well as experienced keratoplasty surgeons. These experts conclude that HLA matching is, in fact, a valuable adjunct for long-term survival of corneal grafts not only in those at high risk but notably also in patients at normal risk. This volume opens new pathways towards the successful application of HLA matching to keratoplasty surgeons, experimental and clinical immunologists and cornea bank officers, at the same time acting as an aid to ophthalmologists when finding the basis to adequately advise their keratoplasty patients.

Modern Keratoplasty

Author : Jorge L. Alió,Jorge L. Alió del Barrio
Publisher : Springer Nature
Page : 521 pages
File Size : 47,8 Mb
Release : 2023-10-27
Category : Medical
ISBN : 9783031324086

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Modern Keratoplasty by Jorge L. Alió,Jorge L. Alió del Barrio Pdf

​Keratoplasty techniques have evolved in the last 15 years into a variety of forms, which have diversified the previous monographic presence of the penetrating keratoplasty technique. The development of anterior lamellar graft (DALK), and posterior lamellar graft (DSAEK), makes an important change in the approach to lamellar surgery. Later on, the appearance of DMEK and superficial lamellar keratectomy broadened the spectrum. Today, intralamellar surgery has evolved with a number of techniques that involve stromal enhancement with biologically active or acellular corneal laminas from donors, customized lenticles from SMILE surgeries or customized by corneal topography, and more recently, corneal regeneration of the stroma by advanced techniques using mesenchymal stem cells. This book offers a comprehensive overview of modern keratoplasty techniques, the technology, surgical skills, and outcomes. It highlights the practical uses of keratoplasty for all cornea surgeons and anterior segment surgeons. The book is divided into sections, each covering a specific type of keratoplasty, including chapters on innovations within each surgery type. The goal of this book is to unify all recent knowledge about the different keratoplasty techniques and outcomes, creating a one-stop resource for ophthalmaolgy surgeons. Modern Keratoplasty is a must-have resource for corneal specialists and surgeons, anterior segment surgeons, refractive surgeons, cataract surgeons, residents, fellows, and corneal researchers.

Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders

Author : Uwe Pleyer,Jorge L. Alió,Talin Barisani-Asenbauer,Phuc Le Hoang,Narsing A. Rao
Publisher : Springer
Page : 244 pages
File Size : 46,7 Mb
Release : 2014-05-23
Category : Medical
ISBN : 9783642543500

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Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders by Uwe Pleyer,Jorge L. Alió,Talin Barisani-Asenbauer,Phuc Le Hoang,Narsing A. Rao Pdf

These guidelines, compiled by a panel of clinicians and scientists with a high level of expertise, aim to provide readers with the most up-to-date and comprehensive instructions on the treatment and prevention of ocular inflammation. All of the recommendations are explicitly linked to supporting evidence and graded according to the strength of that evidence and the editors have made every effort to ensure that chapters are of a consistently high methodological quality. The guidelines for each treatment include dose and the frequency and mode of delivery. Significant side-effects of treatment are identified and distinguished from those of the disease in question. Suggestions are presented for the prevention both of the disease itself and of the treatment-related complications. In addition, likely future directions in treatment and prevention are identified. These guidelines will be of great practical value for all clinicians and clinical scientists with an interest in the subject.

Eye Banking

Author : T. Bredehorn,Gernot Duncker,W. John Armitage
Publisher : Karger Medical and Scientific Publishers
Page : 150 pages
File Size : 49,7 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9783805591249

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Eye Banking by T. Bredehorn,Gernot Duncker,W. John Armitage Pdf

Corneal transplantation has been performed with increasing success for more than 100 years. In the last 20 years, standards, outcomes and developments in the field of corneal transplantation and eye banking have been discussed at the annual meetings of the European Eye Bank Association (EEBA) to share and promote good practice and guarantee a high level of safety for the recipients. The EEBA standards for donor selection and eye banking provide professional advice and guidance to eye banks and corneal surgeons.This book highlights the history and development of eye banking and all significant steps including the donation, processing and distribution of corneas for transplantation. Additional contributions on the sclera, amnion and retinal pigment epithelium provide further insights into ocular surgery and the future potential for transplantation. This book contributes the essentials in eye banking activities for ophthalmologists and eye bankers as well as for regulatory and legislative authorities.

