Red Blood Cell Aggregation

Author : Oguz Baskurt,Björn Neu,Herbert J. Meiselman
Publisher : CRC Press
Page : 326 pages
File Size : 48,5 Mb
Release : 2011-09-28
Category : Medical
ISBN : 9781439841808

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Red Blood Cell Aggregation by Oguz Baskurt,Björn Neu,Herbert J. Meiselman Pdf

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Author : Oguz Baskurt,Björn Neu,Herbert J. Meiselman
Publisher : CRC Press
Page : 318 pages
File Size : 53,7 Mb
Release : 2011-09-28
Category : Medical
ISBN : 9781439841815

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Red Blood Cell Aggregation by Oguz Baskurt,Björn Neu,Herbert J. Meiselman Pdf

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.

Author : Haim I. Bicher
Publisher : Unknown
Page : 218 pages
File Size : 43,9 Mb
Release : 1972
Category : Medical
ISBN : UOM:39015000889801

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Blood Cell Aggregation in Thrombotic Processes by Haim I. Bicher Pdf

Author : F. Family,D.P. Landau
Publisher : Elsevier
Page : 294 pages
File Size : 46,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780444596581

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Kinetics of Aggregation and Gelation by F. Family,D.P. Landau Pdf

Kinetics of Aggregation and Gelation presents the proceedings of the International Topical Conference on Kinetics of Aggregation and Gelation held on April 2-4, 1984 in Athens, Georgia. The purpose of the conference was to bring together international experts from a wide variety of backgrounds who are studying phenomena inherently similar to the formation of large clusters by the union of many separate, small elements, to present and exchange ideas on new theories and results of experimental and computer simulations. This book is divided into 57 chapters, each of which represents an oral presentation that is part of a unified whole. The book begins with a presentation on fractal concepts in aggregation and gelation, followed by presentations on topics such as aggregative fractals called ""squigs""; multi-particle fractal aggregation; theory of fractal growth processes; self-similar structures; and interface dynamics. Other chapters cover addition polymerization and related models; the kinetic gelation model; a new model of linear polymers; red cell aggregation kinetics; the Potts Model; aggregation of colloidal silica; the ballistic model of aggregation; stochastic dynamics simulation of particle aggregation; particle-cluster aggregation; kinetic clustering of clusters; computer simulations of domain growth; and perspectives in the kinetics of aggregation and gelation. This book will be of interest to practitioners in the fields of chemistry, theoretical physics, and materials engineering.

Author : S. Chien,John A. Dormandy,E. Ernst,A. Matrai
Publisher : Springer Science & Business Media
Page : 387 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400942851

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Clinical Hemorheology by S. Chien,John A. Dormandy,E. Ernst,A. Matrai Pdf

The task the editors have set themselves is to survey the field of clinical hemorheology from basic principles to up-to-date research. It is only in a new science like this that it is possible to span the whole field in a book of this size. Hemorheology, as a new approach to the study and management of a wide range of circulatory diseases, is now beginning to appear with increasing frequency in general as well as specialized medical journals. Hemorheology is also just beginning to creep into the undergraduate medical curriculum. Therefore, the majority of graduate doctors are unequipped to assess the place of hemorheology in the overall framework of circulatory physiology and pathology or to assess its relevance to their everyday practice. It is hoped that this book will fill this gap. The approach of the book is interdisciplinary. The first part deals with basic principles of blood flow, circulation and hemorheology. It has been written with the general doctor in mind, who has no special knowledge of hemodynamics and rheological concepts, terminology or methodology. To maintain the emphasis on practical clinical applications, all the chapters in the second part of the book have been written by clinical specialists practicing in the individual areas of disease. The book is so designed that clinicians may be able to read the relevant chapters in the second part of the book in isolation, using the basic science aspects contained in the first part of the book as reference chapters.

Author : O.K. Baskurt,M.R. Hardeman,M.W. Rampling
Publisher : IOS Press
Page : 468 pages
File Size : 49,6 Mb
Release : 2007-10-03
Category : Medical
ISBN : 9781607502630

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Handbook of Hemorheology and Hemodynamics by O.K. Baskurt,M.R. Hardeman,M.W. Rampling Pdf

This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.

