Author : G. S. Gupta
Publisher : Unknown
Page : 1220 pages
File Size : 53,5 Mb
Release : 2013
Category : Electronic
ISBN : 1283849585
Animal Lectins
G. S. Gupta
Animal Lectins Form Function And Clinical Applications
Animal Lectins Form Function And Clinical Applications Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Animal Lectins Form Function And Clinical Applications book. This book definitely worth reading, it is an incredibly well-written.
Animal Lectins: Form, Function and Clinical Applications
G. S. Gupta
Author : G. S. Gupta
Publisher : Springer
Page : 0 pages
File Size : 44,9 Mb
Release : 2016-08-23
Category : Science
ISBN : 3709148375
Animal Lectins: Form, Function and Clinical Applications by G. S. Gupta Pdf
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular distribution, molecular structure, gene organization, possible functions, clinical applications, lectin-ligand interactions and their intervention for therapeutic purposes are provided. The recently discovered C-type lectins as well as further novel super-families of this group of molecules are described in detail. Furthermore, the clinical significance of animal lectins in inflammatory diseases, defects of immune defense and autoimmunity are described and their application as drugs and therapeutic targets is discussed. With the increasing interest in lectins in biomedical research and their therapeutic applications, this book on animal lectins and associated proteins is a must have for researchers in the area.
Animal Lectins
Gerardo R. Vasta PhD,Hafiz Ahmed PhD
Author : Gerardo R. Vasta PhD,Hafiz Ahmed PhD
Publisher : CRC Press
Page : 596 pages
File Size : 41,8 Mb
Release : 2008-10-09
Category : Medical
ISBN : 9781420006971
Animal Lectins by Gerardo R. Vasta PhD,Hafiz Ahmed PhD Pdf
Introduces Groundbreaking Approaches for Assessing Lectin Function Lectins and their ligands are under quite a heavy microscope due to their potential applications to pharmacology, immunology, cancer therapy, and agriculture. With growing interest in the glycobiology field, the body of research related to lectin roles has grown at an explosive rate
Animal Lectins: Form, Function and Clinical Applications
G. S. Gupta
Author : G. S. Gupta
Publisher : Springer Science & Business Media
Page : 1108 pages
File Size : 45,7 Mb
Release : 2012-11-13
Category : Science
ISBN : 9783709110652
Animal Lectins: Form, Function and Clinical Applications by G. S. Gupta Pdf
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular distribution, molecular structure, gene organization, possible functions, clinical applications, lectin-ligand interactions and their intervention for therapeutic purposes are provided. The recently discovered C-type lectins as well as further novel super-families of this group of molecules are described in detail. Furthermore, the clinical significance of animal lectins in inflammatory diseases, defects of immune defense and autoimmunity are described and their application as drugs and therapeutic targets is discussed. With the increasing interest in lectins in biomedical research and their therapeutic applications, this book on animal lectins and associated proteins is a must have for researchers in the area.
Essentials of Glycobiology
Ajit Varki,Maarten J. Chrispeels
Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 51,9 Mb
Release : 1999
Category : Medical
ISBN : 0879696818
Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Lectins
Preetham Elumalai,Sreeja Lakshmi
Author : Preetham Elumalai,Sreeja Lakshmi
Publisher : Springer Nature
Page : 306 pages
File Size : 52,7 Mb
Release : 2022-03-09
Category : Science
ISBN : 9789811674624
Lectins by Preetham Elumalai,Sreeja Lakshmi Pdf
This book reviews the relationship between receptors, carbohydrate moieties, and pathogenic surfaces and lectins’ pathophysiology of immune responses and examines the mechanisms of action of the molecules for the treatment potentials. Increasing evidence has suggested that lectin-carbohydrate interactions perform important roles in various regulations of immune responses, but much remains to be learned about these crucial properties and their interplay with other molecules. In addition, a better understanding of the structural and functional properties of lectin and the activated immune response will be of critical importance for the development of new diagnostic tools and therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the various lectin types from animal and plant as well as microbial or marine lectins, and this wide range of molecular knowledge directs us to various diseases, including infectious diseases and cancer. In presenting state-of-the-art knowledge on the interactions between lectin and its interactions,the book will help to pave the way for the development of novel targets for the prevention and treatment of many disorders.
