Advances In Biological Solid State Nmr

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Advances in Biological Solid-State NMR

Frances Separovic,Akira Naito
Advances in Biological Solid State NMR Book PDF

Author : Frances Separovic,Akira Naito
Publisher : Royal Society of Chemistry
Page : 632 pages
File Size : 44,9 Mb
Release : 2014
Category : Science
ISBN : 9781849739108

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Advances in Biological Solid-State NMR by Frances Separovic,Akira Naito Pdf

Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions

Perspectives on Solid State NMR in Biology

S.R. Kiihne,H.J.M. de Groot
Perspectives on Solid State NMR in Biology Book PDF

Author : S.R. Kiihne,H.J.M. de Groot
Publisher : Springer Science & Business Media
Page : 227 pages
File Size : 53,9 Mb
Release : 2013-03-14
Category : Science
ISBN : 9789401725798

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Perspectives on Solid State NMR in Biology by S.R. Kiihne,H.J.M. de Groot Pdf

Solid state NMR is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings -; from a recent international workshop - captures an image of the latest developments and future directions for solid state NMR in biological research, particularly on membrane proteins. Detailed information on how hormones or drugs bind to their membrane receptor targets is needed, e.g. for rational drug design. Higher fields are bringing clear improvements, and the power of solid state NMR techniques for studying amorphous and membrane associated peptides, proteins and complexes is shown by examples of applications at ultra-high fields. Progress in protein expression, experimental design and data analysis are also presented by leaders in these research areas.

NMR Spectroscopy of Biological Solids

A. Ramamoorthy
NMR Spectroscopy of Biological Solids Book PDF

Author : A. Ramamoorthy
Publisher : CRC Press
Page : 368 pages
File Size : 45,6 Mb
Release : 2005-09-22
Category : Science
ISBN : 9781420027617

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NMR Spectroscopy of Biological Solids by A. Ramamoorthy Pdf

Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-forming molecules, and molecules embedded in the cell membrane. Filling a void in the current literature, NMR Spectroscopy of Biological Solids examines all the recent developments, implementation, and interpretation of solid-state NMR experiments and the advantages of applying them to biological systems. The book emphasizes how these techniques can be used to realize the structure of non-crystalline systems of any size. It explains how these isotropic and anisotropic couplings interactions are used to determine atomic-level structures of biological molecules in a non-soluble state and extrapolate the three-dimensional structure of membrane proteins using magic-angle spinning (MAS). The book also focuses on the use of multidimensional solid-state NMR methods in the study of aligned systems to provide basic information about the mechanisms of action of a variety of biologically active molecules. Addressing principles, methods, and applications, this book provides a critical selection of solid-state NMR methods for solving a wide range of practical problems that arise in both academic and industrial research of biomolecules in the solid state. NMR Spectroscopy of Biological Solids is a forward-thinking resource for students and researchers in analytical chemistry, bioengineering, material sciences, and structural genomics.

Current Developments in Solid State NMR Spectroscopy

Norbert Müller,Perunthiruthy K. Madhu
Current Developments in Solid State NMR Spectroscopy Book PDF

Author : Norbert Müller,Perunthiruthy K. Madhu
Publisher : Springer Science & Business Media
Page : 143 pages
File Size : 40,9 Mb
Release : 2013-04-17
Category : Science
ISBN : 9783709137154

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Current Developments in Solid State NMR Spectroscopy by Norbert Müller,Perunthiruthy K. Madhu Pdf

Why to apply solid-state NMR? - By now, we should have learned that NMR is mainly used for the study of molecules in solution, while x-ray diffraction is the method of choice for solids. Based on this fact, the two recent 'NMR-Nobelprizes' went indeed into the liquid phase: my own one eleven years ago, and particularly the most recent one to Kurt Wuthrich. His prize is beyond any doubts very well justified. His contribution towards the study of biomolecules in solution, in their native (or almost native) environment is truly monumental. We all will profit from it indirectly when one of our future diseases will be cured with better drugs, based on the insightful knowledge gained through liquid-state NMR. Two fields of NMR are still left out of the Nobel Prize game: magnetic reso nance imaging (MRI) and solid-state NMR. The disrespect for MRI in Stockholm is particularly difficult to understand; but this is not a subject to be discussed at the present place. Solid-state NMR is the third of the three great fields of NMR, powerful already today and very promising for the near future.

