Animal Cell Technology Developments Towards The 21st Century

Author : E.C. Beuvery,W.P. Zeijlemaker,J.B. Griffiths
Publisher : Springer Science & Business Media
Page : 1083 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401104371

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Animal Cell Technology: Developments towards the 21st Century by E.C. Beuvery,W.P. Zeijlemaker,J.B. Griffiths Pdf

Animal cell technology is a discipline of growing importance, which aims not merely at understanding structure, function and behaviour of differentiated animal cells, but especially at the development of their abilities useful for clinical application. Topics of interest in this regard include: viral vaccines, pharmaceutical proteins and novel applications such as gene therapy and organ culture. Undoubtedly, these Proceedings of the joint Meeting of the European Society for Animal Cell Technology and the Japanese Association for Animal Cell Technology (Veldhoven, The Netherlands, September 1994) review the most recent status of the field, and will be most valuable to anyone actively involved in the culture of animal cells and its applications. The contributions to this volume were strictly selected on the basis of quality and novelty of contents. Kluwer is honoured to be able to add this work to its strongly developing publication programme in cell and tissue culture, which now has its connections to all major Societies in this field worldwide. Audience: Cell biologists, biochemists, molecular biologists, immunologists, virologists and all other disciplines related to animal cell technology, working in an academic environment, as well as in (biotechnology or pharmaceutical) industry.

Author : R. E. Spier,J. B. Griffiths,C. Macdonald
Publisher : Butterworth-Heinemann
Page : 784 pages
File Size : 40,5 Mb
Release : 2013-10-02
Category : Science
ISBN : 9781483145075

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Animal Cell Technology by R. E. Spier,J. B. Griffiths,C. Macdonald Pdf

Animal Cell Technology: Developments, Processes and Products is a compilation of scientific papers presented at the 11th European Society for Animal Cell Technology (ESACT) Meeting, held in Brighton, United Kingdom. The book is a collection of various works of scientists, engineers, and other specialists from Europe and other parts of the world who are working with animal cells. The book’s aim is to communicate experiences and research findings on the development of cell systems. The research papers are grouped into 25 sections encompassing 145 chapters. Subjects covered range from cells and physiology engineering dealing with cell characterization, cell culture establishment, cloning, and cell engineering. Topics on culture media, ammonium detoxification, the effects of physical parameters on cell cultures, assays and monitoring systems, and bioreactor techniques are also covered. Discussions are likewise made on the products from animal cells in culture, virus removal, and DNA determination and characterization in relation to safety issues. The book will be useful for cell biologists, molecular biologists, biochemists, biochemical engineers, and students engaged in the study of animal cell cultures.

Author : Japanese Association for Animal Cell Technology
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 53,9 Mb
Release : 1999-08-31
Category : Medical
ISBN : 9780792358053

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Animal Cell Technology: Challenges for the 21st Century by Japanese Association for Animal Cell Technology Pdf

Animal cell technology aims to understand structures, functions, and behaviors of differentiated animal cells and to ascertain their abilities to be used in industrial and medical purposes. This volume gives readers a complete review of the present state of the art in Japan.

Author : Nigel Jenkins,Niall Barron,Paula Alves
Publisher : Springer Science & Business Media
Page : 756 pages
File Size : 47,7 Mb
Release : 2011-09-15
Category : Medical
ISBN : 940070884X

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Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 by Nigel Jenkins,Niall Barron,Paula Alves Pdf

The 21st ESACT conference was held in the beautiful surroundings of the CityWest Hotel resort in Dublin, Ireland. For the first time in ESACT history the number of participants exceeded 900: a sign of the ever increasing importance of this area. The conference commenced on Sunday June 5th with two sets of parallel workshops on the subjects listed below. An additional workshop was held on Monday lunchtime of the conferenceProcess Analytical Technology (PAT), Quality by Design (QbD) and other recent regulatory developments. 2. Innovative media products for the 21st century biopharmaceutical industry. 3. The impact of high titre media feed-streams on monoclonal antibody purification. 4. Advances in genomics and proteomics. 5. Stem Cell Technology: new developments and clinical applications.

