Advances In Regenerative Medicine Role Of Nanotechnology And Engineering Principles

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Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles

Venkatram Prasad Shastri,George Altankov,Andreas Lendlein
Advances in Regenerative Medicine Role of Nanotechnology and Engineering Principles Book PDF

Author : Venkatram Prasad Shastri,George Altankov,Andreas Lendlein
Publisher : Springer Science & Business Media
Page : 414 pages
File Size : 46,6 Mb
Release : 2010-08-14
Category : Technology & Engineering
ISBN : 9789048187881

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Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles by Venkatram Prasad Shastri,George Altankov,Andreas Lendlein Pdf

This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.

Micro and Nanotechnologies in Engineering Stem Cells and Tissues

Murugan Ramalingam,Esmaiel Jabbari,Seeram Ramakrishna,Ali Khademhosseini
Micro and Nanotechnologies in Engineering Stem Cells and Tissues Book PDF

Author : Murugan Ramalingam,Esmaiel Jabbari,Seeram Ramakrishna,Ali Khademhosseini
Publisher : John Wiley & Sons
Page : 394 pages
File Size : 51,9 Mb
Release : 2013-05-10
Category : Science
ISBN : 9781118574805

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Micro and Nanotechnologies in Engineering Stem Cells and Tissues by Murugan Ramalingam,Esmaiel Jabbari,Seeram Ramakrishna,Ali Khademhosseini Pdf

A cutting-edge look at the application of micro and nanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine. Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growth Various engineering approaches for stem cell, vascular tissue, and bone regeneration The design and processing of biocompatible polymers and other biomaterials Characterization of the interactions between cells and biomaterials Unrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.

Nanotechnology in Regenerative Medicine

Melba Navarro,Josep A. Planell
Nanotechnology in Regenerative Medicine Book PDF

Author : Melba Navarro,Josep A. Planell
Publisher : Humana Press
Page : 319 pages
File Size : 55,6 Mb
Release : 2011-11-01
Category : Science
ISBN : 1617793892

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Nanotechnology in Regenerative Medicine by Melba Navarro,Josep A. Planell Pdf

Nanotechnology plays a key leading role in developing tools able to identify, measure, and study cellular events at the nanometric level as well as in contributing to the disclosure of unknown biological interactions and mechanisms, which opens the door for advances including nanodevices for diagnostic and therapy, drug delivery systems, and regenerative medicine. In Nanotechnology in Regenerative Medicine: Methods and Protocols, expert researchers in the field provide an overview of a very wide range of currently used technologies and methods that involve nanotechnology principles applicable to tissue regeneration. Being that the application of nanotechnology to regenerative medicine is a very broad field, this book focuses its interests on particular areas such as its use as a means to produce efficient platforms and structures for tissue engineering, delivery systems and biosensors, as well as the use of some techniques to study materials surfaces and the interactions between cells, biomolecules, and surfaces at the nanoscale. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their related topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Nanotechnology in Regenerative Medicine: Methods and Protocols provides established scientists, junior researchers, and students involved in the bioengineering, biotechnology, and biomedical fields with a sound foundation in a variety of vital nanotechnology approaches in regenerative medicine.

Principles of Regenerative Medicine

Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Principles of Regenerative Medicine Book PDF

Author : Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Publisher : Academic Press
Page : 1454 pages
File Size : 49,9 Mb
Release : 2018-08-09
Category : Medical
ISBN : 9780128098936

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Principles of Regenerative Medicine by Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem Pdf

Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine

Regenerative Medicine - from Protocol to Patient

Gustav Steinhoff
Regenerative Medicine from Protocol to Patient Book PDF

Author : Gustav Steinhoff
Publisher : Springer
Page : 244 pages
File Size : 54,9 Mb
Release : 2016-04-12
Category : Science
ISBN : 9783319282749

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Regenerative Medicine - from Protocol to Patient by Gustav Steinhoff Pdf

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. The collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 3: Tissue engineering, Biomaterials and Nanotechnology focuses the development of technologies, which enable an efficient transfer of therapeutic genes and drugs exclusively to target cells and potential bioactive materials for clinical use. Principles of tissue engineering, vector technology, multifunctionalized nanoparticles, biodegradable materials, controlled release, and biointerface technology are described with regard to the development of new clinical cell technology. Imaging and targeting technologies as well as biological aspects of tissue and organ engineering are depicted.

