Antimicrobial Photodynamic Therapy

Author : Natalia Mayumi Inada,Hilde Harb Buzzá,Kate Cristina Blanco,Lucas Danilo Dias,Giulia Kassab
Publisher : BoD – Books on Demand
Page : 243 pages
File Size : 48,5 Mb
Release : 2021-05-05
Category : Science
ISBN : 9781839680601

Get Book

Photodynamic Therapy by Natalia Mayumi Inada,Hilde Harb Buzzá,Kate Cristina Blanco,Lucas Danilo Dias,Giulia Kassab Pdf

Today, in the face of resistant microorganisms, aggressive cancers unresponsive to conventional treatments, and the COVID-19 pandemic, the need for advanced and innovative protocols for combating and treating disease is paramount. This book presents basic concepts of photodynamic therapy along with data from clinical research on its use in treating oncologic and other diseases. It also presents innovative strategies in photodynamic therapy, including information on polymer nanoparticles. This book was prepared with great care and by many valuable hands so that we can expand the dissemination of Photodynamic Therapy, as well as motivate for new research.

Author : Siddhardha Busi,Ram Prasad
Publisher : CRC Press
Page : 377 pages
File Size : 42,7 Mb
Release : 2023-08-22
Category : Medical
ISBN : 9781000925340

Get Book

Antimicrobial Photodynamic Therapy by Siddhardha Busi,Ram Prasad Pdf

Antimicrobial Photodynamic Therapy: Concepts and Applications explores the novel antimicrobial therapeutic technique. As the world searches for new, efficient modalities for fighting microorganisms, this book offers a complete understanding of the concept, and knowledge about the emerging technique ‘antimicrobial photodynamic therapy’ (aPDT) for the scientific communities and budding researchers. The book aligns concepts, significance, and applications of the technique systematically. Chapters in the book cover microorganisms, pathogenesis, conventional treatment methods, and significance of new treatment approaches to the concept of antimicrobial photodynamic therapy. The authors describe the mechanism behind it, with applications and examples from research studies. The book discusses photosensitisers in detail, with one chapter emphasising natural photosensitisers. Use of nanostructures in the antimicrobial photodynamic therapy is elaborated on, and we conclude with a well-explored application of the therapeutic technique in dentistry. Features: Efficiently covers the topic in detail with scientifically proven examples. Applications of the therapeutic approach are well discussed, and readers can learn about the research gaps, challenges, and future of the technique. Starts from basics, enabling readers to understand why the approach is relevant and important for study. Simplistic elucidated concepts and applications make it accessible at all levels.

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 40,9 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

Get Book

Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Author : Michael R Hamblin,Giulio Jori
Publisher : Royal Society of Chemistry
Page : 450 pages
File Size : 55,5 Mb
Release : 2011-06-06
Category : Science
ISBN : 9781849733083

Get Book

Photodynamic Inactivation of Microbial Pathogens by Michael R Hamblin,Giulio Jori Pdf

Photodynamic therapy (PDT) was discovered over one hundred years ago after observing the death of microorganisms upon exposure to dyes and light. It is the combination of non-toxic dyes and harmless visible light that, in the presence of oxygen, produce highly toxic reactive species. The principal medical application during the last century was in cancer therapy but, in these days of rising antibiotic resistance, PDT shows increasing promise as an alternative approach to treating infections. PDT has also been used in blood product sterilization, peridontology, acne reduction, and the treatment of viral lesions such as those caused by human papilloma virus. It may also have potential as an environmentally friendly pesticide. This is the first and only book to comprehensively cover the use of light and photosensitising agents for controlling microbial pathogens. It provides a comprehensive and up-to-date coverage of an emerging field. There are several chapters on the design of antimicrobial photosensitizers, their use to kill pathogenic organisms and their success in treating infections in animal models. It has long been known that gram-positive bacteria are highly susceptible to photoinactivation but the book also discusses means of widening the range of microorganisms that can be tackled by PDT. Edited by two pioneers in the application of PDT to medical and environmental issues, this book covers the basic science, translational research in animals, and the clinical applications in various medical specialities. It represents an indispensable resource for microbiologists and infectious disease doctors as well as dentists, dermatologists, gastroenterologists and transfusion specialists.

