Antiplatelet Agents

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Antiplatelet Agents

Author : Paolo Gresele,Gustav V. R Born,Carlo Patrono,Clive P. Page
Publisher : Springer Science & Business Media
Page : 616 pages
File Size : 45,7 Mb
Release : 2012-08-23
Category : Medical
ISBN : 9783642294235

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Antiplatelet Agents by Paolo Gresele,Gustav V. R Born,Carlo Patrono,Clive P. Page Pdf

Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.

Antiplatelet Agents—Advances in Research and Application: 2013 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 81 pages
File Size : 40,7 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481672900

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Antiplatelet Agents—Advances in Research and Application: 2013 Edition by Anonim Pdf

Antiplatelet Agents—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Platelet Aggregation Inhibitors in a concise format. The editors have built Antiplatelet Agents—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Platelet Aggregation Inhibitors in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antiplatelet Agents—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Antiplatelet Agents in Stroke Prevention

Author : Gergely Feher,David Hargroves,Zsolt Illes,Peter Klivenyi,Liping Liu,Laszlo Szapary
Publisher : Frontiers Media SA
Page : 106 pages
File Size : 43,8 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9782889716807

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Antiplatelet Agents in Stroke Prevention by Gergely Feher,David Hargroves,Zsolt Illes,Peter Klivenyi,Liping Liu,Laszlo Szapary Pdf

Antiplatelet Therapy in ACS and A-Fib

Author : Victor L. Serebruany,Dan Atar
Publisher : Karger Medical and Scientific Publishers
Page : 177 pages
File Size : 41,8 Mb
Release : 2012
Category : Medical
ISBN : 9783318021684

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Antiplatelet Therapy in ACS and A-Fib by Victor L. Serebruany,Dan Atar Pdf

Written by top experts in the field Platelets play a critical role in the pathophysiology of acute coronary syndromes (ACS) and thromboembolic complications associated with atrial fibrillation. Anticoagulant and antiplatelet therapies are central to the treatment of ACS and atrial fibrillation. Over the last several decades, a better understanding of the pathogenesis of coronary heart disease and atrial fibrillation has led to refinements in antithrombotic strategies and clinical outcomes. With this in mind, some of the issues outlined in this book are new insights in genetic testing and modification of individualized antiplatelet therapy based on rapid bedside platelet analyzers. Most importantly, the current update of pros and cons of novel antiplatelet agents such as prasugrel and ticagrelor are provided in detail. Conventional antiplatelet strategies with aspirin and clopidogrel are also discussed. Special attention is devoted to experimental antiplatelet agents like PAR-1 thrombin receptor antagonists or aptamers. The ability to focus on different diseases beyond ACS, including heart failure and atrial fibrillation, distinguishes this publication. Each chapter was written by top experts in the field and scientists with the utmost authority and expertise to provide cardiologists, internists, and clinical pharmacologists with the latest updates.

Antiplatelet Therapy In Ischemic Heart Disease

Author : Stephen D. Wiviott
Publisher : John Wiley & Sons
Page : 312 pages
File Size : 53,6 Mb
Release : 2009-01-26
Category : Medical
ISBN : 9781444303346

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Antiplatelet Therapy In Ischemic Heart Disease by Stephen D. Wiviott Pdf

* Draws from expertise of leaders in antiplatelet therapy * Easy-to-use layout enables rapid browsing * Edited by a member of the prestigious TIMI study group withlong-standing experience in the field

Antiplatelet Agents—Advances in Research and Application: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 67 pages
File Size : 46,6 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481616805

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Antiplatelet Agents—Advances in Research and Application: 2012 Edition by Anonim Pdf

Antiplatelet Agents—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Antiplatelet Agents in a concise format. The editors have built Antiplatelet Agents—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antiplatelet Agents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antiplatelet Agents—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Antiplatelet Therapy in Cardiovascular Disease

Author : Ron Waksman,Paul A. Gurbel,Michael A. Gaglia, Jr.
Publisher : John Wiley & Sons
Page : 363 pages
File Size : 49,9 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9781118494028

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Antiplatelet Therapy in Cardiovascular Disease by Ron Waksman,Paul A. Gurbel,Michael A. Gaglia, Jr. Pdf

Edited by a team of the world’s leading interventional cardiologists and educators, this new book is created with an eye to giving the reader a solid, practical, and clinically focused understanding of this important class of drugs, from basic science to a clear-headed discussion of complex topics such as combination therapies, drug-to-drug interactions, and resistance to antiplatelet agents. This important new book: Begins with a concise but thorough discussion of platelet biology and pathophysiology so that readers understand how antiplatelet agents work and why they produce such a varied range of complications, from minor GI upset to potentially life-threatening conditions such as neutropenia, a critical shortage of white blood cells. Thoroughly covers platelet function testing, including novel techniques. Clarifies current best practice regarding the use of antiplatelet agents in both chronic and acute cardiovascular disease. Reviews all types of antiplatelet agents – from aspirin to recently approved drugs – including indications, clinical outcomes, and side effects. Written by an international “who’s who” of experts in the field, Antiplatelet Therapy in Cardiovascular Disease also includes an entire section covering the use of antiplatelet drugs in PCIs, including percutaneous valve repair, which makes this text particularly essential to interventional cardiologists.

