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Attention, Genes and ADHD by Florence Levy,David Hay Pdf
This book focuses on the application of behaviour genetic approaches to twin studies, and reviews diagnostic to Attention Deficit Hyperactivity Disorder (ADHD), the relationships between reading, spelling and ADHD, and family and genetic influences on speech and speech and language.
Attention, Genes, and Developmental Disorders by Kim Cornish,John Wilding Pdf
What is attention? How does it go wrong? Do attention deficits arise from genes or from the environment? Can we cure it with drugs or training? Are there disorders of attention other than deficit disorders? The past decade has seen a burgeoning of research on the subject of attention. This research has been facilitated by advances on several fronts: New methods are now available for viewing brain activity in real time, there is expanding information on the complexities of the biochemistry of neural activity, individual genes can be isolated and their functions identified, analysis of the component processes included under the broad umbrella of "attention" has become increasingly sophisticated, and ingenious methods have been devised for measuring typical and atypical development of these processes, from infancy into childhood, and then into adulthood. In this book, Kim Cornish and John Wilding are concerned with attention and its development, both typical and atypical, particularly in disorders with a known genetic etiology or assumed genetic linkage. Tremendous advances across seemingly diverse disciplines - molecular genetics, pediatric neurology, child psychiatry, developmental cognitive neuroscience, and education - have culminated in a wealth of new methods for elucidating disorders at multiple levels, possibly paving the way for new treatment options. Cornish and Wilding use three specific-yet-interlinking levels of analysis: genetic blueprint (genotype), the developing brain, and the behavioral-cognitive outcomes (phenotype), as the basis for charting the attention profiles of six well-documented neurodevelopmental disorders: ADHD, autism, fragile X syndrome, Down syndrome, Williams syndrome, and 22q11 deletion syndrome. Their overarching aim in this book is to provide the most authoritative and extensive account to date of disorder-specific attention profiles and their development from infancy through adolescence.
ADHD in Adults by Russell A. Barkley,Kevin R. Murphy,Mariellen Fischer Pdf
Providing a new perspective on ADHD in adults, this compelling book analyzes findings from two major studies directed by leading authority Russell A. Barkley. Groundbreaking information is presented on the significant impairments produced by the disorder across major functional domains and life activities, including educational outcomes, work, relationships, health behaviors, and mental health. Thoughtfully considering the treatment implications of these findings, the book also demonstrates that existing diagnostic criteria do not accurately reflect the way ADHD is experienced by adults, and points the way toward developing better criteria that center on executive function deficits. Accessible tables, figures, and sidebars encapsulate the study results and methods.
Attention Deficit Hyperactivity Disorder by Luis Augusto Rhode,Stephen V. Faraone Pdf
This comprehensive new issue of Clinics in Child & Adolescent Psychiatry explores the hugely important and ever-changing topic of ADHD. Guest Editors Luis Rohde and Stephen Faraone focus on such timely topics as Neurobiology of ADHD, Frontiers Between ADHD and Bipolar Disorder, Psychosocial Interventions, and Psychopharmacological Interventions. This is a must-have reference for any clinician dealing with young patients.
Oxford Textbook of Attention Deficit Hyperactivity Disorder by Tobias Banaschewski,David Coghill,Alessandro Zuddas Pdf
Oxford Textbook of Attention Deficit Hyperactivity Disorder is an authoritative, multi-disciplinary text covering the diagnosis, assessment and management of patients with ADHD.
