Aggregation

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Red Blood Cell Aggregation

Author : Oguz Baskurt,Björn Neu,Herbert J. Meiselman
Publisher : CRC Press
Page : 326 pages
File Size : 52,6 Mb
Release : 2011-09-28
Category : Medical
ISBN : 9781439841808

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Red Blood Cell Aggregation by Oguz Baskurt,Björn Neu,Herbert J. Meiselman Pdf

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Aggregation Functions in Theory and in Practise

Author : Humberto Bustince Sola,Javier Fernandez,Radko Mesiar,Tomasa Calvo
Publisher : Springer Science & Business Media
Page : 552 pages
File Size : 50,9 Mb
Release : 2013-06-20
Category : Technology & Engineering
ISBN : 9783642391651

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Aggregation Functions in Theory and in Practise by Humberto Bustince Sola,Javier Fernandez,Radko Mesiar,Tomasa Calvo Pdf

This volume collects the extended abstracts of 45 contributions of participants to the Seventh International Summer School on Aggregation Operators (AGOP 2013), held at Pamplona in July, 16-20, 2013. These contributions cover a very broad range, from the purely theoretical ones to those with a more applied focus. Moreover, the summaries of the plenary talks and tutorials given at the same workshop are included. Together they provide a good overview of recent trends in research in aggregation functions which can be of interest to both researchers in Physics or Mathematics working on the theoretical basis of aggregation functions, and to engineers who require them for applications.

Protein Aggregation

Author : Andrzej Stanisław Cieplak
Publisher : Springer Nature
Page : 673 pages
File Size : 40,6 Mb
Release : 2022-10-30
Category : Science
ISBN : 9781071625972

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Protein Aggregation by Andrzej Stanisław Cieplak Pdf

The volume details techniques, methods, and conceptual developments to further the study of protein aggregation with emphasis on the pleiomorphic proteins implicated in etiology of neurodegeneration. Chapters guide readers through in vitro and in vivo studies of fibrillization and liquid-liquid phase separation processes, and offer a comprehensive account of the state-of-art of structural studies of protein aggregation. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Protein Aggregation: Methods and Protocols aims to be useful and practical guide to new researchers and experts looking to expand their knowledge.

Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides

Author : Yuan Jian-min,Zhou Huan-xiang
Publisher : World Scientific
Page : 328 pages
File Size : 55,7 Mb
Release : 2017-06-02
Category : Science
ISBN : 9789813202399

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Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides by Yuan Jian-min,Zhou Huan-xiang Pdf

This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer's disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view.

Folding and Aggregation Studies in the Acylphosphatase-like Family

Author : Francesco Bemporad
Publisher : Firenze University Press
Page : 128 pages
File Size : 45,8 Mb
Release : 2009
Category : Science
ISBN : 9788884539458

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Folding and Aggregation Studies in the Acylphosphatase-like Family by Francesco Bemporad Pdf

Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.

Aggregation-Induced Emission (AIE)

Author : Jianwei Xu,Ming Hui Chua,Ben Zhong Tang
Publisher : Elsevier
Page : 698 pages
File Size : 42,9 Mb
Release : 2022-04-17
Category : Technology & Engineering
ISBN : 9780128243367

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Aggregation-Induced Emission (AIE) by Jianwei Xu,Ming Hui Chua,Ben Zhong Tang Pdf

Aggregation-Induced Emission (AIE): A Practical Guide introduces readers to the topic, guiding them through fundamental concepts and the latest advances in applications. The book covers concepts, principles and working mechanisms of AIE in AIE-active luminogens, with different classes of AIE luminogens reviewed, including polymers, three-dimensional frameworks (MOFs and COFs) and supramolecular gels. Special focus is given to the structure-property relationship, structural design strategies, targeted properties and application performance. The book provides readers with a deep understanding, not only on the fundamental principles of AIE, but more importantly, on how AIE luminogens and AIE properties can be incorporated in material development. Provides the fundamental principles, design and synthesis strategies of aggregation induced emission materials Reviews the most relevant applications in materials design for stimuli-responsive materials, biomedical applications, chemo-sensing and optoelectronics Emphasizes structural design and its connection to aggregation induced emission properties, also exploring the structure-property relationship

Aggregation of Luminophores in Supramolecular Systems

Author : Neetu Tripathi,Manoj Kumar Goshisht
Publisher : CRC Press
Page : 240 pages
File Size : 47,5 Mb
Release : 2020-05-22
Category : Science
ISBN : 9781000063370