Handbook of Clinical Nanomedicine
Raj Bawa,Gerald F. Audette,Israel Rubinstein
Author : Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher : CRC Press
Page : 1708 pages
File Size : 55,9 Mb
Release : 2016-02-22
Category : Medical
ISBN : 9789814669214
Handbook of Clinical Nanomedicine by Raj Bawa,Gerald F. Audette,Israel Rubinstein Pdf
This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosim
Plant Lectins
A. Pusztai
Author : A. Pusztai
Publisher : Cambridge University Press
Page : 276 pages
File Size : 50,5 Mb
Release : 1991
Category : Medical
ISBN : 9780521328241
Plant Lectins by A. Pusztai Pdf
This volume surveys the chemistry, biochemistry, biosynthesis, metabolism and pharmacological properties of lectins. Lectins, which are most commonly found in plants, are widespread natural products with striking biological activities. Their specific ability to recognise and bind to simple or complex saccharides facilitates their role as effective information protein molecules. As agents of cell-to-cell recognition, lectins promote symbiosis between plants and specific nitrogen-fixing soil bacteria. As natural defensive molecules, they can protect plants against predators such as bacteria, fungi and insects. As part of our diet, lectins are powerful exogenous growth factors in the small intestine and influence our health, the digestive function and the bacterial ecology of the alimentary tract. Lectins are also important research tools in preparative biochemistry and cell science.
Carbohydrate Recognition
Binghe Wang,Geert-Jan Boons
Author : Binghe Wang,Geert-Jan Boons
Publisher : John Wiley & Sons
Page : 448 pages
File Size : 45,6 Mb
Release : 2011-09-09
Category : Medical
ISBN : 9781118017579
Carbohydrate Recognition by Binghe Wang,Geert-Jan Boons Pdf
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Aquatic Lectins
Preetham Elumalai,Baskaralingam Vaseeharan,Sreeja Lakshmi
Author : Preetham Elumalai,Baskaralingam Vaseeharan,Sreeja Lakshmi
Publisher : Springer Nature
Page : 389 pages
File Size : 50,6 Mb
Release : 2022-05-03
Category : Science
ISBN : 9789811904325
Aquatic Lectins by Preetham Elumalai,Baskaralingam Vaseeharan,Sreeja Lakshmi Pdf
This book provides the latest information on fish lectins from the perspective of inflammation and presents new ideas on the complicated mechanisms of lectin biochemistry and associated interactions. Key features include discussion of mechanisms recently identified to be involving lectin family types, presentation of the latest evidence regarding the molecular approaches in fish lectins, and thorough explanation of the concept of antimicrobial and immunological roles and current understanding of the significance of its disease resistance related studies. Gene expression studies is another important element of the book, and it is proposed that gene editing technology provides gaining attention in the biological role of fish lectin research. Examples of the many lastest molecular approaches, applications and future perspectives in fish lectin specific topics covered in this book include the information right from the basics to the advancements in this area. The book will be a valuable update and resource for both experienced and younger researchers working in the field of lectins and immunology.
Multivalency
Jurriaan Huskens,Leonard J. Prins,Rainer Haag,Bart Jan Ravoo
Author : Jurriaan Huskens,Leonard J. Prins,Rainer Haag,Bart Jan Ravoo
Publisher : John Wiley & Sons
Page : 434 pages
File Size : 41,6 Mb
Release : 2018-02-05
Category : Science
ISBN : 9781119143468
Multivalency by Jurriaan Huskens,Leonard J. Prins,Rainer Haag,Bart Jan Ravoo Pdf
Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.
Galectins in Cancer and Translational Medicine
Armando Bartolazzi
Author : Armando Bartolazzi
Publisher : MDPI
Page : 351 pages
File Size : 54,8 Mb
Release : 2018-11-29
Category : Electronic books
ISBN : 9783038974086
Galectins in Cancer and Translational Medicine by Armando Bartolazzi Pdf
In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell "glycome" in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical for cell physiology and for cancer as well. Galectins (also worded S-type lectins) are an evolutionarily conserved family of endogenous lectins, which bind carbohydrates with high specificity. These molecules, which can be found both intracellularly and in the extracellular milieu, are functionally active in converting glycan-containing information into cell biological programs. This fashionable mechanism of signal transduction plays a relevant role in regulating several biological functions, including RNA splicing, gene transcription, cell migration and differentiation, apoptosis, immune response, and tumor growth and progression. It is not surprising, indeed, that a large number of studies on galectin-glycan interactions and galectins expression and function in human diseases have been published in the recent literature, spanning from immunology to cardiovascular medicine, from diagnostic Pathology to nuclear medicine. The aim of this Special Issue of IJMS is to collect selected contributions in the field reporting data, concepts, and new ideas, which have the potential to be translated in a clinical setting in the near future, in order to improve the diagnosis and treatment of cancer and other relevant human diseases.