Solid-state NMR

Frances Separovic,Marc-Antoine Sani
Solid state NMR Book PDF

Author : Frances Separovic,Marc-Antoine Sani
Publisher : Unknown
Page : 0 pages
File Size : 49,7 Mb
Release : 2020
Category : Membranes (Biology)
ISBN : 0750325321

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Solid-state NMR by Frances Separovic,Marc-Antoine Sani Pdf

The purpose of this book is to describe the methodology and applications of solid-state NMR spectroscopy to studies of membrane proteins, membrane-active peptides and model biological membranes. As well as structural studies, this book contains coverage of membrane interactions and molecular motions. Advances in biological solid-state NMR are very pertinent with high-field developments seeing applications in biological membranes and whole cells. Experts who are leaders in the development and application of biological solid-state NMR are chapter contributors. Part of Biophysical Society-IOP series.

Advances in Biological Solid-State NMR

Frances Separovic,Akira Naito
Advances in Biological Solid State NMR Book PDF

Author : Frances Separovic,Akira Naito
Publisher : Royal Society of Chemistry
Page : 128 pages
File Size : 42,5 Mb
Release : 2014-03-17
Category : Science
ISBN : 9781782621195

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Advances in Biological Solid-State NMR by Frances Separovic,Akira Naito Pdf

The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation. Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis. Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which is essential reading for those working or studying at postgraduate level in this exciting field.

Modern Methods in Solid-state NMR

Paul Hodgkinson
Modern Methods in Solid state NMR Book PDF

Author : Paul Hodgkinson
Publisher : Royal Society of Chemistry
Page : 452 pages
File Size : 54,7 Mb
Release : 2018-04-05
Category : Science
ISBN : 9781788014199

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Modern Methods in Solid-state NMR by Paul Hodgkinson Pdf

Solid-state NMR covers an enormous range of material types and experimental techniques. Although the basic instrumentation and techniques of solids NMR are readily accessible, there can be significant barriers, even for existing experts, to exploring the bewildering array of more sophisticated techniques. In this unique volume, a range of experts in different areas of modern solid-state NMR explain about their area of expertise, emphasising the “practical aspects” of implementing different techniques, and illustrating what questions can and cannot be addressed. Later chapters address complex materials, showing how different NMR techniques discussed in earlier chapters can be brought together to characterise important materials types. The volume as a whole focusses on topics relevant to the developing field of “NMR crystallography” – the use of solids NMR as a complement to diffraction crystallography. This book is an ideal complement to existing introductory texts and reviews on solid-state NMR. New researchers wanting to understand new areas of solid-state NMR will find each chapter to be the equivalent to spending time in the laboratory of an internationally leading expert, learning the hints and tips that make the difference between knowing about a technique and being ready to put it into action. With no equivalent on the market, it will be of interest to every solid-state NMR researcher (academic and postgraduate) working in the chemical sciences.

Biomolecular NMR Spectroscopy

Andrew J. Dingley,A. J. Dingley,Steven M. Pascal
Biomolecular NMR Spectroscopy Book PDF

Author : Andrew J. Dingley,A. J. Dingley,Steven M. Pascal
Publisher : IOS Press
Page : 488 pages
File Size : 42,7 Mb
Release : 2011
Category : Medical
ISBN : 9781607506942

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Biomolecular NMR Spectroscopy by Andrew J. Dingley,A. J. Dingley,Steven M. Pascal Pdf

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--

Recent Developments in Biomolecular NMR

Marius Clore,Jennifer Potts
Recent Developments in Biomolecular NMR Book PDF

Author : Marius Clore,Jennifer Potts
Publisher : Royal Society of Chemistry
Page : 250 pages
File Size : 46,5 Mb
Release : 2012-08-21
Category : Science
ISBN : 9781849735391

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Recent Developments in Biomolecular NMR by Marius Clore,Jennifer Potts Pdf

NMR spectroscopy is widely used in biomolecular science particularly for structure determination of proteins, nucleic acids and carbohydrates. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an important technique in structural biology. Filling a gap in the literature, this book draws together experts in the field to discuss the real advances in NMR methods that have occurred or have an impact on the biomolecular field in the last few years. The coverage includes recent developments in using NMR for determination of protein structures, membrane proteins, the dynamics of RNA and advances in NMR in drug discovery. Edited by leading biological NMR spectroscopists, the book is essential reference for researchers in industry and academia interested in or joining this bioanalytical field.

Solid State NMR Studies of Biopolymers

Anne E. McDermott,Tatyana Polenova
Solid State NMR Studies of Biopolymers Book PDF

Author : Anne E. McDermott,Tatyana Polenova
Publisher : John Wiley & Sons
Page : 596 pages
File Size : 49,8 Mb
Release : 2012-12-19
Category : Science
ISBN : 9781118588888

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Solid State NMR Studies of Biopolymers by Anne E. McDermott,Tatyana Polenova Pdf

The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here

NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces

Anirban Bhunia,Hanudatta S Atreya,Neeraj Sinha
NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces Book PDF

Author : Anirban Bhunia,Hanudatta S Atreya,Neeraj Sinha
Publisher : Royal Society of Chemistry
Page : 733 pages
File Size : 49,9 Mb
Release : 2022-08-17
Category : Science
ISBN : 9781839162091

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NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces by Anirban Bhunia,Hanudatta S Atreya,Neeraj Sinha Pdf

Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies.

