An Introduction To Toxicology

An Introduction To Toxicology Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of An Introduction To Toxicology book. This book definitely worth reading, it is an incredibly well-written.

An Introduction to Toxicology

Philip C. Burcham
An Introduction to Toxicology Book PDF

Author : Philip C. Burcham
Publisher : Springer Science & Business Media
Page : 338 pages
File Size : 49,5 Mb
Release : 2013-11-19
Category : Medical
ISBN : 9781447155539

Get Book

An Introduction to Toxicology by Philip C. Burcham Pdf

This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

An Introduction to Interdisciplinary Toxicology

Carey N. Pope,Jing Liu
An Introduction to Interdisciplinary Toxicology Book PDF

Author : Carey N. Pope,Jing Liu
Publisher : Academic Press
Page : 644 pages
File Size : 46,9 Mb
Release : 2020-03-06
Category : Medical
ISBN : 9780128136027

Get Book

An Introduction to Interdisciplinary Toxicology by Carey N. Pope,Jing Liu Pdf

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

Introduction to Toxicology and Food

Tomris Altug
Introduction to Toxicology and Food Book PDF

Author : Tomris Altug
Publisher : CRC Press
Page : 170 pages
File Size : 47,9 Mb
Release : 2002-07-30
Category : Technology & Engineering
ISBN : 9780849314568

Get Book

Introduction to Toxicology and Food by Tomris Altug Pdf

With growing interest in the safety of foods, knowledge of food toxicology is gaining more importance every day. Introduction to Toxicology and Food provides a concise overview of both the science of toxicology and food toxicology. It presents easy-to-understand explanations of the concepts and principles of toxicology as a science, the toxicants found in foods, and naturally occurring antitoxic/anticarcinogenic substances in foods. It examines the uses, harmful effects, and safety aspects of a variety of toxicants, including natural toxicants, contaminants, and food additives. The book begins with a general overview of the concepts and principles of toxicology. It describes its history and branches, toxic doses, stages of toxication, effect mechanisms of toxins, and toxicity tests. Then it covers the substances in our foods that have toxicological significance, such as natural sources of toxicants, contaminants, and food additives. Finally, the book presents information about "chemopreventers" - those foods and food components that have antimutagenic or anticarcinogenic effects. With its easy-to-read style and its clear discussions of the science of toxicology, food toxicology, and chemopreventers, Introduction to Toxicology and Food is an ideal text for an undergraduate course in food toxicology and a useful guide for food scientists.

Introduction to Toxicology, Third Edition

John Timbrell
Introduction to Toxicology Third Edition Book PDF

Author : John Timbrell
Publisher : CRC Press
Page : 238 pages
File Size : 40,6 Mb
Release : 2001-11-15
Category : Medical
ISBN : 0415247632

Get Book

Introduction to Toxicology, Third Edition by John Timbrell Pdf

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

An Introduction to Aquatic Toxicology

Mikko Nikinmaa
An Introduction to Aquatic Toxicology Book PDF

Author : Mikko Nikinmaa
Publisher : Elsevier
Page : 253 pages
File Size : 44,5 Mb
Release : 2014-07-01
Category : Science
ISBN : 9780124115811

Get Book

An Introduction to Aquatic Toxicology by Mikko Nikinmaa Pdf

An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges Includes guidance on testing methods and a glossary of aquatic toxicology terms

A Textbook of Modern Toxicology

Ernest Hodgson,Patricia E. Levi
A Textbook of Modern Toxicology Book PDF

Author : Ernest Hodgson,Patricia E. Levi
Publisher : McGraw-Hill Medical Publishing
Page : 518 pages
File Size : 45,8 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015041081293

Get Book

A Textbook of Modern Toxicology by Ernest Hodgson,Patricia E. Levi Pdf

This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.

Essentials of Toxicology for Health Protection

David Baker
Essentials of Toxicology for Health Protection Book PDF

Author : David Baker
Publisher : Oxford University Press
Page : 368 pages
File Size : 43,8 Mb
Release : 2012-03-15
Category : Medical
ISBN : 0199652546

Get Book

Essentials of Toxicology for Health Protection by David Baker Pdf

Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.

Modern Poisons

Alan Kolok
Modern Poisons Book PDF

Author : Alan Kolok
Publisher : Island Press
Page : 224 pages
File Size : 46,8 Mb
Release : 2016-05-05
Category : Health & Fitness
ISBN : 9781610913829

Get Book

Modern Poisons by Alan Kolok Pdf

Modern Poisons bridges the gap between traditional toxicology textbooks and journal articles on cutting-edge science. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts such as the dose-response relationship and goes on to show exactly how chemicals enter the body and elicit their toxic effect. Kolok then traces toxicology's development, from studies of endocrine-disrupting chemicals in toiletries to the emerging science on prions and epigenetics. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of--and curiosity about--this fast-changing field.

