Advances In Research On Neurodegeneration

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Advances in Research on Neurodegeneration

Author : P. Riederer,D.B. Calne,R. Horowski,Y. Mizuno,W. Poewe,M.B.H. Youdim
Publisher : Springer Science & Business Media
Page : 215 pages
File Size : 44,5 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9783709168424

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Advances in Research on Neurodegeneration by P. Riederer,D.B. Calne,R. Horowski,Y. Mizuno,W. Poewe,M.B.H. Youdim Pdf

Volume 5 of the series "Advances in Research on Neurodegeneration" is concerned with themes which are currently the focus of intensive research, and in which advances in our understanding of the pathological mechanisms un derlying neurodegenerative diseases are expected in the near future. The first section contains five reviews devoted to the various neuroimaging technolo gies. The discussion is concerned with the question of whether neuroimaging techniques make it possible to follow the process of degeneration as it occurs, and which methods offer the required sensitivity and quantifiability for this purpose. However, the question needs to be examined of whether, given the physical and chemical limitations of these techniques, even under optimal conditions, anatomical resolution can be improved to the extent that neuro degenerative diseases can be diagnosed earlier than currently possible and a confident diagnosis made. The possibilities of using neuroimaging techniques to provide information regarding the effects of neuroprotective or neuroregen erative therapeutic strategies, and for correlating the results of neuropsycho logical research with imaging data are also discussed. The second section is concerned with the significance of endogenous or exogenous neurotoxins as triggers for neurodegenerative processes that may lead to Parkinsonism. Vulnerability factors, which include such factors as nerve ending sensitivity, the synergistic effects of drugs and the various mechanisms underlying different toxins are discussed.

Advances in Research on Neurodegeneration

Author : Y. Mizuno,D.B. Calne,R. Horowski,W. Poewe,P. Riederer,M.B.H. Youdim
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 54,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709162842

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Advances in Research on Neurodegeneration by Y. Mizuno,D.B. Calne,R. Horowski,W. Poewe,P. Riederer,M.B.H. Youdim Pdf

We organized the Seventh International Winter Conference on Neurodegeneration and Neuroinflammation in a small town of Karuizawa in Nagano Prefecture in Japan on January 20 to 22, 1999. Karuizawa is a nice summer as well as winter resort close to the place for winter Olympic game in the year of 1998. Over 40 scientists gathered together and made hot discussion. Neurodegeneration and neuroinflammation are two major and important neurologic disorders, in which satisfactory neuroprotective and neurorestorative treatment is not available yet. For this purpose, understanding of molecular mechanisms of neuronal cell death in these two disorders is imperative. Recently, pathologic processes common to these two groups of disorders have been identified such as the involvement of inflammatory changes, microglia, cytokines, and apoptosis. We intended to involve scientists working in these two major fields together to participate in hot and fruitful discussion for the understanding of neuronal death and for developing newer methods of treatment. The science is progressing so rapidly today and we are working in a very narrow specialized area. Sometimes, we are ignorant about important discoveries in other fields. This conference was a nice opportunity for scien tists working different areas to meet together and to exchange their experi ence. This volume is the proceedings of this Winter Conference.

Advances in Research on Neurodegeneration

Author : R. Horowski,Y. Mizuno,C.W. Olanow,W. Poewe,P. Riederer,J.A. Stoessel,M.B.H. Youdim
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 52,7 Mb
Release : 2013-04-09
Category : Medical
ISBN : 9783709106433

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Advances in Research on Neurodegeneration by R. Horowski,Y. Mizuno,C.W. Olanow,W. Poewe,P. Riederer,J.A. Stoessel,M.B.H. Youdim Pdf

