Antibacterial Agents

Author : Rosaleen Anderson,Paul W. Groundwater,Adam Todd,Alan Worsley
Publisher : John Wiley & Sons
Page : 379 pages
File Size : 41,6 Mb
Release : 2012-05-30
Category : Science
ISBN : 9781118325445

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Antibacterial Agents by Rosaleen Anderson,Paul W. Groundwater,Adam Todd,Alan Worsley Pdf

Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

Author : National Research Council,Division on Earth and Life Studies,Division of Medical Sciences,Commission on Life Sciences,Committee to Study the Human Health Effects of Subtherapeutic Antibiotic Use in Animal Feeds
Publisher : National Academies Press
Page : 393 pages
File Size : 53,8 Mb
Release : 1980-02-01
Category : Medical
ISBN : 9780309030441

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The Effects on Human Health of Subtherapeutic Use of Antimicrobials in Animal Feeds by National Research Council,Division on Earth and Life Studies,Division of Medical Sciences,Commission on Life Sciences,Committee to Study the Human Health Effects of Subtherapeutic Antibiotic Use in Animal Feeds Pdf

Author : S.L. Dax
Publisher : Springer Science & Business Media
Page : 409 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400900974

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Antibacterial Chemotherapeutic Agents by S.L. Dax Pdf

Over the past 50 years a wide variety of antibacterial substances have been discovered and synthesised, and their use in treating bacterial infection has been spectacularly successful. Today there are several general classes of antibacterial drugs, each having a well established set of uses, and together they form the mainstay of modern antibacterial chemotherapy. In search for new and improved agents, the pharmaceutical researcher needs to be well informed on many topics, including existing agents, their modes of action and pharmacology, and possible synthetic approaches. In this new book the author has brought together a wide range of information on the principal classes of antibacterial agents, and he covers, for each group, their history, mode of action, key structural features, synthesis and bacterial resistance. The result is a compact and concise overview of these very important classes of antibacterial agents.

Author : Ranjith Kumavath
Publisher : BoD – Books on Demand
Page : 140 pages
File Size : 51,6 Mb
Release : 2017-05-31
Category : Science
ISBN : 9789535131991

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Antibacterial Agents by Ranjith Kumavath Pdf

New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Author : André Bryskier
Publisher : Amer Society for Microbiology
Page : 1426 pages
File Size : 55,6 Mb
Release : 2005
Category : Medical
ISBN : 1555812376

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Antimicrobial Agents by André Bryskier Pdf

Comprehensively covers the history, chemistry, synthesis, mechanisms of action, pharmacology, and efficacy of all antimicrobial agents. Serves as a reference source for physicians, microbiologists, chemists, pharmacologists, research scientists, and all others involved in antimicrobial research and development.

Author : Varaprasad Bobbarala
Publisher : BoD – Books on Demand
Page : 358 pages
File Size : 43,7 Mb
Release : 2012-09-19
Category : Science
ISBN : 9789535107248

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A Search for Antibacterial Agents by Varaprasad Bobbarala Pdf

This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Author : Oreste A. Mascaretti
Publisher : Unknown
Page : 436 pages
File Size : 44,6 Mb
Release : 2003
Category : Medical
ISBN : UOM:39015056843009

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Bacteria Versus Antibacterial Agents by Oreste A. Mascaretti Pdf

A clear, concise, introductory text on antibacterial agents. - Reviews the basics of bacterial structure and function, and describes the basis for understanding mechanisms of antibacterial action, as well as the mechanisms developed by bacteria to overcome the action of antibacterial agents. - Covers the characteristic features of bacterial pathogenicity, the genetic basis of resistance to antibacterial drugs, the biochemical mechanisms of action of antibacterial drugs, how antibacterial drugs reach their targets in gram-positive and gram-negative bacteria, and the wide range of human immune responses against bacterial infections. - Examines advances in research and development of new classes of antibacterial drugs.

Author : Alan R. Hauser
Publisher : Wolters kluwer india Pvt Ltd
Page : 128 pages
File Size : 42,5 Mb
Release : 2020-04-01
Category : Medical
ISBN : 9789389702651

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Antibiotic Basics for Clinicians by Alan R. Hauser Pdf

Antibiotic Basics for Clinicians, South Asian Edition, simplifies the antibiotic selection process for the clinicians with up-to-date information on the latest and most clinically relevant antibacterial medications. This time-saving resource helps medical students master the rationale behind antibiotic selection for common

Author : Halldor Thormar
Publisher : John Wiley & Sons
Page : 341 pages
File Size : 44,7 Mb
Release : 2010-12-28
Category : Science
ISBN : 9780470976678