Author : Otto-Wilhelm Merten,Pierre Perrin,Bryan Griffiths
Publisher : Springer Science & Business Media
Page : 708 pages
File Size : 47,5 Mb
Release : 2007-05-08
Category : Science
ISBN : 9780306468605

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New Developments and New Applications in Animal Cell Technology by Otto-Wilhelm Merten,Pierre Perrin,Bryan Griffiths Pdf

Animal cell technology is becoming an increasingly important part of biotechnology and many products are now used in human health care and for veterinary applications. However, there are many times more products actually in the developmental pipelines of the biotechnology industry, including various phases of clinical trials. The Proceedings of the 15th Meeting of the European Society for Animal Cell Technology (Tours, France, September 1997) presents the actual current state as well as New Developments and Applications in Animal Cell Technology for the benefit of society. These Proceedings represent both the current state and applications of animal cell technology and the way the technology is expanding into new areas to give a unique insight into new products and applications for human and animal health care.

Author : Michael Butler
Publisher : Garland Science
Page : 299 pages
File Size : 48,7 Mb
Release : 2004-08-02
Category : Medical
ISBN : 9781135325374

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Animal Cell Culture and Technology by Michael Butler Pdf

Animal cell culture is an important laboratory technique in the biological and medical sciences. It has become an essential tool for the study of most biochemical and physiological processes and the use of large-scale animal cell culture has become increasingly important to the commercial production of specific compounds for the pharmaceutical industry. This book describes the basic requirements for establishing and maintaining cell cultures both in the laboratory and in large-scale operations. Minimal background knowledge of the subject is assumed and therefore it will be a readable introduction to animal cell culture for undergraduates, graduates and experienced researchers. Reflecting the latest developments and trends in the field, the new topics include the latest theory of the biological clock of cell lines, the development of improved serum-free media formulations, the increased understanding of the importance and control of protein glycosylation, and the humanization of antibodies for therapeutic use.

Author : R.E. Spier,J.B. Griffiths
Publisher : Elsevier
Page : 846 pages
File Size : 40,5 Mb
Release : 2013-10-02
Category : Technology & Engineering
ISBN : 9781483145099

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Modern Approaches to Animal Cell Technology by R.E. Spier,J.B. Griffiths Pdf

Modern Approaches to Animal Cell Technology is a collection of papers presented at the 1987 joint European Society for Animal Cell Technology-OHOLO conference held in Tiberias, Israel. Contributors explore modern approaches to animal cell technology and discuss the construction of the animal cell substrate, the physiology of those cells in a bioreactor type of environment, and the ways in which different products can be made from animal cells in culture and tested. This book is comprised of 59 chapters divided into nine sections and begins by outlining the history of issues and decisions that were made regarding the acceptability of various cell substrates, along with the use of continuous cell lines in biotechnology. The next chapter explores the feasibility, reproducibility, and the sensitivity of the dot-blot filter hybridization test to detect minute amounts of residual cellular DNA. The reader is then introduced to cells and cell lines such as monoclonal antibodies; cell growth and development; physiology of cells; and the use of bioreactors for culturing animal cells. Downstream unit processes, vaccines, immune system products, and toxicity testing with animal cells are also considered. This monograph will be a valuable resource for animal-cell technologists, biotechnologists, and microbiologists.

