Advanced Bioactive Inorganic Materials For Bone Regeneration And Drug Delivery
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Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery by Chengtie Wu,Jiang Chang,Yin Xiao Pdf
Bioceramics play an important role in repairing and regenerating defective or damaged bone. Annually, more than 500,000 bone graft procedures are performed in the United States and approximately 2.2 million are conducted worldwide. Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery reviews the latest advances in the fiel
Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery by Chengtie Wu,Jiang Chang,Yin Xiao Pdf
Bioceramics play an important role in repairing and regenerating defective or damaged bone. Annually, more than 500,000 bone graft procedures are performed in the United States and approximately 2.2 million are conducted worldwide. Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery reviews the latest advances in the field of bioceramics. The book summarizes innovative concepts, bioceramic design, and methods for material synthesis and drug delivery. Offering guidance for biomedical engineering researchers and material scientists, the book explores: Novel mesoporous bioactive glasses and silicate-based ceramics for bone regeneration and drug delivery Bioactive silicate ceramics, including their mechanical properties, interaction with bone-forming cells, and in vivo osteogenesis and angiogenesis Silica nanospheres with a core-shell structure and their specific properties for controllable drug delivery The 3D-printing technique to prepare advanced bioceramic scaffolds for bone tissue engineering applications—including the preparation, mechanical strength, and biological properties of 3D-printed porous scaffolds of calcium phosphate cement and silicate bioceramics Biomimetic preparation and controllable crystal growth and biomineralization of bioceramics Inorganic and organic composite materials and their unique biological, electrical, and mechanical properties that enable the design of excellent bone regeneration and gene delivery systems A comprehensive survey of the research progress of bioceramics and their applications in bone repair and regeneration, this volume is designed to enhance study and career development for those in this field and to facilitate further research and opportunities for new solutions.
Biomedical Applications of Mesoporous Ceramics by María Vallet-Regí,Miguel Manzano García,Montserrat Colilla Pdf
Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number of publications. As controlled drug delivery systems are one of the most promising applications for human health care, it is now necessary to set the milestones of this technology, from the very basic to the most advanced. Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering is a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The book provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials and bone tissue engineering, detailing the research and development of these biomedical applications.
Advanced Bioceramics by M. Enamul Hoque,Kheng Lim Goh,Suresh Sagadevan Pdf
Advanced Bioceramics: Properties, Processing, and Applications describes development of bioceramics and biocomposites, which are used in various biomedical applications including bone tissue repair, remodelling and regeneration. It covers the fundamental aspects of materials science and bioengineering, clinical performance in a variety of applications, ISO/ASTM specifications, and opportunities and challenges. Offers a comprehensive view of properties and processing of bioceramics Highlights applications in dentistry, orthopaedic and maxillofacial implants, and regenerative and tissue engineering Covers ISO/ASTM specifications such as processing, clinical applications, recycling/reuse and disposal standards Explores health, environmental and ethical issues With contributions from eminent editors and recognized authors around the world, this book should serve as an important reference for academics, scientists, researchers, students and practitioners in materials science and biomedical engineering. It is to assist in the design of novel, targeted and personalised bioceramic-based solutions to advanced healthcare.
Bioactive Materials for Bone Regeneration by Jiang Chang,Xingdong Zhang,Kerong Dai Pdf
Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments
Nanoengineering of Biomaterials by Sougata Jana,Subrata Jana Pdf
A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.
Octacalcium Phosphate Biomaterials by Gerard Insley,Osamu Suzuki Pdf
Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterials Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration
Advanced Techniques in Bone Regeneration by Alessandro Rozim Zorzi,João Batista de Miranda Pdf
Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.
Advanced Materials Interfaces by Ashutosh Tiwari,Hirak K. Patra,Xuemei Wang Pdf
Advanced Material Interfaces is a state-of-the-art look at innovative methodologies and strategies adopted for interfaces and their applications. The 13 chapters are written by eminent researchers not only elaborate complex interfaces fashioned of solids, liquids, and gases, but also ensures cross-disciplinary mixture and blends of physics, chemistry, materials science, engineering and life sciences. Advanced interfaces operate fundamental roles in essentially all integrated devices. It is therefore of the utmost urgency to focus on how newly-discovered fundamental constituents and interfacial progressions can be materialized and used for precise purposes. Interfaces are associated in wide multiplicity of application spectrum from chemical catalysis to drug functions and the advancement is funnelled by fine-tuning of our fundamental understanding of the interface effects.