The 10th International Winter Conference on Neurodegeneration (lWCN) has taken place from February 14-16,2002, at the lovely "SchloB Ziethen", an old prussian manor (in Prussia, 'faute de mieux', called 'SchloB', i. e. cas tle or residence). This place is 20 km off Tegel Airport, Berlin's main airport, and has been beautifully restored by baroness Edith von Thiingen (nee von BUlow, i. e. of historical Prussian aristocracy); it lends itself rather perfectly for the IWCN type of small interdisciplinary workshops on neurodegenera tion which combine short lectures with plenty of discussion. In this context, we could quote Alexander von Humboldt's famous opening words for one of the first international scientific meetings held at Berlin, on September 18, 1828: "The main purpose ... does not consist in a mutual reading of manuscripts all to be printed after at least one year in specialised publications, but in the personal communication amongst those who work in similar scientific fields; the oral and thus more stimulating exchange of ideas, might they represent facts, opinions or doubts; the foundation of friendly relations which convey illumination to our sciences, serene grace to our lives and tolerance and mildness to our habits ... Berlin, Sept. 18, 1828 Alexander von Humboldt To the IWCN aficionado, it may come as a little surprise that this is the pub lication of the 10th Winter Conference as this might mean that they must have missed number 9.

Recent Advances in Neurodegeneration

Author : Antonella Borreca
Publisher : BoD – Books on Demand
Page : 102 pages
File Size : 55,8 Mb
Release : 2019-10-09
Category : Medical
ISBN : 9781838812331

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Recent Advances in Neurodegeneration by Antonella Borreca Pdf

This Edited Volume Recent Advances in Neurodegeneration is a is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of neurodegeneration. The book comprises single chapters authored by various researchers and edited by an expert active in the neurodegeneration research area. All chapters are complete in itself but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on neurodegeneration, and open new possible research paths for further novel developments.

Advances in Research on Neurodegeneration

Author : Y. Mizuno,M.B.H. Youdim,D.B. Calne,R. Horowski,W. Poewe,P. Riederer
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 47,8 Mb
Release : 2013-03-07
Category : Medical
ISBN : 9783709168448

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Advances in Research on Neurodegeneration by Y. Mizuno,M.B.H. Youdim,D.B. Calne,R. Horowski,W. Poewe,P. Riederer Pdf

Neurodegeneration is one of the most important subjects of the investigation now and in the coming 21st century. Alzheimer's disease is the leading cause of dementia in the elderly people and Parkinson's disease is one of the major neurologic disorders with the prevalence between 1 and 2/1 000 population in advanced countries. Many others are suffering from intractable neurodegener ative disorders such as amyotrophic lateral sclerosis, Huntington's disease, or spinocerebellar degeneration. No truly effective treatment is available for any of these neurodegenerative disorders except for Parkinson's disease; even in Parkinson's disease, still it is impossible to slow down the disease process with the currently available treatment. It is urgently needed to develop new effective technique to halt or slow down the disease process in each of those disorders. Recent advance in the molecular biological and molecular genetic technique has brought us great progress in the understanding of etiology and pathogenesis of these disorders, but still it is not known how neurons are going to die in these disorders. To explore the question, mutual cooperation and exchange of ideas between basic scientists and clinical peoples are of utmost importance.

Advances in Research on Neurodegeneration

Author : P. Riederer,D.B. Calne,R. Horowski,Y. Mizuno,C.W. Olanow,W. Poewe,M.B.H. Youdim
Publisher : Springer Science & Business Media
Page : 421 pages
File Size : 48,7 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9783709163016

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Advances in Research on Neurodegeneration by P. Riederer,D.B. Calne,R. Horowski,Y. Mizuno,C.W. Olanow,W. Poewe,M.B.H. Youdim Pdf

The 8th International Winter Conference on Neurodegeneration from Febru ary 9 to 13, 2000 took place in Tegernsee, Bavaria, Germany. The interest shown in this symposium, which was carried by invited speakers only, was striking. 28 lectures in 5 sessions dealt with themes on basic science and therapy strategies for neurodegenerative illness. This time especially basic mechanism of cell death and resulting causal treatment possibilities were centre themes of the lectures and lively discussions. In accordance with tradi tion 5 lectures on Multiple Sclerosis finished the convention. 60 scientists from 13 countries discussed current questions to these themes. The Symposium started with a lecture on the history of the develop ment of modern-L-DOPA-therapy. Lectures on cell death of dopaminergic nerve cells, new valuation regarding assembly, built up and function of neuromelanin of Substantia nigra and with this, the question of the physio logic and pathobiochemical role of dopamine and neuromelanin built the first block of themes which consequently extended to molecular and genetic aspects of cell death. Highlights of the symposium were neuroprotective and neuroregenerative future therapy strategies together with discussions on the difficulties of clinical neuroprotection. Developmental biological aspects on nerve cells, reorganisation and neurodegeneration showed a stimulating point of view of momentary and future development possibilities of new and more causal forms of therapy of neurodegenerative illness.

