Antimicrobial Research And One Health In Africa

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Antimicrobial Research and One Health in Africa

Author : Akebe Luther King Abia,Sabiha Yusuf Essack
Publisher : Springer Nature
Page : 359 pages
File Size : 43,8 Mb
Release : 2023-02-27
Category : Science
ISBN : 9783031237966

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Antimicrobial Research and One Health in Africa by Akebe Luther King Abia,Sabiha Yusuf Essack Pdf

Antimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter unique masterpiece presents the AMR problem in African, addressing the various compartments of the One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR, especially in Africa. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos on their various sectors

One Health, 2nd Edition

Author : Jakob Zinsstag,Esther Schelling,Lisa Crump,Maxine Whittaker,Marcel Tanner,Craig Stephen
Publisher : CABI
Page : 459 pages
File Size : 44,7 Mb
Release : 2020-09-30
Category : Medical
ISBN : 9781789242577

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One Health, 2nd Edition by Jakob Zinsstag,Esther Schelling,Lisa Crump,Maxine Whittaker,Marcel Tanner,Craig Stephen Pdf

One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.

Antimicrobial Resistance

Author : Mihai Mares,Swee Hua Erin Lim,Kok-Song Lai,Romeo-Teodor Cristina
Publisher : BoD – Books on Demand
Page : 210 pages
File Size : 50,9 Mb
Release : 2021-03-03
Category : Medical
ISBN : 9781839624322

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Antimicrobial Resistance by Mihai Mares,Swee Hua Erin Lim,Kok-Song Lai,Romeo-Teodor Cristina Pdf

Tackling the realities of the antimicrobial resistance (AMR) situation today is no longer uncommon. Many battles have been fought in the past since the discovery of antibiotics between man and microbes. In the tussle of new antibiotic modifications, the transmission of resistant genes, both vertically and horizontally unveils yet another resistant attribute for the microbe, for it only to be faced with a more powerful, wide spectrum antibiotic; the cycle continues-and the winner is yet to be known. This book aims to provide some insight into various molecular mechanisms, agricultural mitigation methods, and the One Health applications to maybe, just maybe, tip the scales towards us.

One Health

Author : Kevin Bardosh
Publisher : Routledge
Page : 267 pages
File Size : 46,9 Mb
Release : 2016-02-12
Category : Business & Economics
ISBN : 9781317334965

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One Health by Kevin Bardosh Pdf

Zoonotic diseases – pathogens transmitted from animals to people – offer particularly challenging problems for global health institutions and actors, given the complex social-ecological dynamics at play. New forms of risk caused by unprecedented global connectivity and rapid social and environmental change demand new approaches. ‘One Health’ highlights the need for collaboration across sectors and disciplines to tackle zoonotic diseases. However, there has been little exploration of how social, political and economic contexts influence efforts to ‘do’ One Health. This book fills this gap by offering a much needed political economy analysis of zoonosis research and policy. Through ethnographic, qualitative and quantitative data, the book draws together a diverse number of case studies. These include chapters exploring global narratives about One Health operationalization and prevailing institutional bottlenecks; the evolution of research networks over time; and the histories and politics behind conflicting disease control approaches. The themes from these chapters are further contextualized and expanded upon through country-specific case studies – from Kenya, Zambia, Nigeria, Ghana and Sierra Leone – exploring the translation of One Health research and policy into the African context. This book is a valuable resource for academic researchers, students and policy practitioners in the areas of global health, agriculture and development.

Integrated approaches to health

Author : Simon R. Rüegg,Barbara Häsler,Jakob Zinsstag
Publisher : BRILL
Page : 255 pages
File Size : 41,8 Mb
Release : 2023-09-14
Category : Technology & Engineering
ISBN : 9789086868759

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Integrated approaches to health by Simon R. Rüegg,Barbara Häsler,Jakob Zinsstag Pdf

One Health addresses health challenges arising from the intertwined spheres of humans, animals and ecosystems. This handbook is the product of an interdisciplinary effort to provide science-based guidance for the evaluation of One Health and other integrated approaches to health. It guides the reader through a systems approach and framework to evaluate such approaches in a standardised way. It provides an overview of concepts and metrics from health and life sciences, social sciences, economics, and ecology that are relevant for the evaluation of the processes involved, as well as the characterisation of expected and unexpected outcomes of One Health initiatives. Finally, the handbook provides guidance and practical protocols to help plan and implement evaluations in order to generate new insights and provide meaningful information about the value of One Health. The handbook is intended for practitioners, researchers, evaluators as well as funders of integrated approaches to health and beyond.

Taking a Multisectoral One Health Approach : A Tripartite Guide to Addressing Zoonotic Diseases in Countries

Author : Food and Agriculture Organization of the United Nations,World Organization for Animal Health,World Health Organization
Publisher : Food & Agriculture Org.
Page : 166 pages
File Size : 46,7 Mb
Release : 2019-03-11
Category : Medical
ISBN : 9789251312360

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Taking a Multisectoral One Health Approach : A Tripartite Guide to Addressing Zoonotic Diseases in Countries by Food and Agriculture Organization of the United Nations,World Organization for Animal Health,World Health Organization Pdf