Advances in Calcium Phosphate Biomaterials by Besim Ben-Nissan Pdf
Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia
This book describes the history, origin and basic characteristics of bioactive materials. It includes a chapter dedicated to hydroxyapatite mineral, its formation and its bioactive properties. The authors address how cytotoxicity is a determining step for bioactivity. Applications of bioactive materials in the contexts of tissue regeneration, bone regeneration and cancer therapy are also covered. Silicate, metallic and mesoporous glasses are described, as well as the challenges and future prospects of research in this field.
Springer Handbook of Glass by J. David Musgraves,Juejun Hu,Laurent Calvez Pdf
This handbook provides comprehensive treatment of the current state of glass science from the leading experts in the field. Opening with an enlightening contribution on the history of glass, the volume is then divided into eight parts. The first part covers fundamental properties, from the current understanding of the thermodynamics of the amorphous state, kinetics, and linear and nonlinear optical properties through colors, photosensitivity, and chemical durability. The second part provides dedicated chapters on each individual glass type, covering traditional systems like silicates and other oxide systems, as well as novel hybrid amorphous materials and spin glasses. The third part features detailed descriptions of modern characterization techniques for understanding this complex state of matter. The fourth part covers modeling, from first-principles calculations through molecular dynamics simulations, and statistical modeling. The fifth part presents a range of laboratory and industrial glass processing methods. The remaining parts cover a wide and representative range of applications areas from optics and photonics through environment, energy, architecture, and sensing. Written by the leading international experts in the field, the Springer Handbook of Glass represents an invaluable resource for graduate students through academic and industry researchers working in photonics, optoelectronics, materials science, energy, architecture, and more.
Bioceramic Coatings for Medical Implants by Robert B. Heimann,Hans D. Lehmann Pdf
Reflecting the progress in recent years, this book provides in-depth information on the preparation, chemistry, and engineering of bioceramic coatings for medical implants. It is authored by two renowned experts with over 30 years of experience in industry and academia, who know the potentials and pitfalls of the techniques concerned. Following an introduction to the principles of biocompatibility, they present the structures and properties of various bioceramics from alumina to zirconia. The main part of the work focuses on coating technologies, such as chemical vapor deposition, sol-gel deposition and thermal spraying. There then follows a discussion of the major interactions of bioceramics with bone or tissue cells, complemented by an overview of the in-vitro testing methods of the biomineralization properties of bioceramics. The text is rounded off by chapters on the functionalization of bioceramic coatings and a look at future trends. As a result, the authors bring together all aspects of the latest techniques for designing, depositing, testing, and implementing improved and novel bioceramic coating compositions, providing a full yet concise overview for beginners and professionals.
Translating Biomaterials for Bone Graft by Joo L. Ong,Teja Guda Pdf
Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.
Bio-Ceramics with Clinical Applications by Maria Vallet-Regi Pdf
This publication offers a unique approach that links the materials science of bioceramics to clinical needs and applications. Providing a structured account of this highly active area of research, the book reviews the clinical applications in bone tissue engineering, bone regeneration, joint replacement, drug-delivery systems and biomimetism, this book is an ideal resource for materials scientists and engineers, as well as for clinicians. From the contents: Part I Introduction 1. Bioceramics 2. Biomimetics Part II Materials 3. Calcium Phosphate Bioceramics 4. Silica-based Ceramics: Glasses 5. Silica-based Ceramics: Mesoporous Silica 6. Alumina, Zirconia, and Other Non-oxide Inert Bioceramics 7. Carbon-based Materials in Biomedicine Part III Material Shaping 8. Cements 9. Bioceramic Coatings for Medical Implants 10. Scaffold Designing Part IV Research on Future Ceramics 11. Bone Biology and Regeneration 12. Ceramics for Drug Delivery 13. Ceramics for Gene Transfection 14. Ceramic Nanoparticles for Cancer Treatment