Approaches In Integrative Bioinformatics

Author : Ming Chen,Ralf Hofestädt
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 52,6 Mb
Release : 2014-01-18
Category : Computers
ISBN : 9783642412813

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Approaches in Integrative Bioinformatics by Ming Chen,Ralf Hofestädt Pdf

Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics, and virtual cell approaches, as well as a number of applications of network biology. It helps to illustrate the value of integrative bioinformatics approaches to the life sciences. This book is intended for researchers and graduate students in the field of Bioinformatics. Professor Ming Chen is the Director of the Bioinformatics Laboratory at the College of Life Sciences, Zhejiang University, Hangzhou, China. Professor Ralf Hofestädt is the Chair of the Department of Bioinformatics and Medical Informatics, Bielefeld University, Germany.

Author : Ming Chen,Ralf Hofestädt
Publisher : Springer Nature
Page : 381 pages
File Size : 55,7 Mb
Release : 2022-04-15
Category : Medical
ISBN : 9789811667954

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Integrative Bioinformatics by Ming Chen,Ralf Hofestädt Pdf

This book provides an overview of the history of integrative bioinformatics and the actual situation and the relevant tools. Subjects cover the essential topics, basic introductions, and latest developments; biological data integration and manipulation; modeling and simulation of networks; as well as a number of applications of integrative bioinformatics. It aims to provide basic introduction of biological information systems and guidance for the computational analysis of systems biology. This book covers a range of issues and methods that unveil a multitude of omics data integration and relevance that integrative bioinformatics has today. It contains a unique compilation of invited and selected articles from the Journal of Integrative Bioinformatics (JIB) and annual meetings of the International Symposium on Integrative Bioinformatics.

Author : Julio Collado-Vides,Boris Magasanik,Temple Smith
Publisher : MIT Press
Page : 372 pages
File Size : 47,7 Mb
Release : 1996
Category : Bioinformatics
ISBN : 0262032392

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Integrative Approaches to Molecular Biology by Julio Collado-Vides,Boris Magasanik,Temple Smith Pdf

It charts the course of the emerging discipline of integrative molecular biology from macromolecular sequences to a biological (and theoretical) perspective, showing that novel integrative methodologies and paradigms are emerging at the confluence of such disciplines as computer science, logic, linguistics, and mathematics.

Author : Xiuzhen Huang,Jason H. Moore,Yu Zhang
Publisher : Cambridge University Press
Page : 183 pages
File Size : 45,6 Mb
Release : 2023-10-31
Category : Science
ISBN : 9781107114302

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Integrative Bioinformatics for Biomedical Big Data by Xiuzhen Huang,Jason H. Moore,Yu Zhang Pdf

The volume and complexity of biological and biomedical research continues to grow exponentially with cutting-edge technologies such as high-throughput DNA sequencing. Unfortunately, bioinformatics analysis is often considered only after data has been generated, which significantly limits the ability to make sense of complex Big Data. This unique book introduces the idea of no-boundary thinking (NBT) in biological and biomedical research, which aims to access, integrate, and synthesize data, information, and knowledge from bioinformatics to define important problems and articulate impactful research questions. NBT encourages interdisciplinary thinking from the outset so that research is hypothesis-driven rather than data-driven. This interdisciplinary volume brings together a team of bioinformatics specialists who draw on their own experiences with NBT to illustrate the importance of collaborative science. It will help stimulate discussion and application of NBT, and will appeal to all biomedical researchers looking to maximize their use of bioinformatics for making scientific discoveries.

Author : Qing Yan
Publisher : Academic Press
Page : 182 pages
File Size : 46,8 Mb
Release : 2017-04-18
Category : Computers
ISBN : 9780128043882

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Translational Bioinformatics and Systems Biology Methods for Personalized Medicine by Qing Yan Pdf

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field

Author : Manish Kumar Gupta,Pramod Katara,Sukanta Mondal,Ram Lakhan Singh
Publisher : Elsevier
Page : 434 pages
File Size : 46,6 Mb
Release : 2024-05-10
Category : Science
ISBN : 9780443160936

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Integrative Omics by Manish Kumar Gupta,Pramod Katara,Sukanta Mondal,Ram Lakhan Singh Pdf

Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic ‘step by step’ manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to ‘translational research’, i.e., drug discovery, drug target prediction, and precision medicine Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 44,7 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Author : Preeti Arivaradarajan,Gauri Misra
Publisher : Springer
Page : 148 pages
File Size : 44,9 Mb
Release : 2019-02-04
Category : Science
ISBN : 9789811329258

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Omics Approaches, Technologies And Applications by Preeti Arivaradarajan,Gauri Misra Pdf

