Advances In Bioanalytical Methods For Probing Ligand Target Interactions

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Advances in Bioanalytical Methods for Probing Ligand-Target Interactions

Author : Quezia B. Cass,Gabriella Massolini,Enrica Calleri,Carmen Lucia Cardoso
Publisher : Frontiers Media SA
Page : 128 pages
File Size : 46,7 Mb
Release : 2020-07-02
Category : Electronic
ISBN : 9782889638185

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Advances in Bioanalytical Methods for Probing Ligand-Target Interactions by Quezia B. Cass,Gabriella Massolini,Enrica Calleri,Carmen Lucia Cardoso Pdf

Women in Analytical Chemistry

Author : Nicole J. Jaffrezic-Renault,Ottavia Giuffrè,Eugenia Gallardo,Camelia Bala,Quezia B. Cass
Publisher : Frontiers Media SA
Page : 222 pages
File Size : 48,7 Mb
Release : 2022-09-22
Category : Science
ISBN : 9782832500286

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Women in Analytical Chemistry by Nicole J. Jaffrezic-Renault,Ottavia Giuffrè,Eugenia Gallardo,Camelia Bala,Quezia B. Cass Pdf

The protagonism of bioanalytical methods in high-throughput drug discovery

Author : Marcela Cristina De Moraes,Fernando Goncalves De Almeida,Luzineide Wanderley Tinoco
Publisher : Frontiers Media SA
Page : 47 pages
File Size : 46,6 Mb
Release : 2023-06-02
Category : Science
ISBN : 9782832524947

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The protagonism of bioanalytical methods in high-throughput drug discovery by Marcela Cristina De Moraes,Fernando Goncalves De Almeida,Luzineide Wanderley Tinoco Pdf

Advanced Materials and Techniques for Biosensors and Bioanalytical Applications

Author : Pranab Goswami
Publisher : CRC Press
Page : 623 pages
File Size : 44,8 Mb
Release : 2020-11-01
Category : Medical
ISBN : 9781000194739

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Advanced Materials and Techniques for Biosensors and Bioanalytical Applications by Pranab Goswami Pdf

Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.

Advances in Microfluidics

Author : Xiao-Ying Yu
Publisher : BoD – Books on Demand
Page : 424 pages
File Size : 48,9 Mb
Release : 2016-11-23
Category : Science
ISBN : 9789535127857

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Advances in Microfluidics by Xiao-Ying Yu Pdf

Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

Advanced Healthcare Materials

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 49,7 Mb
Release : 2014-05-09
Category : Technology & Engineering
ISBN : 9781118773680

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Advanced Healthcare Materials by Ashutosh Tiwari Pdf

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Hydrogen Sulfide

Author : Michael D. Pluth
Publisher : John Wiley & Sons
Page : 596 pages
File Size : 40,8 Mb
Release : 2022-09-21
Category : Science
ISBN : 9781119799870

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Hydrogen Sulfide by Michael D. Pluth Pdf

HYDROGEN SULFIDE Covers H2S interactions, methods of detection and delivery in biological environments, and a wide range of applications Research on hydrogen sulfide (H2S) spans diverse disciplines including chemistry, biology, and physiology. In recent years, new materials and approaches have been developed to deliver H2S and related reactive sulfur species in various clinical contexts. Although many biological pathways involving H2S are complex, all are governed by fundamental chemical interactions between reactive sulfur species and other molecular entities. Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies provides the foundation required for understanding the fundamental chemical biology of H2S while highlighting the compound’s therapeutic potential and medicinal applications. This book covers key aspects of H2S chemical biology, including the fundamental chemistry of reactive sulfur species; the measurement, detection, and delivery of H2S in biological environments; and the therapeutic and medicinal uses of exogenous H2S delivery in various pharmacologically relevant systems. Throughout the text, editor Michael Pluth and chapter contributors discuss the opportunities and future of the multidisciplinary field. Provides approaches for delivering H2S with relevance to biological and therapeutic applications Describes complex interactions of H2S with bioinorganic complexes and reactive sulfur, nitrogen, and oxygen species Summarizes advances in available tools to detect, measure, and modulate H2S levels in biological environments, such as real-time methods for H2S fluorescence imaging in live cell and animal systems Helps readers understand known systems and make connections to new and undiscovered pathways and mechanisms of action Includes in-depth case studies of different systems in which H2S plays an important role Hydrogen Sulfide: Chemical Biology Basics, Detection Methods, Therapeutic Applications, and Case Studies is an important source of current knowledge for researchers, academics, graduate students, and industrial scientists in the fields of redox biology, hydrogen sulfide research, and medicinal chemistry of small biological molecules.

Index Medicus

Author : Anonim
Publisher : Unknown
Page : 2520 pages
File Size : 51,9 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P00992562I

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Cheminformatics and its Applications

Author : Amalia Stefaniu,Azhar Rasul,Ghulam Hussain
Publisher : BoD – Books on Demand
Page : 192 pages
File Size : 42,7 Mb
Release : 2020-07-15
Category : Medical
ISBN : 9781838800673

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Cheminformatics and its Applications by Amalia Stefaniu,Azhar Rasul,Ghulam Hussain Pdf

Cheminformatics has emerged as an applied branch of Chemistry that involves multidisciplinary knowledge, connecting related fields such as chemistry, computer science, biology, pharmacology, physics, and mathematical statistics.The book is organized in two sections, including multiple aspects related to advances in the development of informatic tools and their specific use in compound structure databases with various applications in life sciences, mainly in medicinal chemistry, for identification and development of new therapeutically active molecules. The book covers aspects related to genomic analysis, semantic similarity, chemometrics, pattern recognition techniques, chemical reactivity prediction, drug-likeness assessment, bioavailability, biological target recognition, machine-based drug discovery and design. Results from various computational tools and methods are discussed in the context of new compound design and development, sharing promising opportunities, and perspectives.