Uveitis and Immunological Disorders

Author : Uwe Pleyer,C. Stephen Foster
Publisher : Springer Science & Business Media
Page : 240 pages
File Size : 41,7 Mb
Release : 2006-10-28
Category : Medical
ISBN : 9783540307983

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Uveitis and Immunological Disorders by Uwe Pleyer,C. Stephen Foster Pdf

This second Uveitis volume provides the ophthalmologist with the most current understanding of the pathogenesis of the most frequent immune-mediated disorders of the eye and a practical approach to these diseases. It fills the gap between textbooks and original research publications and focuses on clinical aspects of inflammatory eye diseases. It covers a broad spectrum, including diseases affecting the conjunctiva, sclera and cornea, as well as intraocular inflammation, and it includes basic research aspects, such as immune mechanisms and genetics. The book is easy to read with highly structured core messages and summaries for the clinician.

50 Studies Every Ophthalmologist Should Know

Author : Alan Penman,Kimberley Crowder,William M. Watkins
Publisher : Oxford University Press, USA
Page : 337 pages
File Size : 41,6 Mb
Release : 2020
Category : Medical
ISBN : 9780190050726

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50 Studies Every Ophthalmologist Should Know by Alan Penman,Kimberley Crowder,William M. Watkins Pdf

"50 Ophthalmology Studies Every Ophthalmologist Should Know" succinctly summarizes the most important and clinically relevant studies published in the mainstream ophthalmology literature in the past 40 years. Emphasis has been placed on landmark studies, rather than studies that are most frequently cited, which changed thinking and practice in the field. Most are randomized controlled trials that have helped shape current ophthalmology practice guidelines; However, some important observational (cohort, case-control, and descriptive) studies are also included. The book is divided into 7 sections, corresponding to anatomical segment or disease of the eye (cornea, cataract, glaucoma, vitreoretinal, macula, uveal tract, and orbit/eyelids/extraocular muscles/optic nerve). Each chapter finishes with an illustrative clinical case. Ophthalmology has a particular relevance to physicians working in primary care, internal medicine, neurology, neurosurgery, pediatrics, and emergency medicine. For ophthalmologists, each chapter has a reference to the relevant section of the practice guidelines of the American Academy of Ophthalmology"--

Corneal Transplantation

Author : John V. Forrester,Lucia Kuffova
Publisher : World Scientific
Page : 206 pages
File Size : 54,9 Mb
Release : 2004
Category : Medical
ISBN : 9781860944499

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Corneal Transplantation by John V. Forrester,Lucia Kuffova Pdf

- Concise but comprehensive guidebook/handbook - Current and translational information - New concepts of rejection and tolerance - Multimedia display of microsurgical technique

Corneal Surgery

Author : Frederick S. Brightbill
Publisher : Elsevier Health Sciences
Page : 970 pages
File Size : 46,7 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9780323048354

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Corneal Surgery by Frederick S. Brightbill Pdf

Part. 1 Introduction to corneal function and surgery -- Part. 2 Testing and measuring corneal function -- Part. 3 Ocular surface surgery and reconstruction -- Part. 4 Techniques in corneal transplantation -- Part. 5 Special situations in corneal surgery -- Part. 6 Surgical correction of refractive errors.

Color Atlas of Herpetic Eye Disease

Author : Rainer Sundmacher
Publisher : Springer Science & Business Media
Page : 183 pages
File Size : 55,5 Mb
Release : 2008-11-14
Category : Medical
ISBN : 9783540694632

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Color Atlas of Herpetic Eye Disease by Rainer Sundmacher Pdf

This well-structured atlas offers practical advice for the recognition and management of each Herpetic Eye problem. It is based on nearly four decades of practical and scientific work and experience with follow-ups in thousands of herpes patients.