Introduction to Food Toxicology

Takayuki Shibamoto,Leonard F. Bjeldanes
Introduction to Food Toxicology Book PDF

Author : Takayuki Shibamoto,Leonard F. Bjeldanes
Publisher : Academic Press
Page : 231 pages
File Size : 44,8 Mb
Release : 2012-12-02
Category : Technology & Engineering
ISBN : 9780080925776

Get Book

Introduction to Food Toxicology by Takayuki Shibamoto,Leonard F. Bjeldanes Pdf

The area of food toxicology currently has a high profile of interest in the food industry, universities, and government agencies, and is certainly of great concern to consumers. There are many books which cover selected toxins in foods (such as plant toxins, mycotoxins, pesticides, or heavy metals), but this book represents the first pedagogic treatment of the entire range of toxic compounds found naturally in foods or introduced by industrial contamination or food processing methods. Featuring coverage of areas of vital concern to consumers, such as toxicological implications of food adulteration (as seen in ethylene glycol in wines or the Spanish olive oil disaster) or pesticide residues, Introduction to Food Toxicology will be of interest to students in toxicology, environmental studies, and dietetics as well as anyone interested in food sources and public health issues. The number of students who are interested in toxicology has increased dramatically in the past several years. Issues related to toxic materials have received more and more attention from the public. The issues and potential problems are reported almost daily by the mass media, including television, newspapers, and magazines. Major misunderstandings and confusion raised by those reports are generally due to lack of basic knowledge about toxicology among consumers. This textbook provides the basic principles of food toxicology in order to help the general public better understand the real problems of toxic materials in foods. Principles of toxicology Toxicities of chemicals found in foods Occurrence of natural toxins in plant and animal foodstuffs Food contamination caused by industry Toxic chemicals related to food processing Food additives Microbial toxins in foods

Introduction to Toxicology

John Timbrell,Frank A. Barile
Introduction to Toxicology Book PDF

Author : John Timbrell,Frank A. Barile
Publisher : CRC Press
Page : 317 pages
File Size : 53,6 Mb
Release : 2023-02-27
Category : Medical
ISBN : 9781000834451

Get Book

Introduction to Toxicology by John Timbrell,Frank A. Barile Pdf

As with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced. Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides on human health, animal welfare, and the stability and maintenance of the ecosystem continue to highlight toxicology as an important and growing scientific discipline. Key features: Comprehensive coverage of the field of toxicology which illustrates its importance to and impact on society Uses pertinent examples, tables, and diagrams to aid understanding with learning objectives, summaries, questions, and answers for each chapter Clearly and concisely written and presented concepts for easy comprehension by toxicology, biomedical, and health science students Examines the complex interactions associated with toxicological events Covers the effect of toxins on biological and physiological systems This book successfully condenses the diffuse literature in the field into an accessible and readable text, made easier with the insertion of many tables and figures. It introduces fundamental concepts and builds upon these using topical and relevant historical examples. Its improved format includes learning objectives and summaries of each chapter, as well as questions and answers suitable for self-assessment. This latest edition is an invaluable resource for undergraduate and graduate toxicology students, as well as an introductory text for other health care students and professionals. The book also functions as a comprehensive introductory reference text for environmental scientists, medical biologists and chemists, chemical engineers, and regulatory agencies, with interests in toxicologically related areas.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Ali S. Faqi
A Comprehensive Guide to Toxicology in Nonclinical Drug Development Book PDF

Author : Ali S. Faqi
Publisher : Elsevier
Page : 1074 pages
File Size : 47,6 Mb
Release : 2024-02-11
Category : Medical
ISBN : 9780323984621

Get Book

A Comprehensive Guide to Toxicology in Nonclinical Drug Development by Ali S. Faqi Pdf

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy Includes the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Molecular and Cellular Toxicology

Lesley Stanley
Molecular and Cellular Toxicology Book PDF

Author : Lesley Stanley
Publisher : John Wiley & Sons
Page : 471 pages
File Size : 43,5 Mb
Release : 2014-04-02
Category : Medical
ISBN : 9781118526019

Get Book

Molecular and Cellular Toxicology by Lesley Stanley Pdf

Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of ‘omics methods, high throughput screening (HTS) techniques and molecular imaging technologies. This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals.

Toxicology and Risk Assessment

Helmut Greim,Robert Snyder
Toxicology and Risk Assessment Book PDF

Author : Helmut Greim,Robert Snyder
Publisher : John Wiley & Sons
Page : 840 pages
File Size : 49,8 Mb
Release : 2018-08-10
Category : Science
ISBN : 9781119135920

Get Book

Toxicology and Risk Assessment by Helmut Greim,Robert Snyder Pdf

Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

Introduction to Environmental Toxicology

Wayne G. Landis,Ruth M. Sofield,Ming-Ho Yu
Introduction to Environmental Toxicology Book PDF

Author : Wayne G. Landis,Ruth M. Sofield,Ming-Ho Yu
Publisher : Unknown
Page : 0 pages
File Size : 45,7 Mb
Release : 2018
Category : Biotic communities
ISBN : 1498750427

Get Book

Introduction to Environmental Toxicology by Wayne G. Landis,Ruth M. Sofield,Ming-Ho Yu Pdf

Introduction to environmental toxicology -- Frameworks and paradigms for environmental toxicology -- Overview of toxicity testing methods -- The analysis of exposure-response -- The fate and transport of contaminants -- Uptake and modes of action -- Modification in toxic responses, mixtures and climate change -- Inorganic gaseous pollutants -- Fluoride as a contaminant of developing economies -- Metals -- Biotransformation, detoxification, and biodegradation -- Ecological effects from biomarkers to populations -- Ecological effects: community to landscape scales of toxicological impacts -- Ecological risk assessment -- Index.

Principles of Toxicology Testing, Second Edition

Frank A Barile
Principles of Toxicology Testing Second Edition Book PDF

Author : Frank A Barile
Publisher : CRC Press
Page : 368 pages
File Size : 41,5 Mb
Release : 2013-04-02
Category : Medical
ISBN : 9781842145289

Get Book

Principles of Toxicology Testing, Second Edition by Frank A Barile Pdf

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development. As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing. Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters. Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardization and validation of in vitro techniques (especially large, organized validation efforts currently supported by US and EU regulatory agencies), and the theories supporting the development of in vitro methodologies. This second edition is a must-read for undergraduate and graduate toxicology students. Industrial and academic research centers will also find the text useful for establishing a toxicology testing laboratory.