An Introduction To Biomedical Research Facilities Predesign Of Animal Research Facilities

Author : Jack Hessler,Noel Lehner
Publisher : Academic Press
Page : 520 pages
File Size : 47,5 Mb
Release : 2011-04-28
Category : Science
ISBN : 0080919219

Get Book

Planning and Designing Research Animal Facilities by Jack Hessler,Noel Lehner Pdf

Research institutions have or are planning to build, expand and renovate animal research facilities to keep up with the demands of biomedical research caused in part by growth in the use of genetically altered rodents and the upsurge of research in infectious diseases. Properly designed facilities greatly facilitate effective management and high-quality day-to-day animal care that is required to optimally support animal research and testing. There are multiple solutions to address the myriad of factors that influence the design and construction of animal research facilities. There is no “best design applicable for all facilities and arguably not even a single “best design for a given facility. For this reason, Planning and Designing Research Animal Facilities is not intended to be a “how to book. The goal is to cover the basic programmatic requirements of animal research facilities, provide ideas for meeting those requirements while, hopefully, stimulating the creative process in which designers in consultation with those who work in animal research facilities generate even better ideas. That is how progress has been made and will continue to be made. Facilitates communication between the parties involved in planning and designing animal facilities by providing contemporary information, and stimulating creativity that will help lead to wise decisions and advance the knowledge base for planning, design and constructing animal research facilities

Author : J. Paul Guyer, P.E., R.A.
Publisher : Guyer Partners
Page : 28 pages
File Size : 50,9 Mb
Release : 2021-08-17
Category : Technology & Engineering
ISBN : 8210379456XXX

Get Book

An Introduction to Biomedical Research Facilities: Predesign of Animal Research Facilities by J. Paul Guyer, P.E., R.A. Pdf

Introductory technical guidance for professional engineers and construction managers interested in design of biomedical animal research facilities. Here is what is discussed: 1. INTRODUCTION 2. PROJECT PROGRAMMING

Author : J. Paul Guyer, P.E., R.A.
Publisher : Guyer Partners
Page : 26 pages
File Size : 41,8 Mb
Release : 2021-08-19
Category : Technology & Engineering
ISBN : 8210379456XXX

Get Book

An Introduction to Biomedical Research Facilities: Design of Animal Research Facilities by J. Paul Guyer, P.E., R.A. Pdf

Introductory technical guidance for professional engineers, architects and construction managers interested in design of biomedical animal research facilities. Here is what is discussed: DESIGN REQUIREMENTS 2. MODULAR DESIGN 3. MATERIALS AND FINISHES 4. ARF SECURITY 5. DESIGN CONSIDERATIONS 6. UTILITY SYSTEMS

Author : Pierce K. H. Chow,Robert T. H. Ng,Bryan E. Ogden
Publisher : World Scientific
Page : 309 pages
File Size : 46,5 Mb
Release : 2008
Category : Medical
ISBN : 9789812812025

Get Book

Using Animal Models in Biomedical Research by Pierce K. H. Chow,Robert T. H. Ng,Bryan E. Ogden Pdf