Neurotransmitters in Plants

Author : Akula Ramakrishna,Victoria Vladimirovna Roshchina
Publisher : CRC Press
Page : 456 pages
File Size : 41,5 Mb
Release : 2018-09-03
Category : Science
ISBN : 9781351360418

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Neurotransmitters in Plants by Akula Ramakrishna,Victoria Vladimirovna Roshchina Pdf

Key features: Presents the latest trends and developments of neuromediators in plants Provides in-depth coverage of plants enriched in neurotransmitters (especially serotonin, melatonin, and dopamine) and how they are used in medicine, pharmacy, and food nutrition Discusses the physiological role of the neurotransmitters (biomediators) in non-nervous systems including the analysis of effects on the growth and development and stress defense Covers the occurrence of the substances that act in human and animal nervous system in plants as a phenomenon of the universal irritability feature for biologists Reveals the occurrence and possible physiological functions of biogenic amines in plants, food, and human health New scientific data confirm the origin of neurotransmitters in the ancient ocean, whose inhabitants use the compounds in their relationships. One example is the algae Ulvaria, whose image is represented on the cover. During evolution, plant and microbial cells stored the neurotransmitters that play multifunctional roles today. Researchers have paid special attention to their functions in plants, the oxygen well of our planet. This book provides powerful tools for both analyzing and manipulating organisms, considering the functions of neurotransmitters in plant cells and the practical application of knowledge about acetylcholine, catecholamines, serotonin, melatonin, histamine, gamma-aminobutyric acid and glutamine for ecology, agriculture, medicine and food industries. Neurotransmitters in Plants: Perspectives and Applications presents information on: the location and biosynthesis where neurotransmitters occur the molecular biology of some enzymes participating in the process their role in vivo and in vitro processes their functions in plant environmental adaptation in plants their role in enriching the food and medicinal value of plants.

Recent Developments in Biomolecular NMR

Author : Marius Clore,Jennifer Potts
Publisher : Royal Society of Chemistry
Page : 362 pages
File Size : 54,7 Mb
Release : 2012
Category : Science
ISBN : 9781849731201

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Recent Developments in Biomolecular NMR by Marius Clore,Jennifer Potts Pdf

This text draws together experts in the field to discuss advances in nuclear magnetic resonance methods that have occurred or had an impact on the biomolecular field in the last few years.

Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design

Author : Sanjeev Kumar Singh
Publisher : Springer Nature
Page : 334 pages
File Size : 43,8 Mb
Release : 2021-02-02
Category : Science
ISBN : 9789811589362

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Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design by Sanjeev Kumar Singh Pdf

This book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery and development, as well as in clinical studies. Yet, despite the rapid advances in computer software and hardware, combined with the exponential growth in the available biological information, there are many challenges that still need to be addressed, as this book shows. In turn, it shares valuable insights into receptor-ligand interactions in connection with various biological functions and human diseases. The book discusses a wide range of phylogenetic methods and highlights the applications of Molecular Dynamics Simulation in the drug discovery process. It also explores the application of quantum mechanics in order to provide better accuracy when calculating protein-ligand binding interactions and predicting binding affinities. In closing, the book provides illustrative descriptions of major challenges associated with computer-aided drug discovery for the development of therapeutic drugs. Given its scope, it offers a valuable asset for life sciences researchers, medicinal chemists and bioinformaticians looking for the latest information on computer-aided methodologies for drug development, together with their applications in drug discovery.

Micro and Nano Technologies in Bioanalysis

Author : James W. Lee,Robert S. Foote
Publisher : Humana Press
Page : 0 pages
File Size : 52,5 Mb
Release : 2011-12-01
Category : Science
ISBN : 1617794872

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Micro and Nano Technologies in Bioanalysis by James W. Lee,Robert S. Foote Pdf

In recent years, large-scale advances in technology have led to greater understanding of the world on a much tinier scale: the biomolecular level. In Micro and Nano Technologies in Bioanalysis: Methods and Protocols, expert researchers from across the globe explore the technology which makes this analysis possible, investigating the worlds of microfluidics and nanotechnologies, and examining physical science techniques for the separation, detection, manipulation, and analysis of biomolecules. This volume contains innovative protocols on the application of microfluidics and the utilization of physical science-related technologies that will prove to be invaluable in the field of molecular biology. Chapters contain cutting edge applications of emerging nanotechnologies, including quantum dots and molecular fluorescence for the imaging and tracking of biomolecules. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and groundbreaking, Micro and Nano Technologies in Bioanalysis: Methods and Protocols is a necessary tool for cellular biologists, biochemists, microbiologists, geneticists and medical researchers alike.

Combinatorial Methods for Chemical and Biological Sensors

Author : Radislav A. Potyrailo,Vladimir M. Mirsky
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 51,7 Mb
Release : 2009-03-21
Category : Science
ISBN : 9780387737133

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Combinatorial Methods for Chemical and Biological Sensors by Radislav A. Potyrailo,Vladimir M. Mirsky Pdf

Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.

Handbook of Surface Plasmon Resonance

Author : Richard B. M. Schasfoort
Publisher : Royal Society of Chemistry
Page : 555 pages
File Size : 46,9 Mb
Release : 2017-05-30
Category : Science
ISBN : 9781782627302

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Handbook of Surface Plasmon Resonance by Richard B. M. Schasfoort Pdf

Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.