Phytochemistry, 3-Volume Set
Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Udedi Chidi,Shashank Kumar,Jaya Vikas Kurhekar,Nadia Sharif
Author : Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Udedi Chidi,Shashank Kumar,Jaya Vikas Kurhekar,Nadia Sharif
Publisher : CRC Press
Page : 1806 pages
File Size : 43,5 Mb
Release : 2022-05-30
Category : Health & Fitness
ISBN : 9780429760488
Phytochemistry, 3-Volume Set by Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Udedi Chidi,Shashank Kumar,Jaya Vikas Kurhekar,Nadia Sharif Pdf
The 3-volume set, Phytochemistry, covers a wide selection of topics in phytochemistry and provides a wealth of information on the fundamentals, new applications, methods and modern analytical techniques, state-of-the-art approaches, and computational techniques. With chapters from professional specialists in their fields from around the world, the volumes deliver a comprehensive coverage of phytochemistry. Phytochemistry is a multidisciplinary field, so this book will appeal to students in both upper-level students, faculty, researchers, and industry professionals in a number of fields, including biological science, biochemistry, pharmacy, food and medicinal chemistry, systematic botany and taxonomy, ethnobotany, conservation biology, plant genetic and metabolomics, evolutionary sciences, and plant pathology.
Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation
Florence E. Roufosse,Mats W. Johansson
Author : Florence E. Roufosse,Mats W. Johansson
Publisher : Frontiers Media SA
Page : 279 pages
File Size : 53,5 Mb
Release : 2018-12-06
Category : Electronic
ISBN : 9782889456246
Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation by Florence E. Roufosse,Mats W. Johansson Pdf
With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much remains to be known about eosinophil biology in vivo, and have nurtured profuse research both on basic eosinophil biology and on pathogenic disease mechanisms, in order to better delineate the most meaningful targets for innovative therapeutic strategies. On one hand, variable degrees of eosinophil depletion observed in some compartments during IL-5-targeted treatment indicate that certain eosinophil subsets may not rely on this cytokine and/or that other important pro-eosinophilic mediators and signaling pathways are operative in vivo. On the other hand, it is increasingly clear that disorders involving eosinophils such as asthma are the final outcome of complex interactions between diverse cell types and mediators, beyond eosinophils and IL-5. These include type 2 helper T (Th2) cells and innate lymphoid cells, mast cells, and a variety of factors that either activate eosinophils or are released by them. Although a considerable amount of research has focused on asthma because it is a common condition and because management of severe asthma remains a major challenge, several rare eosinophilic disorders with more homogenous features have proven to be extremely useful models to reach a better understanding of the involvement of eosinophils in tissue damage and dysfunction, and of the micro-environmental interactions operating within the complex network of eosinophilic inflammation. Unraveling this interplay has resulted in advances in the development of molecular tools to detect disease subsets and to monitor therapeutic responses, and in identification of promising new therapeutic targets. This Research Topic dedicated to eosinophilic conditions covers aspects of the biology of eosinophils and closely related cells of particular relevance for drug development, reports on translational research investigating pathogenic mechanisms of specific eosinophilic disorders in humans that will likely result in significant changes in the way patients are managed, and presents an overview of the current advancement of targeted drug development for these conditions, with a special focus on asthma.
Phytochemistry
Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Chidi Udedi,Shashank Kumar
Author : Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Chidi Udedi,Shashank Kumar
Publisher : CRC Press
Page : 658 pages
File Size : 53,6 Mb
Release : 2018-12-12
Category : Health & Fitness
ISBN : 9780429760334
Phytochemistry by Chukwuebuka Egbuna,Jonathan Chinenye Ifemeje,Stanley Chidi Udedi,Shashank Kumar Pdf
This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.