Antiplatelet Agents: Advances in Research and Application: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 80 pages
File Size : 45,5 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464934414

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Antiplatelet Agents: Advances in Research and Application: 2011 Edition by Anonim Pdf

Antiplatelet Agents: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Antiplatelet Agents in a concise format. The editors have built Antiplatelet Agents: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antiplatelet Agents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antiplatelet Agents: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Primary Angioplasty

Author : Timothy J Watson,Paul JL Ong,James E Tcheng
Publisher : Springer
Page : 338 pages
File Size : 40,5 Mb
Release : 2018-07-13
Category : Medical
ISBN : 9789811311147

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Primary Angioplasty by Timothy J Watson,Paul JL Ong,James E Tcheng Pdf

This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

Antiplatelet and Anticoagulation Therapy

Author : Albert Ferro,David A. Garcia
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 41,7 Mb
Release : 2012-10-13
Category : Medical
ISBN : 9781447142966

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Antiplatelet and Anticoagulation Therapy by Albert Ferro,David A. Garcia Pdf

This title will be presented as highly practical information pn pharmaceutical antiplatelet and anticoagulation therapy, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 120 and 250 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.

Interventional Cardiology

Author : George D. Dangas,Carlo Di Mario,Nicholas N. Kipshidze,Peter Barlis,Tayo Addo
Publisher : John Wiley & Sons
Page : 2479 pages
File Size : 49,8 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9781118975961

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Interventional Cardiology by George D. Dangas,Carlo Di Mario,Nicholas N. Kipshidze,Peter Barlis,Tayo Addo Pdf

Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website

Anticoagulants, Antiplatelets, and Thrombolytics

Author : Shaker A. Mousa
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 53,7 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9781592596584

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Anticoagulants, Antiplatelets, and Thrombolytics by Shaker A. Mousa Pdf

This collection of review articles highlights the latest development of antithrombotics and provides proven experimental methods for the further development of new and improved anticoagulants. Among the cutting-edge developments reviewed are the novel usage of low molecular weight heparins, such antithrombin agents as the hirudin, and such antiplatelet drugs as the GPIIb/IIIa inhibitors and ADP receptor antagonists.

Clopidogrel and the Newer P2y12 Antiplatelet Agents

Author : Michael P. Savage,David L. Fischman,Mamas A. Mamas
Publisher : Unknown
Page : 308 pages
File Size : 48,6 Mb
Release : 2019
Category : Medical
ISBN : 153614973X

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Clopidogrel and the Newer P2y12 Antiplatelet Agents by Michael P. Savage,David L. Fischman,Mamas A. Mamas Pdf

Cardiovascular disease remains the leading cause of death in the developed world. By preventing thromboembolic events such as heart attacks and strokes, antiplatelet drugs have become a cornerstone in the treatment of cardiovascular disease. Clopidogrel is a member of the thienopyridine family which inhibit ADP-induced platelet activation by irreversibly binding to the P2Y12 receptor. Clopidogrel is one of the most commonly used medications with over 9 million prescriptions written annually. It is utilized in the treatment of a wide variety of cardiovascular disorders including acute coronary syndromes (ACS), percutaneous coronary intervention (PCI) with stents, cerebrovascular disease, peripheral vascular disease, and structural heart interventions. Most often, clopidogrel is used in combination with low dose aspirin, providing dual antiplatelet therapy (DAPT). Newer, more potent P2Y12 inhibitors, prasugrel and ticagrelor, are now available as alternatives to clopidogrel. These newer agents have been shown to be more effective than clopidogrel in reducing ischemic events in patients with ACS. Recently a novel intravenous P2Y12 inhibitor, cangrelor, has become available for use during PCI in patients who have not been pretreated with an oral P2Y12 inhibitor. This book examines virtually all aspects of P2Y12 inhibitors - pharmacology, clinical uses, randomized trial results, guideline recommendations, and adverse drug effects. Important fundamental issues are reviewed including comparative pharmacology of P2Y12 inhibitors, randomized trials of clopidogrel in patients with coronary artery disease, DAPT duration after PCI, and role of platelet function testing. The newer P2Y12 inhibitors (prasugrel, ticagrelor, and cangrelor) receive special focus. Use of antiplatelet therapy in specific patient populations is discussed including patients with coronary bypass graft surgery, peripheral vascular disease, cerebrovascular disease, and structural heart disease. Management of antiplatelet therapy in patients who require anticoagulation is a particularly challenging clinical setting and is the topic of a featured review. Finally, adverse drug effects and reactions are examined in a section highlighting clopidogrel resistance, clopidogrel hypersensitivity, and bleeding complications. This book is designed to provide a comprehensive review of clopidogrel and the newer P2Y12 inhibitors. Towards that end, the authors have enlisted an internationally renowned group of experts as contributors. It is intended to be a resource for clinicians, scientists, pharmacologists, and all healthcare professionals involved in the management of cardiovascular disease.

Hepatotoxicity

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 48,8 Mb
Release : 1999
Category : Medical
ISBN : 0781719526

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Hepatotoxicity by Hyman J. Zimmerman Pdf

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia

Author : World Health Organization
Publisher : World Health Organization
Page : 81 pages
File Size : 47,7 Mb
Release : 2021-12-07
Category : Medical
ISBN : 9789240037540

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WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia by World Health Organization Pdf

This is an update to recommendations related to the use of anti-platelet agents for the prevention of pre-eclampsia. The recommendation in this document thus supersedes the previous WHO recommendations on antiplatelet agents for the prevention of pre-eclampsia as published in the 2011 guidelines, WHO recommendations for the prevention and treatment of pre-eclampsia and eclampsia. The recommendation now specifies the use of anti-platelet agents in women at moderate and high risk of pre-eclampsia to prevent the development of pre-eclampsia. The primary audience for these recommendations includes health professionals who are responsible for developing national and local health-care guidelines and protocols and those involved in the provision of care to women and their newborns during pregnancy, labour and childbirth, including midwives, nurses, general medical practitioners and obstetricians. The primary audience also includes managers of maternal and child health programmes, and relevant staff in ministries of health and educational and training institutions, in all settings.