Nanoengineered Biomaterials for Regenerative Medicine

Masoud Mozafari,Jayakumar Rajadas,David Kaplan
Nanoengineered Biomaterials for Regenerative Medicine Book PDF

Author : Masoud Mozafari,Jayakumar Rajadas,David Kaplan
Publisher : Elsevier
Page : 516 pages
File Size : 45,5 Mb
Release : 2018-09-17
Category : Science
ISBN : 9780128133569

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Nanoengineered Biomaterials for Regenerative Medicine by Masoud Mozafari,Jayakumar Rajadas,David Kaplan Pdf

Nanoengineered Biomaterials for Regenerative Medicine showcases the advances that have taken place in recent years as an increasing number of nanoengineered biomaterials have been targeted to various organ tissues. The book systematically explores how nanoengineered biomaterials are used in different aspects of regenerative medicine, including bone regeneration, brain tissue reconstruction and kidney repair. It is a valuable reference resource for scientists working in biomaterials science who want to learn more about how nanoengineered materials are practically applied in regenerative medicine. Nanoengineered biomaterials have gained particular focus due to their many advantages over conventional techniques for tissue repair. As a wide range of biomaterials and nanotechnology techniques have been examined for the regeneration of tissues, this book highlights the discussions and advancements made. Provides a digestible reference source for surgeons and physicians who want to learn more on nanoengineered biomaterials and their use in effective medical treatments Offers systematic coverage on how nanoengineered biomaterials are used for different types of medicine Assesses the benefits and drawbacks of the use of bioengineered nanomaterials in different areas of regenerative medicine

Principles of Regenerative Medicine

Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Principles of Regenerative Medicine Book PDF

Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publisher : Academic Press
Page : 1202 pages
File Size : 54,9 Mb
Release : 2010-12-16
Category : Science
ISBN : 0123814235

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Principles of Regenerative Medicine by Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem Pdf

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Nanotechnology and Regenerative Medicine

Maria H. Santana,Eliana B. Souto,Ranjita Shegokar
Nanotechnology and Regenerative Medicine Book PDF

Author : Maria H. Santana,Eliana B. Souto,Ranjita Shegokar
Publisher : Academic Press
Page : 615 pages
File Size : 48,8 Mb
Release : 2022-11-24
Category : Science
ISBN : 9780323904322

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Nanotechnology and Regenerative Medicine by Maria H. Santana,Eliana B. Souto,Ranjita Shegokar Pdf

"Cell niches are present in several human body tissues as a dynamic microenvironment essential to modulate stem cells’ behavior in health, under injury, and in regenerative processes. The interplay between stem cells and their niche is necessary for sustaining tissues. The extracellular matrix (ECM) is the crucial component of the stem cell. It defines the architectural space, physical binding to the cell membrane, and interactions with the neighborhood cells and supports physical stress. Domains with nano or micrometric sizes define the surface and topology of the ECM, mediating cell interactions and macrophage recruitment to injured sites. Over the last two decades, the integration of biomedicine with other engineering and biomaterial sciences promoted the development of nanotechnology and regenerative medicine toward mimicking the specialized stem cell niches to treat diseases with less invasive and efficient therapies. Innovative approaches in nanotechnology, such as targeting the immunological system, transporting drugs across blood–brain/BBB and blood–retinal barriers/BRB, directing active moiety to specific disease location/organs, encapsulation of multiple components, and promoting signalization and pathway-specific surfaces for cell interactions and growth, are indeed promising. On the other side, developments of biomaterial scaffolds to mimic the cell niches for interactions with stem cells in vitro or in vivo have tremendous potential. The three-dimensional printing technology offers a base for a wide array of applications, for example, developing tissue constructs, mimetic organs, organoids, and organ-on-a-chip, thus avoiding the differences between animal model species and humans. Aiming closer to the natural environments, fresh autologous products from the blood, such as platelet-rich plasma (PRP), contain platelets and leukocytes, providing growth factors, cytokines, and proteins for the resident stem cells in the stages of regeneration. PRP also provides pain relief, reducing disabilities in elderly or diseased people. This book brings thought-provoking multidisciplinary topics on the diverse aspects of basic and applied sciences. The prime focus of the compilation is to understand the challenges researchers encounter in combining nanotechnology and regenerative medicine, ultimately integrating both disciplines for the benefit of the patient and offering them a ray of hope to be cured. Presents multi-disciplined knowledge on bench-to-bedside application of nanotechnology in regenerative medicines Highlights the fundamentals, frontiers, limitations, and challenges faced by regenerative medicines Exhibits synergy of biotechnology, nanomedicine, biomedicine, chemical-material engineering, pharmaceutical technology, and applied medical sciences in success of regenerative medicines