Author : Kouji Ikura,Masaya Nagao,Seiji Masuda
Publisher : Unknown
Page : 472 pages
File Size : 46,9 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 9401741018

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Animal Cell Technology by Kouji Ikura,Masaya Nagao,Seiji Masuda Pdf

Author : Manuel J.T. Carrondo,Bryan Griffiths,José L.P. Moreira
Publisher : Springer Science & Business Media
Page : 816 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401154048

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Animal Cell Technology by Manuel J.T. Carrondo,Bryan Griffiths,José L.P. Moreira Pdf

Animal cell technology has undergone a rapid transformation over the last decade from a research tool and highly specialised technology to a central resource for innovation in pharmaceutical research and development. These proceedings of the 14th Meeting of the European Society for Animal Cell Technology (Vilamoura, Portugal, May 1996) bring up to date the historical perspective of animal cell technology for the benefit of society, `From Vaccines to Genetic Medicine', and will charter this vital technology for the years to come. Strong contributions are grouped in the traditional ESACT areas of 'Cell and Physiology Engineering' dealing with cell state, including genetics, and its environment, and 'Animal Cell Process Engineering' covering integration of bioreaction with bioseparation coupled with on-line monitoring to improve protein production and consistency. Extensive coverage of metabolic engineering on synthesis, folding, assembly, transiting and secretion is dealt with in the session on 'Recombinant Proteins: Biosynthesis and Bioprocessing'. Two traditional but expanding areas of animal cell technology relevance are highlighted in the broad sessions of 'Animal Cells as Tools for Discovery and Testing' and 'Animal Cell Vaccines: Present and Future'. Two sessions finally cover the more recent domains of animal cell technology work - 'Tissue Engineering and Biomedical Devices' and 'Cells and Vectors for Genetic Medicine' - where one can foresee a very bright future.

Author : Leda Castilho,Angela Moraes,Elisabeth Augusto,Mike Butler
Publisher : Taylor & Francis
Page : 506 pages
File Size : 46,6 Mb
Release : 2008-03-01
Category : Medical
ISBN : 9781134099726

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Animal Cell Technology by Leda Castilho,Angela Moraes,Elisabeth Augusto,Mike Butler Pdf

Animal Cell Technology: from Biopharmaceuticals to Gene Therapy provides a comprehensive insight into biological and engineering concepts related to mammalian and insect cell technology, as well as an overview of the applications of animal cell technology. Part 1 of the book covers the Fundamentals upon which this technology is based and covers the science underpinning the technology. Part 2 covers the Applications from the production of therapeutic proteins to gene therapy. The authors of the chapters are internationally-recognized in the field of animal cell culture research and have extensive experience in the areas covered in their respective chapters.

Author : European Society of Animal Cell Technology. General Meeting
Publisher : Springer Science & Business Media
Page : 684 pages
File Size : 42,9 Mb
Release : 2001-11-30
Category : Medical
ISBN : 1402002645

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Animal Cell Technology: From Target to Market by European Society of Animal Cell Technology. General Meeting Pdf

This book is the lasting product, a resource of up-to-date information in the scientific literature for the field of animal cell technology, as it was presented during a pleasant and stimulating meeting in Tylösand, Sweden, in June 2001. The title of the meeting, From Target to Market, indicates the usefulness of Animal Cell Technology during all steps in the pharmaceutical development process. Following the biotech products reaching the market, it shows an upward trend in the contribution of biotech products to total New Molecular Entity output in the nineties, which continued until 1996 when biotech represented 25% of the annual output. Since then the proportion has been decreasing. A perceived hurdle from a market perspective is that a protein per definition is biodegradable and thus requires intravenous, or for some drugs subcutaneous administration. New promising administration technologies such as pulmonary delivery were highlighted at this meeting. The emphasis on project selection prior to entry in the development phase has triggered a portfolio management using more extensive preclinical data before a development decision is taken. Animal cells have become a very important tool in the drug discovery process. The next generation of products will evolve from applications such as gene therapy, novel vaccines, cell therapy, and gene regulation. Animal cell technology has a major role to play in the post-sequence era.