The 2018 FAO-OIE-WHO (Tripartite) zoonoses guide, “Taking A Multisectoral, One Health Approach: A Tripartite Guide to Addressing Zoonotic Diseases in Countries” (2018 TZG) is being jointly developed to provide member countries with practical guidance on OH approaches to build national mechanisms for multisectoral coordination, communication, and collaboration to address zoonotic disease threats at the animal-human-environment interface. The 2018 TZG updates and expands on the guidance in the one previous jointly-developed, zoonoses-specific guidance document: the 2008 Tripartite “Zoonotic Diseases: A Guide to Establishing Collaboration between Animal and Human Health Sectors at the Country Level”, developed in WHO South-East Asia Region and Western Pacific Region. The 2018 TZG supports building by countries of the resilience and capacity to address emerging and endemic zoonotic diseases such as avian influenza, rabies, Ebola, and Rift Valley fever, as well as food-borne diseases and antimicrobial resistance, and to minimize their impacts on health, livelihoods, and economies. It additionally supports country efforts to implement WHO International Health Regulations (2005) and OIE international standards, to address gaps identified through external and internal health system evaluations, and to achieve targets of the Sustainable Development Goals. The 2018 TZG provides relevant country ministries and agencies with lessons learned and good practices identified from country-level experiences in taking OH approaches for preparedness, prevention, detection and response to zoonotic disease threats, and provides guidance on multisectoral communication, coordination, and collaboration. It informs on regional and country-level OH activities and relevant unisectoral and multisectoral tools available for countries to use.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 41,5 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

WHO guidelines on use of medically important antimicrobials in food-producing animals

Author : World Health Organization
Publisher : World Health Organization
Page : 0 pages
File Size : 46,7 Mb
Release : 2017-11-10
Category : Business & Economics
ISBN : 9241550139

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WHO guidelines on use of medically important antimicrobials in food-producing animals by World Health Organization Pdf

WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.

Food Safety and Informal Markets

Author : Kristina Roesel,Delia Grace
Publisher : Routledge
Page : 285 pages
File Size : 54,9 Mb
Release : 2014-10-03
Category : Business & Economics
ISBN : 9781317593973

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Food Safety and Informal Markets by Kristina Roesel,Delia Grace Pdf

Animal products are vital components of the diets and livelihoods of people across sub-Saharan Africa. They are frequently traded in local, unregulated markets and this can pose significant health risks. This volume presents an accessible overview of these issues in the context of food safety, zoonoses and public health, while at the same time maintaining fair and equitable livelihoods for poorer people across the continent. The book includes a review of the key issues and 25 case studies of the meat, milk, egg and fish food sectors drawn from a wide range of countries in East, West and Southern Africa, as part of the "Safe Food, Fair Food" project. It describes a realistic analysis of food safety risk by developing a methodology of ‘participatory food safety risk assessment’, involving small-scale producers and consumers in the process of data collection in a data-poor environment often found in developing countries. This approach aims to ensure market access for poor producers, while adopting a realistic and pragmatic strategy for reducing the risk of food-borne diseases for consumers.

Global Health and the Future Role of the United States

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Committee on Global Health and the Future of the United States
Publisher : National Academies Press
Page : 385 pages
File Size : 43,8 Mb
Release : 2017-09-05
Category : Medical
ISBN : 9780309457668

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Global Health and the Future Role of the United States by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Committee on Global Health and the Future of the United States Pdf

While much progress has been made on achieving the Millenium Development Goals over the last decade, the number and complexity of global health challenges has persisted. Growing forces for globalization have increased the interconnectedness of the world and our interdependency on other countries, economies, and cultures. Monumental growth in international travel and trade have brought improved access to goods and services for many, but also carry ongoing and ever-present threats of zoonotic spillover and infectious disease outbreaks that threaten all. Global Health and the Future Role of the United States identifies global health priorities in light of current and emerging world threats. This report assesses the current global health landscape and how challenges, actions, and players have evolved over the last decade across a wide range of issues, and provides recommendations on how to increase responsiveness, coordination, and efficiency â€" both within the U.S. government and across the global health field.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 333 pages
File Size : 41,8 Mb
Release : 2003-03-26
Category : Medical
ISBN : 9780309168304

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The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

Author : National Academies Of Sciences Engineeri,National Academies of Sciences Engineering and Medicine,Health And Medicine Division,Board On Population Health And Public He,Board on Population Health and Public Health Practice,Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States
Publisher : National Academies Press
Page : 128 pages
File Size : 41,6 Mb
Release : 2022-07-20
Category : Medical
ISBN : 0309269458

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Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine by National Academies Of Sciences Engineeri,National Academies of Sciences Engineering and Medicine,Health And Medicine Division,Board On Population Health And Public He,Board on Population Health and Public Health Practice,Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States Pdf

The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Improving Food Safety Through a One Health Approach

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 418 pages
File Size : 53,8 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9780309259361

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Improving Food Safety Through a One Health Approach by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Sustainable Agriculture Reviews 46

Author : Harsh Panwar,Chetan Sharma,Eric Lichtfouse
Publisher : Springer Nature
Page : 245 pages
File Size : 44,7 Mb
Release : 2020-09-29
Category : Technology & Engineering
ISBN : 9783030530242

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Sustainable Agriculture Reviews 46 by Harsh Panwar,Chetan Sharma,Eric Lichtfouse Pdf

According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow evolutionary process that has been accelerated by human activities in health, environment and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book reviews the drivers, impact and mitigation of antimicrobial resistance, with focus on methods and targets.

The Use of Drugs in Food Animals

Author : National Research Council,Institute of Medicine,Food and Nutrition Board,Board on Agriculture,Committee on Drug Use in Food Animals,Panel on Animal Health, Food Safety, and Public Health
Publisher : National Academies Press
Page : 276 pages
File Size : 49,5 Mb
Release : 1999-01-12
Category : Medical
ISBN : 9780309175777

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The Use of Drugs in Food Animals by National Research Council,Institute of Medicine,Food and Nutrition Board,Board on Agriculture,Committee on Drug Use in Food Animals,Panel on Animal Health, Food Safety, and Public Health Pdf

The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.