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Aggregation of Luminophores in Supramolecular Systems by Neetu Tripathi,Manoj Kumar Goshisht Pdf

Supramolecular aggregation—driven by weak non-covalent interactions, such as van der Waals, π–π interactions, hydrogen bonding, and electrostatic—has been utilized to build sensing platforms with improved selectivity and sensitivity. Supramolecular aggregates, owing to cooperative interactions, higher sensitivity and selectivity, relatively weak and dynamic non-covalent interactions, and environmental adaptation, have achieved better sensing performance than that of molecular sensory systems that rely on sensors with delicate structures. Aggregation of Luminophores in Supramolecular System: From Mechanisms to Applications describes recent advances in supramolecular chemistry, in which the luminophores are almost non-luminescent in the molecular state, but become highly emissive in the aggregate state. These advances bring new opportunities and challenges for the development of supramolecular chemistry. The intermolecular non-covalent interactions have been considered to be the main driving forces for fabricating supramolecular systems with aggregating luminophores and have an important influence on the luminescence properties of the probes. Based on these unique properties, luminescent supramolecular aggregates have greatly promoted the development of novel materials for applications as sensors, bio-imaging agents, organic electronic devices, and in the field of drug delivery. Features:  Discussion of fundamental and interdisciplinary aspects of the aggregation in supramolecular systems.  Narration of intermolecular interactions and the photophysical phenomenon of aggregation in supramolecular systems.  Comparative discussion on recent developments in aggregation-induced quenching (AIQ) and aggregation-induced emission (AIE), and drawbacks of AIQ.  Description of the technological applications of aggregation as biological sensors, chemical sensors, organic electronic materials, and in the field of drug delivery.  A convenient format for checking formulas and definitions. This book surveys highlights of the progress made in the field of the aggregation of luminophores in supramolecular chemistry. It is hoped that the work will form a foundation (and indeed a motivation) for new workers in the area, as well as also being useful to experienced supramolecular chemists. It may also aid workers in the biological area to see Nature’s aggregation in a new light. Further, the approach employed has been designed to provide readable background material for use with graduates, senior undergraduates, research professionals, and industries.

Aggregation Operators for Various Extensions of Fuzzy Set and Its Applications in Transportation Problems

Author : Akansha Mishra,Amit Kumar
Publisher : Springer Nature
Page : 262 pages
File Size : 46,6 Mb
Release : 2020-08-19
Category : Technology & Engineering
ISBN : 9789811569982

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Aggregation Operators for Various Extensions of Fuzzy Set and Its Applications in Transportation Problems by Akansha Mishra,Amit Kumar Pdf

This book introduces readers to the fundamentals of transportation problems under the fuzzy environment and its extensions. It also discusses the limitations and drawbacks of (1) recently proposed aggregation operators under the fuzzy environment and its various extensions; (2) recently proposed methods for solving transportation problems under the fuzzy environment; and (3) recently proposed methods for solving transportation problems under the intuitionistic fuzzy environment. In turn, the book proposes simplified methods to overcome these limitations.

Early Stage Protein Misfolding and Amyloid Aggregation

Author : Anonim
Publisher : Academic Press
Page : 320 pages
File Size : 45,9 Mb
Release : 2017-02-01
Category : Science
ISBN : 9780128122525

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Early Stage Protein Misfolding and Amyloid Aggregation by Anonim Pdf

Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists. Provides comprehensive reviews and current advances Presents a wide range of perspectives on specific subjects Includes valuable reference material for advanced undergraduates, graduate students, and professional scientists

Handbook of Aggregation-Induced Emission, Volume 2

Author : Youhong Tang,Ben Zhong Tang
Publisher : John Wiley & Sons
Page : 628 pages
File Size : 53,8 Mb
Release : 2022-03-28
Category : Science
ISBN : 9781119642985

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Handbook of Aggregation-Induced Emission, Volume 2 by Youhong Tang,Ben Zhong Tang Pdf