Author : L F de Freitas
Publisher : Myprint
Page : 88 pages
File Size : 52,7 Mb
Release : 2016-04-14
Category : Electronic
ISBN : 1681747391

Get Book

Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by L F de Freitas Pdf

Author : Yohei Tanaka
Publisher : BoD – Books on Demand
Page : 264 pages
File Size : 40,6 Mb
Release : 2017-05-17
Category : Medical
ISBN : 9789535131557

Get Book

Photomedicine by Yohei Tanaka Pdf

Photomedicine is one of the most inspiring and interdisciplinary fields in medicine that involves the research and application of photobiology with respect to health and disease. Photomedicine has contributed to the clinical practice of a variety of medical fields, including dermatology, surgery, radiology, diagnostics, cardiology, and anticancer therapy. Furthermore, expansion of its scope and contribution can be expected. This book covers a wide range of aspects and issues related to photomedicine, which brings together researchers from many countries. These include the basic science of photodynamic therapy, clinical applications in various kinds of medical fields, photochemotherapy, laser therapy for musculoskeletal pain, intense pulsed light therapy for photorejuvenation, biological function of low-level laser therapy, and photobiology for skin rejuvenation. Not only will this be beneficial for readers, but it will also contribute to scientists making further breakthroughs in photomedicine.

Author : Lucas F. de Freitas
Publisher : Unknown
Page : 128 pages
File Size : 48,5 Mb
Release : 2016
Category : SCIENCE
ISBN : 1681741199

Get Book

Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by Lucas F. de Freitas Pdf

This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Author : Fábio Parra Sellera,Cristiane Lassálvia Nascimento,Martha Simões Ribeiro
Publisher : Springer
Page : 228 pages
File Size : 48,9 Mb
Release : 2017-02-27
Category : Medical
ISBN : 9783319450070

Get Book

Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice by Fábio Parra Sellera,Cristiane Lassálvia Nascimento,Martha Simões Ribeiro Pdf

This pioneering book offers an introduction to photodynamic therapy, a promising new approach in the treatment of complex diseases like cancer and microbial infections in animals. Addressing all aspects, ranging from basics to clinical practice, it presents the history and fundamentals of photodynamic therapy for non-experts. It includes a collection of basic and clinical studies in cancer and infectious diseases, as well as illustrations of successful treatment procedures and future perspectives and innovative applications involving nanotechnology and advanced drug delivery. This valuable resource offers readers insights into how the therapy works and how to apply it effectively in daily practice.

Author : Lucas F de Freitas,Michael R Hamblin
Publisher : Morgan & Claypool Publishers
Page : 105 pages
File Size : 43,7 Mb
Release : 2016-04-01
Category : Science
ISBN : 9781681740553

Get Book

Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by Lucas F de Freitas,Michael R Hamblin Pdf

This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Author : Herwig Kostron,Tayyaba Hasan
Publisher : Royal Society of Chemistry
Page : 680 pages
File Size : 43,7 Mb
Release : 2016
Category : Science
ISBN : 9781782624516

Get Book

Photodynamic Medicine by Herwig Kostron,Tayyaba Hasan Pdf

Comprehensive Series in Photochemical and Photobiological Sciences. Photodynamic therapy (PDT) is increasingly being used amongst health practitioners in combating a variety of disease. This book reviews the current state of development of PDT, and also presents the foreseeable advancements of the field in the next decade. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find this book an invaluable source of information. Chapters are drawn from research discusses at the 10th International Symposium on Photodynamic Therapy and Photodiagnosis in Clinical Practice in Brixen and are written and edited by leaders in the field. Mirroring the philosophy of that meeting, this book contains an informative balance of the basic sciences and clinical applications of PDT. Following an introduction to PDT, its history, and how techniques have developed, chapter serve as a practical guide for practitioners, covering topics such as sensitizer dosage and light dosage, and examples of relevant studies. The text goes further tp explore areas outside the medical field, such as the impact of PDT on society and the environment, and the economics of therapies. This book is dedicated to the memory of Professor Giulio Jori, and expert in this field, who sadly passed away on the 23rd December 2014.

Author : Michael R Hamblin,Giulio Jori
Publisher : Royal Society of Chemistry
Page : 451 pages
File Size : 55,7 Mb
Release : 2015-11-09
Category : Science
ISBN : 9781782626060

Get Book

Photodynamic Inactivation of Microbial Pathogens by Michael R Hamblin,Giulio Jori Pdf

Photodynamic therapy (PDT) was discovered over one hundred years ago after observing the death of microorganisms upon exposure to dyes and light. It is the combination of non-toxic dyes and harmless visible light that, in the presence of oxygen, produce highly toxic reactive species. The principal medical application during the last century was in cancer therapy but, in these days of rising antibiotic resistance, PDT shows increasing promise as an alternative approach to treating infections. PDT has also been used in blood product sterilization, peridontology, acne reduction, and the treatment of viral lesions such as those caused by human papilloma virus. It may also have potential as an environmentally friendly pesticide. This is the first and only book to comprehensively cover the use of light and photosensitising agents for controlling microbial pathogens. It provides a comprehensive and up-to-date coverage of an emerging field. There are several chapters on the design of antimicrobial photosensitizers, their use to kill pathogenic organisms and their success in treating infections in animal models. It has long been known that gram-positive bacteria are highly susceptible to photoinactivation but the book also discusses means of widening the range of microorganisms that can be tackled by PDT. Edited by two pioneers in the application of PDT to medical and environmental issues, this book covers the basic science, translational research in animals, and the clinical applications in various medical specialities. It represents an indispensable resource for microbiologists and infectious disease doctors as well as dentists, dermatologists, gastroenterologists and transfusion specialists.