Cornea and External Eye Disease

Author : Thomas Reinhard,Frank Larkin
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 49,6 Mb
Release : 2006-01-28
Category : Medical
ISBN : 9783540312260

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Cornea and External Eye Disease by Thomas Reinhard,Frank Larkin Pdf

"Essentials in Ophthalmology" is a new review series covering all of ophthalmology categorized in eight subspecialties. It will be published quarterly, thus each subspecialty will be reviewed biannually. Given the multiplicity of medical publications already available, why is a new series needed? Consider that the half-life of medical knowledge is estimated to be around 5 years. Moreover, it can be as long as 8 years between the first description of a medical innovation in a peer-reviewed scientific journal and publication in a medical textbook. A series that narrows this time span between journal and textbook would provide a more rapid and efficient transfer of medical knowledge into clinical practice, and enhance care of our patients.

Cornea E-Book

Author : Jay H. Krachmer,Mark J Mannis,Edward J Holland
Publisher : Elsevier Health Sciences
Page : 1997 pages
File Size : 40,7 Mb
Release : 2010-10-27
Category : Medical
ISBN : 9780323081177

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Cornea E-Book by Jay H. Krachmer,Mark J Mannis,Edward J Holland Pdf

Cornea, edited by Drs. Krachmer, Mannis & Holland, is the only truly comprehensive clinical reference available that covers external disease, anterior uveitis, and the expanding range of contemporary corneal surgery. In this Third Edition, state-of-the-art coverage, 25 brand-new chapters, and 45 new videos provide expert guidance on performing femtosecond-assisted penetrating keratoplasty, DSAEK, deep anterior lamellar keratoplasty, and many other cutting-edge techniques. Plus, you’ll have easy access to the complete contents and illustrations online at expertconsult. Overcome any clinical challenge related to the cornea, external disease, anterior uveitis, and the expanding range of contemporary corneal surgery with the most complete, authoritative guidance source available. Get superb visual guidance with exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs. Access the complete contents and illustrations online at expertconsult. Make optimal use of Anterior Segment OCT to plan and choose treatment options and assess post-operative recovery. Master the latest surgical techniques—including femtosecond-assisted penetrating keratoplasty, DSAEK, and deep anterior lamellar keratoplasty—thanks to 25 brand-new chapters and 45 new videos on DVD (a total of 3 hours running time). Understand the full spectrum of corneal diseases with coverage of the new corneal dystrophy classification that incoporates current genetic, clinical, and pathologic information.

Corneal Transplantation

Author : Namrata Sharma,Ritu Nagpal,Rasik B Vajpayee
Publisher : Jaypee Brothers Medical Publishers
Page : 591 pages
File Size : 46,7 Mb
Release : 2022-11-09
Category : Medical
ISBN : 9789389587227

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Corneal Transplantation by Namrata Sharma,Ritu Nagpal,Rasik B Vajpayee Pdf

The cornea is the clear, outer layer at the front of the eyeball. It acts as a window to the eye. The cornea helps to focus light rays onto the retina, this image is then transmitted to the brain. When the cornea is damaged, it can become less transparent or its shape can change. This can prevent light reaching the retina and causes the picture transmitted to the brain to be distorted or unclear. A corneal transplant, also known as keratoplasty or a corneal graft, is an operation to remove all or part of a damaged cornea and replace it with healthy donor tissue. It is used to improve sight, relieve pain and treat severe infection or damage. One of the most common reasons for a cornea transplant is a condition called keratoconus, which causes the cornea to change shape. (NHS.UK) This book is a guide to corneal transplantation (keratoplasty) for ophthalmic surgeons. Divided into seven sections, the text begins with an overview of evolution, preoperative considerations, and eye banking. The following sections cover a multitude of keratoplasty techniques, including endothelial keratoplasty, and their potential complications. The book concludes with discussion on alternatives to corneal transplantation. The third edition of this comprehensive manual has been fully revised, with new topics added, to provide surgeons with the latest advances in the field. A selection of operative videos can be accessed via a QR code provided in the book. The previous edition (9788184488593) published in 2010.