Author : Annie Viallat,Manouk Abkarian
Publisher : CRC Press
Page : 457 pages
File Size : 51,9 Mb
Release : 2019-12-09
Category : Medical
ISBN : 9781315395135

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Dynamics of Blood Cell Suspensions in Microflows by Annie Viallat,Manouk Abkarian Pdf

The first book to provide a physical perspective of blood microcirculation Draws attention to the potential of this physical approach for novel applications in medicine Edited by specialists in this field, with chapter contributions from subject area specialists

Author : Douglas MacN. Surgenor
Publisher : Academic Press
Page : 782 pages
File Size : 48,7 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483257501

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The Red Blood Cell by Douglas MacN. Surgenor Pdf

The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood cell. This book discusses the transport through red cell membranes; carrier-mediated glucose transport across human red cell membranes; and metabolism of methemoglobin in human erythrocytes. The interaction of oxygen and carbon dioxide with hemoglobin at the molecular level; physiological role of the oxyhemoglobin dissociation curve; hemoglobinopathies; and thalassemia syndromes are also deliberated. This publication likewise covers the red cell genetic polymorphisms; biological life of the red cell; clinical indications for red cells and blood; and biophysical behavior of red cells in suspensions. Other topics include the electrokinetic behavior of red cells; erythrocyte as a biopsy tissue in the evaluation of nutritional status; and knowledge of red cell purine and pyrimidine metabolism coming from the study of human disease. This volume is recommended for students, researchers, teachers, and physicians aiming to acquire knowledge of the red blood cell.

Author : Haim I. Bicher,Rogoff Welcome Medical Research Institute
Publisher : Unknown
Page : 546 pages
File Size : 48,5 Mb
Release : 1968
Category : Blood coagulation disorders
ISBN : OCLC:8013891

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Blood Cell Aggregation in Thrombotic Processes by Haim I. Bicher,Rogoff Welcome Medical Research Institute Pdf

Author : Daniel Flormann
Publisher : Unknown
Page : 128 pages
File Size : 50,7 Mb
Release : 2017
Category : Electronic
ISBN : OCLC:989517477

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Physical Characterization of Red Blood Cell Aggregation by Daniel Flormann Pdf

Author : A.W.M.M. Koopman-van Gemert
Publisher : BoD – Books on Demand
Page : 130 pages
File Size : 48,9 Mb
Release : 2017-07-05
Category : Medical
ISBN : 9789535133193

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Transfusion Medicine and Scientific Developments by A.W.M.M. Koopman-van Gemert Pdf

Transfusion Medicine and Scientific Developments focuses on unknown aspects of blood cells and transfusion practice. Blood transfusion medicine has become a sophisticated and specialized field of medicine. Some aspects will be discussed in this book. The book has been divided into three sections. The first section includes chapters describing the immunological and coagulation-assisting functions of red blood cells and methods to measure their life span. The second section discusses the role of platelets in inflammatory processes. The third section reviews functional dose of RBC transfusions and transfusion practice in various clinical settings.

Author : Gordon D.O. Lowe
Publisher : CRC Press
Page : 237 pages
File Size : 40,9 Mb
Release : 2019-06-04
Category : Medical
ISBN : 9780429523298

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Clinical Blood Rheology by Gordon D.O. Lowe Pdf

Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.

Author : Ayesha Sohail,Zhiwu Li
Publisher : John Wiley & Sons
Page : 296 pages
File Size : 43,5 Mb
Release : 2019-01-14
Category : Science
ISBN : 9783527344710

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Computational Approaches in Biomedical Nano-Engineering by Ayesha Sohail,Zhiwu Li Pdf

This book comprehensively and systematically treats modern understanding of the Nano-Bio-Technology and its therapeutic applications. The contents range from the nanomedicine, imaging, targeted therapeutic applications, experimental results along with modelling approaches. It will provide the readers with fundamentals on computational and modelling aspects of advanced nano-materials and nano-technology specifically in the field of biomedicine, and also provide the readers with inspirations for new development of diagnostic imaging and targeted therapeutic applications.

Author : Michael R. Pinsky,Laurent Brochard,Jordi Mancebo
Publisher : Springer Science & Business Media
Page : 367 pages
File Size : 50,8 Mb
Release : 2007-05-19
Category : Medical
ISBN : 9783540373636

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Applied Physiology in Intensive Care Medicine by Michael R. Pinsky,Laurent Brochard,Jordi Mancebo Pdf

Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primarily on physiologic principles in determining the best treatments and response to therapy. However, the physiologic foundation present in practicing physicians is uneven and occasionally supported more by habit or prior training than science. A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o cia t ed r e vie w a r tic les o v er t h e s a m e in t er val t ha t a ls o addr ess e d t hes e cen tral issues.

Author : Kandice Kottke-Marchant,Bruce Davis
Publisher : John Wiley & Sons
Page : 777 pages
File Size : 53,5 Mb
Release : 2012-06-06
Category : Medical
ISBN : 9781444398571

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Laboratory Hematology Practice by Kandice Kottke-Marchant,Bruce Davis Pdf

Expertly edited and endorsed by the International Society for Laboratory Hematology, this is the newest international textbook on all aspects of laboratory hematology. Covering both traditional and cutting-edge hematology laboratory technology this book emphasizes international recommendations for testing practices. Illustrative case studies on how technology can be used in patient diagnosis are included. Laboratory Hematology Practice is an invaluable resource for all those working in the field.