The Wiley Handbook of Cognitive Control by Tobias Egner Pdf
Covering basic theory, new research, and intersections with adjacent fields, this is the first comprehensive reference work on cognitive control – our ability to use internal goals to guide thought and behavior. Draws together expert perspectives from a range of disciplines, including cognitive psychology, neuropsychology, neuroscience, cognitive science, and neurology Covers behavioral phenomena of cognitive control, neuroanatomical and computational models of frontal lobe function, and the interface between cognitive control and other mental processes Explores the ways in which cognitive control research can inform and enhance our understanding of brain development and neurological and psychiatric conditions
Developmental Psychopathology and Wellness by James J. Hudziak Pdf
A major benchmark in the understanding of psychiatric illness in children and adolescents, Developmental Psychopathology and Wellness reports on progress in identifying genetic and environmental influences on emotional-behavioral disorders. A team of 22 international authorities presents work that changes the way child psychiatry and clinical psychology are conceptualized, debunking misconceptions about depression, antisocial behavior, and other conditions to enhance our understanding of the causes of child psychopathology -- and improve the ways we treat these disorders. Coverage of basic principles describes the influence of genomic medicine, as explained by trailblazers in the field who demonstrate the importance of the developmental perspective. Chapters on gene-environment interaction review the important concepts of personality and temperament, cognition, and sex -- including findings from molecular genetic investigations on adolescent cognition, temperament, and brain function. Disorder-based examples show how emotional-behavioral illness and wellness attest to the interaction of genetic and environmental factors over time, providing new insight into the study of anxious depression, ADHD, autism, and antisocial personality disorders. And in considering how we can bridge the gap between research and clinical applications, Dr. Hudziak describes his family-based gene-environment approach as a means of better understanding etiopathology and treatment. Among the other significant contributions: Thomas Achenbach focuses on the importance of culture in understanding the genetic and environmental impact on children, with insights into measuring these sources of influence. Joan Kaufman reports on her seminal work on the genetic and environmental modifiers of risk and resilience in child abuse, relating maltreatment to other forms of environmental risk, genetic mediation, and reactivity. D. I. Boomsma describes the genetic architecture of childhood worry, presenting data from an extraordinary sample of 30,000 twin pairs. Frank Verhulst draws on a 14-year study to detail the advantages of the developmental perspective in understanding antisocial behavior. Stephen Faraone offers guidelines for moving beyond statistics to document the functional significance of DNA variants associated with psychopathology. As the contributors ably demonstrate, these new approaches to the care and treatment of at-risk children are applicable to daily practice, teaching, and research. Developmental Psychopathology and Wellness shows that these psychopathologies are not a matter of nature versus nurture or genes versus environment, but rather an intertwining web of them all.
Hyperactivity and Attention Disorders of Childhood by Seija Sandberg Pdf
In this 2002 edition, a distinguished, international team of researchers and clinicians revisit attention-deficit and hyperactivity disorders in young people.
ADHD and Hyperkinetic Disorder by Tobias Banaschewski,Alessandro Zuddas,Philip Asherson,Jan Buitelaar,David Coghill,Marina Danckaerts,Manfred Döpfner,Luis Augusto Rohde,Edmund Sonuga-Barke,Eric Taylor Pdf
This pocketbook serves as a concise and practical guide to the management of ADHD for child and adolescent psychiatrists and child psychologists, paediatricians, trainees, psychiatric specialist nurses, interested general practitioners, and other mental health professionals. The pocketbook provides a user-friendly introduction to the clinical understanding, evaluation, and treatment of ADHD. This edition has been updated to include new DSM-5 diagnostic criteria (May 2013) and to reflect more published studies on ADHD in the adult population, along with new data on the CNS stimulant drug LDX (Lisdexamfetamine Dimesylate).