Author : Sandile Phinda Songca,Oluwatobi Oluwafemi
Publisher : Royal Society of Chemistry
Page : 360 pages
File Size : 44,6 Mb
Release : 2023-11-01
Category : Science
ISBN : 9781837670550

Get Book

Combination Therapies Involving Photodynamic Therapy by Sandile Phinda Songca,Oluwatobi Oluwafemi Pdf

Combination Therapies Involving Photodynamic Therapy reviews the current state of development of PDT and presents the foreseeable advancements of combination approaches to therapeutic strategies.

Author : Krishnan Anand,Muthupandian Saravanan,Balakumar Chandrasekaran,Suvardhan Kanchi,Sarojini Jeeva Panchu,Quan-Sheng Chen
Publisher : Elsevier
Page : 610 pages
File Size : 43,7 Mb
Release : 2021-03-19
Category : Technology & Engineering
ISBN : 9780128210130

Get Book

Handbook on Nanobiomaterials for Therapeutics and Diagnostic Applications by Krishnan Anand,Muthupandian Saravanan,Balakumar Chandrasekaran,Suvardhan Kanchi,Sarojini Jeeva Panchu,Quan-Sheng Chen Pdf

Handbook of Nano-biomaterials for Therapeutics and Diagnostic Applications covers in-depth topics on nano-biomaterials and nano drug delivery systems (biosensors and bioimaging) involving polymer nanocomposites, metal nanocomposites, and other carbon family fibers and proteins. The book covers the current application of tiny machines or nanodevices and their use as early detection systems for life threatening diseases, giving detailed literature on the development of nanodevices, their use as diagnostic tools, and their present trend in the industry and market. In addition, their synthesis, potential applications and future of smart nanodevices in diagnosis of diseases and their use as smart clinical devices is covered. Users will find sections on recent advances in interdisciplinary research on the processing, morphology, structure and properties of nanostructured materials and their applications in drug delivery for various diseases such as cancer, tuberculosis, Alzheimer disease, ophthalmic diseases, and more. Offers a comprehensive coverage of the therapeutics and smart nanodevices as diagnostic tools and their potential clinical applications in biosensing and bioimaging Includes a glimpse into the nano-biomaterials that are essential components in nanomedicines Describes nanodevices in the early diagnosis of the diseases Explains the nano-drug delivery system for the treatment of various diseases, including cancer, tuberculosis, Alzheimer disease, and ophthalmic diseases Encompasses all information, starting from the design of nano-biomaterials to their applications in theranostics

Author : Ram Prasad,Busi Siddhardha,Madhu Dyavaiah
Publisher : Springer Nature
Page : 461 pages
File Size : 44,7 Mb
Release : 2020-05-12
Category : Science
ISBN : 9783030403379

Get Book

Nanostructures for Antimicrobial and Antibiofilm Applications by Ram Prasad,Busi Siddhardha,Madhu Dyavaiah Pdf

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.

Author : Pandey Ravindra K,Dougherty Thomas J,Kessel David
Publisher : World Scientific
Page : 564 pages
File Size : 40,5 Mb
Release : 2016-03-24
Category : Science
ISBN : 9789814719667

Get Book

Handbook Of Photodynamic Therapy: Updates On Recent Applications Of Porphyrin-based Compounds by Pandey Ravindra K,Dougherty Thomas J,Kessel David Pdf

The main objective of this book is to present the recent applications of photodynamic therapy (PDT) in treating cancer and other diseases. The limitations associated with current PDT agents, and the synthetic designs that have been used in various laboratories are also discussed. The utility of certain tumor-avid agent for cancer imaging (fluorescence, PET, MRI) is also summarized. The book also includes the use of delivery vehicles, including nanoparticles in improving the tumor-specificity of the desired agents. The book is basically focused on the translational approach of drug development. By providing certain specific examples, a clear concept of moving a 'product' from the bench to bed-side is also discussed.To have a clear concept of drug development the book is divided in three parts — Medicinal Chemistry, Mechanistic and Clinical studies. Each part includes the contributions from the leading scientists with extensive experience in the respective field. The handbook is assembled by renowned scientists Dr Dougherty, known as the father of PDT, Dr Kessel, well known for his contributions on mechanism of PDT and Dr Pandey for his inventions in developing improved agents for PDT and cancer-imaging.