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Lipids and Essential Oils as Antimicrobial Agents by Halldor Thormar Pdf

Lipids and essential oils have strong antimicrobial properties — they kill or inhibit the growth of microbes such as bacteria, fungi, or viruses. They are being studied for use in the prevention and treatment of infections, as potential disinfectants, and for their preservative and antimicrobial properties when formulated as pharmaceuticals, in food products, and in cosmetics. Lipids and Essential Oils as Antimicrobial Agents is a comprehensive review of the scientific knowledge in this field. International experts provide summaries on: the chemical and biological properties of lipids and essential oils use of lipids and essential oils in pharmaceuticals, cosmetics and health foods antimicrobial effects of lipids in vivo and in vitro antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils Lipids and Essential Oils as Antimicrobial Agents is an essential guide to this important topic for researchers and advanced students in academia and research working in pharmaceutical, cosmetic and food sciences, biochemistry and natural products chemistry, microbiology; and for health care scientists and professionals working in the fields of public health and infectious diseases. It will also be of interest to anyone concerned about health issues and particularly to those who are conscious of the benefits of health food and natural products.

Author : Roger Finch,Peter Davey,Mark H. Wilcox,William Irving
Publisher : OUP Oxford
Page : 409 pages
File Size : 44,8 Mb
Release : 2012-01-05
Category : Medical
ISBN : 9780191628658

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Antimicrobial Chemotherapy by Roger Finch,Peter Davey,Mark H. Wilcox,William Irving Pdf

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Author : John Mann,M. James C. Crabbe
Publisher : University Science Books
Page : 92 pages
File Size : 47,8 Mb
Release : 1996
Category : Antibiotics
ISBN : UVA:X004126358

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Bacteria and Antibacterial Agents by John Mann,M. James C. Crabbe Pdf

Author : Trevor John Franklin,G. A. Snow
Publisher : Springer
Page : 235 pages
File Size : 49,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489934123

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Biochemistry of Antimicrobial Action by Trevor John Franklin,G. A. Snow Pdf

The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division. The use of antimicrobial agents as highly specific inhibitors has in turn substantially assisted the investigation of complex biochemical processes. The literature in this field is so extensive however, that we considered an attempt should be made to draw together in an introductory book the more significant studies of recent years. This book, which is in fact based on lecture courses given by us to undergraduates at Liverpool and Manchester Universities, is therefore intended as an introduction to the biochemistry of antimicrobial action for advanced students in many disciplines. We hope that it may also be useful to established scientists who are new to this area of research. The book is concerned with a discussion of medically important antimicrobial compounds and also a number of agents that, although having no medical uses, have proved invaluable as research tools in biochemistry. Our aim has been to present the available information in a simple and readable way, emphasizing the established facts rather than more controversial material. Whenever possible, however, we have indicated the gaps in the present knowledge of the subject where further information is required.

Author : Varaprasad Bobbarala
Publisher : BoD – Books on Demand
Page : 358 pages
File Size : 42,9 Mb
Release : 2012-09-19
Category : Science
ISBN : 9789535107248

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A Search for Antibacterial Agents by Varaprasad Bobbarala Pdf

This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Author : Bruce K. Rubin,Jun Tamaoki
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 44,7 Mb
Release : 2006-03-30
Category : Medical
ISBN : 9783764373108

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Antibiotics as Anti-Inflammatory and Immunomodulatory Agents by Bruce K. Rubin,Jun Tamaoki Pdf

Although the potential for immunomodulation has been recognized for many years there has been an explosion of data in this field with relevance especially to the treatment of chronic airway diseases. Most of the work in this field has been conducted by Japanese investigators but in the last decade there has been a body of work outside of Japan that supports and enhances these findings. The book covers basic research like effects on bacteria, anti-inflammatory and mucoregulatory effects, but also clinical results with up-to-date information for the use of such medications to potentially treat diseases as diverse as chronic airway diseases, arthritis, inflammatory bowel disease, and cancer. The volume is intended for pulmonary physicians, researchers in inflammation research, and pharmaceutical companies interested in the development of such agents. It provides background information for the clinician as well as in depth exploration of cutting edge science.

Author : Richard Schwalbe,Lynn Steele-Moore,Avery C. Goodwin
Publisher : CRC Press
Page : 430 pages
File Size : 53,7 Mb
Release : 2007-05-22
Category : Medical
ISBN : 9781420014495

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Antimicrobial Susceptibility Testing Protocols by Richard Schwalbe,Lynn Steele-Moore,Avery C. Goodwin Pdf

The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and