Advances in Research on Neurodegeneration

Author : Werner Poewe,Gerhard Ransmayr
Publisher : Springer Science & Business Media
Page : 170 pages
File Size : 40,7 Mb
Release : 1999-04-15
Category : Medical
ISBN : 3211832629

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Advances in Research on Neurodegeneration by Werner Poewe,Gerhard Ransmayr Pdf

The book contains original articles and reviews presented at the 6th International Winter Conference on Neurodegeneration, held from November 20a "23, 1997 in KitzbA1/4hel/Austria. The aim of this conference was to present and discuss recent data on the interface between neuroimmunology and neurodegeneration, in particular susceptibility to autoimmune and neurodegenerative processes, neuroprotection and restorative treatment strategies. These issues were discussed in the light of recent developments in multiple sclerosis, Parkinsona (TM)s disease, amyotrophic lateral sclerosis, Huntingtona (TM)s disease and multisystem atrophy. The articles highlight topics, which are particularly interesting for the clinician and the neuroscientist. Some of the neuroprotective strategies have already been developed or are at present clinically investigated. The neuroprotective role of deep brain stimulation, antiglutamatergic therapy and apomorphine will be verified in clinical studies in the near future. This is also the case for future therapeutic approaches to restoration of the damaged nervous system, such as somatic gene therapy, implantation of genetically modified cell-lines and medically controlled and directed development of embryonic cells. The conference highlighted the role of the glia, which seems to play a key role, both in traditionally as neuroimmunological and neurodegenerative disorders classified diseases, as indicated above. The topics discussed in the book are significant for recent developments in clinical neurology and neuroscience, as shown in the current literature and at international congresses.

Neurodegenerative Diseases—Advances in Research and Treatment: 2013 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 153 pages
File Size : 46,6 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481678032

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Neurodegenerative Diseases—Advances in Research and Treatment: 2013 Edition by Anonim Pdf

Neurodegenerative Diseases—Advances in Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Tauopathies. The editors have built Neurodegenerative Diseases—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Tauopathies in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neurodegenerative Diseases—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neurodegenerative Diseases: Advances in Research and Treatment: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 202 pages
File Size : 48,5 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464924804

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Neurodegenerative Diseases: Advances in Research and Treatment: 2011 Edition by Anonim Pdf

Neurodegenerative Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Neurodegenerative Diseases. The editors have built Neurodegenerative Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neurodegenerative Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neurodegenerative Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America

Author : Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
Publisher : Frontiers Media SA
Page : 217 pages
File Size : 50,6 Mb
Release : 2018-06-21
Category : Electronic
ISBN : 9782889454945

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Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America by Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram Pdf

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.

Nervous System Diseases—Advances in Research and Treatment: 2013 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 491 pages
File Size : 49,7 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481678001

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Nervous System Diseases—Advances in Research and Treatment: 2013 Edition by Anonim Pdf

Nervous System Diseases—Advances in Research and Treatment: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Neuromuscular Diseases. The editors have built Nervous System Diseases—Advances in Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neuromuscular Diseases in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nervous System Diseases—Advances in Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Integrative Medicine for Neurodegenerative Diseases: From Basic Research to Clinical Practice

Author : Shoanan Liu,Guo-qing Zheng,Hansen Chen,Guowei Li,Xinfeng Guo
Publisher : Frontiers Media SA
Page : 108 pages
File Size : 46,6 Mb
Release : 2024-03-08
Category : Medical
ISBN : 9782832545799