Tissue and Organ Regeneration

Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster
Tissue and Organ Regeneration Book PDF

Author : Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster
Publisher : CRC Press
Page : 822 pages
File Size : 55,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9789814411684

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Tissue and Organ Regeneration by Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster Pdf

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell–based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues. This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.

Tissue Engineering and Regenerative Medicine

Murugan Ramalingam,Pekka Vallittu,Ugo Ripamonti,Wan-Ju Li
Tissue Engineering and Regenerative Medicine Book PDF

Author : Murugan Ramalingam,Pekka Vallittu,Ugo Ripamonti,Wan-Ju Li
Publisher : CRC Press
Page : 595 pages
File Size : 50,5 Mb
Release : 2012-09-18
Category : Medical
ISBN : 9781439881859

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Tissue Engineering and Regenerative Medicine by Murugan Ramalingam,Pekka Vallittu,Ugo Ripamonti,Wan-Ju Li Pdf

Through the integration of strategies from life science, engineering, and clinical medicine, tissue engineering and regenerative medicine hold the promise of new solutions to current health challenges. This rapidly developing field requires continual updates to the state-of-the-art knowledge in all of the aforementioned sciences. Tissue Engineering and Regenerative Medicine: A Nano Approach provides a compilation of the important aspects of tissue engineering and regenerative medicine, including dentistry, from fundamental principles to current advances and future trends. Written by internationally renowned scientists, engineers, and clinicians, the chapters cover the following areas: Nanobiomaterials and scaffolds—including nanocomposites and electrospun nanofibers Tissue mechanics Stem cells and nanobiomaterials Oral and cranial implants and regeneration of bone Cartilage tissue engineering Controlled release—DNA, RNA, and protein delivery Animal science and clinical medicine The editors designed this textbook with a distinctive theme focusing on the utilization of nanotechnology, biomaterials science in tissue engineering, and regenerative medicine with the inclusion of important clinical aspects. In addition to injured veterans and other individuals, increased life expectancy in the industrialized world is creating a growing population that will require regenerative medicine, producing greater pressure to develop procedures and treatments to improve quality of life. This book bridges the gap between nanotechnology and tissue engineering and regenerative medicine, facilitating the merger of these two fields and the important transition from laboratory discoveries to clinical applications.

Nanotechnologies in Preventive and Regenerative Medicine

Vuk Uskokovic
Nanotechnologies in Preventive and Regenerative Medicine Book PDF

Author : Vuk Uskokovic
Publisher : Elsevier
Page : 616 pages
File Size : 41,5 Mb
Release : 2017-11-22
Category : Medical
ISBN : 9780323480642

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Nanotechnologies in Preventive and Regenerative Medicine by Vuk Uskokovic Pdf

Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Tissue Engineering

John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson
Tissue Engineering Book PDF

Author : John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Page : 801 pages
File Size : 51,7 Mb
Release : 2012-12-11
Category : Medical
ISBN : 9781439874004

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Tissue Engineering by John P. Fisher,Antonios G. Mikos,Joseph D. Bronzino,Donald R. Peterson Pdf

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

Bioinspired Biomaterials

Heung Jae Chun,Rui L. Reis,Antonella Motta,Gilson Khang
Bioinspired Biomaterials Book PDF

Author : Heung Jae Chun,Rui L. Reis,Antonella Motta,Gilson Khang
Publisher : Springer Nature
Page : 231 pages
File Size : 53,9 Mb
Release : 2020-06-29
Category : Medical
ISBN : 9789811532580