A newly revised and updated edition of the classic guide to reframing our view of ADHD and embracing its benefits • Explains that people with ADHD are not disordered or dysfunctional, but simply “hunters in a farmer’s world”--possessing a unique mental skill set that would have allowed them to thrive in a hunter-gatherer society • Offers concrete non-drug methods and practices to help hunters--and their parents, teachers, and managers--embrace their differences, nurture creativity, and find success in school, at work, and at home • Reveals how some of the world’s most successful people can be labeled as ADHD hunters, including Benjamin Franklin, Thomas Edison, and Andrew Carnegie With 10 percent of the Western world’s children suspected of having Attention Deficit Disorder, or ADHD, and a growing number of adults self-diagnosing after decades of struggle, the question must be raised: How could Nature make such a “mistake”? In this updated edition of his groundbreaking classic, Thom Hartmann explains that people with ADHD are not abnormal, disordered, or dysfunctional, but simply “hunters in a farmer’s world.” Often highly creative and single-minded in pursuit of a self-chosen goal, those with ADHD symptoms possess a unique mental skill set that would have allowed them to thrive in a hunter-gatherer society. As hunters, they would have been constantly scanning their environment, looking for food or threats (distractibility); they’d have to act without hesitation (impulsivity); and they’d have to love the high-stimulation and risk-filled environment of the hunting field. With our structured public schools, office workplaces, and factories those who inherit a surplus of “hunter skills” are often left frustrated in a world that doesn’t understand or support them. As Hartmann shows, by reframing our view of ADHD, we can begin to see it not as a disorder, but as simply a difference and, in some ways, an advantage. He reveals how some of the world’s most successful people can be labeled as ADHD hunters and offers concrete non-drug methods and practices to help hunters--and their parents, teachers, and managers--embrace their differences, nurture creativity, and find success in school, at work, and at home. Providing a supportive “survival” guide to help fine tune your natural skill set, rather than suppress it, Hartmann shows that each mind--whether hunter, farmer, or somewhere in between--has value and great potential waiting to be tapped.
Genetic Risk and Phenotypic Variation in Attention Deficit Hyperactivity Disorder [microform] by Jennifer Crosbie Pdf
Genetic factors play a major role in the etiology of Attention Deficit Hyperactivity Disorder (ADHD), as is evident from family, twin and adoption studies. Molecular genetic research has implicated a number of genes as risk factors for ADHD. Despite solid evidence the mode of genetic transmission has been elusive. The difficulty in identifying genes for ADHD may be, at least in part, a reflection of the complex relationship between the causative genes underlying the disorder and their phenotypic expression at the behavioural level. Objective: The immediate goal of this thesis was to investigate specific behavioural traits and potential cognitive endophenotypes in relation to three candidate genes of ADHD; the dopamine transporter (DAT1), dopamine receptor D4 (DRD4), and synaptosomal-associated protein of 25 kDa (SNAP-25). Rather than relying on ADHD as categorical diagnosis of affected or unaffected, inattention and hyperactivity-impulsivity are investigated independently as continuous traits to determine the relationship with the specific genetic risks for ADHD. Different informants were investigated independently by evaluating symptoms reported by parents and by teachers across the two behavioural dimensions. Inhibitory control and working memory were evaluated to determine the relationship with the genetic risks and argued as potential cognitive endophenotypes. Results: The 4-repeat allele of the 48 bp repeat located in the third exon of DRD4 was linked with lower parent-reported symptom scores of inattention. No significant results were found for teacher reported behaviours. Better inhibitory control was linked with the 4-repeat allele. Inattention and hyperactivity-impulsivity as reported by parent, by not teacher, were linked with a risk haplotype of DAT1. No relationship was found between inhibitory control and DAT1. SNAP-25 was linked with higher ratings of both inattention and hyperactivity-impulsivity. No relationship with deficits in verbal working memory was found for any of the genes investigated. In contrast, better working memory was linked with DAT1. Conclusions: The relationship between behavioural and cognitive traits showed variation across the candidate genes investigated, as was broadly predicted. Differentiation of the relationship of traits across genetic risk factors was evident for behavioural dimensions and for informant. The study findings support inhibitory control as a genetically informative endophenotype for ADHD. Overall, these results highlight the potential of quantitative approaches for the elucidation of genetic traits, and underlying genes, in ADHD.
Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent neurodevelopmental disorder. Previously, it was considered a disorder that affected children only. Recently, however, there is no doubt that ADHD can affect adults as well, but with different clinical presentation. Thus, it is critical to understand how the clinical picture of the disorder changes with development. Traditional ADHD diagnostic procedures are broadening and incorporating new entities like endophenotypes. Comorbidity is a rule, especially if ADHD is not recognized and treated early. New genetic studies bring deeper and more concise knowledge about the disorder’s etiology. This book addresses these aspects of ADHD to bring about more clarity and understanding of the disorder.