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Advances in Integrative Medicine for Neurodegenerative Diseases: From Basic Research to Clinical Practice by Shoanan Liu,Guo-qing Zheng,Hansen Chen,Guowei Li,Xinfeng Guo Pdf

Neurodegenerative diseases (NDs) are disorders characterized by progressive loss of neurons and may finally lead to severe impairments even death. NDs are age-dependent disorders, growing evidence suggests that nearly all aged brains exhibit characteristic changes that are associated with neurodegeneration. As the global rapidly aging population, the prevalence of NDs is which have become the most dreaded disease of aged people. Studies report that the expenses of these older patients with NDs exceed the total medical expenses of patients with cancer and cardiovascular diseases.

Neurodegeneration: Advances in Neuroscience

Author : Elena Poole
Publisher : American Medical Publishers
Page : 227 pages
File Size : 45,8 Mb
Release : 2021-11-16
Category : Medical
ISBN : 1639273107

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Neurodegeneration: Advances in Neuroscience by Elena Poole Pdf

Neurodegeneration is the gradual loss of neurons, and neuronal structure and function. This is the cause of neurodegenerative diseases, such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, etc. Research in neurodegeneration suggests that there exists several similarities between these disorders such as induced cell death and atypical protein assemblies. DNA damage accumulation has been proposed to be the causative link between neurodegeneration and aging. Several mechanisms have been implicated in the occurrence and progression of neurodegeneration, such as protein misfolding, programmed cell death, genetic mutations, various intracellular mechanisms, etc. Protein degradation is a therapeutic option for preventing the synthesis and degradation of irregular proteins that are formed in neurodegenerative disease. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in neurodegeneration. Different approaches, evaluations and advanced studies have been included herein. The extensive content of this book provides with a thorough understanding of the subject.

Advances in Alzheimer's and Parkinson's Disease

Author : Abraham Fisher,Maurizio Memo,Fabrizio Stocchi,Israel Hanin
Publisher : Springer Science & Business Media
Page : 490 pages
File Size : 46,7 Mb
Release : 2007-12-26
Category : Medical
ISBN : 9780387720760

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Advances in Alzheimer's and Parkinson's Disease by Abraham Fisher,Maurizio Memo,Fabrizio Stocchi,Israel Hanin Pdf

This volume contains the proceedings of the 2005 ADPD conference and is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, which covering topics from immunology, neuroscience, and pharmacology to genetics and molecular biology. Possible future developments in the treatment of Alzheimer’s and Parkinson’s Diseases are also covered.

Advances in Research on Neurodegeneration

Author : Werner Poewe,Gerhard Ransmayr
Publisher : Springer Science & Business Media
Page : 150 pages
File Size : 42,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783709163696

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Advances in Research on Neurodegeneration by Werner Poewe,Gerhard Ransmayr Pdf

The book contains original articles and reviews presented at the 6th International Winter Conference on Neurodegeneration, held from November 20–23, 1997 in Kitzbühel/Austria. The aim of this conference was to present and discuss recent data on the interface between neuroimmunology and neurodegeneration, in particular susceptibility to autoimmune and neurodegenerative processes, neuroprotection and restorative treatment strategies. These issues were discussed in the light of recent developments in multiple sclerosis, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease and multisystem atrophy. The articles highlight topics, which are particularly interesting for the clinician and the neuroscientist. Some of the neuroprotective strategies have already been developed or are at present clinically investigated. The neuroprotective role of deep brain stimulation, antiglutamatergic therapy and apomorphine will be verified in clinical studies in the near future. This is also the case for future therapeutic approaches to restoration of the damaged nervous system, such as somatic gene therapy, implantation of genetically modified cell-lines and medically controlled and directed development of embryonic cells. The conference highlighted the role of the glia, which seems to play a key role, both in traditionally as neuroimmunological and neurodegenerative disorders classified diseases, as indicated above. The topics discussed in the book are significant for recent developments in clinical neurology and neuroscience, as shown in the current literature and at international congresses.