This book is a concerted effort to put together the rapidly growing facets of biological data. It provides a platform for the readers to think about integrative approaches to solve complex biological problems. This fundamental book deals with the simplest concepts of omics to recent advancements in the field. The content is divided into seven chapters that provide insight into various omics approaches, omics technologies, and its applications. Each chapter delves into different molecular scales: genomics, transcriptomics, proteomics, and metabolomics. Further to provide a holistic view a chapter detailing microbiome has been included in the book. The sub-sections in the chapters is dedicated to introducing the various analytical tools such as next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA Seq and NMR spectroscopy. It entails a chapter focused on the bioinformatics resources for analysis of the omics data. In summary, this comprehensive book emphasizes the recent advancements in the study of biomolecules spanning from DNA to metabolites.

Author : Atul Kumar Upadhyay,R Sowdhamini,Virupaksh U. Patil
Publisher : Springer Nature
Page : 160 pages
File Size : 46,9 Mb
Release : 2021-03-19
Category : Science
ISBN : 9789813347915

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Bioinformatics for agriculture: High-throughput approaches by Atul Kumar Upadhyay,R Sowdhamini,Virupaksh U. Patil Pdf

This book illustrates the importance and significance of bioinformatics in the field of agriculture. It first introduces the basic concepts of bioinformatics, such as homologous sequence and gene function analyses, determination of protein structures, and discusses machine learning applications for an in-depth understanding of the desired genes and proteins based on commonly used bioinformatics software and tools, e.g. BLAST, molecular modelling, molecular-docking and simulations, protein-protein and domain-domain interactions. The book also describes recent advances in the high-throughput analysis of whole genome and transcriptome using next-generation sequencing platforms, and functional proteome studies. It also examines the role of computational biology in understanding and improving the nutrient quality and yield of crops. Lastly, the book explores a comprehensive list of applications of bioinformatics to improve plant yield, biomass, and health, and the challenges involved.

Author : Rune Matthiesen
Publisher : Humana Press
Page : 390 pages
File Size : 46,8 Mb
Release : 2010-05-04
Category : Science
ISBN : 1607613824

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Bioinformatics Methods in Clinical Research by Rune Matthiesen Pdf

Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen. In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers.

Author : Havukkala Ilkka
Publisher : World Scientific Publishing Company
Page : 324 pages
File Size : 53,9 Mb
Release : 2010-06-23
Category : Science
ISBN : 9789813107083

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Biodata Mining And Visualization: Novel Approaches by Havukkala Ilkka Pdf

There is a lack of an exposition on interdisciplinary and innovative methods of data mining and visualization for biodata. This book fills the gap by introducing an interdisciplinary set of the most recent methods and references on novel techniques from artificial intelligence, data mining, engineering, pattern recognition, and ontological data mining fields that are applicable to bioinformatics. The latest novel approaches are explained in detail, their advantages and disadvantages are summarized, and pointers to the future development of new applications are given. By widening the pool from which biologists and bioinformaticians can adopt methods for biodata mining and visualization, computational data mining experts in nonbiological fields are also encouraged to utilize their expertise in order to contribute to the progress of computational biology, thus enhancing the collaboration between these two disciplines.

Author : Stephen A. Krawetz,David D. Womble
Publisher : Springer Science & Business Media
Page : 776 pages
File Size : 42,8 Mb
Release : 2003-01-31
Category : Computers
ISBN : 1588290646

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Introduction to Bioinformatics by Stephen A. Krawetz,David D. Womble Pdf

CD-ROM contains: chapter illustrations -- full and trial versions of programs.

Author : Sergio Cimerman,Alfonso J. Rodriguez-Morales
Publisher : Frontiers Media SA
Page : 242 pages
File Size : 46,6 Mb
Release : 2023-09-28
Category : Medical
ISBN : 9782832534434

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New therapeutic approaches for SARS-CoV-2/COVID-19 by Sergio Cimerman,Alfonso J. Rodriguez-Morales Pdf

Author : CHIRANJIB CHAKRABORTY.
Publisher : Unknown
Page : 128 pages
File Size : 44,8 Mb
Release : 2008
Category : Electronic
ISBN : 9351303365

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BIOINFORMATICS by CHIRANJIB CHAKRABORTY. Pdf

Author : Anonim
Publisher : ScholarlyEditions
Page : 1824 pages
File Size : 42,9 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464964176

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Issues in Bioengineering and Bioinformatics: 2011 Edition by Anonim Pdf

Issues in Bioengineering and Bioinformatics: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioengineering and Bioinformatics. The editors have built Issues in Bioengineering and Bioinformatics: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioengineering and Bioinformatics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Bioengineering and Bioinformatics: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.