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Bioinspired Biomaterials by Heung Jae Chun,Rui L. Reis,Antonella Motta,Gilson Khang Pdf

This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. Topics addressed in this volume, which is devoted to bioinspired biomaterials, range from novel biomaterials for regenerative medicine through to emerging enabling technologies with applications in, for example, drug delivery, maternal–fetal medicine, peripheral nerve repair and regeneration, and brain tumor therapy. New bioinspired hydrogels receive detailed attention in the book, and a further focus is the use of bioinspired biomaterials in the regulation of stem cell fate. Here the coverage includes the role of scaffolds in cartilage regeneration, the bioapplication of inorganic nanomaterials in tissue engineering, and guidance of cell migration to improve tissue regeneration. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.

Nanotechnology in Tissue Engineering and Regenerative Medicine

Ketul Popat
Nanotechnology in Tissue Engineering and Regenerative Medicine Book PDF

Author : Ketul Popat
Publisher : CRC Press
Page : 302 pages
File Size : 50,6 Mb
Release : 2010-11-22
Category : Mathematics
ISBN : 1439801428

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Nanotechnology in Tissue Engineering and Regenerative Medicine by Ketul Popat Pdf

Although nanotechnology applied to medicine has a potentially huge impact on drug delivery and tissue engineering, significant challenges need to be resolved before clinically viable nanomedicine or nanobiomedicine therapies will be available. Skillfully edited, with contributions from an expert panel of researchers, Nanotechnology in Tissue Engineering and Regenerative Medicine discusses the use of nanotechnology for medical applications with a focus on its use for drug delivery and tissue engineering. It sheds light on the challenges facing the field and examines cutting-edge research that may provide solutions. Topics covered include: Patterning of biomimetic substrates with AFM lithography, primarily focusing on DPN Nanotemplating polymer melts Nanotechnology-based approaches in the treatment of injuries to tendons and ligaments Progress in the use of electrospinning processing techniques for fabricating nanofiber scaffolds for neural applications Nanotopography techniques for tissue-engineered scaffolds and the effects of nanotopography on cells and tissues Vertically aligned TiO2 nanotube surface structuring for optimization of Ti implants utilizing nanotechnology Applications originating from the harmony of nanotechnology to biological systems, especially for the regeneration in the nervous system Current understanding of the mechanisms by which cells sense nano-scale structure at the molecular level and how this understanding can be useful in developing novel antifouling materials While there are books available on tissue engineering and nanotechnology and others about regenerative medicine, most do not comprehensively cover applications of nanotechnology to both these areas. Focusing chiefly on drug delivery, tissue engineering, and regenerative medicine, the book uses an application-based approach to relate laboratory-based research to the development of technologies that can be readily adaptable to an industrial environment.

Foundations of Regenerative Medicine

Anthony Atala
Foundations of Regenerative Medicine Book PDF

Author : Anthony Atala
Publisher : Academic Press
Page : 824 pages
File Size : 43,6 Mb
Release : 2009-09-04
Category : Science
ISBN : 0123785626

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Foundations of Regenerative Medicine by Anthony Atala Pdf

The interdisciplinary field of regenerative medicine holds the promise of repairing and replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Derived from the fields of tissue engineering, cell and developmental biology, biomaterials science, nanotechnology, physics, chemistry, physiology, molecular biology, biochemistry, bioengineering, and surgery, regenerative medicine is one of the most influential topics of biological research today. Derived from the successful Principles of Regenerative Medicine, this volume brings together the latest information on the advances in technology and medicine and the replacement of tissues and organs damaged by disease. Chapters focus on the fundamental principles of regenerative therapies that have crossover with a broad range of disciplines. From the molecular basis to therapeutic applications, this volume is an essential source for students, researchers, and technicians in tissue engineering, stem cells, nuclear transfer (therapeutic cloning), cell, tissue, and organ transplantation, nanotechnology, bioengineering, and medicine to gain a comprehensive understanding of the nature and prospects for this important field. Highlights the fundamentals of regenerative medicine to relate to a variety of related science and technology fields Introductory chapter directly addresses why regenerative medicine is important to a variety of researchers by providing practical examples and references to primary literature Includes new discoveries from leading researchers on restoration of diseased tissues and organs