Cornea E-Book

Author : Mark J Mannis,Edward J Holland
Publisher : Elsevier Health Sciences
Page : 2189 pages
File Size : 46,7 Mb
Release : 2016-09-23
Category : Medical
ISBN : 9780323357586

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Cornea E-Book by Mark J Mannis,Edward J Holland Pdf

Highly praised in its first three editions, Cornea has become a market-leading cornerstone text and the immediate go-to resource for anyone working in this hugely popular and evolving sub-specialty. Offered over two volumes and featuring the knowledge of over 200 experts worldwide, it presents state-of-the-art coverage of the expanding range of contemporary corneal surgery, new diagnostic technology, and medical management of corneal and external disease as well as ocular surface disease. This updated edition includes 20 brand-new chapters, while an enhanced focus on images provides key visual guidance in this challenging field. Exceptionally clear illustrations, diagnostic images, and step-by-step surgical photographs offer superb visual guidance. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices. 20 brand-new chapters cover the latest advances in the field, such as DMEK, Ultra-Thin DSEK and DSAEK techniques; endothelial cell transplantation; keratoplasty and prosthokeratoplasty techniques; collagen cross-linking; and new refractive surgical techniques (presbyopic implants and SMILE surgery). 60 video clips on Expert Consult show new footage of the latest corneal surgery techniques, including Boston Keratoprosthesis, corneal inlay surgery, and lenticule extraction. Boasts over 170 chapters with unique, cutting-edge content, as well as 2,300 clear illustrations – 670 of which are new to this edition. Presents a detailed exposition of the growing number of techniques for lamellar keratoplasty, including outcomes. Includes new sections on the latest developments in the management of ocular surface disease. Key point overviews in each chapter offer easier access to crucial information.

Surgical Ophthalmology

Author : F.C. Blodi,Günter Mackensen,Hellmut Neubauer
Publisher : Springer Science & Business Media
Page : 607 pages
File Size : 48,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642753855

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Surgical Ophthalmology by F.C. Blodi,Günter Mackensen,Hellmut Neubauer Pdf

These two volumes of "Surgical Ophthalmology" represent the fruits of a long standing cooperation among a number of experts in the various subspecialties of ophthalmology. The editors have attempted to harmonize the individual contribu tions. The illustrations are of a more or less uniform character and present in di dactic sketches the individual steps of the most important operations. This should be of benefit not only for the neophyte, but also for the expert. The text has in a similary way been integrated so that the whole work, though written by a number of contributors, presents an organic unit and not a patchwork of different parts. In addition, this work is a monument to the spirit of German-American collab oration. The two German editors have since the end of WWII stressed the advan tages of such collaborative efforts. They have established close personal contacts with many American ophthalmologists. They have participated in and contributed to many American congresses, meetings and symposia. The American editor, on the other hand, as a product of the Viennese school, has always stressed the im portant contributions by German-speaking ophthalmologists and the value of the German literature.

Ophthalmology

Author : Bruce James,Anthony Bron,Manoj V. Parulekar
Publisher : John Wiley & Sons
Page : 250 pages
File Size : 51,6 Mb
Release : 2016-11-30
Category : Medical
ISBN : 9781119095903

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Ophthalmology by Bruce James,Anthony Bron,Manoj V. Parulekar Pdf

Highly Commended in Internal medicine in the 2017 BMA Medical Book Awards Highly illustrated, comprehensive, and accessible, Ophthalmology Lecture Notes is the ideal reference and revision guide to common eye problems and their diagnosis and management. Beginning with overviews of anatomy, history taking, and examination, it then covers a range of core ophthalmic conditions, including a new chapter on paediatric ophthalmology. The content has been thoroughly updated and includes: Over 200 diagrams and photographs A range of core clinical cases in chapter 20 demonstrating the clinical context of key conditions Learning objectives and summary of key points in each chapter Ophthalmology Lecture Notes is perfect for developing knowledge for clinical practice or revision in the run-up to examinations, and uses a systematic approach to provide medical students and junior doctors with all the tools they need to manage clinical situations. It is also useful for optometrists in training, helping them develop a sound understanding of clinical ophthalmology.