The second volume of the ultimate reference on the science and applications of aggregation-induced emission The Handbook of Aggregation-Induced Emission explores foundational and advanced topics in aggregation-induced emission, as well as cutting-edge developments in the field, celebrating twenty years of progress and achievement in this important and interdisciplinary field. The three volumes combine to offer readers a comprehensive and insightful interpretation accessible to both new and experienced researchers working on aggregation-induced emission. In Volume 2: Typical AIEgens Design, the editors address the design and synthesis of typical AIEgens that have made significant contributions to aggregation-induced emission research. Recent advances in the development of aggregation-induced emission systems are discussed and the book covers novel aggregation-induced emission systems in small molecule organogels, polymersomes, metal-organic coordination complexes and metal nanoclusters. Readers will also discover: A thorough introduction to the synthesis and applications of tetraphenylpyrazine-based AIEgens, AIEgens based on 9,10-distyrylanthracene , and the Salicylaldehyde Schiff base Practical discussions of aggregation-induced emission from the sixth main group and fluorescence detection of dynamic aggregation processes using AIEgens Coverage of cyclic triimidazole derivatives and the synthesis of multi-phenyl-substituted pyrrole based materials and their applications Perfect for academic researchers working on aggregation-induced emission, this set of volumes is also ideal for professionals and students in the fields of photophysics, photochemistry, materials science, optoelectronic materials, synthetic organic chemistry, macromolecular chemistry, polymer science, and biological sciences.

Power Aggregation Operators of Simplified Neutrosophic Sets and Their Use in Multi-attribute Group Decision Making

Author : Chunfang Liu,Yuesheng Luo
Publisher : Infinite Study
Page : 10 pages
File Size : 46,8 Mb
Release : 2024-06-03
Category : Electronic
ISBN : 8210379456XXX

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Power Aggregation Operators of Simplified Neutrosophic Sets and Their Use in Multi-attribute Group Decision Making by Chunfang Liu,Yuesheng Luo Pdf

The simplified neutrosophic set (SNS) is a useful generalization of the fuzzy set that is designed for some practical situations in which each element has different truth membership function, indeterminacy membership function and falsity membership function.

Collected Works of W.M. Gorman: Separability and aggregation

Author : William Moore Gorman
Publisher : Oxford University Press
Page : 512 pages
File Size : 40,5 Mb
Release : 1995
Category : Business & Economics
ISBN : 0198285213

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Collected Works of W.M. Gorman: Separability and aggregation by William Moore Gorman Pdf

This volume brings together for the first time the important work of W.M. (Terence) Gorman, a major figure in the development of economics during the past 40 years. His publications on separability, aggregation, duality and demand are recongized as fundamental contributions to economic theory.

Exponential Aggregation Operator of Interval Neutrosophic Numbers and Its Application in Typhoon Disaster Evaluation

Author : Ruipu Tan,Wende Zhang,Shengqun Chen
Publisher : Infinite Study
Page : 22 pages
File Size : 52,8 Mb
Release : 2024-06-03
Category : Electronic
ISBN : 8210379456XXX

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Exponential Aggregation Operator of Interval Neutrosophic Numbers and Its Application in Typhoon Disaster Evaluation by Ruipu Tan,Wende Zhang,Shengqun Chen Pdf

In recent years, typhoon disasters have occurred frequently and the economic losses caused by them have received increasing attention. This study focuses on the evaluation of typhoon disasters based on the interval neutrosophic set theory.

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A

Author : Anonim
Publisher : Academic Press
Page : 248 pages
File Size : 41,8 Mb
Release : 2021-11-06
Category : Science
ISBN : 9780323907408

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Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A by Anonim Pdf

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Emitting light is a fascinating photophysical phenomenon, its different forms have brought the attention of various disciplines of natural sciences for centuries. In the modern era of scientific generation, short-lived fluorescence light and its long-lived counterpart phosphorescence light has been employed for several chemo-sensing, bio-sensing, and bioimaging applications. The aggregation induced emission (AIE) phenomenon has appeared as a wand of modern science to convert aggregation-caused quenching (ACQ) materials into AIE active materials for a wide range of biomedical applications including biosensing, bioimaging and localization of molecules for better understanding of molecular mechanisms. This volume covers a wide range of topics which are not currently available in a single volume, including ACQ & AIE concept development; intracellular pH, temperature and viscosity sensing; imaging of cell membrane, lipid droplet, lysosome, and mitochondria; biosensing and Imaging of bacteria; nucleus and nucleic acid imaging. Offers a basic understanding of AIE principle, mechanism and transformation of ACQ active to AIE active materials Elucidates nucleus and nucleic acid imaging applications of AIE active small molecules Describes imaging of cell membrane, lipid droplet, lysosome, and mitochondria of AIE molecules

Aggregation Functions

Author : Michel Grabisch
Publisher : Cambridge University Press
Page : 481 pages
File Size : 44,6 Mb
Release : 2009-07-09
Category : Computers
ISBN : 9780521519267

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Aggregation Functions by Michel Grabisch Pdf

A rigorous and self-contained exposition of aggregation functions and their properties.