Ch. 1. Scientific considerations and choice of species. ch. 1.1. The rationale for the use of animal models in biomedical research / Pierce Chow. ch. 1.2. Experimental animal models in biomedical resarch / Robert Ng. ch. 1.3. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. 2. Regulatory considerations in the use of animal models. ch. 2.1. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. ch. 2.2. The functions of the institutional animal care and use committee / Pierce Chow. ch. 2.3. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. ch. 2.4. The 3R's, research variables and the use of alternatives / Hock Soo Ong. ch. 2.5. Use of statistics as determinant for number of animals used / Huihua Li. ch. 2.6. The advantages of accreditation with AAALAC / Bryan Ogden -- ch. 3. Animal handling and surgical procedures. ch. 3.1. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. ch. 3.2. Blood collection from laboratory animals / Jason Villano. ch. 3.3. Antibiotic coverage and therapy / Darvi Sergio. ch. 3.4. Animal preparation and transport / Robert Ng. ch. 3.5. Preparation and implementation of animal surgery / Robert Ng. ch. 3.6. Animal intubation / Robert Ng. ch. 3.7. Anaesthesia and maintenance of homeostasis / Robert Ng. ch. 3.8. Animal euthanasia / Darvi Sergio. ch. 3.9. Rodent sentinel programme / Peik Khin Tan -- ch. 4. Basic animal investigative methods. ch. 4.1. Bioimaging in animals / David Ng [und weitere]. ch. 4.2. Histology sampling and techniques / In Chin Song. ch. 4.3. Animal tissue perfusion and preservation / Robert Ng. ch. 4.4. Animal cell culture / Kai Zhang and Peggy Yong. ch. 4.5. Application of microsurgical techniques in animal research / Bien Keem Tan [und weitere] -- ch. 5. Animal welfare considerations. ch. 5.1. Species specific caging configuration and design / Cindy Phua. ch. 5.2. Postoperative care and pain management / Jason Villano. ch. 5.3. Animal feeds and nutritional requirements / Peik Khin Tan -- ch. 6. Safety management of an animal facility. ch. 6.1. Occupational health and safety programme / Angela Goh. ch. 6.2. New employee and external users orientation / Inria Kurniawan Then. ch. 6.3. Radiation safety awareness in animal research / S. Somanesan. ch. 6.4. Emergency crisis management / Irene Kee. ch. 6.5. Zoonoses and laboratory animal allergies / Jason Villano -- ch. 7. Supporting facilities design. ch. 7.1. Clinical skills laboratory / Robert Ng. ch. 7.2. Animal research supporting laboratories / Robert Ng. ch. 7.3. Animal research and housing facilities / Robert Ng -- ch. 8. The development of comprehensive animal facilities in Singapore. ch. 8.1. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng

Author : National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 113 pages
File Size : 46,7 Mb
Release : 1988-02-01
Category : Science
ISBN : 9780309038393

Get Book

Use of Laboratory Animals in Biomedical and Behavioral Research by National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research Pdf

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee to Update Science, Medicine, and Animals
Publisher : National Academies Press
Page : 56 pages
File Size : 47,7 Mb
Release : 2004-11-21
Category : Science
ISBN : 9780309088947

Get Book

Science, Medicine, and Animals by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee to Update Science, Medicine, and Animals Pdf

Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association.

Author : Mark A. Suckow,Fred A. Douglas,Robert H. Weichbrod
Publisher : CRC Press
Page : 409 pages
File Size : 49,7 Mb
Release : 2001-11-28
Category : Medical
ISBN : 9781420038842

Get Book

Management of Laboratory Animal Care and Use Programs by Mark A. Suckow,Fred A. Douglas,Robert H. Weichbrod Pdf

The management of biomedical research using animals has become increasingly complex due to new technology, increased regulatory oversight, and recognition of the need for animals free of disease and distress. Within this changing environment, individuals charged with the management of laboratory animal facilities have a substantial responsibility to the institution, the public, and the animals. Management of Laboratory Animals Care and Use Programs provides both factual and theoretical information drawn from the substantial experience of authors who are noted experts in the field. This book will provide individuals with the basic knowledge and information necessary to meet typical professional challenges. A co-publication with the American Association for Laboratory Animal Science, this valuable book serves as the text for the Certified Manager Animal Resources (CMAR) exam.

Author : National Research Council,Institute for Laboratory Animal Research,Committee on Cost of and Payment for Animal Research
Publisher : National Academies Press
Page : 164 pages
File Size : 48,7 Mb
Release : 2001-01-18
Category : Technology & Engineering
ISBN : 9780309072618

Get Book

Strategies That Influence Cost Containment in Animal Research Facilities by National Research Council,Institute for Laboratory Animal Research,Committee on Cost of and Payment for Animal Research Pdf