Nuclear Magnetic Resonance Volume 47

Paul Hodgkinson
Nuclear Magnetic Resonance Volume 47 Book PDF

Author : Paul Hodgkinson
Publisher : Royal Society of Chemistry
Page : 299 pages
File Size : 48,5 Mb
Release : 2021-11-29
Category : Science
ISBN : 9781839163913

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Nuclear Magnetic Resonance Volume 47 by Paul Hodgkinson Pdf

Applications of nuclear magnetic resonance span a wide range of scientific disciplines, from physics to medicine. For those wanting to become acquainted with NMR or seasoned practitioners, this is a valuable source of current methods and applications.

Solid-State NMR IV Methods and Applications of Solid-State NMR

B. Blümich
Solid State NMR IV Methods and Applications of Solid State NMR Book PDF

Author : B. Blümich
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642791277

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Solid-State NMR IV Methods and Applications of Solid-State NMR by B. Blümich Pdf

Solid-State NMR is a branch of Nuclear Magnetic Resonance which is presently experiencing a phase of strongly increasing popularity. The most striking evidence is the large number of contributions from Solid-State Resonance at NMR meetings, approaching that ofliquid state resonance. Important progress can be observed in the areas of methodological developments and applications to organic and inorganic matter. One volume devoted to more or less one of each of these areas has been published in the preceding three issues. This volume can be considered an addendum to this series. Selected methods and applications of Solid-State NMR are featured in three chapters. The first one treats the recoupling of dipolar interactions in solids, which are averaged by fast sample rotation. Following an introduction to effective Hamiltonians and Floquet theory, different types of experiment such as rotary resonance, dipolar chemical shift correlation spectroscopy, rotational resonance and multipulse recoupling are treated in the powerful Floquet formalism. In the second chapter, the different approaches to line narrowing of quadrupolar nuclei are reviewed in a. consistent formulation of double resonance (DaR) and dynamic angle spinning (DAS). Practical aspects of probe design are considered as well as advanced 2D experiments, sensitivity enhancement techniques, and spinning sideband manipulations. The use of such techniques dramatically increases the number of nuclei which can be probed in high resolution NMR spectroscopy. The final chapter describes new experimental approaches and results of structural studies of noncrystalline solids.

Biological NMR

Anonim
Biological NMR Book PDF

Author : Anonim
Publisher : Academic Press
Page : 544 pages
File Size : 54,8 Mb
Release : 2019-01-10
Category : Science
ISBN : 9780128167632

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Biological NMR by Anonim Pdf

Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs & micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery, Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration, Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, and much more. Authoritative contributors Protocols for state-of-the-art advances Timeliness

Modern Techniques in Protein NMR

N. Rama Krishna,Lawrence J. Berliner
Modern Techniques in Protein NMR Book PDF

Author : N. Rama Krishna,Lawrence J. Berliner
Publisher : Springer Science & Business Media
Page : 387 pages
File Size : 49,9 Mb
Release : 2006-04-11
Category : Medical
ISBN : 9780306470837

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Modern Techniques in Protein NMR by N. Rama Krishna,Lawrence J. Berliner Pdf

Volume 16 marks the beginning of a special topic series devoted to modern techniques in protein NMR, under the Biological Magnetic Resonance series. This volume is being followed by Volume 17 with the subtitle Structure Computation and Dynamics in Protein NMR. Volumes 16 and 17 present some of the recent, significant advances in biomolecular NMR field with emphasis on developments during the last five years. We are honored to have brought together in these volumes some of the world’s foremost experts who have provided broad leadership in advancing this field. Volume 16 contains advances in two broad categories: the first, Large Proteins, Complexes, and Membrane Proteins, and second, Pulse Methods. Volume 17, which will follow covers major advances in Computational Methods, and Structure and Dynamics. In the opening chapter of Volume 16, Marius Clore and Angela Gronenborn give a brief review of NMR strategies including the use of long range restraints in the structure determination of large proteins and protein complexes. In the next two chapters, Lewis Kay and Ron Venters and their collaborators describe state-of-t- art advances in the study of perdeuterated large proteins. They are followed by Stanley Opella and co-workers who present recent developments in the study of membrane proteins. (A related topic dealing with magnetic field induced residual dipolar couplings in proteins will appear in the section on Structure and Dynamics in Volume 17).