Author : T. Kobayashi,Y. Kitagawa,K. Okumura
Publisher : Springer Science & Business Media
Page : 578 pages
File Size : 49,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401108485

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Animal Cell Technology: Basic & Applied Aspects by T. Kobayashi,Y. Kitagawa,K. Okumura Pdf

Animal cell technology is a growing discipline of cell biology which aims to understand the structure, function and behaviour of differentiated animal cells, and especially the development of such abilities as are useful for industrial purposes. These developments range from clonal expansion of differentiated cells with useful abilities, to optimization of cell culture on industrial scale and modulation of the cells' abilities to produce drugs and monoclonal antibodies. The sixth volume in this series gives a complete review of today's state of the art in Japan, a country where this field is especially well advanced. It will be of interest to cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to animal cell culture, working in the academic environment as well as in (biotechnology or pharmaceutical) industry.

Author : Sadettin Ozturk,Wei-Shou Hu
Publisher : CRC Press
Page : 776 pages
File Size : 43,8 Mb
Release : 2005-08-30
Category : Medical
ISBN : 9780849351068

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Cell Culture Technology for Pharmaceutical and Cell-Based Therapies by Sadettin Ozturk,Wei-Shou Hu Pdf

Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology devel

Author : R. Ian Freshney
Publisher : Wiley-Liss
Page : 696 pages
File Size : 54,9 Mb
Release : 2005-07-29
Category : Science
ISBN : 0471453293

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Culture of Animal Cells by R. Ian Freshney Pdf

The most complete resource on the techniques, equipment,principles, and practices of animal cell culture Since publication of the previous edition of this benchmark text, numerous groundbreaking advances have occurred in stem cell research, cloning, tissue engineering, and in vitro toxicity testing. These and other developments have been incorporated into this fully revised and expanded Fifth Edition of Culture of Animal Cells. In addition, to answer the needs of the exponential increase in newcomers to cell culture, particularly in the biopharmaceutical industry, a completely new chapter on training in cell culture technology has been introduced. The most complete resource on the techniques, equipment, principles, and practices of animal cell culture, this text offers a complete background related to growth of animal cells in culture. Beginning with laboratory design, safety, validation and bioethics, then continuing with preparation of media, primary culture and cell lines, through to characterization and authentication, contamination, specialized techniques, and troubleshooting, the coverage includes: * An all-new section of training exercises, separated into basic, intermediate, and advanced procedures, cross-referenced to the relevant protocols * New coverage of stem cells, bioethics, validation, cloning, cell signaling, in vitro toxicity testing, and tissue engineering * An expanded full-color atlas section, with images of primary culture, cell lines, subculture, differentiation, cancer cells and transformation, three-dimensional culture, contamination, and specialized equipment * Enhanced treatment of troubleshooting, with full cross-referencing to the relevant protocols and sections of text * Fully updated references * The clearest, most consistent presentation of step-by-step protocols available * Numerous diagrams, photographs, tables, and charts * Detailed and up-to-date information on reagent preparation and sourcing of materials and equipment, including a fully updated list of suppliers and other resources with Web sites Indispensable for clinical and biopharmaceutical researchers and scientists, students, trainees, and technicians, this landmark text presents the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells.

Author : European Society of Animal Cell Technology. General Meeting,Alain Bernard
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 48,5 Mb
Release : 1999
Category : Medical
ISBN : 9780792360759

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Animal Cell Technology: Products from Cells, Cells as Products by European Society of Animal Cell Technology. General Meeting,Alain Bernard Pdf

This book contains, in the form of concise papers of limited length, the proceedings of the 16th ESACT meeting that was held in Lugano, Switzerland, in April 1999. We hope it will become a useful resource of the most up-to-date information in animal cell technology, at least until the next meeting in 2001. Classical approaches for the use of animal cells (for example, production of virus vaccines) remain an important technology. However, it appears that major technological advances and major growth are occurring in other areas. Most importantly, protein production on the basis of recombinant DNA molecules transferred into animal cells appears to be an ever-increasing field of interest and innovation. Increasingly animal cells are being used as substrates for the study of gene activation and repression, and also for the more rapid production of small and moderate quantities of interesting proteins. Tissue engineering, somatic gene/cell therapy, organ-replacement technologies, and cell-based bio-sensors all contribute to a considerable widening of interest and research activity, based on animal cell technology.