Care and use of animals in research are expensive, prompting efforts to contain or reduce costs. Components of those costs are personnel, regulatory compliance, veterinary medical care, and laboratory animal management, equipment, and procedures. Many efforts have been made to control and reduce personnel costs, the largest contributing factor to cost, through better facility and equipment design, more efficient use of personnel, and automation of many routine operations. However, there has been no comprehensive, recent analysis of the various cost components or examination of the strategies that have been proven or are purported to decrease the cost of animal facility operation. Strategies that Influence Cost Containment in Animal Research Facilities examines the current interpretation of governmental policy (Office of Management and Budget Circular A-21) concerning institutional reimbursement for overhead costs of an animal research facility and describes methods for economically operating an animal research facility. This report develops recommendations by which federal auditors and research institutions can establish what cost components of research animal facilities should be charged to institutions' indirect cost pool and what animal research facility cost components should be included in the per diem charges to investigators, and assesses the financial and scientific ramifications that these criteria would have among federally funded institutions. Further, the report determines the cost components of laboratory animal care and use in biomedical research and assesses and recommends methods of cost containment for institutions maintaining animals for biomedical research.

Author : American Institute of Architects
Publisher : Amer Inst of Architects
Page : 91 pages
File Size : 45,8 Mb
Release : 1999-01-01
Category : Medical laboratories
ISBN : 1879304953

Get Book

Guidelines for Planning and Design of Biomedical Research Laboratory Facilities by American Institute of Architects Pdf

Author : Anonim
Publisher : Unknown
Page : 484 pages
File Size : 41,9 Mb
Release : 2000
Category : Animal experimentation
ISBN : PURD:32754071531820

Get Book

Using Animals in Intramural Research by Anonim Pdf

Author : National Institutes of Health (U.S.). Division of Research Resources
Publisher : Unknown
Page : 40 pages
File Size : 54,5 Mb
Release : 1979
Category : Federal aid to medical research
ISBN : MINN:30000010687055

Get Book

Program Highlights by National Institutes of Health (U.S.). Division of Research Resources Pdf

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
Publisher : National Academies Press
Page : 246 pages
File Size : 44,6 Mb
Release : 2011-01-27
Category : Science
ISBN : 9780309154000

Get Book

Guide for the Care and Use of Laboratory Animals by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals Pdf

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Author : B. Taylor Bennett,Marilyn J. Brown,John C. Schofield
Publisher : Unknown
Page : 140 pages
File Size : 44,9 Mb
Release : 1990
Category : Animal experimentation
ISBN : UOM:39015033087555

Get Book

Essentials for Animal Research by B. Taylor Bennett,Marilyn J. Brown,John C. Schofield Pdf

Nesse manual sao desenvolvidas as linhas essenciais para o curso de Pesquisa Animal.

Author : Dorte Bratbo Sørensen,Sylvie Cloutier,Brianna N. Gaskill
Publisher : CRC Press
Page : 207 pages
File Size : 49,5 Mb
Release : 2020-10-14
Category : Medical
ISBN : 9780429602054

Get Book

Animal-centric Care and Management by Dorte Bratbo Sørensen,Sylvie Cloutier,Brianna N. Gaskill Pdf

The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch’s definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

Author : Institute of Laboratory Animal Research,Commission on Life Sciences,National Research Council
Publisher : National Academies Press
Page : 181 pages
File Size : 41,7 Mb
Release : 1996-07-23
Category : Science
ISBN : 9780309132626

Get Book

Guide for the Care and Use of Laboratory Animals by Institute of Laboratory Animal Research,Commission on Life Sciences,National Research Council Pdf

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and includes extensive references. It is organized around major components of animal use: Institutional policies and responsibilities. The committee discusses areas that require policy attention: the role and function of the Institutional Animal Care and Use Committee, protocols for animal care and use, occupational health and safety, personnel qualifications, and other areas. Animal environment, husbandry, and management. The committee offers guidelines on how to design and run a management program, addressing environment, nutrition, sanitation, behavioral and social issues, genetics, nomenclature, and more. Veterinary care. The committee discusses animal procurement and transportation, disease and preventive medicine, and surgery. The Guide addresses pain recognition and relief and issues surrounding euthanasia. Physical plant. The committee identifies design and construction issues, providing guidelines for animal-room doors, drainage, noise control, surgery, and other areas. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. This revision will be important to researchers, animal care technicians, facilities managers, administrators at research institutions, policymakers involved in research issues, and animal welfare advocates.